Article (Published version)
... classification. For example, neonatal diabetes is diagnosed within 6 months of birth, whereas MODY forms of diabetes occur before the age of 25 years. However, recent studies report Received 16 December 2013; accepted 17 December 2013 ...
... classification. For example, neonatal diabetes is diagnosed within 6 months of birth, whereas MODY forms of diabetes occur before the age of 25 years. However, recent studies report Received 16 December 2013; accepted 17 December 2013 ...
Novel pathogen-specific primers for the detection of Agrobacterium
... limits the efficiency of PCR. For example, the virC-specific primers amplify the corresponding sequences from A. tumefaciens (SAWADA et al. 1995), but not from A. vitis (SZEGEDI and BOTTKA, 2002). Although an improved virCspecific primer pair detected some A. vitis strains (KAWAGUCHI et al. 2005), comp ...
... limits the efficiency of PCR. For example, the virC-specific primers amplify the corresponding sequences from A. tumefaciens (SAWADA et al. 1995), but not from A. vitis (SZEGEDI and BOTTKA, 2002). Although an improved virCspecific primer pair detected some A. vitis strains (KAWAGUCHI et al. 2005), comp ...
Scriver Charles R. Garrod`s Croonian Lectures (1908)
... Meanwhile, in medicine, the apparent rarity of the inborn errors of metabolism made them irrelevant to the medical profession and efforts to show their inheritance and congenital nature were of little help to the practice of medicine in Garrod_s lifetime. Moreover, the opinion that these disorders w ...
... Meanwhile, in medicine, the apparent rarity of the inborn errors of metabolism made them irrelevant to the medical profession and efforts to show their inheritance and congenital nature were of little help to the practice of medicine in Garrod_s lifetime. Moreover, the opinion that these disorders w ...
Gregor Mendel was a 19th century priest and botanist who
... monohybrid experiment as A + 2Aa + a, instead of AA + 2Aa + aa. Mendel may have concluded that like elements (alleles) do not pair with one another and do not segregate in plants that are not hybrids (i.e., are not heterozygotes), and that therefore a single letter was an accurate way to represent s ...
... monohybrid experiment as A + 2Aa + a, instead of AA + 2Aa + aa. Mendel may have concluded that like elements (alleles) do not pair with one another and do not segregate in plants that are not hybrids (i.e., are not heterozygotes), and that therefore a single letter was an accurate way to represent s ...
The genetics of Caenorhabditis elegans.
... and the ovary is manufacturing eggs. Any mutation produced in such an animal will Rot appear in the homozygous form in the progeny because there are no cells at this stage that can give rise to both sperm and eggs. If the mutagen acted only on non-replicating gametes, such as sperm or oocytes, then ...
... and the ovary is manufacturing eggs. Any mutation produced in such an animal will Rot appear in the homozygous form in the progeny because there are no cells at this stage that can give rise to both sperm and eggs. If the mutagen acted only on non-replicating gametes, such as sperm or oocytes, then ...
Simple Algorithms to Calculate Asymptotic Null Distributions of
... contingency table. Under the alternative hypothesis, if one of the two alleles confers a high risk of the disease, an individual’s risk having the disease increases with the number of risk alleles in the genotype. In other words, the alternative is ordered or penetrances are ordered, where a penetra ...
... contingency table. Under the alternative hypothesis, if one of the two alleles confers a high risk of the disease, an individual’s risk having the disease increases with the number of risk alleles in the genotype. In other words, the alternative is ordered or penetrances are ordered, where a penetra ...
Protocol: Genome-scale CRISPR-Cas9 Knockout
... considerations for setting the relevant screening parameters as well as technical advice for carrying out a screen in Box 2. Additional in vivo screening considerations are described in Box 3. We also provide guidelines for saturated mutagenesis screening design and analysis in Box 4. Analysis of sc ...
... considerations for setting the relevant screening parameters as well as technical advice for carrying out a screen in Box 2. Additional in vivo screening considerations are described in Box 3. We also provide guidelines for saturated mutagenesis screening design and analysis in Box 4. Analysis of sc ...
Protocol: Genome-scale CRISPR-Cas9 Knockout
... considerations for setting the relevant screening parameters as well as technical advice for carrying out a screen in Box 2. Additional in vivo screening considerations are described in Box 3. We also provide guidelines for saturated mutagenesis screening design and analysis in Box 4. Analysis of sc ...
