Androgen insensitivity syndrome
... mosaicism in the gonads of one of the parents, or a mutation in the fertilized egg itself.[45] In one study,[46] it was found that 3 out of 8 de novo mutations occurred in the postzygotic stage, leading to the estimate that up to one third of de novo mutations result in somatic mosaicism.[1] It is w ...
... mosaicism in the gonads of one of the parents, or a mutation in the fertilized egg itself.[45] In one study,[46] it was found that 3 out of 8 de novo mutations occurred in the postzygotic stage, leading to the estimate that up to one third of de novo mutations result in somatic mosaicism.[1] It is w ...
Translocation Breakpoints Are Clustered on Both Chromosome 8
... By using a probe synthesized on the basis of the published cDNA sequence, clones were isolated from a human genomic library spanning most of the intron centromeric to the fifth reported AMLl exon.7 This is the region where chromosome 21 breakpoints were suggested to cluster in the t(8;21). As the in ...
... By using a probe synthesized on the basis of the published cDNA sequence, clones were isolated from a human genomic library spanning most of the intron centromeric to the fifth reported AMLl exon.7 This is the region where chromosome 21 breakpoints were suggested to cluster in the t(8;21). As the in ...
Bacterial evolution and the cost of antibiotic resistance
... hosts with both the ancestral and evolved plasmids, giving four genotypes: B0/P0, B0/P500, B500/P0, and B500/P500, where B and P denote the bacteria and plasmid, respectively, and subscripts 0 and 500 indicate the ancestral (naive) and evolved forms, respectively. Each of these genotypes was placed ...
... hosts with both the ancestral and evolved plasmids, giving four genotypes: B0/P0, B0/P500, B500/P0, and B500/P500, where B and P denote the bacteria and plasmid, respectively, and subscripts 0 and 500 indicate the ancestral (naive) and evolved forms, respectively. Each of these genotypes was placed ...
Fulltext PDF - Indian Academy of Sciences
... earliness by vernalization. Johanson et al (2000) have recently cloned FRI and analysed the molecular basis of the allelic variation. Most early-flowering ecotypes carry FRI alleles that contain one of two different deletions that disrupt the open reading frame of the FRI gene. This suggests that lo ...
... earliness by vernalization. Johanson et al (2000) have recently cloned FRI and analysed the molecular basis of the allelic variation. Most early-flowering ecotypes carry FRI alleles that contain one of two different deletions that disrupt the open reading frame of the FRI gene. This suggests that lo ...
CtrA mediates a DNA replication checkpoint that prevents cell
... control, phosphorylation and proteolysis (Domian et al., 1997, 1999; Quon et al., 1998). CtrA-P is present in swarmer cells and is degraded during swarmer to stalked cell differentiation by the ClpXP protease (Jenal and Fuchs, 1998). ctrA transcription is regulated by the opposite action of CtrA on ...
... control, phosphorylation and proteolysis (Domian et al., 1997, 1999; Quon et al., 1998). CtrA-P is present in swarmer cells and is degraded during swarmer to stalked cell differentiation by the ClpXP protease (Jenal and Fuchs, 1998). ctrA transcription is regulated by the opposite action of CtrA on ...
Supplementary Information (doc 1628K)
... primeview assay for target synthesis and labeling. Samples were hybridized to the Genechip primeview human gene expression array and those demonstrating a cutoff greater or less than 1.5-fold difference from the parental cell line used for further analysis. The quality of the total RNA was confirmed ...
... primeview assay for target synthesis and labeling. Samples were hybridized to the Genechip primeview human gene expression array and those demonstrating a cutoff greater or less than 1.5-fold difference from the parental cell line used for further analysis. The quality of the total RNA was confirmed ...
Phylogenetic analysis of members of the genus Rickettsia using the
... spotted fever. Integration of phenotypic, genotypic and phylogenetic data will contribute to the definition of a polyphasic taxonomy as has been done for other bacterial genera. ...
... spotted fever. Integration of phenotypic, genotypic and phylogenetic data will contribute to the definition of a polyphasic taxonomy as has been done for other bacterial genera. ...
Dynamic Changes in Aromatic Hydrocarbon Associated Catabolic
... Aerobic pathways of aromatic hydrocarbon degradation employ oxygen as a terminal electron acceptor, and mono- and dioxygenase enzymes, to cleave the benzene ring which results in a loss of aromaticity [4]. Biodegradation pathways of aromatic hydrocarbons have been intensively investigated, much is k ...
