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Existence Logic - ORION Active Structure
Existence Logic - ORION Active Structure

... We need to be able to talk about and control the existence and nonexistence of objects and relations Objects can be created or destroyed, but sometimes we need to create objects and relations, then “send them dark” - act as though they do not exist and see what that causes - or evaluate a probabilit ...
View/Open
View/Open

... distinct classes. Nilsson-Ehle (1909) and East (1916) were the first to describe quantitative inheritance. They observed that several genes (perhaps 10 or more genes) are involved in the inheritance of a quantitative trait and each gene contributes small and cumulative effect to the total phenotype. ...
Spinal Muscular Atrophy May 2014
Spinal Muscular Atrophy May 2014

... neurons that control muscle movement is thought to contribute to the muscle weakness experienced by people with SMA-LED. It is unclear why this condition affects only the lower extremities. The adult-onset form of spinal muscular atrophy is caused by a mutation in the VAPB gene. The VAPB gene provid ...
Chapter 12
Chapter 12

... 12.1 Basic Patterns of Human Inheritance ...
Gene Section JUN (V-Jun sarcoma virus 17 oncogene homolog (avian))
Gene Section JUN (V-Jun sarcoma virus 17 oncogene homolog (avian))

... JUN is the most important component of AP-1 transcription factors, and its transcriptional activity is possibly attenuated by JUNB or JUND. It has been well accepted that JUN regulates cell proliferation, apoptosis and transformation. JUN promotes cell cycle transition from G1 phase to S phase by up ...
Post-mortem SNP analysis of CYP2D6 gene reveals correlation
Post-mortem SNP analysis of CYP2D6 gene reveals correlation

... Several studies have shown the significance of CYP2D6 polymorphism in clinical settings [20,21]. The corresponding post-mortem literature is scarce. There is one report on a fluoxetine-related death of a child with a deficient CYP2D6 gene detected in the post-mortem investigation [22]. Two other stu ...
pdf View
pdf View

... Fig. 1. The classic and alternative ‘backdoor’ pathways of androgen biosynthesis. The classic pathway proceeds from cholesterol via pregnenolone, 17OH-Preg and DHEA to androstenedione or androstenediol and then to testosterone in testicular Leydig cells (shown in blue). Hormonal testosterone from th ...
Name
Name

... Codominance is when BOTH alleles contribute to the phenotype of the organism. Therefore, in this case a heterozygous phenotype will express both alleles separately and simultaneously. (You will see both alleles in the phenotype.) For example: In shorthorn cattle, red coat color is codominant with wh ...
The Evolution of Ernst: Interview with Ernst Mayr The preeminent
The Evolution of Ernst: Interview with Ernst Mayr The preeminent

... have Avery showing that nucleic acids rather than proteins are the genetic, evolutionary material. And then came Watson-Crick. And then came all the developments in molecular biology and finally the developments in genomics. And each time one of these major upheavals occurred, we expected the theory ...
The TCP domain: a motif found in proteins regulating plant growth
The TCP domain: a motif found in proteins regulating plant growth

... domain found in PCF1 and PCF2, plant DNA-binding proteins that most probably act as transcription factors (Kosugi and Ohashi, 1997). The main conserved features of the TCP domain are: two short stretches of residues in the basic region, hydrophobic residues along the apolar face of both α-helices, a ...
Study of seven single-nucleotide polymorphisms identified in East
Study of seven single-nucleotide polymorphisms identified in East

... risk of chronic diseases, including type 2 diabetes mellitus, cardiovascular diseases, metabolic syndrome and cancer.1 The proposed cut-off points of body mass index (BMI) for obesity are defined differently by Taiwan and the WHO. The Ministry of Health and Welfare in Taiwan has defined obesity as a B ...
Genetics Transcript Q and A with Louise Simard
Genetics Transcript Q and A with Louise Simard

... homozygous for SMN1 mutations. It really is not my place to recommend or not this approach. This is a decision that you will have to make on your own depending on how you feel about the success rates of this technology (and I am not talking about SMA risk here but of implantation) versus getting pre ...
Jeopardy - Mahtomedi Middle School
Jeopardy - Mahtomedi Middle School

... Perry the Platypus met Pinky the Platypus at the park. Perry is homozygous for his teal-green color. Pinky is heterozygous for her pink color. What are the genotypes of the parents? ...
Hidden Markov Models in Bioinformatics
Hidden Markov Models in Bioinformatics

