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The mapping of linear B-cell epitope regions in desmoglein 1 and 3
The mapping of linear B-cell epitope regions in desmoglein 1 and 3

... recognition [17]. Hacker-Foegen et al. identified a conformational epitope in the first 87 Nterminal residues of the Dsg1 protein using domain-swapped proteins and smaller recombinant protein fragments [29]. Bhol et al. identified two antigenic protein fragments BOS1 (aa50-79) and BOS6 (aa200-229) f ...
ADVANTAGES OF PORCINE BLOOD PLASMA AS A COMPONENT
ADVANTAGES OF PORCINE BLOOD PLASMA AS A COMPONENT

... The nitrogen compounds present in the plasma are not limited to the known proteins (albumins, globulins, and fibrinogen), since plasma also contains amino acids, ammonia, the products of purine and pyrimidine nucleotide metabolism, etc., and this can account for the discrepancy between the total pro ...
Analysis of Selection, Mutation and Recombination in Genetic
Analysis of Selection, Mutation and Recombination in Genetic

... De ne a genetic representation of the problem Create an initial population P (0)P= x01 : : : x0N Compute the average tness F = Ni F(xi)=N. Assign each individual the normalized tness value F(xti)=F Assign each xi a probability p(xi t) proportional to its normalized tness. Using this distributi ...
Annex 1
Annex 1

... subsequently to the application, which gives a detailed disclosure of the nucleotide and/or amino acid sequences and other available information; (ii) sequences which are included are any unbranched sequences of four or more amino acids or unbranched sequences of ten or more nucleotides. Branched se ...
Saccharomyces Genome Database.
Saccharomyces Genome Database.

... Registry form (http:l/genome-www4.stanford.edu/cgi-binlSGDIregistry/geneRegistry). In 1994 Robert Mortimer transferred the task of maintaining the nomenclature orS. cerevisiae genes, the Gene Name Registry, to SGD. Yeast researchers can reserve a gene name or register a published gene name by submit ...
[ 19] Saccharomyces Genome Database - SGD-Wiki
[ 19] Saccharomyces Genome Database - SGD-Wiki

... Registry form (http:l/genome-www4.stanford.edu/cgi-binlSGDIregistry/geneRegistry). In 1994 Robert Mortimer transferred the task of maintaining the nomenclature orS. cerevisiae genes, the Gene Name Registry, to SGD. Yeast researchers can reserve a gene name or register a published gene name by submit ...
lecture - Department of Molecular & Cell Biology
lecture - Department of Molecular & Cell Biology

... led him to propose that two "hits" or mutagenic events were necessary for retinoblastoma development. Retinoblastoma occurs sporadically in most cases, but in some families it displays autosomal dominant inheritance. In an individual with the inherited form of the disease, Knudson proposed that the ...
The human Y chromosome: the biological role of a “functional
The human Y chromosome: the biological role of a “functional

... been solved through inactivation of one X chromosome in females. In spite of the limited make-up of genes, different transcription units or families of closely related transcription units have been identified in the NRY region during the past decade (see [12–14, 2, 15–18]). Recently, Lahn and Page [3 ...
Summary SUMMARY Chapter 2a Comparison of
Summary SUMMARY Chapter 2a Comparison of

... hydroxylamine oxidoreductase genes for analyzing NitrosomonoLS spp. diversity > Amongst the 22 samples, 6 samples DnrA, DnrB, CETP, DN, N and PF showed higher nitrite production. > Presence of AOB in the 6 enriched samples was confirmed by amplifying amoA gene. > Twelve kinds of isolated red colored ...
Extrachromosomal DNA Transformationof Caenorhabditis elegans
Extrachromosomal DNA Transformationof Caenorhabditis elegans

... amount of pBR322 hybridization expected for each worm DNA preparation if the plasmid sequences were present in one copy per genome (see Table 2). The percentage of transformed worms in each population was used to derive the copy number per genome per transformant. It should be noted that the copy nu ...
View/Open - Indiana University
View/Open - Indiana University

Dwarfism in Cattle - Fancher Love Ranch
Dwarfism in Cattle - Fancher Love Ranch

... I expected to finish this article a few days after I began researching, but it’s been very, very hard to understand the subject of genetics and its ties to dwarfism. I hope that I’ve been able to relay this information without making too many mistakes; please feel free to correct me. I am not a scie ...
Lab Recap: Miniprep (MP)
Lab Recap: Miniprep (MP)

