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Package 'MatrixEQTL'
Package 'MatrixEQTL'

... Matrix eQTL can perform separate analysis for local (cis) and distant (trans) eQTLs. For such analysis one has to set the cis-analysis specific parameters pvOutputThreshold.cis > 0, cisDist, snpspos and genepos in the call of Matrix_eQTL_main function. A gene-SNP pair is considered local if the dist ...
Imprinting in the endosperm: a possible role in preventing wide
Imprinting in the endosperm: a possible role in preventing wide

... Reproductive isolation is considered to play a key part in evolution, and plants and animals have developed a range of strategies that minimize gene flow between species. In plants, these strategies involve either pre-zygotic barriers, such as differences in floral structure and pollen–stigma recogn ...
Tracing the Thread of Plastid Diversity through the Tapestry of Life
Tracing the Thread of Plastid Diversity through the Tapestry of Life

... Herrmann 1998). Those plastid proteins not encoded in the plastid genome are encoded in the nuclear genome and must be targeted to the plastid. Three mechanisms underlie this reduction of the plastid genome; gene loss, substitution, and transfer. First, in the case of gene loss, genes that no longer ...
Isolation and characterization of novel mutants of Arabidopsis
Isolation and characterization of novel mutants of Arabidopsis

... The procedures for mutagenesis, Ti plasmid-mediated transformation and plant regeneration are being studied. Using this flowering plant, we have attempted to take a genetic approach to understand the process of flower development and morphogenesis. The very first and most fundamental step in the stu ...
Methods and Logic: Gregor Mendel Experiments in Plant
Methods and Logic: Gregor Mendel Experiments in Plant

... • Mendel described basic genetic inheritance, and pioneered the terms recessive and dominant. • He leaves the understanding of the coloring of ornamental flowers to future experiments. • He also notes that there are great differences between plants and animals that are bred in captivity to animals t ...
Nodal signaling and the zebrafish organizer
Nodal signaling and the zebrafish organizer

... end of gastrulation (Heisenberg and Nüsslein-Volhard, 1997). The same sqt allele was isolated independently from a related stock of fish as a spontaneous mutation that enhanced the phenotype of cyc, and further phenotypic characterization revealed that sqt mutants display reduced expression of dorsa ...
Speed, dissipation, and error in kinetic proofreading Arvind Murugan
Speed, dissipation, and error in kinetic proofreading Arvind Murugan

... T R is very large compared to typical reaction time scales in the network, because γ ≪ 1 and θ23 ≪ 1. In the following, we will address the issue of this slowing down and the related expenditure of energy. We begin by generalizing the results of Hopfield’s kinetic proofreading scheme to more complex ...
Minimum SNPs version 2043 user manual
Minimum SNPs version 2043 user manual

... In MLST the number of nucleotide differences between alleles is ignored and sequences are given different allele numbers whether they differ at a single nucleotide site or at many sites. The rationale is that a single genetic event resulting in a new allele can occur by a point mutation (altering on ...
Human mitochondrial transfer RNAs: Role of pathogenic
Human mitochondrial transfer RNAs: Role of pathogenic

... Most of the observed mtDNA changes represent neutral polymorphisms and have been used to track human migrations.70 The large prevalence of variations in tRNA genes calls for the elucidation of their pathogenicity. In addition, clinical misattribution of pathogenicity is an important issue due to the ...
Package `fcros`
Package `fcros`

... Author Doulaye Dembele Maintainer Doulaye Dembele Depends R (>= 3.1.0) Description A fold change rank based method is presented to search for genes with changing expression and to detect recurrent chromosomal copy number aberrations. This method may be useful for high-throughput b ...
The Genetic Principles of Crossbreeding
The Genetic Principles of Crossbreeding

... Crossbreeding is the mating of two individuals with different breed makeups. It is widely used in commercial beef production because of the benefits it has to offer cow-calf producers. Improvements in efficiency can be dramatic if appropriate breed combinations are used. Crossbreeding does not elimi ...
Mapping Polygenes - University of Warwick
Mapping Polygenes - University of Warwick

... B ackcross or F2/F3 populations have been used most commonly for detecting linkage between molecular markers and genes controlling quantitative traits (34, 43, 52, 55, 62). In species where severe inbreeding is tolerated, recombinant inbred populations (derived by inbreeding F2 progeny until they be ...
of Lactobacillus pentosus
of Lactobacillus pentosus

... Lactobadilus. Lactobacilli are members of the lactic acid bacteria, a group of microorganisms that is widely used in various food and feed fermentations. These non-pathogenic, Gram-positive, bacteria appear as small chains of rod-shaped ceils with variable length, depending on the strain and physiol ...
High diversity of the `Spumella-like` flagellates: an investigation
High diversity of the `Spumella-like` flagellates: an investigation

