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the left atrium in hypertension: a symbol of mortality and morbidity?
the left atrium in hypertension: a symbol of mortality and morbidity?

... increased levels of systolic and pulse pressures (but not diastolic or mean arterial pressures) were significantly associated with an increased left atrial size. However, the inclusion of left ventricular mass in these multivariable models eliminated or attenuated the associations of the various blo ...
Echocardiographic Variables After Left Ventricular Assist Device
Echocardiographic Variables After Left Ventricular Assist Device

... patient outcome beyond this period. We postulated that the presence of echocardiographic variables 1 month after surgery suggesting appropriate degree of LV unloading and an adequate forward flow would be important in determining clinical outcomes after the initial successful LVAD implantation. Meth ...
NORMAL VARIATIONS AND THE INTERRELATIONS BETWEEN
NORMAL VARIATIONS AND THE INTERRELATIONS BETWEEN

... arteriolar resistance to blood flow in the lungs is small. As seen in Table I, pulmonary arteriolar resistance averaged 67 dynes seconds cm.-5 (15). In several recent publications (10, 16, 17) pulmonary vascular resistance has been calculated assuming an arbitrary figure for pressure in the left Com ...
Left Atrial Enlargement in Young High
Left Atrial Enlargement in Young High

... Introduction Athlete’s heart as a result of intensive, prolonged exercise has been investigated for many years. It has been suggested that training, especially in endurance sports, can lead to both left and right atrial enlargement (D'Andrea et al., 2010; Pagourelias et al., 2013; Pelliccia et al., ...
Diagnosis and evaluation of pulmonary hypertension
Diagnosis and evaluation of pulmonary hypertension

... Transthoracic echocardiography may also provide valuable clues about the presence of cardiac causes of PH, such as left ventricular systolic or diastolic dysfunction, mitral valve disease, and intracardiac shunting. Bubble contrast echocardiography provides information on significant intracardiac sh ...
Coexistence of Sick Sinus Rhythm and Atrial Flutter
Coexistence of Sick Sinus Rhythm and Atrial Flutter

... although a maj'or part of the right and left atria were in flutter and/ or fibrillation. The presence of an underlying sick sinus syndrome'31 is supported by (1) the presence of sinus bradycardia; (2) dampened response to atropine; (3) prolonged corrected sinus node recovery time, and (4) secondary ...
Left Atrial Enlargement and Reduced Physical Function During Aging
Left Atrial Enlargement and Reduced Physical Function During Aging

... and loss of independence. Subsequently, mortality rates are closely linked to disability in older individuals (Landi et al., 2010). The presumption, therefore, is that diastolic dysfunction may lead to physical limitations, which, in turn, contribute to disability. However, insufficient data are ava ...
Compression of interventricular septum during right - AJP
Compression of interventricular septum during right - AJP

... were investigated: 1) neo-Hookean (linear stress-strain) and 2) a sarcomere force-length (nonlinear stress-strain) relationship (10), implemented via an Arruda-Boyce energy function. Both models were made hyperelastic to account in part for any large strains associated with the PA constriction cycle ...
Print this article - Medical Journal of Indonesia
Print this article - Medical Journal of Indonesia

... add a potent thrombolytic agent into therapeutic regimen without increasing bleeding risk any further. Increasing evidence showed a promising efficacy and safety of oral fibrin specific lumbrokinase as a thrombolytic agent. To the best of our knowledge, report of the use of lumbrokinase on intracard ...
Growth differentiation factor-15 (GDF
Growth differentiation factor-15 (GDF

... studies have found that inflammation may play an important role in the occurrence and maintenance of atrial fibrillation [27, 28]. Therefore, GDF-15 as an inflammatory marker, it is speculated that it may be involved in the occurrence and development of atrial fibrillation. In this study, our result ...
Congenital cardiac surgery
Congenital cardiac surgery

... – Significant PDA : indicated after 1st month – Prophylactic closure : 6 -12 months – Sx. of heart failure or failure to thrive : indicated at any time ...
Atrial Fibrillation: New Horizons
Atrial Fibrillation: New Horizons

... Most recently the segmental approach is preferred because the myocardial fibers surrounding the PV are not continuous. Segments where musculature is present can be identified using high frequency depolarization signals recorded through multi-electrode loop catheter or even conventional catheters. (C ...
Left atrial strain in patients with arterial hypertension
Left atrial strain in patients with arterial hypertension

... filling were recorded from the apical 4-chamber view, by placing the sample volume at the level of the tips of the mitral valve leaflets and the centre of the forward LV filling jet. Early (E) and late (A) diastolic LV filling velocities were measured and E/A ratio was calculated. E/A ratio 29 and E ...
Iatrogenic Pericardial Effusion and Tamponade in the Percutaneous
Iatrogenic Pericardial Effusion and Tamponade in the Percutaneous

... The pressure within the structure that is perforated is a major determinant of the development and severity of tamponade. Thus a small perforation of the RV in an unanticoagulated patient may not be clinically apparent; in contrast, perforation of the RV in the setting of pulmonary hypertension or a ...
Anesthesia and Pulmonary Hypertension
Anesthesia and Pulmonary Hypertension

... risk that takes into consideration the type of surgery, patient's functional status, severity of disease including right ventricular function, and the patient's comorbidities. In addition, patients without a history who are at high risk for PH (e.g. scleroderma spectrum of diseases, obesity and obst ...
Pulmonary Hypertension in the Critically Ill
Pulmonary Hypertension in the Critically Ill

