Genetic screening of gamete donors: ethical issues
... In addition to taking a medical and family history, donor screening may also include genetic testing for specific conditions. However, professional guidelines differ with regard to what this should include. One remarkable difference concerns the need for standard karyotyping (testing for chromosomal ...
... In addition to taking a medical and family history, donor screening may also include genetic testing for specific conditions. However, professional guidelines differ with regard to what this should include. One remarkable difference concerns the need for standard karyotyping (testing for chromosomal ...
Comprehension Questions
... (b) What is the most likely mode of inheritance for color-blindness in Joe’s family? X-linked recessive. Only males have the trait, and they inherit the trait from their mothers, who are carriers. The trait is never passed from father to son. (c) If Joe marries a woman who has no family history of c ...
... (b) What is the most likely mode of inheritance for color-blindness in Joe’s family? X-linked recessive. Only males have the trait, and they inherit the trait from their mothers, who are carriers. The trait is never passed from father to son. (c) If Joe marries a woman who has no family history of c ...
Drosophila
... • Developmental biologists agree on several conclusions about these results. • First, nuclei do change in some ways as cells differentiate. • While the DNA sequences do not change, chromatin structure and methylation may. ...
... • Developmental biologists agree on several conclusions about these results. • First, nuclei do change in some ways as cells differentiate. • While the DNA sequences do not change, chromatin structure and methylation may. ...
A locus in Pristionchus pacificus that is responsible for the ability to
... mapping, we identify a region on chromosome V that is responsible for maintaining fertility at higher temperatures. Thus, we conclude that fitness of P. pacificus at high temperature is under genetic control, suggesting that it could be subject to natural selection. KEY WORDS: Temperature, Pristionc ...
... mapping, we identify a region on chromosome V that is responsible for maintaining fertility at higher temperatures. Thus, we conclude that fitness of P. pacificus at high temperature is under genetic control, suggesting that it could be subject to natural selection. KEY WORDS: Temperature, Pristionc ...
Sex Determination and Sex-Linked Characteristics
... genetically distinct from their parents; most often, two parents contribute genes to their offspring and the genes are assorted into new combinations through meiosis. Among most eukaryotes, sexual reproduction consists of two processes that lead to an alternation of haploid and diploid cells: meiosi ...
... genetically distinct from their parents; most often, two parents contribute genes to their offspring and the genes are assorted into new combinations through meiosis. Among most eukaryotes, sexual reproduction consists of two processes that lead to an alternation of haploid and diploid cells: meiosi ...
Two Cases of Pure Hair Nail Ectodermal Dysplasia in Two Yemeni
... be seen within the hair follicles (Figure 1b). All 20 nails were distally dystrophic and sloped (Figures 1c and 1d). Teeth and sweat glands were not affected. The histological examination of the scalp showed severely reduced number of structurally disorganized hair follicles (Figure 1e). The patient ...
... be seen within the hair follicles (Figure 1b). All 20 nails were distally dystrophic and sloped (Figures 1c and 1d). Teeth and sweat glands were not affected. The histological examination of the scalp showed severely reduced number of structurally disorganized hair follicles (Figure 1e). The patient ...
What causes Autism Spectrum Disorder (ASD)?
... one child has an ASD, then the other will be affected between 36-95% of the time. In nonidentical twins, if one child has an ASD, then the other is affected between 0-31% of the time. The patterns of genetic inheritance are complex, with the involvement of multiple genes, rather than a simple domina ...
... one child has an ASD, then the other will be affected between 36-95% of the time. In nonidentical twins, if one child has an ASD, then the other is affected between 0-31% of the time. The patterns of genetic inheritance are complex, with the involvement of multiple genes, rather than a simple domina ...
Genetic studies of psoriasis and psoriatic arthritis
... PSORS5 yielded no significant association. It is therefore unlikely that they harbor the genetic cause of psoriasis at this locus. Fine-mapping of the PSORS5 region revealed both point-wise and haplotype associations that might contribute to psoriasis susceptibility. The only gene within this region ...
... PSORS5 yielded no significant association. It is therefore unlikely that they harbor the genetic cause of psoriasis at this locus. Fine-mapping of the PSORS5 region revealed both point-wise and haplotype associations that might contribute to psoriasis susceptibility. The only gene within this region ...
The genetic consequences of selection in natural populations
... observed patterns of allele frequency or nucleotide variation (Barrett & Hoekstra 2011). Thus, observational approaches often use population genetic modelling, simulations, and statistical analysis to rule out the possibility that only genetic drift or other neutral forces (e.g., demographic changes ...
... observed patterns of allele frequency or nucleotide variation (Barrett & Hoekstra 2011). Thus, observational approaches often use population genetic modelling, simulations, and statistical analysis to rule out the possibility that only genetic drift or other neutral forces (e.g., demographic changes ...
Sc!ence - Return to Home Page
... In 1945, McClintock discovered that when corn chromosomes had broken and reattached several times, one cell would completely lose a chunk of genetic material that then showed up in another cell. She discovered that chromosomes include switches that turn genes on and off and activators that can make ...
... In 1945, McClintock discovered that when corn chromosomes had broken and reattached several times, one cell would completely lose a chunk of genetic material that then showed up in another cell. She discovered that chromosomes include switches that turn genes on and off and activators that can make ...