... 1998). Even in benthic sites, colourless chrysophytes make up to 30%, but usually much less (Arndt et al., 2000). In addition, the chrysophyte genera Ochromonas and Poterioochromonas are assumed to be among the dominant mixotrophs (Bennet et al., 1990). The primary mode of nutrition of these mixotro ...
Partitioning Genetic Variance
Partitioning Genetic Variance

... many further equations may be derived.2 Additive genetic variance For a single locus, the total genetic variance is partitioned into two types of variance, the additive genetic variance and dominance variance. Here we give the derivation for additive genetic variance. We begin by noting the orthogon ...
Down syndrome: characterisation of a case with partial trisomy of
Down syndrome: characterisation of a case with partial trisomy of

... similar chromosomal arrangements will help to clarify this issue. The study presented here highlights several important aspects of the diagnosis of cases of partial trisomy 21. The combination of chromosome painting and FISH using YAC clones as probes permits a rapid characterisation of the chromoso ...
Evolutionary History of Free-Swimming and
Evolutionary History of Free-Swimming and

... avoid the effect of a sequence with a high substitution rate on tree topology, I did not include Herdmania in the analyses. Phylogenetic analyses were performed on 1,461 confidently aligned sites by the NJ (Saitou and Nei 1987), ML (Felsenstein 1981), and MP methods. The topologies of phylogenetic t ...
Low-Level Analysis of Affymetrix Data
Low-Level Analysis of Affymetrix Data

... • NB: High affinity is not the same as specificity – Probe can give high signal to intended target and also to other transcripts ...
video slide - Dublin City Schools Home
video slide - Dublin City Schools Home

... • While transgenic animals are currently used to produce potentially useful proteins, none are yet found in our food supply. • It is possible that DNA technology will eventually replace traditional animal breeding. ...
Genetic Basis for Osmosensitivity and Genetic Instability of the Wine
Genetic Basis for Osmosensitivity and Genetic Instability of the Wine

... during osmotic stress lead to a redox imbalance in the yeast cell (NADH:NAD +). To compensate for this redox shift, it has been suggested that yeast may produce acetic acid as a redox sink to convert NAD + back to NADH (Blomberg and Adler 1989). Wine yeasts produce acetic acid by the oxidation of ac ...
Full Text  - The International Journal of Developmental Biology
Full Text - The International Journal of Developmental Biology

... processes is so intricately complex and precisely regulated that it becomes no wonder that each involves more specific genes and cellular processes than any other function in the plant life cycle. While variability generation - the evolutionary output of the sexual cycle - is the same as in any othe ...
- NRC Research Press
- NRC Research Press

... blocks using a deletion mapping approach. All three chromosomes, 5A, 5B, and 5D, were shown to have a similar structure, apart from the 4A–5A translocation on the distal end of chromosome arm 5AL. The physical mapping of rice markers on the deletion lines revealed that the whole of rice chromosome 9 ...
Hereditary Colorectal Cancer
Hereditary Colorectal Cancer

... HNPCC. It is present in approximately 90% to 95% of cancers in Lynch syndrome, and in approximately 15% of sporadic CRCs. When DNA is amplified using primers derived from highly repetitive DNA sequences, new alleles frequently appear in tumor DNA relative to normal DNA (Fig 18). These new alleles re ...
draft - IC
draft - IC

... Dierent relative weights for the operations have been considered. Proposals have also diered in the number and type of allowed chromosomes (unichromosomal vs. multichromosomal genomes; linear or circular chromosomes). When more than two genomes are considered, we have the more challenging problem ...
pdf file
pdf file

... show that the observed patterns of continuous variation were entirely consistent with Mendelian inheritance. He was also able to consider the effects on these traits of various other modifying factors like dominance, linkage and non-random mating. Moreover, he developed techniques for partitioning t ...
< 1 ... 39 40 41 42 43 44 45 46 47 ... 1937 >

Microevolution

Microevolution is the change in allele frequencies that occur over time within a population. This change is due to four different processes: mutation, selection (natural and artificial), gene flow, and genetic drift. This change happens over a relatively short (in evolutionary terms) amount of time compared to the changes termed 'macroevolution' which is where greater differences in the population occur.Population genetics is the branch of biology that provides the mathematical structure for the study of the process of microevolution. Ecological genetics concerns itself with observing microevolution in the wild. Typically, observable instances of evolution are examples of microevolution; for example, bacterial strains that have antibiotic resistance.Microevolution over time leads to speciation or the appearance of novel structure, sometimes classified as macroevolution. Macro and microevolution describe fundamentally identical processes on different scales.
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