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Molecular Mechanisms of Myocardial Remodeling
Molecular Mechanisms of Myocardial Remodeling

... Early ventricular remodeling following coronary occlusion is dominated by infarct expansion, which is an acute dilation of the infarction area that cannot be explained by additional myocardial necrosis. Infarct expansion is caused by death and slippage of the myocytes; it usually predominates in the ...
Electrical alternansin cardiac tamponade
Electrical alternansin cardiac tamponade

... in heart rate/alternans rate ratios 2: 1, 3: 1, and 4: 1 (Table III) can be explained by assuming that the frequency of the cardiac cyclic motion is one-half, one-third, and one-quarter respectively of the heart rate (Figs 3, 4, and 5). Likewise a cardiac motion with varying frequency and plane coul ...
Anastomoses Between Bronchial and Coronary Circulation in a
Anastomoses Between Bronchial and Coronary Circulation in a

... Their revascularisation could be achieved using either the pedicled mammary artery or an aortic button, as occurs in lung transplantation cases.21,22 Moreover, in similar cases, but without ischaemic heart disease, it seems that the coronary arteries can contribute to the bronchial circulation becau ...
Pulmonary atresia with intact ventricular septum
Pulmonary atresia with intact ventricular septum

... thanks to a persistent ductus arteriosus, but such cases are extremely rare (Robicsek et al. 1966). The history of congenital heart surgery Cardiac surgery is an accomplishment of the twentieth century. The first reported successful case of cardiac surgery was the ligation of a patent ductus arterio ...
with abnormalities of atrioventricular conduction Genetic study of
with abnormalities of atrioventricular conduction Genetic study of

... where one or more of the first degree relatives were found to have an atrial septal defect or a conduction defect, or both, I5 more distant relatives also were examined as above, and adequate diagnostic information was obtained on three who had died. In three families (A, B, and C) one or more of th ...
Surgery for Atrial Fibrillation - ANNALS Academy of Medicine
Surgery for Atrial Fibrillation - ANNALS Academy of Medicine

... discomfort and anxiety; (2) loss of synchronous atrioventricular contraction which compromises cardiac haemodynamics; and (3) stasis of blood flow in the left atrium, which increases vulnerability to thromboembolism.13 While early attempts at surgical control of medically refractory atrial fibrillat ...
State of the Art: Degenerative Mitral Valve Disease
State of the Art: Degenerative Mitral Valve Disease

... of a “pathophysiological triad”. The regurgitant valve is described first by disease aetiology (e.g. fibroelastic deficiency, Barlow’s disease) then by the primary lesion (e.g. chordal rupture, annular dilatation); and finally by the resultant leaflet dysfunction relating to the motion of the leaflet marg ...
Passamani-2014-Temporal profile and mechanisms
Passamani-2014-Temporal profile and mechanisms

... phenylephrine injection; (iii) an elevated cardiac sympathetic tone (DHR after atenolol: 210868 versus 28267 bpm in Sham, P,0.05). In contrast, no changes were observed in cardiac vagal tone and bradycardic response to both baroreflex and chemoreflex between LAD and Sham groups. The immediate sympat ...
OVEREXPRESSION OF ANG-(1-7) OR CARDIAC-SELECTIVE OVEREXPRESSION
OVEREXPRESSION OF ANG-(1-7) OR CARDIAC-SELECTIVE OVEREXPRESSION

... atherosclerotic plaque. Risk factors include previous history of vascular disease (such as atherosclerosis), angina, a previous heart attack or stroke, and age (especially men over 40 and women over 50 years). According to a report from the American Heart Association Statistics Committee, an estimat ...
cardiac rhythm and atrial transport function after surgical ablation of
cardiac rhythm and atrial transport function after surgical ablation of

... Methods. Between January 2005 and September 2006, 100 consecutive patients underwent left atrial cryoablation as a concomitant surgical procedure (46 patients with paroxysmal or persistent atrial fibrillation and 54 with permanent atrial fibrillation). Mitral valve surgery was performed in 74%. The ...
Optimal pacing strategies for coming off CPB
Optimal pacing strategies for coming off CPB

... In DVI mode, sensing of an intrinsic ventricular depolarization (following either an atrial pacing spike or intrinsic atrial depolarization), inhibits ventricular pacing. In the absence of any intrinsic cardiac depolarization, the pacemaker behaves like a DOO. Since there is no atrial sensing, ther ...
Cardiac Surgery Simulation Curriculum
Cardiac Surgery Simulation Curriculum

... Richard H. Feins, M.D., University of North Carolina at Chapel Hill, Chapel Hill, NC (Principal Investigator) Harold M. Burkhart, M.D., Mayo Clinic, Rochester, MN Daniel N. Coore, Ph.D., University of the West Indies, Mona, Jamaica John V. Conte, M.D., Johns Hopkins University, Baltimore, MD James I ...
Percutaneous mitral valve repair: an overview of new interventional
Percutaneous mitral valve repair: an overview of new interventional