... considerations for setting the relevant screening parameters as well as technical advice for carrying out a screen in Box 2. Additional in vivo screening considerations are described in Box 3. We also provide guidelines for saturated mutagenesis screening design and analysis in Box 4. Analysis of sc ...
clinical dilemmas and surgical treatment of penoscrotal, scrotal and
... some Y considered responsible for the spermatogenesis. At the short arm of the chromosomes X and Y there are homologous sites that approach each other during the zygonema of the myosis. This means that the genetic material is exchanged between X and Y chromosomes during the cross-over process. Since ...
... some Y considered responsible for the spermatogenesis. At the short arm of the chromosomes X and Y there are homologous sites that approach each other during the zygonema of the myosis. This means that the genetic material is exchanged between X and Y chromosomes during the cross-over process. Since ...
conte et al 2015 genetics - UBC Zoology
... (Conte et al. 2012). However, caution is warranted when interpreting estimates based on both approaches. Candidate gene studies of repeated phenotypic evolution are prone to publication bias and have focused mainly on a small number of genes with mostly unknown effect sizes. Mapping studies of repe ...
... (Conte et al. 2012). However, caution is warranted when interpreting estimates based on both approaches. Candidate gene studies of repeated phenotypic evolution are prone to publication bias and have focused mainly on a small number of genes with mostly unknown effect sizes. Mapping studies of repe ...
Section 1 The application - Office of the Gene Technology Regulator
... must follow when considering an application for a licence to intentionally release a genetically modified organism (GMO) into the environment. For a licence to be issued, the Regulator must be satisfied that the release will not pose any risks to human health and safety and the environment that can ...
... must follow when considering an application for a licence to intentionally release a genetically modified organism (GMO) into the environment. For a licence to be issued, the Regulator must be satisfied that the release will not pose any risks to human health and safety and the environment that can ...
MATE CHOICE FOR OPTIMAL (K)INBREEDING
... agreement with the prediction that intermediately related individuals should be preferred as reproductive partners. Inbreeding depression (b) on fitness components has been estimated to range between 0.55 and 0.82 in the wild (Crnokrak and Roff 1999). As inbreeding depression for total fitness is pr ...
... agreement with the prediction that intermediately related individuals should be preferred as reproductive partners. Inbreeding depression (b) on fitness components has been estimated to range between 0.55 and 0.82 in the wild (Crnokrak and Roff 1999). As inbreeding depression for total fitness is pr ...
StanfordEncyclopedia_2016_Inheritance
... be seen as not involving a distinct inheritance system, if this notion is understood to refer to the way hereditary information is stored and transmitted. Indeed, views that focus on multiple inheritance systems, may for the same reason not consider the inheritance of plastids as based on a distinct ...
... be seen as not involving a distinct inheritance system, if this notion is understood to refer to the way hereditary information is stored and transmitted. Indeed, views that focus on multiple inheritance systems, may for the same reason not consider the inheritance of plastids as based on a distinct ...
Application of whole genome sequencing to fully characterise
... Campylobacter is the most common cause of acute bacterial gastroenteritis worldwide. In the UK alone it causes an estimated 500,000 infections each year. There have been two large studies of Infectious Intestinal Disease in the UK community (IID1 in the mid 1990s and IID2 in 2008-2009). In both stud ...
... Campylobacter is the most common cause of acute bacterial gastroenteritis worldwide. In the UK alone it causes an estimated 500,000 infections each year. There have been two large studies of Infectious Intestinal Disease in the UK community (IID1 in the mid 1990s and IID2 in 2008-2009). In both stud ...
BAM Receptors Regulate Stem Cell Specification and Organ
... mutations: Our previous genetic studies have suggested that BAM and CLV1 proteins have retained significant biochemical redundancy, although the developmental role of BAM1 and BAM2 is apparently antagonistic to that of CLV1 in the meristem (DeYoung et al. 2006). We therefore undertook experiments to ...
... mutations: Our previous genetic studies have suggested that BAM and CLV1 proteins have retained significant biochemical redundancy, although the developmental role of BAM1 and BAM2 is apparently antagonistic to that of CLV1 in the meristem (DeYoung et al. 2006). We therefore undertook experiments to ...
Ch 5 Review Glencoe Power Pt
... • Gene therapy shows promise for correcting many human genetic disorders by inserting normal alleles into cells. To return to the chapter summary click Escape or close this document. ...
... • Gene therapy shows promise for correcting many human genetic disorders by inserting normal alleles into cells. To return to the chapter summary click Escape or close this document. ...
Chapter 7- Ecology of Phenotypic Plasticity
... daily behavioral change of the spider is similar to many behavioral changes that occur in other animals between day and night. Are all of these changes examples of plasticity? If so, are they really 'equivalent to heterophylly' in plants? DeWitt: 1) I have to take issue with at least two of DeWitt's ...
