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Equine allogeneic bone marrow-derived mesenchymal stromal cells
Equine allogeneic bone marrow-derived mesenchymal stromal cells

... The use of autologous mesenchymal stromal/stem cells (MSCs) for the treatment of acute injuries is hindered by the time required to isolate and expand the cells in culture. The genetic background and age of the patient can also affect the quantity and quality of MSCs able to be cultured, making aut ...
fmd with viaa test incl.
fmd with viaa test incl.

... anticoagulant can be used undiluted as the inoculum. After 15–60 minutes of adsorption at ambient temperature or at 37°C, the cell cultures are washed and maintenance medium is added. Alternatively and more commonly, the blood is washed, lysed and diluted 1/10. This procedure removes unwanted antibo ...
Regulation of mucosal immune responses in effector sites
Regulation of mucosal immune responses in effector sites

... hypothesised that the changes occur as a result of transient allergic immune responses to novel food or bacteria antigens. The normal mechanism for producing tolerance to food antigens may operate at induction (Peyer’s patches and mesenteric lymph nodes) or at the effector stage (intestinal lamina p ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... inhibiting the production of Th1 cytokines (Feliciano et al. , 2014). Th1 cytokines inhibit trophoblast invasion, stimulate apoptosis of human trophoblast cells, and enhance decidual macrophage activity, all of which result in the production of factors harmful to the embryo (Lee et al. , 2011). Cyto ...
Passenger Lymphocyte Syndrome and Liver Transplantation
Passenger Lymphocyte Syndrome and Liver Transplantation

... Three different groups of ABO incompatibility can be distinguished in transplantation: minor, major, and bidirectional ABO incompatibility. Major ABO-incompatible (e.g., A into O) is characterized by the presence of preformed antidonor A/B Ab directed against donor ABO Ag expressed on transplanted ce ...
Identification of the major proteins present in the seminal
Identification of the major proteins present in the seminal

... Immune system proteins (Complement C3) could have an immunologic role against microbial infection in the final stages of sperm maturation. ...
The role of autoantibodies in health and disease
The role of autoantibodies in health and disease

... animals [27]. The most important characteristic of NAA is their permanent presence in different compartments of the body (e.g., blood stream, interstitial fluid, lymphatics). The content of IgG autoantibodies with defined specificities is nearly the same in capillary, venous or arterial blood. The b ...
Fatal canine adenovirus type 1 acute infection in a Yorkshire Terrier
Fatal canine adenovirus type 1 acute infection in a Yorkshire Terrier

... tissues and a friable uniformly yellow mottled liver. Differential diagnosis based on PCR ruled out the presence of most common gastrointestinal canine viruses and bacteriology and coprology confirmed that pathogenic bacteria and intestinal parasites did not account for the puppy’s death. Strong amp ...
Transcutaneous vaccination via laser microporation
Transcutaneous vaccination via laser microporation

... laser beam and a fixed spot diameter of several millimeters have been employed [32–41]. Compared to fractional ablative systems, these devices remove a much larger amount of skin surface leading to a prolonged healing time. More recently, conventional fractional ER: YAG lasers have been employed, wh ...
陶秘華 Mi-Hua Tao Institution Institute of Biomedical Sciences
陶秘華 Mi-Hua Tao Institution Institute of Biomedical Sciences

... HBV are usually weak and accompanied with various levels of T-cell dysfunctions. The research focus of my laboratory is to understand mechanisms responsible for immune tolerance to HBV, and to develop novel therapeutic strategies to treat chronic HBV and HBV-associated HCC. We developed several HBV ...
Section III - Immunization of Special Populations
Section III - Immunization of Special Populations

... influenzae type b (Hib). In some immunocompromised individuals, even a less than optimal response to vaccine may provide important benefit as they may be at high risk of morbidity and mortality due to vaccine-preventable infection. Only HSCT clients require re-immunization after treatment, due to th ...
Timeline – Hepatitis Milestones
Timeline – Hepatitis Milestones

... Recent Developments in the Story of Hepatitis Hepatitis A outbreak in Pennsylvania caused by green onions kills three and sickens at least 575 people; other hepatitis outbreaks in Georgia and Tennessee sicken over 300 people Actress Pamela Anderson announces she has HCV An estimated 40 million infan ...
Characterization of a surface antigen of Type="Italic
Characterization of a surface antigen of Type="Italic

... 3C3 recognizes a surface antigen on these organisms. This was also confirmed by immunoprecipitation data, since mcab 3C3 immunoprecipitates a radioactive protein comigrating with polypeptide found by iodinating sporozoites via the lactoperoxidase procedure. When electrophoresed under reducing condit ...
Effects of supplementation with tocotrienol-rich fraction on
Effects of supplementation with tocotrienol-rich fraction on

... 1997a, b) and Brown Norway rats (Gu et al., 1999). However, the effects of tocotrienol on the human immune system following immunization have not been investigated. Activated T cells can differentiate into effector T cells showing distinct patterns of cytokine production. The T-helper-1 (TH1) cells, ...
CHAPTER III
CHAPTER III

