SERIES ‘‘GENETICS OF ASTHMA AND COPD IN THE POSTGENOME ERA’’
... risk factors for asthma but epidemiological studies have revealed that for the disease to develop, additional factors are important [6]. Indeed, in adults and children, atopy [7] or allergen exposure [8] account for substantially ,40% of the population attributable risk for asthma in children or adu ...
... risk factors for asthma but epidemiological studies have revealed that for the disease to develop, additional factors are important [6]. Indeed, in adults and children, atopy [7] or allergen exposure [8] account for substantially ,40% of the population attributable risk for asthma in children or adu ...
INFINITI CYP450 2C19+ Assay
... xenobiotics metabolism. CYP450 2C19 (CYP2C19) is a highly polymorphic liver enzyme of the liver and is involved in the metabolism and elimination of many commonly prescribed drugs including antidepressants, antiepileptics, barbiturates and proton pump inhibitors. Genetic polymorphisms in CYP2C19 are ...
... xenobiotics metabolism. CYP450 2C19 (CYP2C19) is a highly polymorphic liver enzyme of the liver and is involved in the metabolism and elimination of many commonly prescribed drugs including antidepressants, antiepileptics, barbiturates and proton pump inhibitors. Genetic polymorphisms in CYP2C19 are ...
5. Gene350 Animal Genetics 3 August 2009
... – mostly inherited through maternal lineage via egg cytoplasm ...
... – mostly inherited through maternal lineage via egg cytoplasm ...
Two supernumerary marker chromosomes
... Interestingly, in one case reported in the literature two similar familial marker chromosomes lead to very different clinical abnormalities (see Table 2, case 6). These phenotypic differences in a mother and child can only be explained by the higher frequency of one mosaic cell line with an addition ...
... Interestingly, in one case reported in the literature two similar familial marker chromosomes lead to very different clinical abnormalities (see Table 2, case 6). These phenotypic differences in a mother and child can only be explained by the higher frequency of one mosaic cell line with an addition ...
Abstracts - Parthenon Management Group
... the methodological approaches used. The most extensive information available describes the structural and functional impact of risk genes for schizophrenia, bipolar disorder, autism spectrum disorders and neurodegenerative disorders (e.g. Alzheimer’s disease). Initial studies have focused on single ...
... the methodological approaches used. The most extensive information available describes the structural and functional impact of risk genes for schizophrenia, bipolar disorder, autism spectrum disorders and neurodegenerative disorders (e.g. Alzheimer’s disease). Initial studies have focused on single ...
Topology optimization of planar Integrated Lichtwave circuits.
... creating a physical prototype, to assess design risks, and to assist in the discovery of new products by creating the question “what if” product scenarios. But a real dedicated optimization system is not yet been establish. The optimizer part is based on an evolutionary approach. The particularly co ...
... creating a physical prototype, to assess design risks, and to assist in the discovery of new products by creating the question “what if” product scenarios. But a real dedicated optimization system is not yet been establish. The optimizer part is based on an evolutionary approach. The particularly co ...
Simulating Natural Selection
... 1. What was the ratio of lima beans to kidney beans at the start and at the conclusion of the experiment? 2. Based on your data, was on type of bean removed from the bag more frequently than the other? If so, which type? 3. What happened to the frequencies of the lima beans in the population over fi ...
... 1. What was the ratio of lima beans to kidney beans at the start and at the conclusion of the experiment? 2. Based on your data, was on type of bean removed from the bag more frequently than the other? If so, which type? 3. What happened to the frequencies of the lima beans in the population over fi ...
A NEW ALLELE OF THE lpr LOCUS, lpr"9, THAT COMPLEMENTS
... mice maintained at the Laboratory Animal Research Center (10) were used. These strains of mice have not developed lymphadenopathy. MRL/MpJ (MRL-+), MRL/MpJ-lpr/Ipr (MRL-Ipr), C3H/HeJ-Ipr/1pr(C3H-Ipr), and C3H/HeJ-gld/gld (C3H-gld) mice were obtained from The Jackson Laboratory (Bar Harbor, ME), bred ...
... mice maintained at the Laboratory Animal Research Center (10) were used. These strains of mice have not developed lymphadenopathy. MRL/MpJ (MRL-+), MRL/MpJ-lpr/Ipr (MRL-Ipr), C3H/HeJ-Ipr/1pr(C3H-Ipr), and C3H/HeJ-gld/gld (C3H-gld) mice were obtained from The Jackson Laboratory (Bar Harbor, ME), bred ...