... daily behavioral change of the spider is similar to many behavioral changes that occur in other animals between day and night. Are all of these changes examples of plasticity? If so, are they really 'equivalent to heterophylly' in plants? DeWitt: 1) I have to take issue with at least two of DeWitt's ...
Analysis of expressed sequence tags from the Huperzia serrata leaf
... However, as of January 2009, there were only 10 nucleotide sequences from H . serrata available in the NCBI database. The limited information on the genetic contents of this plant triggered our efforts to construct a cDNA library from the H . serrata leaf. The objective of this study was to identify ...
... However, as of January 2009, there were only 10 nucleotide sequences from H . serrata available in the NCBI database. The limited information on the genetic contents of this plant triggered our efforts to construct a cDNA library from the H . serrata leaf. The objective of this study was to identify ...
TRIPTYCHON and CAPRICE mediate lateral inhibition during
... epidermis, although this particular ®nding was interpreted as an unspeci®c competition with the trichome-promoting factor GL1 (Wada et al., 1997). In this work, we report the positional cloning and molecular characterization of the TRY gene. TRY encodes a MYB-related protein with high sequence simil ...
... epidermis, although this particular ®nding was interpreted as an unspeci®c competition with the trichome-promoting factor GL1 (Wada et al., 1997). In this work, we report the positional cloning and molecular characterization of the TRY gene. TRY encodes a MYB-related protein with high sequence simil ...
Wildlife Crime - TRACE Wildlife Forensics Network
... This guide aims to be a handbook that will inform enforcement officers involved in wildlife crime investigation about specialist forensic techniques. Whilst the guide is written from the perspective of law enforcement in the UK, many of the described techniques will be applicable to wildlife crime i ...
... This guide aims to be a handbook that will inform enforcement officers involved in wildlife crime investigation about specialist forensic techniques. Whilst the guide is written from the perspective of law enforcement in the UK, many of the described techniques will be applicable to wildlife crime i ...
Hox patterning of the vertebrate rib cage
... paralogous groups based on sequence similarity and position within the cluster. Hox expression along the vertebrate AP axis exhibits overlapping expression domains with unique and increasingly posterior limits of expression (Colberg-Poley et al., 1985; Duboule and Dolle, 1989; Izpisua-Belmonte et al ...
... paralogous groups based on sequence similarity and position within the cluster. Hox expression along the vertebrate AP axis exhibits overlapping expression domains with unique and increasingly posterior limits of expression (Colberg-Poley et al., 1985; Duboule and Dolle, 1989; Izpisua-Belmonte et al ...
ARTICLES - Weizmann Institute of Science
... Eran Segal1, Yvonne Fondufe-Mittendorf2, Lingyi Chen2, AnnChristine Thåström2, Yair Field1, Irene K. Moore2, Ji-Ping Z. Wang3 & Jonathan Widom2 Eukaryotic genomes are packaged into nucleosome particles that occlude the DNA from interacting with most DNA binding proteins. Nucleosomes have higher af ...
... Eran Segal1, Yvonne Fondufe-Mittendorf2, Lingyi Chen2, AnnChristine Thåström2, Yair Field1, Irene K. Moore2, Ji-Ping Z. Wang3 & Jonathan Widom2 Eukaryotic genomes are packaged into nucleosome particles that occlude the DNA from interacting with most DNA binding proteins. Nucleosomes have higher af ...
Real time PCR and it`s role in diagnosis
... Cystic fibrosis Cystic fibrosis (CF) is the most common inherited disease among Caucasian populations with an incidence of ~1 in 2500 births.(9) Couples in which both individuals carry a mutant copy of the CF gene have a one in four chance of having an affected child.The conditions caused by these ...
... Cystic fibrosis Cystic fibrosis (CF) is the most common inherited disease among Caucasian populations with an incidence of ~1 in 2500 births.(9) Couples in which both individuals carry a mutant copy of the CF gene have a one in four chance of having an affected child.The conditions caused by these ...
Hox patterning of the vertebrate rib cage
... paralogous groups based on sequence similarity and position within the cluster. Hox expression along the vertebrate AP axis exhibits overlapping expression domains with unique and increasingly posterior limits of expression (Colberg-Poley et al., 1985; Duboule and Dolle, 1989; Izpisua-Belmonte et al ...
... paralogous groups based on sequence similarity and position within the cluster. Hox expression along the vertebrate AP axis exhibits overlapping expression domains with unique and increasingly posterior limits of expression (Colberg-Poley et al., 1985; Duboule and Dolle, 1989; Izpisua-Belmonte et al ...