Mark J. Mannis, MD
... Research in the United States. In 2012, 45 UC Davis faculty, with nearly $22M in grant support, studied all aspects of visual function, from molecular biology of the cornea, to visual cognition in the brain, from nano-engineering of the trabecular meshwork, to stem cell treatment for retinal disease ...
... Research in the United States. In 2012, 45 UC Davis faculty, with nearly $22M in grant support, studied all aspects of visual function, from molecular biology of the cornea, to visual cognition in the brain, from nano-engineering of the trabecular meshwork, to stem cell treatment for retinal disease ...
Microsaccadic eye movements and firing of single cells in the striate
... the most appropriate ISI for any given cell, we compared, for all the records and for all the cells, all ISIs between 1 and 100 ms and Instantaneous firing rate measured the probability of a microsaccade occurring some time We examined the relationship between the interspike intervals (latency; ≤ 20 ...
... the most appropriate ISI for any given cell, we compared, for all the records and for all the cells, all ISIs between 1 and 100 ms and Instantaneous firing rate measured the probability of a microsaccade occurring some time We examined the relationship between the interspike intervals (latency; ≤ 20 ...
vitreous hemorrhage in post victretomized eye
... internal limiting membrane, and laterally by the ciliary body and lens zonular fibers. In a vitrectomized eye, blood can remain in a liquefied state and often requires the use of high gain settings in dynamic B-scan ultrasound to visualize and diagnose the hemorrhage [4]. A pars plana vitrectomy is ...
... internal limiting membrane, and laterally by the ciliary body and lens zonular fibers. In a vitrectomized eye, blood can remain in a liquefied state and often requires the use of high gain settings in dynamic B-scan ultrasound to visualize and diagnose the hemorrhage [4]. A pars plana vitrectomy is ...
Color matches of patients with retinitis pigmentosa.
... Reprint requests: Rockefeller S. L. Young, Eye and Ear Infirmary, University of Illinois, 1855 W. Taylor St., Chicago, 111. 60612. ...
... Reprint requests: Rockefeller S. L. Young, Eye and Ear Infirmary, University of Illinois, 1855 W. Taylor St., Chicago, 111. 60612. ...
Dominantly inherited unilateral retinal dysplasia
... who died aged 84 ten years ago was described by the family as having a 'small abnormal right eye which was blind.' It apparently 'turned in and had a white pupil.' This is corroborated by the pathology notes of the infant's mother. She apparently had no surgery for this and no problems with her othe ...
... who died aged 84 ten years ago was described by the family as having a 'small abnormal right eye which was blind.' It apparently 'turned in and had a white pupil.' This is corroborated by the pathology notes of the infant's mother. She apparently had no surgery for this and no problems with her othe ...
Session 161 Posterior segment mechanisms and functions
... Tannin A. Schmidt2. 1Medical Sciences, University of Calgary, Calgary, AB, Canada; 2Kinesiology, University of Calgary, Calgary, AB, Canada; 3University of Calgary, Calgary, AB, Canada. Purpose: Purpose: Proteoglycan 4 (PRG4) / lubricin is a mucin-like glycoprotein originally discovered in synovial ...
... Tannin A. Schmidt2. 1Medical Sciences, University of Calgary, Calgary, AB, Canada; 2Kinesiology, University of Calgary, Calgary, AB, Canada; 3University of Calgary, Calgary, AB, Canada. Purpose: Purpose: Proteoglycan 4 (PRG4) / lubricin is a mucin-like glycoprotein originally discovered in synovial ...
ophth-notes - WordPress.com
... Tears/lacrimal fluid made by lacrimal gland S/T Lacrimal gland alone innervated by facial nerve as a reflex but produced by various other structures; e.g. meibomian gland, lacrimal gland etc. 1.2ul/min produced with approx. 6uL within the eye at any time Drainage occurs via S and I punctum, via ampu ...
... Tears/lacrimal fluid made by lacrimal gland S/T Lacrimal gland alone innervated by facial nerve as a reflex but produced by various other structures; e.g. meibomian gland, lacrimal gland etc. 1.2ul/min produced with approx. 6uL within the eye at any time Drainage occurs via S and I punctum, via ampu ...
