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Agenda - Parenteral Drug Association
Agenda - Parenteral Drug Association

... reintroduced into hospitals around Europe.   focus on evaluation of new production  software not up to date, etc.), and methods  Avastin was smuggled into the USA from  technologies, including Single Use Systems  (e.g. insufficient documentation, data  Turkey and turned out to not even contain  (SUS ...
DEPARTMENT OF HEALTH AND HUMAN SERVICES Jul - ~ ~~0;1n
DEPARTMENT OF HEALTH AND HUMAN SERVICES Jul - ~ ~~0;1n

... without any clinically significant impact on the performance of the formulations studied . The comment provided in-vitro data demonstrating comparable recovery of the active ingredient following dissolution in various solution media of effervescent tablets formulated with either PEH or PEB, in the p ...
Findings on “Right to Try” Laws and Pre
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... The first so-called “right to try” law was passed in Colorado in May 2014. As of July 1, 2016, right to try laws have been signed in 31 states, and similar bills are under consideration in an additional eight state legislatures. The right to try movement was instigated by a libertarian think-tank, t ...
Organovo Investor Presentation
Organovo Investor Presentation

... This presentation contains statements about future events and expectations known as “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933, as amended (the “Securities Act”), and Section 21E of the Securities Exchange Act of 1934, as amended (the “Exchange Act”) ...
Mannitol Glass vial Product Sheet (PDF - 10 Ko)
Mannitol Glass vial Product Sheet (PDF - 10 Ko)

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Practical Psychopharmacology in Children and Adolescents

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Patent protection for new uses of known drugs

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FDA`s Efforts to Encourage Biomarker Development and Qualification

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Drug Research and Children

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Canine NSAIDs and Client Education

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Flamel Technologies to be Included in NASDAQ Biotech Index
Flamel Technologies to be Included in NASDAQ Biotech Index

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Overview of Pharma Patent Landscape in India
Overview of Pharma Patent Landscape in India

... The disclaimer has three main functions. First, it specifies the basis upon which the website may be used. In order to use a website, it must be copied, and so this takes the form of a copyright licence. Second, it attempts to limit and exclude (disclaimer) various types of liability that may arise ...
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SPARC Investor Presentation

Drug Discovery and Development
Drug Discovery and Development

The National Association of Health lJnderwriters is an organization of individuals
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... For nearly two years, the Food and Drug Administration has been reviewing whether the allergy drugs Claritin, Allegra and Zyrtec should be switched from prescription drugs to over-thecounter medicines. The FDA, which has sole authority to decide whether drugs should be sold by prescription or over t ...
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Biosimilar

A biosimilar (also known as follow-on biologic or subsequent entry biologic) is a biologic medical product which is a copy of an original product that is manufactured by a different company. Biosimilars are officially approved versions of original ""innovator"" products, and can be manufactured when the original product's patent expires. Reference to the innovator product is an integral component of the approval.Unlike the more common small-molecule drugs, biologics generally exhibit high molecular complexity, and may be quite sensitive to changes in manufacturing processes. Follow-on manufacturers do not have access to the originator's molecular clone and original cell bank, nor to the exact fermentation and purification process, nor to the active drug substance. They do have access to the commercialized innovator product.Drug related authorities such as European Medicines Agency (EMA), Food and Drug Administration (FDA), and Health Canada hold their own guidance on requirements for demonstration of the similar nature of two biological products in terms of safety and efficacy. According to them, analytical studies that demonstrate that the biological product is highly similar to the reference product notwithstanding minor differences in clinically inactive components; animal studies (including the assessment of toxicity); and a clinical study or studies (including the assessment of immunogenicity and pharmacokinetics or pharmacodynamics) that are sufficient to demonstrate safety, purity, and potency in one or more appropriate conditions of use for which the reference product is licensed and intended to be used and for which licensure is sought for the biological product.In case of a monoclonal antibody-containing medicinal product, such as Remsima, extensive physicochemical and biological characterization for it and its reference product Remicade was conducted in order to demonstrate their highly similar properties. Consequently, EMA have granted a marketing authorisation for only a few numbers of biosimilars since 2006 including a monoclonal antibody which is recently approved. Meanwhile, on March 6, 2015, the FDA approved the United States's first biosimilar product, the biosimilar filgrastim Zarxio.
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