... Aerobic pathways of aromatic hydrocarbon degradation employ oxygen as a terminal electron acceptor, and mono- and dioxygenase enzymes, to cleave the benzene ring which results in a loss of aromaticity [4]. Biodegradation pathways of aromatic hydrocarbons have been intensively investigated, much is k ...
Monohybrid and Dihybrid Crosses
... In this lesson, you will learn how to predict the probable genetic makeup and appearance of offspring resulting from specific crosses.! ...
... In this lesson, you will learn how to predict the probable genetic makeup and appearance of offspring resulting from specific crosses.! ...
Tissue- and Development-specific Expression of Multiple
... Isolation of multiple nNOS transcripts with unique 59UTRs. Cloning and sequencing of cDNA by RACE from brain, kidney, heart, intestine, and embryo led to the identification of three different nNOS mRNA species that are designated as nNOSa, nNOSb, and nNOSc. nNOSa was overall the most abundant isofor ...
... Isolation of multiple nNOS transcripts with unique 59UTRs. Cloning and sequencing of cDNA by RACE from brain, kidney, heart, intestine, and embryo led to the identification of three different nNOS mRNA species that are designated as nNOSa, nNOSb, and nNOSc. nNOSa was overall the most abundant isofor ...
Patterns of Inheritance 20102011
... IA, IB, and i, but an individual has only two at a time. 2. The sickle cell allele, s, is responsible for a variety of phenotypic effects, from pain and fever to damage to the heart, lungs, joints, brain or kidneys. 3. If a red shorthorn cow is mated with a white bull, all their offspring are roan, ...
... IA, IB, and i, but an individual has only two at a time. 2. The sickle cell allele, s, is responsible for a variety of phenotypic effects, from pain and fever to damage to the heart, lungs, joints, brain or kidneys. 3. If a red shorthorn cow is mated with a white bull, all their offspring are roan, ...
Overextension: The Extended Mind and Arguments from
... so, as it is not even clear how one would begin to make the case for EMT2 using the EPT: the latter is a thesis about which of the many effects of a gene evolutionary biologists should consider its phenotype, the former is a thesis about what kind of entity cognitive scientists should study. The fac ...
... so, as it is not even clear how one would begin to make the case for EMT2 using the EPT: the latter is a thesis about which of the many effects of a gene evolutionary biologists should consider its phenotype, the former is a thesis about what kind of entity cognitive scientists should study. The fac ...
International Journal of Soft Computing and Engineering (IJSCE)
... Crossover operators are the backbone of the genetic algorithm. Reproduction makes clones of good strings but does not create new ones. Crossover operators are applied to mating pool with hope that it creates a better offspring. Partially Matched or Mapped Crossover (PMX) is the most widely used cros ...
... Crossover operators are the backbone of the genetic algorithm. Reproduction makes clones of good strings but does not create new ones. Crossover operators are applied to mating pool with hope that it creates a better offspring. Partially Matched or Mapped Crossover (PMX) is the most widely used cros ...
Genetic Testing for Hereditary Breast and/or Ovarian Cancer
... Germline mutations in the BRCA1 and BRCA2 genes are responsible for cancer susceptibility in the majority of HBOC families, especially if ovarian cancer or male breast cancer are features. However, in site-specific breast cancer, BRCA mutations are responsible for only a proportion of affected famil ...
... Germline mutations in the BRCA1 and BRCA2 genes are responsible for cancer susceptibility in the majority of HBOC families, especially if ovarian cancer or male breast cancer are features. However, in site-specific breast cancer, BRCA mutations are responsible for only a proportion of affected famil ...
Dia 1 - BeSHG
... 2. Hemoglobin Synthesis Disorders (The Thalassemias) • collectively the most common human single-gene disorders! • carriers have an protective advantage against malaria • > qalassa (sea): first discovered in persons of Mediterranean origin • imbalance in the normal ratio of a : b chains - reduction ...
... 2. Hemoglobin Synthesis Disorders (The Thalassemias) • collectively the most common human single-gene disorders! • carriers have an protective advantage against malaria • > qalassa (sea): first discovered in persons of Mediterranean origin • imbalance in the normal ratio of a : b chains - reduction ...
(reversed and/or heterotaxic) phenotype in SWV mice
... 3). BC1 should show the G-odd effect since approximately li4 of its members are heterozygous for iu and homozygous for the putative "hi" gene that is hypothesized t o interact with i u i + t o result in the ii, phenotype. None of these offspring can be iuizu. RBCl should not show the G-odd effect si ...
