H2N - Department of Computing Science
... • Used to scan for lectin binding domains • Regularly used to predict T-cell epitopes ...
... • Used to scan for lectin binding domains • Regularly used to predict T-cell epitopes ...
Lecture 27
... Carbamoyl phosphate synthetase I is allosterically activated by N-acetylglutamate. N-acetylglutamate is synthesized from glutamate and acetylCoA by N-acetylglutamate synthase, it is hydrolyzed by a specific hydrolase. Rate of urea production is dependent on [N-acetylglutamate]. When aa breakdown rat ...
... Carbamoyl phosphate synthetase I is allosterically activated by N-acetylglutamate. N-acetylglutamate is synthesized from glutamate and acetylCoA by N-acetylglutamate synthase, it is hydrolyzed by a specific hydrolase. Rate of urea production is dependent on [N-acetylglutamate]. When aa breakdown rat ...
Arabidopsis Contains Ancient Classes of Differentially Expressed
... Chua, 1999) examining both transcripts and promoter-driven reporter expression. The AtARP2 gene was expressed in only a small subset of vascular tissue types and pollen, and unlike any conventional actin, AtARP2 was expressed at very low levels. Thus, it seemed possible that AtARP2 and other subclas ...
... Chua, 1999) examining both transcripts and promoter-driven reporter expression. The AtARP2 gene was expressed in only a small subset of vascular tissue types and pollen, and unlike any conventional actin, AtARP2 was expressed at very low levels. Thus, it seemed possible that AtARP2 and other subclas ...
lH NMR characterization of two crambin species
... protons could be assigned assuming that fractions I and II contained single Ser-22/Ile-25 and Pro-22/Leu-25 proteins (apart from the 15% contamination of fraction I as discussed above). In particular, for Be-25 in fraction I the p, y’ and 6 protons resonate at 2.02, 0.78 and 0.92 ppm, respectively, ...
... protons could be assigned assuming that fractions I and II contained single Ser-22/Ile-25 and Pro-22/Leu-25 proteins (apart from the 15% contamination of fraction I as discussed above). In particular, for Be-25 in fraction I the p, y’ and 6 protons resonate at 2.02, 0.78 and 0.92 ppm, respectively, ...
Advanced Computational Structural Genomics
... Individualized medicine- the recognition of individual differences in drug and treatment response, in disease development and progression, in the appearance and thus diagnosis of disease- justifies a much more aggressive approach to utilizing DNA sequence information and the introduction of simulat ...
... Individualized medicine- the recognition of individual differences in drug and treatment response, in disease development and progression, in the appearance and thus diagnosis of disease- justifies a much more aggressive approach to utilizing DNA sequence information and the introduction of simulat ...
Fragmenta Agronomica 2
... reported that increased levels of precipitation were conducive to the accumulation of amino acids in the grain. During the period under analysis, in the second year classified generally as a dry one, in the stage of triticale ripening – in July – the level of precipitations was ca. 23% higher than i ...
... reported that increased levels of precipitation were conducive to the accumulation of amino acids in the grain. During the period under analysis, in the second year classified generally as a dry one, in the stage of triticale ripening – in July – the level of precipitations was ca. 23% higher than i ...
Assembling and Annotating the Draft Human Genome
... Proteins that bind to specific DNA sequences in the promoter region together turn a gene on or off. These proteins are themselves regulated by their own promoters leading to a gene regulatory network with many of the same properties as a neural network. ...
... Proteins that bind to specific DNA sequences in the promoter region together turn a gene on or off. These proteins are themselves regulated by their own promoters leading to a gene regulatory network with many of the same properties as a neural network. ...
Sequences 5` to Translation Start Regulate
... petunia rbcS gene). Schematic illustrations of the 5'-flanking regions of SSU301 and SSU911 are shown in Figure 1. These serve to simplify the region of interest and show the restriction endonuclease sites used in the cloning steps, The three conserved blocks of nucleotide sequence present in SSU301 ...
... petunia rbcS gene). Schematic illustrations of the 5'-flanking regions of SSU301 and SSU911 are shown in Figure 1. These serve to simplify the region of interest and show the restriction endonuclease sites used in the cloning steps, The three conserved blocks of nucleotide sequence present in SSU301 ...
