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Rapid Selection of Multiple Gene Integrant for the Production of
Rapid Selection of Multiple Gene Integrant for the Production of

... level of HV1 and HV2 was quite different inspite of the same copy number and integration locus. The amino acid and DNA sequence of them are different and this was the only reason of expression level difference. The previous reports about the expression of hirudin variants were studied about only one ...
Divergence Pattern of Duplicate Genes in Protein
Divergence Pattern of Duplicate Genes in Protein

... duplicates follow a symmetric or nearly symmetric divergence pattern supports the random interaction turnover model. This model predicts symmetry in the divergence pattern of the duplicates under the assumption of an equal rate of new partner gains for two copies of one duplicate pair as well as a c ...
From QTLs for enzyme activity to candidate genes in maize
From QTLs for enzyme activity to candidate genes in maize

... glasshouse. DNA was extracted from the leaves of these lines, restricted with various enzymes and hybridized with an Sh2 cDNA probe, after gel separation and Southern blotting. This probe encodes the ADPglucose pyrophosphorylase large subunit (Sh2) which is specifically expressed in endosperm. Sh2 p ...
Gene ORGANizer: linking genes to the organs they
Gene ORGANizer: linking genes to the organs they

... body parts are rare or completely absent (e.g. bone, face, larynx, urethra, teeth, fingers and spinal cord). Second, samples used for expression analyses are usually obtained from specific developmental stages, taken postmortem, and extracted from particular parts of the organ. Thus, the data collec ...
Clustering Method for Repeat Analysis in DNA sequences
Clustering Method for Repeat Analysis in DNA sequences

... sequences have a BLAST E-value less than a UserSpecified Threshold when compared to any sequence in another class  If a class appears in multiple similarity pairs, all these similar classes are merged with the original class ...
PPT
PPT

... sequences have a BLAST E-value less than a UserSpecified Threshold when compared to any sequence in another class  If a class appears in multiple similarity pairs, all these similar classes are merged with the original class ...
Epigenetics: Histone Modification III
Epigenetics: Histone Modification III

... Position-effect variegation (PEV) - Large segments of eukaryotic genomes are made of repetitive sequences that are constitutively heterochromatin - Juxtaposition of a gene to the heterochromatic regions derives PEV. - Spreading heterochromatic features to a nearby gene in a clonal fashion. - The dr ...
Divergence with Gene Flow: Models and Data
Divergence with Gene Flow: Models and Data

... The BDM model invokes two mechanisms for preventing the spread of alleles that have become fixed in one population into the other population. The first is geographic separation, and the second, which kicks in when hybrids are produced, is epistatic incompatibility between alleles that have become fixed ...
Fregene recombination model in detail
Fregene recombination model in detail

... user. Then, within each subregion, a variable number of hotspots (third level) is located given the user-defined hotspot length and the parameters of the Gamma distribution from which the distance between hotspots is sampled. For all three levels, a variable recombination intensity is sampled from a ...
Male-Specific Diseases
Male-Specific Diseases

... and the eyes. The syndrome was named for Dr. Alport who in 1927 described a British family in which many members developed renal disease as well as deafness. He noted that affected men in the family died as a result of their kidney problems, whereas females were less affected and lived until old age ...
Divergence with Gene Flow: Models and Data
Divergence with Gene Flow: Models and Data

Document
Document

... If there are chromosomal number abnormalities, how do they form? • Meiosis: the process of creating sperm or egg from a diploid cell • If there is a mistake when chromosomes are separating, then the resulting sperm or egg will have too many or too few chromosomes. ...
Genome Sequence of an Extremely Halophilic Archaeon
Genome Sequence of an Extremely Halophilic Archaeon

... was the finding of an extremely acidic complement of encoded proteins, which is likely directly related to protein function in its hypersaline (>4M KCl) cytoplasm (11). Calculated isoelectric points (pIs) for predicted proteins showed an average pI of approx 5, a prediction confirmed by proteomic an ...
B = Bit recording gene
B = Bit recording gene

... SAME because bacteria cell wall keeps these gene products internally so that they won’t be mixed up, only the Signaling gene need to be different. Thus different bacteria types can have almost identical genes. This could be a plausible property of a Multi Cell system. ...
Article Parallel Histories of Horizontal Gene
Article Parallel Histories of Horizontal Gene

... The exceptional gene loss observed in Carsonella suggests three possible mechanisms (none of which are mutually exclusive). First, modification of highly conserved cellular processes or selection for multifunctional proteins could have allowed the endosymbiont to dispense with otherwise “essential” ...
Ensembl Genome Browser - molecularevolution.org
Ensembl Genome Browser - molecularevolution.org

... •  Single Nucleotide Polymorphisms (SNPs) •  Deletion-Insertion Polymorphisms (DIPs) •  Short Tandem Repeats (STRs) ...
SGD: Saccharomyces Genome Database.
SGD: Saccharomyces Genome Database.