What is the History of Medieval Optics Really About?1
... beside the point. The path that led to them was the same; Kepler simply followed it more rigorously. It would therefore seem reasonable to conclude with Lindberg that, in sharing the same analytic principles, Alhacen and Kepler operated within the same conceptual framework. But this conclusion is gr ...
... beside the point. The path that led to them was the same; Kepler simply followed it more rigorously. It would therefore seem reasonable to conclude with Lindberg that, in sharing the same analytic principles, Alhacen and Kepler operated within the same conceptual framework. But this conclusion is gr ...
Ocular Surface Disorders —Reconstruction of transparent tissues
... cells become available, not only transplantation medicine, but also the quality of medicine as a whole would be expected to change. If extracorporeal generation of tissues or organs by means of tissue culture succeeds, it will pave the way for regeneration medicine, in which not only transplantation ...
... cells become available, not only transplantation medicine, but also the quality of medicine as a whole would be expected to change. If extracorporeal generation of tissues or organs by means of tissue culture succeeds, it will pave the way for regeneration medicine, in which not only transplantation ...
PS103 - Vision
... • Individual neurones in V4 respond to a variety of wavelengths • Also some coding for orientation (may be colour specific) • PET studies show • more activation in V4 to coloured pattern than to grey tone • no difference if coloured pattern is stationary or moving • Achromatopsia • damage to V4 caus ...
... • Individual neurones in V4 respond to a variety of wavelengths • Also some coding for orientation (may be colour specific) • PET studies show • more activation in V4 to coloured pattern than to grey tone • no difference if coloured pattern is stationary or moving • Achromatopsia • damage to V4 caus ...
Eye Anatomy and Function Pre
... Imagine if the lens was opaque instead of transparent. How would that affect vision? Cataract occurs when part of the lens becomes opaque inhibiting the amount of light that is focused onto the retina. One cause of cataract is aggregated lens proteins causing a reduction in transparency. The structu ...
... Imagine if the lens was opaque instead of transparent. How would that affect vision? Cataract occurs when part of the lens becomes opaque inhibiting the amount of light that is focused onto the retina. One cause of cataract is aggregated lens proteins causing a reduction in transparency. The structu ...
Mast cells in human optic nerve.
... Purpose. Mast cells are classically found in ocular tissues within the conjunctiva, choroid, and iris. The aim of this study was to examine their distribution in the optic nerve and its meninges. Methods. Sixty-six human optic nerves were studied from normal subjects at autopsy, fetuses aborted for ...
... Purpose. Mast cells are classically found in ocular tissues within the conjunctiva, choroid, and iris. The aim of this study was to examine their distribution in the optic nerve and its meninges. Methods. Sixty-six human optic nerves were studied from normal subjects at autopsy, fetuses aborted for ...
Examination of the eye
... Aqueous humour – this transparent fluid fills the anterior and posterior chamber. It is made by the ciliary body and drained through the iridocorneal (drainage) angle. It is responsible for providing essential nutrition and oxygen to the delicate internal structures of the eye and it absorbs waste p ...
... Aqueous humour – this transparent fluid fills the anterior and posterior chamber. It is made by the ciliary body and drained through the iridocorneal (drainage) angle. It is responsible for providing essential nutrition and oxygen to the delicate internal structures of the eye and it absorbs waste p ...
Jeannerod (1979) Corollary discharge. Its possible
... Abstract--Data concerning the possible role of a corollary discharge mechanism in the regulation of visual-oculomotor interactions are reviewed. Several modes of action for such a mechanism on the processing of visual information are discussed. Mere suppression of visual input during saccades is con ...
... Abstract--Data concerning the possible role of a corollary discharge mechanism in the regulation of visual-oculomotor interactions are reviewed. Several modes of action for such a mechanism on the processing of visual information are discussed. Mere suppression of visual input during saccades is con ...
Proton irradiation of simulated ocular tumors.