... In sheep, a large infiltration of white blood cells into the liver and production of antibodies to the parasite have been observed (Sinclair, 1962, 1971; Boray, 1967, 1969; Ross et al., 1967; Movsesijan et al., 1975; Knight, 1980; Sandeman and Howell, 1980a, 1980b; Wedrychowicz et al., 1984; Boyce e ...
Immunomodulatory activity of MunroniapumilaWight. (Meliaceae
Immunomodulatory activity of MunroniapumilaWight. (Meliaceae

... Lankan traditional medicine to treat a variety of ailments on the belief that it can enhance immune system. However, scientific evidence supporting this notion is lacking. Present study was undertaken to study immune responses of M. pumila leaf extractions in rats. The crude product of the dried lea ...
Influence of honey in mice bearing Ehrlich carcinoma
Influence of honey in mice bearing Ehrlich carcinoma

... 3rd International Conference and Exhibition on Clinical & Cellular Immunology September 29 - October 01, 2014 Baltimore, USA ...
Figure 2 - Essays in Biochemistry
Figure 2 - Essays in Biochemistry

... found in the blood, in tissue fluids or bound to the cell surface. The antibody receptor, also called an immunoglobulin (Ig), was the first antigen-specific receptor to be characterized and is commonly drawn as a Y-shaped cartoon. It is formed by the combination of two identical heavy and two identi ...
May 2006 - InvivoGen
May 2006 - InvivoGen

... Increasing the serum persistence of a therapeutic antibody is another way to improve its efficacy, allowing higher circulating levels, less frequent administration and reduced doses. This can be achieved by enhancing the binding of the Fc region to neonatal FcR (FcRn). FcRn, which is expressed on th ...
exam three study guide
exam three study guide

... examples of each give in class. Innate Immunity 1. Know the steps of phagocytosis. 2. Know the examples of mechanical/physical defenses. 3. Know the examples of chemical defenses and how each works. 4. Know what complements are and the examples given in class. 5. Know the functions of fever and what ...
Windows of opportunity for Ebola virus infection treatment
Windows of opportunity for Ebola virus infection treatment

... Ebola virus (EBOV) infection causes a high death toll, killing a high proportion of EBOV infected patients within 7 days. Comprehensive data on EBOV infection are very fragmented, hampering efforts in developing therapeutics and vaccines against EBOV. Under this circumstance, mathematical models bec ...
Discovery and Use of a Natural Mutation that Results in Severe
Discovery and Use of a Natural Mutation that Results in Severe

... successfully transplanted, however five showed signs of graft versus host disease after transfer and were euthanized. The four surviving transplanted piglets were documented to have a reconstituted adaptive immune system. ...
Lymphatic System
Lymphatic System

... DNA  May be long term or life long ...
roles in innate immune receptors: host - pathogen
roles in innate immune receptors: host - pathogen

... pivotal for discriminating self from non-self and friend from foe, but not as specific as the adaptive immune system. However, it is a sophisticated system that also has a role in orchestrating the adaptive responses. Innate immune responses can be elicited in nearly all known cell types. Physical b ...
IMMUNOREGULATION OF HEPATITIS B VIRUS INFECTION
IMMUNOREGULATION OF HEPATITIS B VIRUS INFECTION

... to protect against the infection of newly intruding HBV in more than 90% of vaccinees, if properly administered.26) However, therapeutic use of this HBsAg vaccine has not brought satisfactory results for controlling viral replication at present.27.28) Therefore, a new vaccine or novel strategy is de ...
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Immunocontraception

In the strictest sense immunocontraception is the use of an animal's immune system to prevent it from fertilizing offspring. More generally the field of immunocontraception includes related technologies that prevent embryonic implantation.Typically immunocontraception involves the administration of a vaccine that induces an adaptive immune response which causes an animal to become temporarily infertile. Contraceptive vaccines have been used in numerous settings for the control of wildlife populations. However, experts in the field believe that major innovations are required before immunocontraception can become a practical form of contraception for human beings.Thus far immunocontraception has focused on mammals exclusively. There are several targets in mammalian sexual reproduction for immune inhibition. They can be organized into three categories.Gamete production Organisms that undergo sexual reproduction must first produce gametes, cells which have half the typical number of chromosomes of the species. Often immunity that prevents gamete production also inhibits secondary sexual characteristics and so has effects similar to castration.Gamete function After gametes are produced in sexual reproduction, two gametes must combine during fertilization to form a zygote, which again has the full typical number of chromosomes of the species. Methods that target gamete function prevent this fertilization from occurring and are true contraceptives.Gamete outcome Shortly after fertilization a zygote develops into a multicellular embryo that in turn develops into a larger organism. In placental mammals this process of gestation occurs inside the reproductive system of the mother of the embryo. Immunity that targets gamete outcome induces abortion of an embryo while it is within its mother's reproductive system.↑ ↑ ↑ ↑ ↑ ↑ ↑
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