Protein export elements from Lactococcus lactis
... extracellular proteins and pharmaceuticals.Although, so far, the natural protein export capacity of lactic acid bacteria has scarcely been studied, these bacteria are known to export several proteins, some of which are secretedinto the growth medium. Thus, lactococci export a cell wall-associatedser ...
... extracellular proteins and pharmaceuticals.Although, so far, the natural protein export capacity of lactic acid bacteria has scarcely been studied, these bacteria are known to export several proteins, some of which are secretedinto the growth medium. Thus, lactococci export a cell wall-associatedser ...
the association of chloroplast dna with photosynthetic membrane
... Further autoradiographs of chloroplast photosynthetic membranes are shown in Figs. 16 and 17 from a separate experiment. The underlying membranes can be seen more readily in these photographs. Fig. 16 is the type of pattern shown in Figs. 1015 where there are peripheral grana rich regions. Fig. 17 s ...
... Further autoradiographs of chloroplast photosynthetic membranes are shown in Figs. 16 and 17 from a separate experiment. The underlying membranes can be seen more readily in these photographs. Fig. 16 is the type of pattern shown in Figs. 1015 where there are peripheral grana rich regions. Fig. 17 s ...
A Single Eubacterial Origin of Eukaryotic
... by PDH from the protomitochondrion (Kerscher and Oesterhelt 1982). However, recent data suggest that all of the eukaryotes which contain PFO also contain genes of mitochondrial origin (Clark and Roger 1995; Bui, Bradley, and Johnson 1996; Germot, Philippe, and Guyader 1996; Horner et al. 1996; Roger ...
... by PDH from the protomitochondrion (Kerscher and Oesterhelt 1982). However, recent data suggest that all of the eukaryotes which contain PFO also contain genes of mitochondrial origin (Clark and Roger 1995; Bui, Bradley, and Johnson 1996; Germot, Philippe, and Guyader 1996; Horner et al. 1996; Roger ...
19p13.3 microdeletions
... Birth weights are known for 12 children and were in the range 1.4kg - 4.1kg (3lb 1oz - 9lb 1oz) with an average birth weight of 2.5kg (5lb 8oz). A number of pregnancies were complicated by a range of problems (10/18). These include oligohydramnios (a low amount of amniotic fluid) (2/18), IUGR (intra ...
... Birth weights are known for 12 children and were in the range 1.4kg - 4.1kg (3lb 1oz - 9lb 1oz) with an average birth weight of 2.5kg (5lb 8oz). A number of pregnancies were complicated by a range of problems (10/18). These include oligohydramnios (a low amount of amniotic fluid) (2/18), IUGR (intra ...
Regulation of the S100B gene by α1-adrenergic - AJP
... payment of page charges. The article must therefore be hereby marked ‘‘advertisement’’ in accordance with 18 U.S.C. Section 1734 solely to indicate this fact. ...
... payment of page charges. The article must therefore be hereby marked ‘‘advertisement’’ in accordance with 18 U.S.C. Section 1734 solely to indicate this fact. ...
South Asian people with diabetes referred for MODY testing have a
... SA people without mutations had higher BMIs than those with confirmed MODY mutations, suggesting that the low MODY detection rate in the SA group is due to a higher prevalence of young-onset, familial diabetes. This likely represents younger-onset type 2 diabetes. The best predictors of MODY in the ...
... SA people without mutations had higher BMIs than those with confirmed MODY mutations, suggesting that the low MODY detection rate in the SA group is due to a higher prevalence of young-onset, familial diabetes. This likely represents younger-onset type 2 diabetes. The best predictors of MODY in the ...
Genetics Terminology Illustrated III Epistasis
... provide the fry with excellent water quality, uncrowded conditions, and feed them well on baby brine shrimp, a lot of them will express the half-black coloration. • If they are overcrowded, underfed, in poor quality water, many may not develop the half-black ...
... provide the fry with excellent water quality, uncrowded conditions, and feed them well on baby brine shrimp, a lot of them will express the half-black coloration. • If they are overcrowded, underfed, in poor quality water, many may not develop the half-black ...
Assessment by Molecular Dynamics Simulations of the Structural
... with the usually accepted consensus for Sp1 binding. In line with this observation are the reports that WT1 binds to (TCC)n tracts19 and that EGR1 can bind with high affinity to sequences such as GAG(T/G)GGGAG, which includes no cytosine in the G-rich strand.20 Therefore, the variability in binding ...
... with the usually accepted consensus for Sp1 binding. In line with this observation are the reports that WT1 binds to (TCC)n tracts19 and that EGR1 can bind with high affinity to sequences such as GAG(T/G)GGGAG, which includes no cytosine in the G-rich strand.20 Therefore, the variability in binding ...
