Green Cleaning Notes - Our Essential Oil Family
... exposure to air pollutants indoors can be 2-5 times, and occasionally up to 100 times, higher than outdoor levels. -Office of the Federal Environmental Executive The toxic chemicals in household cleaners are three times more likely to cause cancer than air pollution. -Environmental Protection Agency ...
... exposure to air pollutants indoors can be 2-5 times, and occasionally up to 100 times, higher than outdoor levels. -Office of the Federal Environmental Executive The toxic chemicals in household cleaners are three times more likely to cause cancer than air pollution. -Environmental Protection Agency ...
Hepatotoxicity file
... Liver is Complex Organ Largest organ in body - 1500 g in humans (2% of BW) 25% of cardiac output - 2 L/Minute in 70 kg Human Source of most plasma proteins Interface between food and energy needs ...
... Liver is Complex Organ Largest organ in body - 1500 g in humans (2% of BW) 25% of cardiac output - 2 L/Minute in 70 kg Human Source of most plasma proteins Interface between food and energy needs ...
2_01 Food chemicals Toxicity Text
... premature ageing, cardio-vascular diseases or damage of the immune system. Cancer is initiated if tumour suppressor genes are affected. Damaged DNA of germ cells on the other hand can lead to heritable diseases, malformation or decreased fertility. Genotoxic effects can occur through direct and indi ...
... premature ageing, cardio-vascular diseases or damage of the immune system. Cancer is initiated if tumour suppressor genes are affected. Damaged DNA of germ cells on the other hand can lead to heritable diseases, malformation or decreased fertility. Genotoxic effects can occur through direct and indi ...
Tox-ICK!
... function with or without an accompanying inflammatory response (1). Ocular tissue damage may be a direct result of a drug itself, an accompanying preservative, or from the breakdown of a drug (1). Often, toxic conjunctivitis can be confused with allergic conjunctivitis, especially when considering t ...
... function with or without an accompanying inflammatory response (1). Ocular tissue damage may be a direct result of a drug itself, an accompanying preservative, or from the breakdown of a drug (1). Often, toxic conjunctivitis can be confused with allergic conjunctivitis, especially when considering t ...
Document
... Antidotes: They are classified into four main classes: (A) Chemical antidote: Interfere with the chemical properties of a toxic material converting it to less toxic or less absorbed than the parent compound. ...
... Antidotes: They are classified into four main classes: (A) Chemical antidote: Interfere with the chemical properties of a toxic material converting it to less toxic or less absorbed than the parent compound. ...
Introduction File
... toxicant. An example would be the development of silicosis following a long-term exposure to silica in workplaces such as foundries. Local toxicity—an adverse or undesirable effect that is manifested at the toxicant’s site of contact with the organism. Examples include an acid’s ability to cause bur ...
... toxicant. An example would be the development of silicosis following a long-term exposure to silica in workplaces such as foundries. Local toxicity—an adverse or undesirable effect that is manifested at the toxicant’s site of contact with the organism. Examples include an acid’s ability to cause bur ...
Toxicological Summary for Methyl tert-butyl ether (MTBE) (PDF)
... Note: Even if testing for a specific health effect was not conducted for this chemical, information about that effect might be available from studies conducted for other purposes. Most chemicals have been subject to multiple studies in which researchers identify a dose where no effects were observed ...
... Note: Even if testing for a specific health effect was not conducted for this chemical, information about that effect might be available from studies conducted for other purposes. Most chemicals have been subject to multiple studies in which researchers identify a dose where no effects were observed ...
The No-Observed-Adverse-Effect-Level (NOAEL) in Drug Safety
... experimental point that is without adverse effect" serves us well in general discussions. It does not, however, address the interpretation of risk based on toxicologically relevant effects, nor does it consider the progression of effect with respect to duration and/or dose. It is recommended that, f ...
... experimental point that is without adverse effect" serves us well in general discussions. It does not, however, address the interpretation of risk based on toxicologically relevant effects, nor does it consider the progression of effect with respect to duration and/or dose. It is recommended that, f ...
novi-cleanse - Erichsen Wellness
... enhances the IDEAL PROTEIN DIET because, as we deplete our fat stores, toxins stored in the adipocytes are released. Occasionally the release of these substances may make us feel tired, 'headachy' or even produce rashes. Quite possibly the liver may be stressed because in addition to burning fat and ...