... plasmid DNA yield). Note that different labs (universities, companies, etc.) have different miniprep  procedures. If you get to work at a lab, it’s good to get acquainted with its miniprep procedures. During  the lab, we may refer to your “miniprep” as whatever is in the contents of the tubes you ar ...
genes is conserved among species related to
genes is conserved among species related to

... interacts with avian epithelial cells. O n the other hand, Greene & Klaenhammer (1994) reported that the chemical removal of the S-layer of L. aciduphilw did not influence the r'n vitra adhesion of bacteria of this strain to Caco-2 cells. Toba ef al. (1995) reported that the S-layer of an L. crirpat ...
Mechanisms Underlying the Evolution and Maintenance of
Mechanisms Underlying the Evolution and Maintenance of

... evolution (Brown, Wensink, and Jordan 1972; Zimmer et al. 1980; Arnheim 1983) or birth-and-death evolution models (Hughes and Nei 1989; Ota and Nei 1994; Nei, Gu, and Sitnikova 1997; Gu and Nei 1999; Rooney, Piontkivska, and Nei 2002). In the latter model, gene duplication gives rise to new genes, s ...
Adaptation from standing genetic variation
Adaptation from standing genetic variation

... selective sweep than that expected from a new mutation. Compared with new mutations, neutral or weakly deleterious alleles maintained as standing variation have a longer history in the population before becoming advantageous. One effect of this extra time is that it provides greater opportunity for ...
EXTENSIONS AND DEVIATIONS OF MENDELIAN INHERITANCE
EXTENSIONS AND DEVIATIONS OF MENDELIAN INHERITANCE

... Overdominance is related to a common mating strategy used by animal and plant breeders Two different highly inbred strains are crossed „ The hybrids may display traits superior to both parents „ This phenomenon is termed hybrid vigor or heterosis Heterosis is used to improve quantitative traits such ...
Determining the epitope dominance on the capsid of a SAT2 fmdv by mutational analysis, P.A.Opperman
Determining the epitope dominance on the capsid of a SAT2 fmdv by mutational analysis, P.A.Opperman

... Determine the role of known and predicted epitopes of SAT2 viruses and to present evidence of epitope dominance within the SAT2 serotype of FMDV ...
Uracil in DNA – occurrence, consequences and repair
Uracil in DNA – occurrence, consequences and repair

... DNA glycosylases, which may have different functional roles. The steps downstream of the initial glycosylase step may also differ, depending on origin and localisation of uracil, the specific DNA glycosylase involved, and timing in the cell cycle. In this review the emphasis will be on the enzymes t ...
Dias nummer 1
Dias nummer 1

... acid. Human influenza preferentially binds to α-2,6 sialic acid-galactose-linkages whereas avian influenza preferentially binds to α-2,3 sialic acid-galactose-linkages (3). So far there has not been an effective inter-human transmission which potentially can lead to a pandemic (1, 4).To obtain inter ...
Epigenetic Mechanisms of Gene Regulation
Epigenetic Mechanisms of Gene Regulation

... In mammals, DNA methylation patterns are not randomly distributed throughout the genome, but rather methylated DNA is localized to discrete regions of the genome enriched in repetitive DNA and transposable elements, imprinted domains, and the inactive X chromosome in females. ^^'^^ In these regions, ...
30 Synthesis of Glycosides, Lactose, Glycoproteins and Glycolipids
30 Synthesis of Glycosides, Lactose, Glycoproteins and Glycolipids

... UDP-galactose are used for glycosyltransferase reactions in many systems. Lactose, for example, is synthesized from UDP-galactose and glucose in the mammary gland. UDP-glucose also can be oxidized to form UDP-glucuronate, which is used to form glucuronide derivatives of bilirubin and xenobiotic comp ...
- Wiley Online Library
- Wiley Online Library

... Both XZ and YX nuclear types transformed ...
The Ames Test
The Ames Test

... identifying potential human carcinogens without waiting for long-lived mammals to develop cancer. In this assay, mutant strains of the bacteria Salmonella tymphimurium (S. typhimurium) will be used. These haploid bacteria already contain particular mutations in the gene encoding an enzyme used to sy ...
INTRODUCTION
INTRODUCTION

... 50% of unsuccessful impregnations are due to the loss of zygote by genetic causes (genetic, chromosomal and genomic mutations). If the development of the embryo didn’t stop at an early stage, the phenotypic effects were formed in 3 variants, depending on the involved gene and the nature of mutation ...
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Point mutation



A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.
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