Nutritional Impact on Protein Metabolism of Muscle and
... environmental conditions – eg. excessive stirring of a protein solution in air, exposure to ultraviolet light, elevated temperatures, marked changes in pH, and organic solvents. These procedures lead to alteration of protein structure characterized by loss of solubility and of any biological activit ...
... environmental conditions – eg. excessive stirring of a protein solution in air, exposure to ultraviolet light, elevated temperatures, marked changes in pH, and organic solvents. These procedures lead to alteration of protein structure characterized by loss of solubility and of any biological activit ...
+ O 2
... gp91phox and p22phox. Activation of the complex also involves guanine nucleotide exchange on the GTP-binding protein RAC stimulated by guanine nucleotide exchange factors. Guanine nucleotide exchange on RAC is associated with release of RhoGDI and translocation of RAC from the cytosol to the NOX com ...
... gp91phox and p22phox. Activation of the complex also involves guanine nucleotide exchange on the GTP-binding protein RAC stimulated by guanine nucleotide exchange factors. Guanine nucleotide exchange on RAC is associated with release of RhoGDI and translocation of RAC from the cytosol to the NOX com ...
Genetics and genomics of behavioral and psychiatric disorders
... Stimulated by these findings, several association studies between MAOA and various psychiatric conditions have been carried out, but most of them were inconclusive. Notably, one study of a birth cohort of 1037 male children, whose development was followed to adulthood, considered an environmental fa ...
... Stimulated by these findings, several association studies between MAOA and various psychiatric conditions have been carried out, but most of them were inconclusive. Notably, one study of a birth cohort of 1037 male children, whose development was followed to adulthood, considered an environmental fa ...
Facts and Observations in Relation to the X
... varying from person to person (the basis of forensic identification) due to a rate of mutation higher than SNPs. So for example at marker DXS10075 an individual could have allele (variant) repeats of TAGA from 16 to 21 (each X marker having slightly different properties). 3) LINE (long interspersed ...
... varying from person to person (the basis of forensic identification) due to a rate of mutation higher than SNPs. So for example at marker DXS10075 an individual could have allele (variant) repeats of TAGA from 16 to 21 (each X marker having slightly different properties). 3) LINE (long interspersed ...
Renal Fanconi syndrome: taking a proximal look at the nephron
... studied the five generation family described by Tolaymat et al. [27]. Reassessment of the clinical phenotype confirmed the original observations made by Tolaymat et al. Moreover, it demonstrated normal age-appropriate GFR in all affected family members, including the, by then, 74-year-old matriarch. T ...
... studied the five generation family described by Tolaymat et al. [27]. Reassessment of the clinical phenotype confirmed the original observations made by Tolaymat et al. Moreover, it demonstrated normal age-appropriate GFR in all affected family members, including the, by then, 74-year-old matriarch. T ...
Slide 1
... has the common amino-terminal pentapeptide and hence similar activity to gastrin II. The same sequence occurs in all CCKs, although only CCK8 is shown. Y* indicates that a sulfate group is attached to that tyrosine in each of these peptides. See Appendix C for an explanation of the letters coding fo ...
... has the common amino-terminal pentapeptide and hence similar activity to gastrin II. The same sequence occurs in all CCKs, although only CCK8 is shown. Y* indicates that a sulfate group is attached to that tyrosine in each of these peptides. See Appendix C for an explanation of the letters coding fo ...
Kreitman review on positive selection
... time, so that the most recent common ancestor of two alleles can predate speciation events. Neutral variants that are tightly linked to a site under selection will also be maintained by this selection, albeit passively, and the age of the balanced polymorphism will promote neutral divergence at link ...
... time, so that the most recent common ancestor of two alleles can predate speciation events. Neutral variants that are tightly linked to a site under selection will also be maintained by this selection, albeit passively, and the age of the balanced polymorphism will promote neutral divergence at link ...
Detection of Free Radicals
... gp91phox and p22phox. Activation of the complex also involves guanine nucleotide exchange on the GTP-binding protein RAC stimulated by guanine nucleotide exchange factors. Guanine nucleotide exchange on RAC is associated with release of RhoGDI and translocation of RAC from the cytosol to the NOX com ...
... gp91phox and p22phox. Activation of the complex also involves guanine nucleotide exchange on the GTP-binding protein RAC stimulated by guanine nucleotide exchange factors. Guanine nucleotide exchange on RAC is associated with release of RhoGDI and translocation of RAC from the cytosol to the NOX com ...