... enhances the IDEAL PROTEIN DIET because, as we deplete our fat stores, toxins stored in the adipocytes are released. Occasionally the release of these substances may make us feel tired, 'headachy' or even produce rashes. Quite possibly the liver may be stressed because in addition to burning fat and ...
Use of Threshold of Concern in determining data requirements for
... Inhalation is the route of exposure Pyrolysis must be considered Additives cannot be assumed to be safe based only on their occurrence as natural components of food (or status as approved food additives) ...
... Inhalation is the route of exposure Pyrolysis must be considered Additives cannot be assumed to be safe based only on their occurrence as natural components of food (or status as approved food additives) ...
stimulants
... Chronic abuse produces a psychosis that resembles schizophrenia and is characterized by paranoia, picking at the skin, preoccupation with one's own thoughts, and auditory and visual hallucinations. Severe depression and violent or erratic behavior are also common among meth ...
... Chronic abuse produces a psychosis that resembles schizophrenia and is characterized by paranoia, picking at the skin, preoccupation with one's own thoughts, and auditory and visual hallucinations. Severe depression and violent or erratic behavior are also common among meth ...
TOXICOLOGY I
... Correlates : exposure and spectrum of effects In general, higher dose more severe the response (Based on observed data from animal, human clinic or cell study) ...
... Correlates : exposure and spectrum of effects In general, higher dose more severe the response (Based on observed data from animal, human clinic or cell study) ...
Toxicology - Uplift Education
... greater than the sum of their individual effects (e.g. 1) The chemical form of the substance alcohol + some antihistamines) 2) How it enters the body 3) The victim’s age, weight, gender, Antagonists – drugs are and condition antagonistic if taking them 4) Time period of exposure together reduces the ...
... greater than the sum of their individual effects (e.g. 1) The chemical form of the substance alcohol + some antihistamines) 2) How it enters the body 3) The victim’s age, weight, gender, Antagonists – drugs are and condition antagonistic if taking them 4) Time period of exposure together reduces the ...
Environmental Health and Toxicology
... • Solutes are freely 自由exchangeable交换 between plasma and the interstitial fluid, thus the concentration of a xenobiotic in tissue is proportional to that of the free xenobiotic in plasma. • The proportionality factor is expressed in terms of an apparent volume of distribution (VD) • Large VD indicat ...
... • Solutes are freely 自由exchangeable交换 between plasma and the interstitial fluid, thus the concentration of a xenobiotic in tissue is proportional to that of the free xenobiotic in plasma. • The proportionality factor is expressed in terms of an apparent volume of distribution (VD) • Large VD indicat ...
Pulmonary Intoxicants
... Ventilator management, PEEP, and oxygen administration might require consultation with a pulmonologist. Fluid hydration may be necessary to treat the hypotension, bradycardia, or impending renal failure. Diuretics such as Lasix are contraindicated because of the hypotension and the noncardiac nature ...
... Ventilator management, PEEP, and oxygen administration might require consultation with a pulmonologist. Fluid hydration may be necessary to treat the hypotension, bradycardia, or impending renal failure. Diuretics such as Lasix are contraindicated because of the hypotension and the noncardiac nature ...
Nutrilite® Vitamin B clinical research
... —Study Goal: Find out how Nutrilite Natural B Complex compares to consumption of folic acid-fortified foods and foods naturally high in folate at increasing plasma folate and decreasing plasma homocysteine levels. —Study Results: After six weeks, plasma folate concentrations increased while homocyst ...
... —Study Goal: Find out how Nutrilite Natural B Complex compares to consumption of folic acid-fortified foods and foods naturally high in folate at increasing plasma folate and decreasing plasma homocysteine levels. —Study Results: After six weeks, plasma folate concentrations increased while homocyst ...
cyanide - World Health Organization
... from the thiocyanate generated through the detoxifying action of rhodanese. It is difficult to interpret human data in view of the difficulty in assessing the actual absorbed dose in humans following acute fatal intoxication and the lack of well-conducted studies on sublethal toxicity. There is a ne ...
