Chromosomal breakpoint positions suggest a direct role for radiation
... (Santoro et al., 1993). However, malignant phenotype was obtained by cotransfection with H-RAS or K-RAS oncogenes. An alternative to the direct pathway is that radiation does not act directly to produce the RET/PTC3 fusion, but instead may cause persistent genomic instability, which eventually produ ...
... (Santoro et al., 1993). However, malignant phenotype was obtained by cotransfection with H-RAS or K-RAS oncogenes. An alternative to the direct pathway is that radiation does not act directly to produce the RET/PTC3 fusion, but instead may cause persistent genomic instability, which eventually produ ...
Genetic, psychosocial, and demographic factors associated with
... indicators of behavioral disinhibition: nicotine, alcohol consumption, alcohol dependence, illicit drugs, and nonsubstance-related behavioral disinhibition. This study found only one SNP (rs1868152) that attained genomewide significance (P = 5 9 10 8), for the indicator of illicit drug use, but auth ...
... indicators of behavioral disinhibition: nicotine, alcohol consumption, alcohol dependence, illicit drugs, and nonsubstance-related behavioral disinhibition. This study found only one SNP (rs1868152) that attained genomewide significance (P = 5 9 10 8), for the indicator of illicit drug use, but auth ...
asdfs - Neshaminy School District
... a. Could this trait be inherited as a simple autosomal recessive? b. Could this trait be inherited as a simple autosomal dominant? c. Could this trait be inherited as a simple x linked recessive? d. Could this trait be inherited as a simple x linked dominant? ...
... a. Could this trait be inherited as a simple autosomal recessive? b. Could this trait be inherited as a simple autosomal dominant? c. Could this trait be inherited as a simple x linked recessive? d. Could this trait be inherited as a simple x linked dominant? ...
Mendelian error detection in complex pedigree using weighted
... a probability distribution on stochastic variables. To model errors, a usual approach is to distinguish the observation O and the truth T . A CPT P (O|T ) relates the two variables and models the probability of error. Following this, we consider the following model for error correction: we first hav ...
... a probability distribution on stochastic variables. To model errors, a usual approach is to distinguish the observation O and the truth T . A CPT P (O|T ) relates the two variables and models the probability of error. Following this, we consider the following model for error correction: we first hav ...
Is HARLAN`S HAWK a subspecies of Red
... hybridization. If the resulting gene flow were unrestricted, then one would expect that both forms would share traits and look much more alike, most likely with a hybrid zone between their breeding ranges. Clearly this isn’t happening. Something is causing the majority of Harlan’s to be dark and the ...
... hybridization. If the resulting gene flow were unrestricted, then one would expect that both forms would share traits and look much more alike, most likely with a hybrid zone between their breeding ranges. Clearly this isn’t happening. Something is causing the majority of Harlan’s to be dark and the ...
Genetic Mosaics and the Germ Line Lineage
... Abstract: Genetic mosaics provide information about cellular lineages that is otherwise difficult to obtain, especially in humans. De novo mutations act as cell markers, allowing the tracing of developmental trajectories of all descendants of the cell in which the new mutation arises. De novo mutati ...
... Abstract: Genetic mosaics provide information about cellular lineages that is otherwise difficult to obtain, especially in humans. De novo mutations act as cell markers, allowing the tracing of developmental trajectories of all descendants of the cell in which the new mutation arises. De novo mutati ...
Reproduction of Earthworms: Sexual Selection and
... Aside from size, reciprocation is sought from a potential partner. In simultaneous hermaphrodites, the primary purpose of mating is to fertilize the eggs of their partners, rather than to fertilize their own eggs. Therefore, the conflict of two earthworms copulating would be the amount of sperm that ...
... Aside from size, reciprocation is sought from a potential partner. In simultaneous hermaphrodites, the primary purpose of mating is to fertilize the eggs of their partners, rather than to fertilize their own eggs. Therefore, the conflict of two earthworms copulating would be the amount of sperm that ...
Structure of B-DNA with Cations Tethered in the Major Groove†
... (Z3dU, Figure 1). The four n-propyl-amino groups of DDD4+ are protonated under the conditions of our experiments. The 4+ of DDD4+ represents the charge of the four modifications. The net charge of the DDD4+, including contributions from phosphate groups, is 18-. The goal of the work here is to deter ...
