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GENETICS OF CORONARY ARTERY DISEASE IN FAMILIES
GENETICS OF CORONARY ARTERY DISEASE IN FAMILIES

Learning Targets - Unit 9 DNA, RNA, Proteins, Mutation
Learning Targets - Unit 9 DNA, RNA, Proteins, Mutation

... Learning Targets – Unit 9 DNA, RNA, PROTEIN SYNTHESIS, & MUTATIONS If we, as a class, can begin each statement with, “We can…” then we will have achieved our goal of truly understanding our learning targets. Here are our learning targets for this unit! ...
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... • Augmentation = adding functioning genes into the relevant specialised cells meaning that the protein can be made and the cell will function normally • Killing Specific Cells = making cancer cells express genes producing proteins that make their cells vulnerable to attack by the immune system for t ...
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RNA and Protein

... shift in the frame of the amino acid sequence. Insertion – a gain of a nucleotide in the DNA sequence. ...
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... – How does sequence compare to sequences for proteins of known function? – Use computer to search for functional motifs. • Various proteins that do the same thing have similar structural elements. • Example: transcription factors like lecuine zippers ...
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... By  transfer  of  resistant  bacteria  between  people     By  transfer  of  resistance  genes  between  bacteria  (horizontal  gene  transfer),  by:   – Conjugation  à  Plasmids  are  extrachromosomal  genetic  elements  that  can  carry  g ...
Chapter 12 Powerpoint
Chapter 12 Powerpoint

... Codons: How are they relevant in genetic expression? The order of bases in DNA determines the order of amino acids in a protein. Because there are 20 amino acids present in the proteins, the DNA code must contain 20 code “words”; each word represents a different amino acid. The genetic code is writ ...
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Genetic Technology
Genetic Technology

... DNA Fingerprinting DNA fingerprinting is a kind of genetic analysis. It is famous for solving crimes. At a crime scene, police collect genetic material. Often this is blood or other bodily fluids. In a laboratory, the material is analyzed. Computers compare the DNA fingerprint against those of suspe ...
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Eukaryotic Gene Regulation

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RECONSTRUCTING A “UNIVERSAL TREE”

... Certain genes for DNA replication/repair, transcription/translation… shared by archaea & eukaryotes (but absent in bacteria) ...
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Artificial gene synthesis

Artificial gene synthesis is a method in synthetic biology that is used to create artificial genes in the laboratory. Currently based on solid-phase DNA synthesis, it differs from molecular cloning and polymerase chain reaction (PCR) in that the user does not have to begin with preexisting DNA sequences. Therefore, it is possible to make a completely synthetic double-stranded DNA molecule with no apparent limits on either nucleotide sequence or size. The method has been used to generate functional bacterial or yeast chromosomes containing approximately one million base pairs. Recent research also suggests the possibility of creating novel nucleobase pairs in addition to the two base pairs in nature, which could greatly expand the possibility of expanding the genetic code.Synthesis of the first complete gene, a yeast tRNA, was demonstrated by Har Gobind Khorana and coworkers in 1972. Synthesis of the first peptide- and protein-coding genes was performed in the laboratories of Herbert Boyer and Alexander Markham, respectively.Commercial gene synthesis services are now available from numerous companies worldwide, some of which have built their business model around this task. Current gene synthesis approaches are most often based on a combination of organic chemistry and molecular biological techniques and entire genes may be synthesized ""de novo"", without the need for precursor template DNA. Gene synthesis has become an important tool in many fields of recombinant DNA technology including heterologous gene expression, vaccine development, gene therapy and molecular engineering. The synthesis of nucleic acid sequences is often more economical than classical cloning and mutagenesis procedures.
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