Acetyl-coenzyme A carboxylase – an attractive enzyme for biotechnolo
... FAS and, therefore, both enzyme activity and gene transcription are increased under anabolic conditions. The mitochondria-associated ACC2 is mainly involved in the regulation of fat beta-oxidation pathway by inhibiting carnitine palmitoyl transferase-1 (CPT-1) which controls the long chain fatty acy ...
... FAS and, therefore, both enzyme activity and gene transcription are increased under anabolic conditions. The mitochondria-associated ACC2 is mainly involved in the regulation of fat beta-oxidation pathway by inhibiting carnitine palmitoyl transferase-1 (CPT-1) which controls the long chain fatty acy ...
Unverified Color Pink-eye dilution Ukraine
... Gene and mutation According to the inheritance pattern, the “pink-‐eye” phenotype is caused by a single gene. We have started to search for this gene and for the causative mutation, ...
... Gene and mutation According to the inheritance pattern, the “pink-‐eye” phenotype is caused by a single gene. We have started to search for this gene and for the causative mutation, ...
The Chicken (Gallus gallus) Z Chromosome Contains at Least Three
... Birds have female heterogamety with Z and W sex chromosomes. These evolved from different autosomal precursor chromosomes than the mammalian X and Y. However, previous work has suggested that the pattern and process of sex chromosome evolution show many similarities across distantly related organism ...
... Birds have female heterogamety with Z and W sex chromosomes. These evolved from different autosomal precursor chromosomes than the mammalian X and Y. However, previous work has suggested that the pattern and process of sex chromosome evolution show many similarities across distantly related organism ...
Handout - 7 - Misc - Topics for discussion at June 2016
... Historically, ACnc was used as a placeholder for the Property of Ordinal codes. A few years ago, we started transitioning to “Pr” as the Property for observations reported simply based on whether the analyte is present or not without being determined by a cut off value, and “Threshold” as the proper ...
... Historically, ACnc was used as a placeholder for the Property of Ordinal codes. A few years ago, we started transitioning to “Pr” as the Property for observations reported simply based on whether the analyte is present or not without being determined by a cut off value, and “Threshold” as the proper ...
Large-scale analysis of Influenza A virus nucleoprotein sequence
... Conservation analysis The conservation of amino acid residues was obtained and projected onto the protein structure using the ConSurf 2010 server (Ashkenazy et al., 2010; Celniker et al., 2013; Landau et al., 2005). The ConSurf algorithm takes into account the evolutionary relationships between prot ...
... Conservation analysis The conservation of amino acid residues was obtained and projected onto the protein structure using the ConSurf 2010 server (Ashkenazy et al., 2010; Celniker et al., 2013; Landau et al., 2005). The ConSurf algorithm takes into account the evolutionary relationships between prot ...
Jolly Good Knowledge from the Seven Seas Monday,October 9
... eyepiece, body tube, nosepiece, Objective lenses, diaphragm, light ...
... eyepiece, body tube, nosepiece, Objective lenses, diaphragm, light ...
Lesson 3: Can you taste PTC?
... phism (SNP) to Predict Bi er Tas ng Ability Kit, was developed by the Dolan DNA Learning Center and is available through Carolina Biological (h p://www.carolina.com/human‐gene cs/using‐a‐ single‐nucleo de‐polymorphism‐snp‐to‐predict‐bi er‐tas ng‐ability‐kit/FAM_211376.pr? catId=&mCat=&sCat=&ssCat=& ...
... phism (SNP) to Predict Bi er Tas ng Ability Kit, was developed by the Dolan DNA Learning Center and is available through Carolina Biological (h p://www.carolina.com/human‐gene cs/using‐a‐ single‐nucleo de‐polymorphism‐snp‐to‐predict‐bi er‐tas ng‐ability‐kit/FAM_211376.pr? catId=&mCat=&sCat=&ssCat=& ...
Supplementary Figure Legends (doc 52K)
... these hydrocarbons in incubations with the corresponding unlabelled substrates as measured by HPLC (naphthalene and phenanthrene) or GCMS (n-hexadecane) (squares). (a) phenanthrene; (b) naphthalene; (c) n-hexadecane. The endpoint for these SIP incubations was determined to be 5 days. Each data point ...