... (Z3dU, Figure 1). The four n-propyl-amino groups of DDD4+ are protonated under the conditions of our experiments. The 4+ of DDD4+ represents the charge of the four modifications. The net charge of the DDD4+, including contributions from phosphate groups, is 18-. The goal of the work here is to deter ...
Evaluation of genomic DNA from paraffin
... All genomes consist of genetic polymorphism, which are sequences that are found in two or more variants (alleles) within a population. If the variants persist in the population with allele frequencies above 1 % for the rarest allele it is called a genetic polymorphism. Single nucleotide polymorphism ...
... All genomes consist of genetic polymorphism, which are sequences that are found in two or more variants (alleles) within a population. If the variants persist in the population with allele frequencies above 1 % for the rarest allele it is called a genetic polymorphism. Single nucleotide polymorphism ...
Effective Clustering Algorithms for Gene Expression Data
... based on their expression patterns of gene. Clustering can be performed based on genes and samples. In gene based clustering, the genes are treated as the objects, while the samples are the features. In sample based clustering, the samples can be partitioned into homogeneous groups where the genes a ...
... based on their expression patterns of gene. Clustering can be performed based on genes and samples. In gene based clustering, the genes are treated as the objects, while the samples are the features. In sample based clustering, the samples can be partitioned into homogeneous groups where the genes a ...
Course Objectives
... 4. Compare the structure of prokaryotic and eukaryotic chromosomes. 5. Describe the stages and significance of the cell cycle. 6. List the phases of mitosis and describe the events characteristic of each phase. Recognize the phases of mitosis in diagrams and micrographs. 7. Compare cytokinesis in an ...
... 4. Compare the structure of prokaryotic and eukaryotic chromosomes. 5. Describe the stages and significance of the cell cycle. 6. List the phases of mitosis and describe the events characteristic of each phase. Recognize the phases of mitosis in diagrams and micrographs. 7. Compare cytokinesis in an ...
Conspiracy of silence among repeated transgenes
... conjecture might be correct. When vertebrates are transformed with exogenous DNA, chromosomal insertions almost always consist of long tandem arrays of the transfected transgene-containing DNA.(5) Sometimes transgene arrays can comprise hundreds or even thousands of copies. In a cytologic study of o ...
... conjecture might be correct. When vertebrates are transformed with exogenous DNA, chromosomal insertions almost always consist of long tandem arrays of the transfected transgene-containing DNA.(5) Sometimes transgene arrays can comprise hundreds or even thousands of copies. In a cytologic study of o ...
multicopy gene family evolution on primate y chromosomes
... Contrary to previous theories, the Y chromosome is an important determinant of male phenotype [15–17]. The Y chromosome has been found to be associated with male fertility in humans [18] and even less obvious traits like lifespan [19] and locomotive activity [20] in Drosophila species. Therefore, an ...
... Contrary to previous theories, the Y chromosome is an important determinant of male phenotype [15–17]. The Y chromosome has been found to be associated with male fertility in humans [18] and even less obvious traits like lifespan [19] and locomotive activity [20] in Drosophila species. Therefore, an ...
pedigree_worksheet_1-16
... Sex-linked dominant: Gene is located on the X-chromosome. Need only one dominant allele to have the disorder/trait (A_). All daughters of an affected male will be affected since the father has only the defective allele to give. Sex-linked recessive: Gene is located on the X-chromosome. Need two copi ...
... Sex-linked dominant: Gene is located on the X-chromosome. Need only one dominant allele to have the disorder/trait (A_). All daughters of an affected male will be affected since the father has only the defective allele to give. Sex-linked recessive: Gene is located on the X-chromosome. Need two copi ...
Journal of Bacteriology
... phenotypic switching that is mediated by mutation, reorganization, or modification of DNA. This process is used by several bacterial species to generate population diversity that increases bacterial fitness and is important in niche adaptation (33). Phase variation can sometimes be observed by the a ...