... 3). BC1 should show the G-odd effect since approximately li4 of its members are heterozygous for iu and homozygous for the putative "hi" gene that is hypothesized t o interact with i u i + t o result in the ii, phenotype. None of these offspring can be iuizu. RBCl should not show the G-odd effect si ...
Close - Journal of Integrated OMICS
... Enterococci were obtained from 96 (98%) of the 98 samples analysed. E. hirae was the most prevalent detected species (35 isolates), followed by E. faecalis (30 isolates), E. faecium (27 isolates) and E. durans (4 isolates). E. coli isolates were detected in 90 (92%) of the 98 Iberian lynx faecal sam ...
... Enterococci were obtained from 96 (98%) of the 98 samples analysed. E. hirae was the most prevalent detected species (35 isolates), followed by E. faecalis (30 isolates), E. faecium (27 isolates) and E. durans (4 isolates). E. coli isolates were detected in 90 (92%) of the 98 Iberian lynx faecal sam ...
Engineered bacteriophage-defence systems in bioprocessing
... genetic content and genomic organization of these seven phages exhibit significant similarities to other members of the λ-superfamily of phages23. Bioinformatic analyses have provided significant insight into the evolution of S. thermophilus phages, revealing that their genomes are molecular mosaics ...
... genetic content and genomic organization of these seven phages exhibit significant similarities to other members of the λ-superfamily of phages23. Bioinformatic analyses have provided significant insight into the evolution of S. thermophilus phages, revealing that their genomes are molecular mosaics ...
n - HCC Learning Web
... Most DNA is packaged into chromosomes Humans have 46 chromosomes in their somatic cells, all cells of the body except gametes and their ...
... Most DNA is packaged into chromosomes Humans have 46 chromosomes in their somatic cells, all cells of the body except gametes and their ...
Analysis of Gene expression data using MATLAB Software
... one of the most frequently used methods for clustering gene expression profiles. However, commonly used methods for agglomerative hierarchical clustering rely on the setting of some score threshold to distinguish members of a particular cluster from non-members, making the determination of the numbe ...
... one of the most frequently used methods for clustering gene expression profiles. However, commonly used methods for agglomerative hierarchical clustering rely on the setting of some score threshold to distinguish members of a particular cluster from non-members, making the determination of the numbe ...
Practical: Ranges
... ## plot(as.integer(cvg), type="s", xlab="Coordinate", ylab="Depth of coverage") The run-length encoding can be interpreted as ‘a run of length 6 of nucleotides covered by 0 ranges, followed by a run of length 2 of nucleotides covered by 1 range. . . ’. Between methods act on two (or sometimes more) ...
... ## plot(as.integer(cvg), type="s", xlab="Coordinate", ylab="Depth of coverage") The run-length encoding can be interpreted as ‘a run of length 6 of nucleotides covered by 0 ranges, followed by a run of length 2 of nucleotides covered by 1 range. . . ’. Between methods act on two (or sometimes more) ...
no correlation between cyp17-34t/c polymorphism and severe acne
... A total of 41 Indonesian individuals participated in the study; 21 of them were patients presenting with acne including 15 males and 6 females, and 20 were healthy individuals used as control group including 9 males and 11 females. All participants in the study gave their signed informed consent. Al ...
... A total of 41 Indonesian individuals participated in the study; 21 of them were patients presenting with acne including 15 males and 6 females, and 20 were healthy individuals used as control group including 9 males and 11 females. All participants in the study gave their signed informed consent. Al ...
Genome position and gene amplification | SpringerLink
... these cells with respect to site specific response to drug challenge. We used array comparative genomic hybridization (CGH) to identify and classify the types of genomic alterations in the drug resistant cells, fluorescent in situ hybridization (FISH) to study the organization and mechanism of ampli ...
... these cells with respect to site specific response to drug challenge. We used array comparative genomic hybridization (CGH) to identify and classify the types of genomic alterations in the drug resistant cells, fluorescent in situ hybridization (FISH) to study the organization and mechanism of ampli ...
In vivo evidence for the prokaryotic model of extended codon
... binding site or on nucleotides following the initiation codon, which may (Moll et al., 2001) constitute a regulatory `downstream box'. What has not been reassessed is the possibility of extended interactions between the mRNA and the initiator tRNA (tRNAfMet). The question of extended tRNAfMet±mRNA b ...
... binding site or on nucleotides following the initiation codon, which may (Moll et al., 2001) constitute a regulatory `downstream box'. What has not been reassessed is the possibility of extended interactions between the mRNA and the initiator tRNA (tRNAfMet). The question of extended tRNAfMet±mRNA b ...