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Foundations in Microbiology
Foundations in Microbiology

... Bacteriophages • Bacteriophages – bacterial viruses (phages) • Most widely studied are those that infect Escherichia coli – complex structure, DNA • Multiplication goes through similar stages as animal viruses. • Only the nucleic acid enters the cytoplasm uncoating is not necessary. • Release is a r ...
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... Bacteriophages • Bacteriophages – bacterial viruses (phages) • Most widely studied are those that infect Escherichia coli – complex structure, DNA • Multiplication goes through similar stages as animal viruses. • Only the nucleic acid enters the cytoplasm uncoating is not necessary. • Release is a r ...
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... and no metabolism of their own), and are very small compared to bacteria. They can be crystallised like a chemical, and stored. Viruses consist of a strand of nucleic acid (DNA or RNA) surrounded by a protein sheath called a capsid, built of many identical capsomeres (they have very few genes, so th ...
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...  Permissive or compatible host cells permit viral replication  Nonpermissive host cells do not permit viral replication  Host range may be broad (a number of species) or narrow (one cell type of a single species)  e.g., bacteria, archaea, fungi, protozoa, plants and animals are infected by virus ...
Bacteria / Virus ppt
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S1 Fig
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Bacterial Genetics:Binary Fission, Transduction,Transformation
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... RNA virus 1 Glycoproteins on the viral envelope bind to specific receptor molecules (not shown) on the host cell, promoting viral entry into the cell. ...
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Bacteriophage



A bacteriophage /ˈbækˈtɪər.i.oʊˌfeɪdʒ/ (informally, phage /ˈfeɪdʒ/) is a virus that infects and replicates within a bacterium. The term is derived from ""bacteria"" and the Greek: φαγεῖν (phagein), ""to devour"". Bacteriophages are composed of proteins that encapsulate a DNA or RNA genome, and may have relatively simple or elaborate structures. Their genomes may encode as few as four genes, and as many as hundreds of genes. Phages replicate within the bacterium following the injection of their genome into its cytoplasm. Bacteriophages are among the most common and diverse entities in the biosphere.Phages are widely distributed in locations populated by bacterial hosts, such as soil or the intestines of animals. One of the densest natural sources for phages and other viruses is sea water, where up to 9×108 virions per milliliter have been found in microbial mats at the surface, and up to 70% of marine bacteria may be infected by phages.They have been used for over 90 years as an alternative to antibiotics in the former Soviet Union and Central Europe, as well as in France. They are seen as a possible therapy against multi-drug-resistant strains of many bacteria (see phage therapy).
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