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Serotonin – A link between disgust and immunity?
Serotonin – A link between disgust and immunity?

... nearby lymphocytes and modulate immune responses. 5-HT is usually considered a neurotransmitter, which regulates appetite, mood and pain [13]. However, large quantities of this compound exist in the epithelial tissue of the GI tract, airways and skin [12], and this localization might indicate the ro ...
Gastrointestinal helminths may affect host
Gastrointestinal helminths may affect host

... pathogens infecting zebra hosts in ENP; rabies does exist in this system, but there is no evidence that zebra play a role in its dynamics, and there is as yet no evidence of tick-borne pathogens in these ENP hosts Etosha Ecological Institute, EEI, unpublished data; [21]. While ENP zebra have a nearl ...
The immune system
The immune system

... Cell mediated T cells are responsible for. They destroy targets foreing cells by themselves or they „call“ other cells to help them ...
Hepatitis A Post-exposure Prophylaxis
Hepatitis A Post-exposure Prophylaxis

... Protocol provides case and contact management advice for reportable diseases in Ontario. The Hepatitis A virus (HAV) chapter within Appendix A provides post-exposure prophylaxis (PEP) recommendations under the section titled ‘Management of Contacts’.1 The PEP recommendations cite the 2006 Canadian I ...
Antibody-Directed Phototherapy (ADP)
Antibody-Directed Phototherapy (ADP)

... apparent that antibodies, the so-called ‘magic bullets’ first proposed by Erlich at the turn of the 20th century, are themselves non-curative. As an example, trastuzumab (a MAb recognizing human epidermal growth factor receptor-2, (HER2); HerceptinTM) is a successful breast cancer drug which extends ...
Psychoneuroimmunology: Psychological Influences
Psychoneuroimmunology: Psychological Influences

... lymphoid organs like the spleen (Ackerman, Bellinger, Felten, & Felten, 1991). Thus, these transitory changes in the distribution of cells in circulation in peripheral blood (a process called trafficking) probably do not represent a real change in cell numbers. Mouse models suggest the possibility o ...
Background Paper on Yellow Fever Vaccine
Background Paper on Yellow Fever Vaccine

... Since the 1930s when yellow fever vaccine was first used, only 12 cases of yellow fever disease have been identified among vaccine recipients of over 600 million doses of the vaccine administered (Table 2) [19-23]. Of the 12 cases, some (n=3) lacked any laboratory data to confirm them as yellow feve ...
A robust, high-throughput assay to determine the phagocytic activity
A robust, high-throughput assay to determine the phagocytic activity

... secretion, and replaced with 100 μl of 4% paraformaldehyde before plates were analyzed by flow cytometry on a BD LSR II equipped with an HTS plate reader. Samples were mixed thoroughly (100 μl mix volume, repeated three times), prior to analysis of 30 μl of each ...
Molecular detection and characterisation of mumps virus in
Molecular detection and characterisation of mumps virus in

... up to 50% of cases.1 Mumps meningitis may, therefore, be clinically indistinguishable from other types of meningitis, and may be underdiagnosed unless specifically tested for. Data on MuV-associated central nervous system (CNS) infections can provide a reflection of the MuV burden in a population.2 ...
Minnesota Vaccines for Children Separate Stock Clinics: Policies and Procedures Manual 2015
Minnesota Vaccines for Children Separate Stock Clinics: Policies and Procedures Manual 2015

... Center for Disease Control and Prevention’s (CDC) patient download website (www.cdc.gov/vaccines/hcp/vis/mobile.html) during the visit and make sure they have a chance to have their questions answered. Give them a phone number to call in case of any questions or unexpected symptoms after receiving a ...
The potential protective immune responses to synthetic peptides
The potential protective immune responses to synthetic peptides

... Summary. The immunodominant and T-cell epitopes within the fimbrial subunit protein (fimbrilin) of Porphyromonas gingivalis strain 38 1 were analysed by multi-pin peptide synthesis technology. Six regions with immunodominant epitopes within a sequence of 337 amino acids that reacted with the serum o ...
Tetanus Toxoid Adsorbed
Tetanus Toxoid Adsorbed

... Adsorbed manufactured by Sanofi Pasteur Inc. should not be administered more frequently than as recommended for Td vaccines (ie, at 11-12 years of age if at least 5 years have elapsed since the last dose of tetanus and diphtheria toxoid-containing vaccine, and every 10 years thereafter).4 More frequ ...
Avian infectious laryngotracheitis: Virus‐host interactions in relation
Avian infectious laryngotracheitis: Virus‐host interactions in relation

... Genetically-engineered vaccines that are capable of generating immunity, but without the ILTV latent infections induced by conventional modified-live ILT vaccine strains, are now well into development. This paper postulates that, used in conjunction with specific site quarantine and hygiene measures ...
Appendix B - Chickenpox
Appendix B - Chickenpox

... Detection of VZV may be performed in non-routine specimens (e.g., sterile or respiratory sites). Consult with the microbiologist at the PHOL prior to submitting specimen(s). Optimal recovery of VZV is achieved if specimens (e.g., vesicle/lesion fluid or swab) are obtained 2-3 days after rash onset a ...
Memorandum
Memorandum