The Jumping SHOX Gene—Crossover in the Pseudoautosomal
... pseudoautosomal. The SHOX gene in the normal situation is present in two functional copies. In fact, one might consider PAR1 as a very small extra pair of autosomes (11), except that segregation in autosomes is independent of sex. Here we describe three families in which an abnormality in PAR1 segre ...
... pseudoautosomal. The SHOX gene in the normal situation is present in two functional copies. In fact, one might consider PAR1 as a very small extra pair of autosomes (11), except that segregation in autosomes is independent of sex. Here we describe three families in which an abnormality in PAR1 segre ...
Promoter identification and analysis of key glycosphingolipid
... transcription initiation region had five alternative splicing sites and two promoters, but other genes in the glycosphingolipid biosynthesis-globo series pathway were not studied (Gan et al., 2016). Moreover, other regions of the two promoters can affect gene expression; thus, further studies are re ...
... transcription initiation region had five alternative splicing sites and two promoters, but other genes in the glycosphingolipid biosynthesis-globo series pathway were not studied (Gan et al., 2016). Moreover, other regions of the two promoters can affect gene expression; thus, further studies are re ...
Dicyclohexylcarbodiimide-binding proteins related to the short circuit
... the stacked configuration evolved more clearly. Furthermore, labeling of other proteins than those in the 20 - 30-kDa range was nearly reduced to the background level. From these and our earlier results (Jahns et al., 1988) it is conceivable that covalent binding of (cHxN),C to the 20-kDa and/or 24- ...
... the stacked configuration evolved more clearly. Furthermore, labeling of other proteins than those in the 20 - 30-kDa range was nearly reduced to the background level. From these and our earlier results (Jahns et al., 1988) it is conceivable that covalent binding of (cHxN),C to the 20-kDa and/or 24- ...
WHAT IS A GENE? - Electronic Scholarly Publishing
... for study of gene properties. However, a limitation is imposed on the usefulness of this material, by reason of the fact that even the frequent changes occurring naturally in these genes cannot be controlled experimentally. Muller’s discovery that x-rays can induce changes in genes opened up a wide ...
... for study of gene properties. However, a limitation is imposed on the usefulness of this material, by reason of the fact that even the frequent changes occurring naturally in these genes cannot be controlled experimentally. Muller’s discovery that x-rays can induce changes in genes opened up a wide ...
Cloning of PCR products into TOPO TA vectors
... regulatory sequences and the coding information for the first 146 amino acids of the βgalactosidase (LacZ) gene of E. coli. The polypeptide encoded by this region of lacZ is also known as the α subunit of β-galactosidase and is the basis for an easy assay to determine whether a foreign DNA fragment ...
... regulatory sequences and the coding information for the first 146 amino acids of the βgalactosidase (LacZ) gene of E. coli. The polypeptide encoded by this region of lacZ is also known as the α subunit of β-galactosidase and is the basis for an easy assay to determine whether a foreign DNA fragment ...
A nuclear matrix-associated high molecular mass nuclear antigen
... decreased substantially at 1.5 and 2.5 hours after release from the aphidicolin block at the G1/S boundary, but then increased again and reached a high level at 4.5 hours (Fig. 2B). Flow cytometry on PI-stained cells indicated that the 1.5- and 2.5 hour points corresponded to mid S and late S/G2 pha ...
... decreased substantially at 1.5 and 2.5 hours after release from the aphidicolin block at the G1/S boundary, but then increased again and reached a high level at 4.5 hours (Fig. 2B). Flow cytometry on PI-stained cells indicated that the 1.5- and 2.5 hour points corresponded to mid S and late S/G2 pha ...
Clinical Genetic Basis of Tooth Agenesis (PDF Available)
... nucleotides with the insertion of 288 foreign nucleotides [21]. Some of the unique reported mutations, like frame-shift, insertion, missense, nonsense and deletions of entire PAX9 gene.[22] These mutations were identified in the DNA-binding paired domain of PAX9 gene, resulting in a disturbed regula ...
... nucleotides with the insertion of 288 foreign nucleotides [21]. Some of the unique reported mutations, like frame-shift, insertion, missense, nonsense and deletions of entire PAX9 gene.[22] These mutations were identified in the DNA-binding paired domain of PAX9 gene, resulting in a disturbed regula ...
Point mutation
A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.