... time since this first release there have been many updates to this ‘systematic sequence.’ It is anticipated that these updates will continue for some time, albeit at a decreased rate. In addition, sequence annotations must be continually updated to reflect the current knowledge of the genome. The ra ...
Two Cyp19 (P450 Aromatase) Genes on Duplicated Zebrafish
Two Cyp19 (P450 Aromatase) Genes on Duplicated Zebrafish

... branched as expected from the known evolutionary relationships of the species. All fish Cyp19 genes clustered together on the same branch, suggesting that they were all orthologs of the single mammalian Cyp19 gene. The fish branch, however, bifurcated into two subbranches with a high bootstrap value ...
SCOOTER OER Fact Sheet: Dr V Rolfe, December 2010
SCOOTER OER Fact Sheet: Dr V Rolfe, December 2010

... How many chromosomes are there in a human cell? ...
Galaxy Basics: DataSet Manipulation inside of Galaxy
Galaxy Basics: DataSet Manipulation inside of Galaxy

... Rename the dataset to something more meaningful: “All Otoscope Gene IDs” Now lets consolidate the list of Gene IDs to a unique list and get rid of all the duplicates. On a unix command prompt this would be done with commands like ‘uniq’. Use the tool search field to find tools that might help us mak ...
A Molecularly Defined Duplication Set for the X Chromosome of
A Molecularly Defined Duplication Set for the X Chromosome of

... of 408 overlapping P[acman] BAC clones was used to create small duplications (average length 88 kb) covering the 22-Mb sequenced portion of the chromosome. The BAC clones were inserted into an attP docking site on chromosome 3L using FC31 integrase, allowing direct comparison of different transgenes ...
Gene Regulation
Gene Regulation

... Global view of the gene regulatory landscape • The module density varies widely across the genome, with an average of four modules per 100 kb and a maximum of 44 modules per 100-kb window, covering from 0% to 55% of such a region. • As illustrated in the previous figure, some regions are rich in mo ...
Abstract - BioMed Central
Abstract - BioMed Central

... Intron identification is performed by looking at intron PAPs and at splice sites that are positionally conserved. The nodes in splice site graphs are putative donor- and acceptor sites. These are predicted by a PSSM search of generic fungal splice site (Figure 3a-c; see methods section for further d ...
Vertical and horizontal gene transfer in lichens
Vertical and horizontal gene transfer in lichens

... means of self-fertilization and non-self-fertilization. Sexual reproduction of Ascomycota fungi is under the control of mating type (MAT) genes. Heterothallic species (not capable of self-fertilization) have two alleles of those genes: MAT 1-1 and MAT 1-2. Since there is a big difference between the ...
papaya X-specific BACs monoica corresponding
papaya X-specific BACs monoica corresponding

... monoecious, having separate male and female flowers on a single individual, with the lack of sexual dimorphism, signifying the absence of sex chromosomes. The genome size of monoica is 626Mb compared to the 372Mb genome of papaya, signifying expansion in monoica since the divergence of these species ...
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Copy-number variation



Copy-number variations (CNVs)—a form of structural variation—are alterations of the DNA of a genome that results in the cell having an abnormal or, for certain genes, a normal variation in the number of copies of one or more sections of the DNA. CNVs correspond to relatively large regions of the genome that have been deleted (fewer than the normal number) or duplicated (more than the normal number) on certain chromosomes. For example, the chromosome that normally has sections in order as A-B-C-D might instead have sections A-B-C-C-D (a duplication of ""C"") or A-B-D (a deletion of ""C"").This variation accounts for roughly 13% of human genomic DNA and each variation may range from about one kilobase (1,000 nucleotide bases) to several megabases in size. CNVs contrast with single-nucleotide polymorphisms (SNPs), which affect only one single nucleotide base.
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