... does not occur at the time of implantation and the degree of MR reduction cannot be known until at least several weeks have passed.  The experience with this device in Phase I trials has clearly demonstrated that MR can be diminished. A majority of patients have a decrease in one grade of MR severit ...
ECG Recording - Learning Central
ECG Recording - Learning Central

... There are quite a variety of equipment to do just that, although the basic aspects and features of each equipment are similar. It’s helpful therefore to familiarise yourself with a machine you come across on the ward, and ask the Nurse to show how to use it on a patient. This advice particularly hol ...
- Journal of the Saudi Heart Association
- Journal of the Saudi Heart Association

... Anomalous right coronary artery is a rare entity with an incidence of 0.26%. The anomalous origin usually arises from the left sinus valsalva. An anomalous right coronary artery arising from the left anterior descending artery is rare. It is usually known as a benign entity but may have clinical imp ...
Role of Cardiac Myocyte CXCR4 Expression in Development and
Role of Cardiac Myocyte CXCR4 Expression in Development and

... nation, we quantified CXCR4 deletion by performing quantitative PCR on the mice treated daily with 40 mg/kg IP of tamoxifen dissolved in corn oil for 2, 4, 6, and 8 days. Using the same PCR strategy described above, we observed no further deletion of CXCR4 following tamoxifen administration beyond 4 ...
Congenital diaphragmatic hernia with concurrent aplasia of the
Congenital diaphragmatic hernia with concurrent aplasia of the

... Even if CDH is anatomically a simple defect, depending on the size of the diaphragmatic foramen, it is often observed associated with unilateral lung hypoplasia and with malposition of the abdominal organs (more frequently small intestine loops, and rarely, liver, spleen and stomach) in the thorax [ ...
Third universal definition of myocardial infarction
Third universal definition of myocardial infarction

... prolonged ischemia. After the onset of myocardial isch­ emia, histological cell death is not immediate, but takes a finite period of time to develop—as little as 20 min, or less in some animal models.4 It takes several hours before myocardial necrosis can be identified by macroscopic or microscopic ...
Pericarditis Guide
Pericarditis Guide

... normal rhythm. These symptoms should improve when the constrictive pericarditis is treated. Constrictive pericarditis often can be treated with a diuretic, such as furosemide, to treat the fluid retention. If you develop a heart rhythm problem, you may need to take a medication to treat the irregula ...
Left ventricular diastolic collapse in regional left heart
Left ventricular diastolic collapse in regional left heart

... life-saving in patients with pericardial effusion . Echocardiography has been shown to be useful in the evaluation of ...
Amiodarone Supplants Lidocaine in ACLS and CPR Protocols
Amiodarone Supplants Lidocaine in ACLS and CPR Protocols

... rate and amplitude indicates the inconsistent and hectic electrical activity and contraction when the heart stops pumping. VF waveforms often weaken to asystole within 15 minutes.2 In countries with prosperous resources, such as the United States and Europe, cardiac arrest due to VT or VF is mostly ...
Coronary anomalies: single centre experience
Coronary anomalies: single centre experience

... silent and usually are found incidentally during angiographic evaluation for other cardiac diseases. Certain types of anomalies that are associated with impaired myocardial perfusion can result in angina, congestive heart failure, myocardial infarction, cardiomyopathy, ventricular aneurysms, or sudd ...
DORV DR KSHITIJ
DORV DR KSHITIJ

... Because coarctation of the aorta is commonly observed in this situation, patients may have undergone coarctation repair with a pulmonary artery band  The subsequent procedure is a single stage complete repair with VSD enlargement if restrictive, repair of the VSD to direct the left ventricular blo ...
The Fontan circulation: who controls cardiac output?
The Fontan circulation: who controls cardiac output?

... that augmentation of cardiac output is extremely dependent upon preload reserve. Exercise induced increases in cardiac output are partly explained by the Frank Starling mechanism, but left ventricular filling is more important than myocardial contractility in augmenting stroke volume in normal indiv ...
Cardiac sympathetic afferent stimulation impairs - AJP
Cardiac sympathetic afferent stimulation impairs - AJP

... free of the surrounding connective tissue, and was placed on a pair of platinum-iridium recording electrodes. When an optimal signal-tonoise ratio was achieved, the electrode and the renal nerve were covered with a fast setting silicone (Kwik-Sil, World Precision Instruments; Sarasota, FL). The sign ...
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Cardiothoracic surgery



Cardiothoracic surgery is the field of medicine involved in surgical treatment of diseases affecting organs inside the thorax (the chest)—generally treatment of conditions of the heart (heart disease) and lungs (lung disease). Cardiac surgery (involving the heart and great vessels) and thoracic surgery (involving the lungs) are separate surgical specialties, except in the USA, Australia, New Zealand and in some EU countries, such as the UK and Portugal.
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