... wheat, apple leaves, spinach, and radishes -- have been found to contain varying levels of the aforementioned polyamines. Spermine and spermidine (SPERMELENE) is a compound that can be isolated from corn cucumber, oat, and radish leaves and stems,or any other natural source, but may also include any ...
Immune function across generations: integrating mechanism and
Immune function across generations: integrating mechanism and

... environment experienced by mothers. For example, if maternal exposure to a particular pathogen induces antibody production in the mother, the antibodies are transmitted to her offspring, and those offspring mount a more efficient antibody response when challenged with the same pathogen, this could b ...
Monoclonal antibodies in ophthalmology
Monoclonal antibodies in ophthalmology

... cellular and vascular proliferations in the eye. Some of these are also involved in the pathogenesis of different ophthalmologic diseases. One way to regulate these molecules or their receptors is to target them through specific antibodies. Older ways of producing antibodies for targeting such speci ...
ImmunoPursuit - Manchester Immunology Group
ImmunoPursuit - Manchester Immunology Group

... Q. In 1988 which vaccine was combined to replace three separate vaccines in the UK? V1 ...
Therapeutic Protein Immunogenicity Focus Group (TPIFG)
Therapeutic Protein Immunogenicity Focus Group (TPIFG)

... In the area of biomarker identification, complementary protein detection methods add value if the method preserves morphology, provides localization and lends itself to determining levels of protein expression. In addition, simple and reproducible methods of tissue handling and protein immobilizatio ...
Investigation of the humoral and cellular immune responses of
Investigation of the humoral and cellular immune responses of

... of infection by vaccination programs (BERNDT and METHNER, 2001). Vaccination against Salmonella is implemented by law in Germany and applied to control S. typhimurium and S. enteritidis infection in many countries throughout Europa. Previous work has shown, that immunization with live attenuated Sal ...
EFFECT OF RECOMBINANT BOVINE SOMATOROPIN (rbST) ON
EFFECT OF RECOMBINANT BOVINE SOMATOROPIN (rbST) ON

... Egypt, 2- Animal Production Research Institute, Ministry of Agriculture, Dokki, Giza, Egypt SUMMARY To investigate the effects of recombinant bovine somaotropin (rbST) on semen quality and some parameters in seminal plasma of bulls, six Friesian bulls (17.5 to 21.5 month old) were divided into two g ...
5 Clinical Experience with Medical Devices
5 Clinical Experience with Medical Devices

... modified self-antigens, or by tissue destruction from T-lymphocytes or macrophages reacting to endogenous self-antigens. Autoimmune diseases do not necessarily occur as a result of autoimmunity. Agents can bind to tissue or serum proteins and an immune response can be generated against these modifie ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... expressed by phagocytes and dendritic cells [7]. The PRR for fungi includes the Toll-Like Receptor (TLR) and C-type Lectin Receptor (CLR). The fungal cell wall contains polymers such as glucan, chitins and mannoproteins which are recognised by the PRR [10]. The mannoproteins in fungi are recognised ...
handout
handout

... Pathology of circulating immune complexes  Pathogenesis of systemic immune complex-mediated disease (type III hypersensitivity disease) – 3 sequential phases in disease development Fig. 4-11, p.116 Phase I: formation of antigen‐antibody complexes Phase II: immune complex deposition, complement activ ...
Targeting of specific domains of diphtheria toxin by site
Targeting of specific domains of diphtheria toxin by site

... forming a part of the region containing the putative receptor binding domain. All of the anti-peptide antibodies recognized the corresponding peptide, and also reacted with the toxin, specifically with the fragment containing the sequence against which they were raised, confirming the utility of thi ...
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Immunocontraception

In the strictest sense immunocontraception is the use of an animal's immune system to prevent it from fertilizing offspring. More generally the field of immunocontraception includes related technologies that prevent embryonic implantation.Typically immunocontraception involves the administration of a vaccine that induces an adaptive immune response which causes an animal to become temporarily infertile. Contraceptive vaccines have been used in numerous settings for the control of wildlife populations. However, experts in the field believe that major innovations are required before immunocontraception can become a practical form of contraception for human beings.Thus far immunocontraception has focused on mammals exclusively. There are several targets in mammalian sexual reproduction for immune inhibition. They can be organized into three categories.Gamete production Organisms that undergo sexual reproduction must first produce gametes, cells which have half the typical number of chromosomes of the species. Often immunity that prevents gamete production also inhibits secondary sexual characteristics and so has effects similar to castration.Gamete function After gametes are produced in sexual reproduction, two gametes must combine during fertilization to form a zygote, which again has the full typical number of chromosomes of the species. Methods that target gamete function prevent this fertilization from occurring and are true contraceptives.Gamete outcome Shortly after fertilization a zygote develops into a multicellular embryo that in turn develops into a larger organism. In placental mammals this process of gestation occurs inside the reproductive system of the mother of the embryo. Immunity that targets gamete outcome induces abortion of an embryo while it is within its mother's reproductive system.↑ ↑ ↑ ↑ ↑ ↑ ↑
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