... phenotypic switching that is mediated by mutation, reorganization, or modification of DNA. This process is used by several bacterial species to generate population diversity that increases bacterial fitness and is important in niche adaptation (33). Phase variation can sometimes be observed by the a ...
1. Project summary
... cytoplasm, Contractor 2 recently showed evidence that spastin is also a nuclear protein. ...
... cytoplasm, Contractor 2 recently showed evidence that spastin is also a nuclear protein. ...
Temperature-sensitive control of protein activity by conditionally
... characterized inteins, Sce VMA. We established a system in which growth of a Gal4 mutant S. cerevisiae strain FY760 (ref. 9) on a galactose carbon source was dependent on rescue by a plasmid constitutively expressing Gal4. Although the splicing of inteins is entirely autonomous, the host protein res ...
... characterized inteins, Sce VMA. We established a system in which growth of a Gal4 mutant S. cerevisiae strain FY760 (ref. 9) on a galactose carbon source was dependent on rescue by a plasmid constitutively expressing Gal4. Although the splicing of inteins is entirely autonomous, the host protein res ...
2006 - HMS - Harvard University
... has been at the University of California, San Francisco, where she has been the Herbert Boyer Distinguished Professor of Biochemistry and Biophysics, and is now an American Cancer Society Professor. Kenyon’s early studies contributed to the remarkable discovery that patterns of body structures are g ...
... has been at the University of California, San Francisco, where she has been the Herbert Boyer Distinguished Professor of Biochemistry and Biophysics, and is now an American Cancer Society Professor. Kenyon’s early studies contributed to the remarkable discovery that patterns of body structures are g ...
emboj201385-sup
... represents 50μm. (I) A significant increase in ISL1+ neurons was observed in Hmx1fl/fl;Wnt1-Cre compared to WT SG at P0. n=3 animals/group, 14-44 ganglia were analyzed per animal. Statistical analysis was performed using Student’s t-test. * p < 0.05. (J) Double immunostaining for ISL1 and NPY, ChAT, ...
... represents 50μm. (I) A significant increase in ISL1+ neurons was observed in Hmx1fl/fl;Wnt1-Cre compared to WT SG at P0. n=3 animals/group, 14-44 ganglia were analyzed per animal. Statistical analysis was performed using Student’s t-test. * p < 0.05. (J) Double immunostaining for ISL1 and NPY, ChAT, ...
Jean Deutsch
... independent vectors operating during the life time of an organism. To do this, we set up a semicircular clock with two hands. One hand represents our best statistic for a measure of size. […] The other hand measures shape, which may be disconnected from its ancestral relationship to size during evol ...
... independent vectors operating during the life time of an organism. To do this, we set up a semicircular clock with two hands. One hand represents our best statistic for a measure of size. […] The other hand measures shape, which may be disconnected from its ancestral relationship to size during evol ...
PDF
... ,A~} f'xaminnlion of til!:' vnlues given in tnbln 1 shows that tho mean of E\ is not signifiC'll1ltly cliff('I't'ut fl'om the average of menns of thr t.wo pn.rcufs lll1d that tIl(' meun of Br to PorlcI' is not significuntly difl'f'rt'nt ft'om lhe t'wcl'nge of means of 1i\ nnd Porter. This indicntes ...
... ,A~} f'xaminnlion of til!:' vnlues given in tnbln 1 shows that tho mean of E\ is not signifiC'll1ltly cliff('I't'ut fl'om the average of menns of thr t.wo pn.rcufs lll1d that tIl(' meun of Br to PorlcI' is not significuntly difl'f'rt'nt ft'om lhe t'wcl'nge of means of 1i\ nnd Porter. This indicntes ...
Determining the Relationship between Phlyctimantis and Kassina
... breeding seasons. The female follows the voice until hopefully she finds her mate. Because of this, mating calls are species-specific. Frogs, therefore, want to have the most dissimilar call as possible to avoid any competition – especially in the tropics where tons of frogs are calling at once. It ...
... breeding seasons. The female follows the voice until hopefully she finds her mate. Because of this, mating calls are species-specific. Frogs, therefore, want to have the most dissimilar call as possible to avoid any competition – especially in the tropics where tons of frogs are calling at once. It ...