The TP53 Gene, Tobacco Exposure, and Lung Cancer
... a complex interaction between biological factors such as hormonal difference and gendered factors such as smoking behavior [Payne, 2001]. A report from Taiwan found that DNA adduct levels of BPDE (a tobacco carcinogen) in females with lung cancer were markedly greater than those arising in males, su ...
... a complex interaction between biological factors such as hormonal difference and gendered factors such as smoking behavior [Payne, 2001]. A report from Taiwan found that DNA adduct levels of BPDE (a tobacco carcinogen) in females with lung cancer were markedly greater than those arising in males, su ...
Available as a free here - European Cystic Fibrosis Society
... [1,2,6]. It may also be defined either in molecular genetic terms as a disease caused by the presence of two CF-causing mutations one in each parental CFTR gene or in physiological terms as a disorder of electrolyte transport across epithelial membranes resulting from absence or abnormality of the CF ...
... [1,2,6]. It may also be defined either in molecular genetic terms as a disease caused by the presence of two CF-causing mutations one in each parental CFTR gene or in physiological terms as a disorder of electrolyte transport across epithelial membranes resulting from absence or abnormality of the CF ...
Instruction Manual for “ChromoPainter: a copying model for
... instance if you condition a subset of haplotypes (or individuals) on every other haplotype (or individual) using the ’-a’ switch, but is useful for tidying the output files. There should be one row in donor list infile for each donor population. There are 2-4 columns per row. The first column gives ...
... instance if you condition a subset of haplotypes (or individuals) on every other haplotype (or individual) using the ’-a’ switch, but is useful for tidying the output files. There should be one row in donor list infile for each donor population. There are 2-4 columns per row. The first column gives ...
Emended description of the order Chlamydiales, proposal of
... DNA-DNA reassociation, in particular, was established as a tool for distinguishing species (< 70 YO homology) and genera (< 20 YOhomology) (Amann et al., 1995; Schleifer & Stackebrandt, 1983; Wayne et al., 1987). According to these criteria, DNA-DNA reassociation studies of new chlamydial strains an ...
... DNA-DNA reassociation, in particular, was established as a tool for distinguishing species (< 70 YO homology) and genera (< 20 YOhomology) (Amann et al., 1995; Schleifer & Stackebrandt, 1983; Wayne et al., 1987). According to these criteria, DNA-DNA reassociation studies of new chlamydial strains an ...
SNP Discovery and Genotyping Workshop (PowerPoint)
... Warfarin Pharmacogenetics 1. Background • Warfarin characteristics • Pharmacokinetics/Pharmacodynamics • Discovery of VKORC1 2. VKORC1 - SNP Discovery 3. VKORC1 - SNP Selection (tagSNPs) 4. VKORC1 - SNP Testing • SNP/Haplotype Inference • Haplotype Inference, Testing 5. VKORC1 - SNP Replication/Fun ...
... Warfarin Pharmacogenetics 1. Background • Warfarin characteristics • Pharmacokinetics/Pharmacodynamics • Discovery of VKORC1 2. VKORC1 - SNP Discovery 3. VKORC1 - SNP Selection (tagSNPs) 4. VKORC1 - SNP Testing • SNP/Haplotype Inference • Haplotype Inference, Testing 5. VKORC1 - SNP Replication/Fun ...
Characterization of chaperonin 10 (Cpn10)
... mitosome. Here, we report on the identification and structural characterization of a gene encoding the molecular chaperonin Cpn10 – the functional partner of Cpn60 (Hartl, 1996). We find that the upstream region of the gene contains the promoter elements required for transcription in E. histolytica, ...
... mitosome. Here, we report on the identification and structural characterization of a gene encoding the molecular chaperonin Cpn10 – the functional partner of Cpn60 (Hartl, 1996). We find that the upstream region of the gene contains the promoter elements required for transcription in E. histolytica, ...
Evolution of alternative biosynthetic pathways for vitamin C following
... Genomics and evolutionary biology | Plant biology Figure 2. Continued enzyme. Organisms with sequenced genomes that were found to lack both of the terminal enzymes in the known pathways (GULO and GLDH) are likely to be ascorbate auxotrophs and were not included in the plot. These include Giardia in ...
... Genomics and evolutionary biology | Plant biology Figure 2. Continued enzyme. Organisms with sequenced genomes that were found to lack both of the terminal enzymes in the known pathways (GULO and GLDH) are likely to be ascorbate auxotrophs and were not included in the plot. These include Giardia in ...