... sequences. With so many genomes being sequenced so rapidly, it remains important to begin by identifying genes computationally. ...
Jeopardy - Mahtomedi Middle School
Jeopardy - Mahtomedi Middle School

... Perry the Platypus met Pinky the Platypus at the park. Perry is homozygous for his teal-green color. Pinky is heterozygous for her pink color. What are the genotypes of the parents? ...
Package `GOFunction`
Package `GOFunction`

... folder. This table contains seven columns: goid, name, refnum (the number of the reference genes in a GO term), interestnum (the number of the interesting genes in a GO term), pvalue, adjustp (the corrected p value by the fdr control), FinalResults. The "FinalResults" contains three types: (1) "Loca ...
Loss of heterozygosity (LOH) at 17q and 14q in human lung
Loss of heterozygosity (LOH) at 17q and 14q in human lung

... this tumor suppressor locus would be expected to represent a substantial advance in the ®eld of cancer molecular genetics. Although these regions are not small enough to plausibly indicate a positional cloning e€ort, it is possible to narrow down the minimal regions of deletion through the identi®ca ...
Unit 6 Lesson 4
Unit 6 Lesson 4

... What did Gregor Mendel discover about heredity? • Mendel hypothesized that each plant must have two heritable “factors” for each trait, one from each parent. • Some traits, such as yellow color, could only be observed if a plant had two of the same factors. ...
Evolution of DNA Sequencing - Journal of the College of Physicians
Evolution of DNA Sequencing - Journal of the College of Physicians

... discrimination between fragment sizes during electrophoresis. Secondly, the analysis of highly polymorphic regions such as Major Histocompatibility Complex (MHC) which is the most polymorphic gene known,17 could generate complex data due to multiple heterozygous positions in the sequence. Thirdly, D ...
Supplementary Information (doc 408K)
Supplementary Information (doc 408K)

... fulfilling the DSM-IV criteria of schizophrenia for proband recruitment based on clinical observation and interview by the attending psychiatrist providing the psychiatric services. (2) After identifying the potential proband, the parents were informed about the details of this study, and initial o ...
Quiz Show
Quiz Show

... Question: What principle states that during gamete formation genes for different traits separate without influencing each other’s inheritance. a. principle of independent assortment b. principle of dominance c. principle of prohibition ...
Chapter 9 PowerPoint
Chapter 9 PowerPoint

...  Flower position along stem (axial and terminal)  Pod color (green and yellow)  Pod appearance (inflated and constricted)  Seed texture (round and wrinkled)  Seed color (yellow and green0  Flower color (purple and white) ...
A/a · B/b
A/a · B/b

... intermediate that is then modified by the product of the B gene. If the plant is a/a, this intermediate is not made and the phenotype of the plant is the same regardless of the ability to produce functional B product. ...
Varieties of Mugineic Acid Family Phytosiderophores Secreted from
Varieties of Mugineic Acid Family Phytosiderophores Secreted from

... Graminaceous plants utilize mugineic acid family phytosiderophores (MAs) in Fe acquisition from the soils and Fe translocation inside the body. Furthermore, MAs are significant for seed maturation as well as Fe homeostasis in graminaceous plants. Foxtail millet (Setaria italica) is the second-most w ...
Name ________ SEX - LINKED Practice Problems A female has the
Name ________ SEX - LINKED Practice Problems A female has the

... a carrier is a female that carries one copy of the sex-linked allele, but does not have the disease.) _______ What is the probability of getting offspring that are blue-eyed? _______ What is the probability of getting offspring that are blue-eyed colorblind males? _______ What is the probability of ...
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Microevolution

Microevolution is the change in allele frequencies that occur over time within a population. This change is due to four different processes: mutation, selection (natural and artificial), gene flow, and genetic drift. This change happens over a relatively short (in evolutionary terms) amount of time compared to the changes termed 'macroevolution' which is where greater differences in the population occur.Population genetics is the branch of biology that provides the mathematical structure for the study of the process of microevolution. Ecological genetics concerns itself with observing microevolution in the wild. Typically, observable instances of evolution are examples of microevolution; for example, bacterial strains that have antibiotic resistance.Microevolution over time leads to speciation or the appearance of novel structure, sometimes classified as macroevolution. Macro and microevolution describe fundamentally identical processes on different scales.
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