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Meiosis
Meiosis

... In the beginning of telophase I, each half of the cell has a haploid set of chromosomes; each chromosome still consists of two sister chromatids Cytokinesis usually occurs simultaneously, forming two haploid daughter cells In animal cells, a cleavage furrow forms; in plant cells, a cell plate forms ...
On the maintenance of allozyme and inversion polymorphisms in
On the maintenance of allozyme and inversion polymorphisms in

... be responsiblefor the obsen'edfluctuationsin genetic composition of the greenhouse population. No sharp distinction can be made between functional and chromosomal of the Ádlt and aGpdh loci as causefor the non-randomassociationof alleles associations observedin this population.Moreover,non-randomass ...
Editing Multiple Alignments
Editing Multiple Alignments

... Secondary structure elements Hydrophobic regions, polar residues ...
Tetrahydrobiopterin and its functions
Tetrahydrobiopterin and its functions

... Tetrahydrobiopterin (BH4) is essential for diverse processes and is ubiquitously present in all tissues of higher organisms. It is well established as essential cofactor for various enzyme activities to activate dioxygen, and for less defined functions at the cellular level. The latter function of B ...
16S rRNA characterization of Bacillus strain and its
16S rRNA characterization of Bacillus strain and its

RTS™ pIVEX E. coli His-tag 2nd Generation Vector Set Manual
RTS™ pIVEX E. coli His-tag 2nd Generation Vector Set Manual

... Include one of these sites into the forward primer. OR eliminate the restriction site by mutation (e.g. conservative codon exchange [1, 2]). OR prepare a cloning fragment by limited digestion if the restriction site of your choice is present in the gene [1, 2]. ...
Studying the pathogenesis of renal disease in cystinosis
Studying the pathogenesis of renal disease in cystinosis

... • Discovery of cystinosin in 1998 opened a new chapter of diseases caused by defects of lysosomal transport proteins. • New data indicate that the expression of cystinosin is not restricted to the lysosomal membrane. Ongoing studies will identify new functions and regulators of cystinosin activity  ...
Chapter 12
Chapter 12

... If the heterozygote has greatest fitness, it is said to be overdominant; if it has lowest fitness, it is said to be underdominant. The disadvantageous allele is lower in frequency and may be entirely eliminated. That is called purifying or negative selection. The relationship between phenotype and ...
Connections between mRNA 3( end processing and transcription
Connections between mRNA 3( end processing and transcription

... CTD phosphorylation by Ctk1. Although cleavage and polyadenylation are normal in strains mutated for these factors, a striking defect in termination is seen [32]. The data strongly support a mechanism in which Rat1 attacks the new 50 end generated by cleavage. As the polymerase continues transcrib ...
A Modified Genetic Algorithm for Matching Building Sets with the
A Modified Genetic Algorithm for Matching Building Sets with the

... footprint. These coordinates are stored as absolute positions in a database of polygon features, represented in the coordinate system of the scene. From this information, we calculate the HoF between any two buildings. As the size of the search area increases, the number of possible building pairs g ...
A natural recessive resistance gene against potato virus
A natural recessive resistance gene against potato virus

... (PVY), corresponds to a eukaryotic initiation factor 4E (eIF4E) gene. RFLP analysis on the PVY-susceptible and resistant pepper cultivars, using an eIF4E cDNA from tobacco as probe, revealed perfect map cosegregation between a polymorphism in the eIF4E gene and the pvr2 alleles, pvr21 (resistant to ...
Study of the Effects of High-Energy Proton Beams
Study of the Effects of High-Energy Proton Beams

... irradiated with protons at 0, 13, 23, 46 and 93 Gy were serially diluted with the ratio of 1:10,000 and 1:1,000, respectively. Aliquots of 0.2 mL the bacteria medium were plated on LB agar plates. After 24 h incubation, the colony formed units (CFU) in each plate were evaluated. The survival rate wa ...
Ben-Hur1 pdf
Ben-Hur1 pdf

... lyases, isomerases and ligases. The remaining numbers have meanings that are particular to each category. Consider for example, the oxidoreductases (EC number starting with 1), which involve reactions in which hydrogen or oxygen atoms or electrons are transferred between molecules. In these enzymes, ...
Sequence Alignment
Sequence Alignment

... • exactly the same Amino Acid or Nucleotide in the same position Sequence similarity • substitutions with similar chemical properties Sequence homology • general term that indicates evolutionary relatedness among sequences • sequences are homologous if they are derived from a common ancestral ...
milova_032405 - Microarray Facility
milova_032405 - Microarray Facility

...  R statistical package  S-PLUS. Insightful Kate Milova ...
Identification and quantification of mycotoxigenic fungi
Identification and quantification of mycotoxigenic fungi

... metabolites are being considered [47]. The levels of detection for mycotoxins are extremely sensitive and now concentrations of as low as 1015 (106 is the mg kg1 level) can be conceived of with NMR and mass spectroscopy. Furthermore, it is possible to determine if all the genes of a pathway can b ...
Production and characterization of murine models of classic and
Production and characterization of murine models of classic and

... short-term outcome of liver transplantation is encouraging, long-term effects of this approach are not known. However, these patients are now required to take immunosuppressant drugs for the rest of their lives, often with undesirable side effects. Moreover, the cost associated with liver transplant ...
Effects of Natural Selection on Interpopulation Divergence
Effects of Natural Selection on Interpopulation Divergence

... protein structure by causing changes to functionally important amino acid residues or on gene expression by altering regulation (Kimura and Ohta 1974; Nei 1987). Estimation of gene diversity (heterozygosity) at 1442 SNP sites in an ethnically diverse sample of humans revealed consistently reduced ge ...
Evolutionary Forces in Shaping the Codon and Amino Acid Usages
Evolutionary Forces in Shaping the Codon and Amino Acid Usages

... that at least 15-20% of insects live in this manner (28). This relationship may play great role for evolutionary success of insects, because it may help the insects to take new imbalanced food, which also helpful for maintain ecological balance (29). The bacterial transmission occurs vertically from ...
Article PDF
Article PDF

... piston (set to 1 atm), with a total simulation time of 200 ns (∼205 000 CPU hours using 2.3 GHz Intel EM64T processors). 2.2. Verification of Convergence. It was shown previously that 50 ns was needed to equilibrate ions near DNA chains.22,23 To verify the validity of this assumption in our simulati ...
Specific oligonucleotide primers for detection of endoglucanase
Specific oligonucleotide primers for detection of endoglucanase

The evolution of life cycles with haploid and diploid phases
The evolution of life cycles with haploid and diploid phases

... population, who then gain both the advantages of fewer mutations and of masking. Consequently, theoretical models of this phenomenon have led to the conclusion that predominantly haploid life cycles are favored if (1) sex is rare, (2) recombination is rare, (3) selfing is common, or (4) assortative ...
Sequence and Tissue Distribution of a Second Protein of Hepatic
Sequence and Tissue Distribution of a Second Protein of Hepatic

New methods for tightly regulated gene expression and
New methods for tightly regulated gene expression and

A Study of Free Amino Acids and of Glutamine
A Study of Free Amino Acids and of Glutamine

... from dietary sources alone. As a result, a portion of the nitrogen needed for tumor growth is drawn from the protein stores of the host (10). Under these circumstances, it would seem likely that the amino acid metabolism of the host would be dis turbed. Information on this point, however, has not be ...
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Point mutation



A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.
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