... these hydrocarbons in incubations with the corresponding unlabelled substrates as measured by HPLC (naphthalene and phenanthrene) or GCMS (n-hexadecane) (squares). (a) phenanthrene; (b) naphthalene; (c) n-hexadecane. The endpoint for these SIP incubations was determined to be 5 days. Each data point ...
SBT-production - Webarchiv ETHZ / Webarchive ETH
... 1. Flux balance analysis (FBA) max (growth rate) s.t. metabolite balances available substrates ...
... 1. Flux balance analysis (FBA) max (growth rate) s.t. metabolite balances available substrates ...
Lecture 27
... Glu synthesized by Glutamate synthase. Occurs only in microorganisms, plants, and lower animals. Converts -ketoglutarate and ammonia from glutamine to glutamate. Reductive amination requires electrons from either NADPH or ferredoxin (organism dependent). NADPH-dependent glutamine synthase from Azos ...
... Glu synthesized by Glutamate synthase. Occurs only in microorganisms, plants, and lower animals. Converts -ketoglutarate and ammonia from glutamine to glutamate. Reductive amination requires electrons from either NADPH or ferredoxin (organism dependent). NADPH-dependent glutamine synthase from Azos ...
Enzymes in Food Technology
... • The operons of enteric bacteria quickly switch over to lactose metabolism, and the resulting in-vivo fermentation produces copious amounts of gas (a mixture of hydrogen, carbon dioxid, and methane). • This, in turn, may cause a range of abdominal symptoms, including stomach cramps, nausea, bloatin ...
... • The operons of enteric bacteria quickly switch over to lactose metabolism, and the resulting in-vivo fermentation produces copious amounts of gas (a mixture of hydrogen, carbon dioxid, and methane). • This, in turn, may cause a range of abdominal symptoms, including stomach cramps, nausea, bloatin ...
Chapter 15 Notes
... Because males have only one locus, the terms homozygous and heterozygous lack meaning for describing their X-linked genes. o The term hemizygous is used in such cases. The chance of a female inheriting a double dose of the mutant allele is much less than the chance of a male inheriting a single dose ...
... Because males have only one locus, the terms homozygous and heterozygous lack meaning for describing their X-linked genes. o The term hemizygous is used in such cases. The chance of a female inheriting a double dose of the mutant allele is much less than the chance of a male inheriting a single dose ...
Sequence variation in the dihydrofolate reductase
... 11 amino acid polymorphisms in TR . No amino acid replacements occur in regions that are important for the enzymatic activity of these proteins, but some polymorphisms occur in sites previously assumed to be invariant. The sequences from both genes cluster in four major groups, a result that is not ...
... 11 amino acid polymorphisms in TR . No amino acid replacements occur in regions that are important for the enzymatic activity of these proteins, but some polymorphisms occur in sites previously assumed to be invariant. The sequences from both genes cluster in four major groups, a result that is not ...
Ch 15 summary - OHS General Biology
... Because males have only one locus, the terms homozygous and heterozygous lack meaning for describing their X-linked genes. o The term hemizygous is used in such cases. The chance of a female inheriting a double dose of the mutant allele is much less than the chance of a male inheriting a single dose ...
... Because males have only one locus, the terms homozygous and heterozygous lack meaning for describing their X-linked genes. o The term hemizygous is used in such cases. The chance of a female inheriting a double dose of the mutant allele is much less than the chance of a male inheriting a single dose ...
Chapter 15 Outline- The Chromosomal Basis of Inheritance
... the Barr body occurs randomly and independently in each embryonic cells present at the time of X inactivation. o As a consequence, females consist of a mosaic of two types of cells, some with an active paternal X chromosome and others with an active maternal X chromosome. o After an X chromosome is ...
... the Barr body occurs randomly and independently in each embryonic cells present at the time of X inactivation. o As a consequence, females consist of a mosaic of two types of cells, some with an active paternal X chromosome and others with an active maternal X chromosome. o After an X chromosome is ...
HUMAN GENETICS GROUP
... recessive model in order to search for new susceptibility genes. Among the candidates, we have found a splice-site deleterious mutation in a gene that is involved in the maintenance of genomic stability and DNA repair pathways. This excellent candidate is currently undergoing functional studies in o ...
... recessive model in order to search for new susceptibility genes. Among the candidates, we have found a splice-site deleterious mutation in a gene that is involved in the maintenance of genomic stability and DNA repair pathways. This excellent candidate is currently undergoing functional studies in o ...