... and specificity identified in a recent metanalysis (Janda et al., 2011). The preferred approach is to apply the continuous wave spectral Doppler across the tricuspid valve from either the apical 4 chamber (A4C) and/or parasternal short axis (PSAX) view, with careful attention to the angle of insonat ...
Calorie Cycle What to do - Carnegie Science Center
Calorie Cycle What to do - Carnegie Science Center

... Blood vessels are hollow tubes that carry blood between the heart, different tissues, and organs of the body. There are three types of blood vessels: arteries, veins, and capillaries. These blood vessels have the ability to expand to allow more blood to flow through them. They can also contract to h ...
Mean pulmonary arterial pressures in Angus steers increase from
Mean pulmonary arterial pressures in Angus steers increase from

... the ARDEC, cattle were fed corn silage, whole corn, grass hay, and alfalfa. The ARDEC and the ECRC facilities were 206 km apart by road. In April of 2013, half of the steers (n = 61) were transported to the ARDEC. The steers were PAP tested 10 d after arriving at the ARDEC (Group A; May 2, 2013); th ...
Pulmonary Hypertension and Cardiovascular Sequelae in 54 Dogs
Pulmonary Hypertension and Cardiovascular Sequelae in 54 Dogs

... widely in severity. Pulmonary hypertension associated with left heart failure tends to be mild and can often be effectively managed, whereas dogs with severe pulmonary vascu- ...
Congenitally Corrected Transposition of the Great Arteries
Congenitally Corrected Transposition of the Great Arteries

... position, ventricular looping, and arterial looping. Morphology of the RV is seen on TTE by the presence of coarse trabeculations and a moderator band, whereas the LV has a smoothwalled endocardium and a funnel-shaped appearance. The level of the TV is inferior to the MV, which may also give a clue ...
UvA-DARE (Digital Academic Repository)
UvA-DARE (Digital Academic Repository)

... cardiac pathologies and congenital malformations. The understanding of early cardiac development, however, is complicated because it is inseparably associated with other developmental processes such as embryonic folding, formation of the coelomic cavity, and vascular development. Because of this, it ...
The Autonomic Nervous System and Atrial Fibrillation:The
The Autonomic Nervous System and Atrial Fibrillation:The

... junctional reentry (AVNRT) atrial flutter (AFL) and ventricular arrhythmias, clinical electrophysiologists have focused on the myocardial basis of atrial fibrillation (AF). Thus, the strategy for ablation of drug and cardioversion refractory AF was to isolate the myocardial connections from the foca ...
Antiarrhythmic Effect of Nifekalant on Atrial Tachyarrhythmia in Four
Antiarrhythmic Effect of Nifekalant on Atrial Tachyarrhythmia in Four

... and prevention of atrial fibrillation or flutter concomitant with heart failure. We found that intravenous nifekalant changed atrial flutter or multifocal atrial tachycardia with a rapid atrial rate to atrial tachycardia of longer cycle length and caused termination in some cases. Pure K channel blo ...
Repolarization Phase at Various Sites of the Right Atrium
Repolarization Phase at Various Sites of the Right Atrium

... were measured by the foregoing method and are shown in the expanded diagram of the right atrium (fig. 4). Depolarization and repolarization of eight different examples are illustrated in figure 4A and B, respectively. The isochronous lines indicate the approximate location of the wave front at 10-ms ...
Atrial Coronary Arteries: Anatomy And Atrial Perfusion
Atrial Coronary Arteries: Anatomy And Atrial Perfusion

... and posterior atrial branches. The left anterior atrial branch arises on the anterior aspect of the LA (Figure 1). When it is the main atrial branch, it courses upwards along the LA via the anterior interatrial groove to reach the SAN. In RAO projection, it is an early branch which ascends leftwards ...
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Atrial septal defect



Atrial septal defect (ASD) is a congenital heart defect in which blood flows between the atria (upper chambers) of the heart. Normally, the atria are separated by a dividing wall, the interatrial septum. If this septum is defective or absent, then oxygen-rich blood can flow directly from the left side of the heart to mix with the oxygen-poor blood in the right side of the heart, or vice versa. This can lead to lower-than-normal oxygen levels in the arterial blood that supplies the brain, organs, and tissues. However, an ASD may not produce noticeable signs or symptoms, especially if the defect is small.A ""shunt"" is the presence of a net flow of blood through the defect, either from left to right or right to left. The amount of shunting present, if any, determines the hemodynamic significance of the ASD. A ""right-to-left-shunt"" typically poses the more dangerous scenario.During development of the fetus, the interatrial septum develops to separate the left and right atria. However, a hole in the septum called the foramen ovale, allows blood from the right atrium to enter the left atrium during fetal development. This opening allows blood to bypass the nonfunctional fetal lungs while the fetus obtains its oxygen from the placenta. A layer of tissue called the septum primum acts as a valve over the foramen ovale during fetal development. After birth, the pressure in the right side of the heart drops as the lungs open and begin working, causing the foramen ovale to close entirely. In approximately 25% of adults, the foramen ovale does not entirely seal. In these cases, any elevation of the pressure in the pulmonary circulatory system (due to pulmonary hypertension, temporarily while coughing, etc.) can cause the foramen ovale to remain open. This is known as a patent foramen ovale (PFO), which is a type of atrial septal defect.
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