... from the thiocyanate generated through the detoxifying action of rhodanese. It is difficult to interpret human data in view of the difficulty in assessing the actual absorbed dose in humans following acute fatal intoxication and the lack of well-conducted studies on sublethal toxicity. There is a ne ...
Toxicological Summary for 4- tert -Octylphenol (PDF)
... 3 for interspecies differences (for toxicodynamics) and 10 for intraspecies variability Critical effect(s): Decreased uterine weights, decreased pup body weight, and increased time to preputial separation Co-critical effect(s): Decreased adult body weight Additivity endpoint(s): Developmental, Femal ...
... 3 for interspecies differences (for toxicodynamics) and 10 for intraspecies variability Critical effect(s): Decreased uterine weights, decreased pup body weight, and increased time to preputial separation Co-critical effect(s): Decreased adult body weight Additivity endpoint(s): Developmental, Femal ...
sample report
... people who do not have industrial exposures to the compound in question, or its "parent", will have a level comparable to the patient; similarly, about fifteen people out of one hundred will have an orange bar for any given analyte. If these findings (yellow or orange bars) are accompanied by classi ...
... people who do not have industrial exposures to the compound in question, or its "parent", will have a level comparable to the patient; similarly, about fifteen people out of one hundred will have an orange bar for any given analyte. If these findings (yellow or orange bars) are accompanied by classi ...
Levels ofToxic Metals in Mice
... believed to be optimum in relation to antioxidative and other beneficial effects of Se. The toxic-metal exposure levels investigated should be similar to those occuring in human populations that are not occupationally exposed. To study interactions between Se and toxic metals at ultralow exposure le ...
... believed to be optimum in relation to antioxidative and other beneficial effects of Se. The toxic-metal exposure levels investigated should be similar to those occuring in human populations that are not occupationally exposed. To study interactions between Se and toxic metals at ultralow exposure le ...
Toxicopathological and biochemical effects of Carbon Tetrachloride
... Pharmacokinetic data suggested that corn oil vehicle resulted in slower absorption , also it is distributed to all major organs as a function of blood flow and fat content of the tissues, with higher concentrations in fat, liver, kidney, brain, lung, bone marrow, and adrenals (3)and (4). The metabol ...
... Pharmacokinetic data suggested that corn oil vehicle resulted in slower absorption , also it is distributed to all major organs as a function of blood flow and fat content of the tissues, with higher concentrations in fat, liver, kidney, brain, lung, bone marrow, and adrenals (3)and (4). The metabol ...
Unit 8: Tobacco, Alcohol, and Drugs
... nerves that control functions such as breathes which means that breathing can slow, become irregular, or stop ...
... nerves that control functions such as breathes which means that breathing can slow, become irregular, or stop ...
Excretion
... Factors Affecting Metabolism (3) • Cirrhosis of the liver is often caused by excessive drinking of alcohol. During the disease process the liver cells are damaged and replaced by connective tissue. If enough cells are killed, the ability of the liver to metabolize toxic substances is dramatically r ...
... Factors Affecting Metabolism (3) • Cirrhosis of the liver is often caused by excessive drinking of alcohol. During the disease process the liver cells are damaged and replaced by connective tissue. If enough cells are killed, the ability of the liver to metabolize toxic substances is dramatically r ...
Fumonisin B1
Fumonisin B1 is the most prevalent member of a family of toxins, known as fumonisins, produced by several species of Fusarium molds, such as Fusarium verticillioides, which occur mainly in maize (corn), wheat and other cereals. Fumonisin B1 contamination of maize has been reported worldwide at mg/kg levels. Human exposure occurs at levels of micrograms to milligrams per day and is greatest in regions where maize products are the dietary staple.Fumonisin B1 is hepatotoxic and nephrotoxic in all animal species tested. The earliest histological change to appear in either the liver or kidney of fumonisin-treated animals is increased apoptosis followed by regenerative cell proliferation. While the acute toxicity of fumonisin is low, it is the known cause of two diseases which occur in domestic animals with rapid onset: equine leukoencephalomalacia and porcine pulmonary oedema syndrome. Both of these diseases involve disturbed sphingolipid metabolism and cardiovascular dysfunction.