Molecular cloning and tissue distribution of the Toll
... includes a putative signal peptide (residues 1-19), an extracellular domain (residues 133-706) consisting of LRRs flanked by cysteine-rich motifs, a single-pass transmembrane portion (residues 713-735), and a cytoplasmic TIR domain (residues 766-904). Twelve potential N-linked glycosylation sites, w ...
... includes a putative signal peptide (residues 1-19), an extracellular domain (residues 133-706) consisting of LRRs flanked by cysteine-rich motifs, a single-pass transmembrane portion (residues 713-735), and a cytoplasmic TIR domain (residues 766-904). Twelve potential N-linked glycosylation sites, w ...
PDF
... replication and results in an estimated 15 copies per cell (Durland and Helinski, 1990). Though trfA is not carried by the fosmid, it can be provided in trans; notably, the commercial E. coli strain EPI300 (Epicentre Biotechnologies) carries trfA under the control of an inducible promoter that is ad ...
... replication and results in an estimated 15 copies per cell (Durland and Helinski, 1990). Though trfA is not carried by the fosmid, it can be provided in trans; notably, the commercial E. coli strain EPI300 (Epicentre Biotechnologies) carries trfA under the control of an inducible promoter that is ad ...
Titin mutation segregates with hereditary
... In 2001, we described an autosomal dominant myopathy characterized by neuromuscular ventilatory failure in ambulant patients. Here we describe the underlying genetic basis for the disorder, and we define the neuromuscular, respiratory and radiological phenotype in a study of 31 mutation carriers fol ...
... In 2001, we described an autosomal dominant myopathy characterized by neuromuscular ventilatory failure in ambulant patients. Here we describe the underlying genetic basis for the disorder, and we define the neuromuscular, respiratory and radiological phenotype in a study of 31 mutation carriers fol ...
Lecture 36 - Lipid Metabolism 2
... Acetyl CoA carboxylase - catalyzes the commitment step in fatty acid synthesis using a biotin-mediated reaction mechanism that carboxylates acetyl-CoA to form the C3 compound malonyl-CoA.. Fatty acid synthase - this large multi-functional enzyme is responsible for catalyzing a series of reactions th ...
... Acetyl CoA carboxylase - catalyzes the commitment step in fatty acid synthesis using a biotin-mediated reaction mechanism that carboxylates acetyl-CoA to form the C3 compound malonyl-CoA.. Fatty acid synthase - this large multi-functional enzyme is responsible for catalyzing a series of reactions th ...
Biotechnology Explorer - Bio-Rad
... With the pGLO transformation kit, students use a simple procedure to transform bacteria with a gene that codes for Green Fluorescent Protein (GFP). The real-life source of this gene is the bioluminescent jellyfish Aequorea victoria, and GFP causes the jellyfish to fluoresce and glow in the dark. Fol ...
... With the pGLO transformation kit, students use a simple procedure to transform bacteria with a gene that codes for Green Fluorescent Protein (GFP). The real-life source of this gene is the bioluminescent jellyfish Aequorea victoria, and GFP causes the jellyfish to fluoresce and glow in the dark. Fol ...
Coenzyme A and Acyl Carrier Protein
... At least five families of acyl CoA synthetases are known in humans with specificities for fatty acids in different chain-length groups, i.e. short-chain (2-3 carbons), medium-chain (4-12 carbons), long-chain (12-22 carbons), so-called ‘bubble-gum’ (14-24 carbons) and very-long-chain (18-26 or more c ...
... At least five families of acyl CoA synthetases are known in humans with specificities for fatty acids in different chain-length groups, i.e. short-chain (2-3 carbons), medium-chain (4-12 carbons), long-chain (12-22 carbons), so-called ‘bubble-gum’ (14-24 carbons) and very-long-chain (18-26 or more c ...
Chapter 6 Pichia pastoris
... (Saccharomyces cerevisiae and Pichia pastoris), mammalian cells, amphibian oocytes (Xenopus laevis), insect cells and bacteria (Escherichia coli). Plant cells are useful as hosts if mutants are available (Holton et al., 1993), but in many cases the distinction from resident activities may present a ...
... (Saccharomyces cerevisiae and Pichia pastoris), mammalian cells, amphibian oocytes (Xenopus laevis), insect cells and bacteria (Escherichia coli). Plant cells are useful as hosts if mutants are available (Holton et al., 1993), but in many cases the distinction from resident activities may present a ...
Point mutation
A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.