... on a scale drawing of the owl monkey eye and orbit (Fig. 5). The depth-dose characteristics of the 10 mm. beam were similar to those of the 7 mm. beam. About 55 per cent of the peak dose was delivered to the sclera at the entry point opposite the target area. A circumscribed opaque area of edematous ...
... on a scale drawing of the owl monkey eye and orbit (Fig. 5). The depth-dose characteristics of the 10 mm. beam were similar to those of the 7 mm. beam. About 55 per cent of the peak dose was delivered to the sclera at the entry point opposite the target area. A circumscribed opaque area of edematous ...
Foveal cone ERGs in fellow eyes of patients with unilateral
... neovascular AMD and for normals. Data have been adjusted for the significant effect of iris pigmentation on amplitude. Foveal cone ERG amplitudes, which were positively skewed, were converted to common logarithms (log10) to approximate a normal distribution. Amplitude and implicit time were each reg ...
... neovascular AMD and for normals. Data have been adjusted for the significant effect of iris pigmentation on amplitude. Foveal cone ERG amplitudes, which were positively skewed, were converted to common logarithms (log10) to approximate a normal distribution. Amplitude and implicit time were each reg ...
Optic nerve transection in cats: effect on retinal vessels.
... vitreous showed that the hydroxyproline content was 3.1 per cent w/w compared to a value of 10.9 per cent w/w for equivalent samples obtained from cattle. In contrast to the discreet fibers in bovine vitreous, the rabbit constituents occur as an aggregate of fibrils with a diameter of 15 to 20 A. Th ...
... vitreous showed that the hydroxyproline content was 3.1 per cent w/w compared to a value of 10.9 per cent w/w for equivalent samples obtained from cattle. In contrast to the discreet fibers in bovine vitreous, the rabbit constituents occur as an aggregate of fibrils with a diameter of 15 to 20 A. Th ...
Patient-specific induced pluripotent stem cells (iPSCs) for the study
... Vision is the sense that we use to navigate the world around us. Thus it is not surprising that blindness is one of people's most feared maladies. Heritable diseases of the retina, such as age-related macular degeneration and retinitis pigmentosa, are the leading cause of blindness in the developed ...
... Vision is the sense that we use to navigate the world around us. Thus it is not surprising that blindness is one of people's most feared maladies. Heritable diseases of the retina, such as age-related macular degeneration and retinitis pigmentosa, are the leading cause of blindness in the developed ...
Posterior scleritis with retinal vasculitis and choroidal and retinal
... failed to identify any cases where retinal vasculitis predominated or where choroidal infarction occurred. Optic disc swelling is a recognised feature of posterior scleritis. In this case with such extensive vascular involvement it is possible that direct infarction of the optic nerve head could hav ...
... failed to identify any cases where retinal vasculitis predominated or where choroidal infarction occurred. Optic disc swelling is a recognised feature of posterior scleritis. In this case with such extensive vascular involvement it is possible that direct infarction of the optic nerve head could hav ...
From the optic tectum to the primary visual cortex
... thus not having face detectors in V1 cannot be an argument against V1’s role in the saliency of a visual location on a face. A case of looking or attending before seeing or recognizing the visual object at the attended location is dramatically demonstrated in the strong saliency of the eye-of-origin ...
... thus not having face detectors in V1 cannot be an argument against V1’s role in the saliency of a visual location on a face. A case of looking or attending before seeing or recognizing the visual object at the attended location is dramatically demonstrated in the strong saliency of the eye-of-origin ...
You Can`t Afford To Miss This! - American Academy of Optometry
... • Lung cancer metastasis rarely bilateral and multifocal • They often produce pain • Lung cancer metastasis 70% of patients don’t know they have cancer ...
... • Lung cancer metastasis rarely bilateral and multifocal • They often produce pain • Lung cancer metastasis 70% of patients don’t know they have cancer ...
Clinical Anatomy of the Trigeminal Nerve
... named for its three major sensory branches. The ophthalmic nerve (V1), maxillary nerve (V2), and mandibular nerve (V3) are literally "three twins" carrying information about light touch, temperature, pain, and proprioception from the face and scalp to the brainstem. • The three branches converge on ...