Conservation of Brachyury (T) genes in amphioxus and vertebrates
... notochord development preceded vertebrate origins; in contrast, expression in early mesoderm (other than notochord) probably evolved later. The data do not resolve whether this latter expression, and its associated developmental role, is restricted to vertebrates in general, or only to higher verteb ...
... notochord development preceded vertebrate origins; in contrast, expression in early mesoderm (other than notochord) probably evolved later. The data do not resolve whether this latter expression, and its associated developmental role, is restricted to vertebrates in general, or only to higher verteb ...
Hypergraph and protein function prediction with gene expression data
... prediction problem. In this paper, we will develop the symmetric normalized, random walk, and un-normalized hypergraph Laplacian based semi-supervised learning methods and apply these three methods to the hypergraph constructed from gene expression data available from [11] by applying k-mean cluster ...
... prediction problem. In this paper, we will develop the symmetric normalized, random walk, and un-normalized hypergraph Laplacian based semi-supervised learning methods and apply these three methods to the hypergraph constructed from gene expression data available from [11] by applying k-mean cluster ...
Sequence comparison of aflR from different Aspergillus species
... 1998). Although an exact function for this protein has not yet been identified, preliminary evidence suggests that it modulates AflR activity (P.-K. Chang, unpublished results). AflJ was found to be necessary for accumulation of some of the early precursor metabolites involved in the aflatoxin biosynthe ...
... 1998). Although an exact function for this protein has not yet been identified, preliminary evidence suggests that it modulates AflR activity (P.-K. Chang, unpublished results). AflJ was found to be necessary for accumulation of some of the early precursor metabolites involved in the aflatoxin biosynthe ...
Evidence for Variable Selective Pressures at a
... It is well known that considering the age of an individual mutation provides only weak evidence for either neutrality or deleteriousness because slightly deleterious mutations can persist for a long time in a population and even become fixed at the species level (Kimura 1983). A young mutation per s ...
... It is well known that considering the age of an individual mutation provides only weak evidence for either neutrality or deleteriousness because slightly deleterious mutations can persist for a long time in a population and even become fixed at the species level (Kimura 1983). A young mutation per s ...
Identification and comparative analysis of accessory gland
... probed the libraries with female cDNA (cDNA from wholebody extracts of Allonemobius and Gryllus females, respectively) to identify and eliminate ‘‘housekeeping’’ genes. To do this we used a plate replicator to spot the library (colonies grown independently in liquid medium) onto nylon membranes plac ...
... probed the libraries with female cDNA (cDNA from wholebody extracts of Allonemobius and Gryllus females, respectively) to identify and eliminate ‘‘housekeeping’’ genes. To do this we used a plate replicator to spot the library (colonies grown independently in liquid medium) onto nylon membranes plac ...
Haplotypes at LBX1 Have Distinct Inheritance Patterns with
... in a test for deviation from Hardy-Weinberg Equilibrium (HWE) in cases and controls; (b) Minor allele frequency 3%; (c) SNP call rate 98%; and (d) visual inspection of genotype clusters for the 500 most strongly associated SNPs. SNPs from copy number variant regions and SNPs known to have frequent ...
... in a test for deviation from Hardy-Weinberg Equilibrium (HWE) in cases and controls; (b) Minor allele frequency 3%; (c) SNP call rate 98%; and (d) visual inspection of genotype clusters for the 500 most strongly associated SNPs. SNPs from copy number variant regions and SNPs known to have frequent ...
Key area 2: Plant and animal breeding by manipulation of heredity
... However, if F1 hybrids are allowed to interbreed with one another, the F2 generation can be too genetically diverse and many will lack the improved characteristics. ...
... However, if F1 hybrids are allowed to interbreed with one another, the F2 generation can be too genetically diverse and many will lack the improved characteristics. ...
European Journal of Plant Pathology
... The kdgR gene (kdg for 2-keto-3-deoxygluconate general repressor) product, for example, which negatively regulates the genes involved in pectin degradation by binding to the operator regions, has a high degree of similarity to the deduced amino acid sequence of KdgR in E. coli (Liu et al., 1999; Rev ...
... The kdgR gene (kdg for 2-keto-3-deoxygluconate general repressor) product, for example, which negatively regulates the genes involved in pectin degradation by binding to the operator regions, has a high degree of similarity to the deduced amino acid sequence of KdgR in E. coli (Liu et al., 1999; Rev ...
ARTICLE IN PRESS
... same PCR and cycling conditions as described above. After confirming that the re-amplified fragments co-migrated with the expected 16S rRNA V3 PCR fragments of the original samples on DGGE gels, the re-amplified fragments were subjected to another round of PCR using primers 518R and 357F to remove the ...
... same PCR and cycling conditions as described above. After confirming that the re-amplified fragments co-migrated with the expected 16S rRNA V3 PCR fragments of the original samples on DGGE gels, the re-amplified fragments were subjected to another round of PCR using primers 518R and 357F to remove the ...
uncorrected page proofs
... they die off, and the flowers appear in autumn on their own (see figure 14.2). This simple but beautiful plant is poisonous. Deaths have occurred, often after a person has mistaken the plant for wild garlic and eaten its bulb-like corm. The poison in the autumn crocus is an alkaloid, known as colchic ...
... they die off, and the flowers appear in autumn on their own (see figure 14.2). This simple but beautiful plant is poisonous. Deaths have occurred, often after a person has mistaken the plant for wild garlic and eaten its bulb-like corm. The poison in the autumn crocus is an alkaloid, known as colchic ...