... named for its three major sensory branches. The ophthalmic nerve (V1), maxillary nerve (V2), and mandibular nerve (V3) are literally "three twins" carrying information about light touch, temperature, pain, and proprioception from the face and scalp to the brainstem. • The three branches converge on ...
Limbal Epithelial Stem Cells in Corneal Regeneration
... equivalent to the life of the organism in which they reside. 4. Stem cells exhibit extremely low rates of proliferation (indicates low mitotic activity). They have a long cell cycle time or slow cycling. 5. LSC can undergo symmetric or asymmetric division depending upon the conditions. When cell u ...
... equivalent to the life of the organism in which they reside. 4. Stem cells exhibit extremely low rates of proliferation (indicates low mitotic activity). They have a long cell cycle time or slow cycling. 5. LSC can undergo symmetric or asymmetric division depending upon the conditions. When cell u ...
Geng, Y., Greenberg, K.P., Wolfe, R., Gray, D.C., Hunter, J.J., Dubra
... substantial modifications in the morphology of axons and dendrites can take place well before cell death.2– 8 These observations highlight the need to develop high-resolution in vivo imaging techniques capable of resolving subcellular structures (such as individual axons and dendrites) in rodent eye ...
... substantial modifications in the morphology of axons and dendrites can take place well before cell death.2– 8 These observations highlight the need to develop high-resolution in vivo imaging techniques capable of resolving subcellular structures (such as individual axons and dendrites) in rodent eye ...
Photoreceptor cell
A photoreceptor cell is a specialized type of neuron found in the retina that is capable of phototransduction. The great biological importance of photoreceptors is that they convert light (visible electromagnetic radiation) into signals that can stimulate biological processes. To be more specific, photoreceptor proteins in the cell absorb photons, triggering a change in the cell's membrane potential.The two classic photoreceptor cells are rods and cones, each contributing information used by the visual system to form a representation of the visual world, sight. The rods are narrower than the cones and distributed differently across the retina, but the chemical process in each that supports phototransduction is similar. A third class of photoreceptor cells was discovered during the 1990s: the photosensitive ganglion cells. These cells do not contribute to sight directly, but are thought to support circadian rhythms and pupillary reflex.There are major functional differences between the rods and cones. Rods are extremely sensitive, and can be triggered by a single photon. At very low light levels, visual experience is based solely on the rod signal. This explains why colors cannot be seen at low light levels: only one type of photoreceptor cell is active.Cones require significantly brighter light (i.e., a larger numbers of photons) in order to produce a signal. In humans, there are three different types of cone cell, distinguished by their pattern of response to different wavelengths of light. Color experience is calculated from these three distinct signals, perhaps via an opponent process. The three types of cone cell respond (roughly) to light of short, medium, and long wavelengths. Note that, due to the principle of univariance, the firing of the cell depends upon only the number of photons absorbed. The different responses of the three types of cone cells are determined by the likelihoods that their respective photoreceptor proteins will absorb photons of different wavelengths. So, for example, an L cone cell contains a photoreceptor protein that more readily absorbs long wavelengths of light (i.e., more ""red""). Light of a shorter wavelength can also produce the same response, but it must be much brighter to do so.The human retina contains about 120 million rod cells and 6 million cone cells. The number and ratio of rods to cones varies among species, dependent on whether an animal is primarily diurnal or nocturnal. Certain owls, such as the tawny owl, have a tremendous number of rods in their retinae. In addition, there are about 2.4 million to 3 million ganglion cells in the human visual system, the axons of these cells form the 2 optic nerves, 1 to 2% of them photosensitive.The pineal and parapineal glands are photoreceptive in non-mammalian vertebrates, but not in mammals. Birds have photoactive cerebrospinal fluid (CSF)-contacting neurons within the paraventricular organ that respond to light in the absence of input from the eyes or neurotransmitters. Invertebrate photoreceptors in organisms such as insects and molluscs are different in both their morphological organization and their underlying biochemical pathways. Described here are human photoreceptors.