Forche et al. 2008 PLoS Biology
... The parasexual cycle of C. albicans, as currently envisaged, is shown in Figure 1A. Note that no meiotic program has been observed in C. albicans, despite the presence of many genes in the genome whose homologues function specifically in meiosis in other fungi [18]. However, C. albicans strains have ...
... The parasexual cycle of C. albicans, as currently envisaged, is shown in Figure 1A. Note that no meiotic program has been observed in C. albicans, despite the presence of many genes in the genome whose homologues function specifically in meiosis in other fungi [18]. However, C. albicans strains have ...
The Parasexual Cycle in Candida albicans Provides an
... The parasexual cycle of C. albicans, as currently envisaged, is shown in Figure 1A. Note that no meiotic program has been observed in C. albicans, despite the presence of many genes in the genome whose homologues function specifically in meiosis in other fungi [18]. However, C. albicans strains have ...
... The parasexual cycle of C. albicans, as currently envisaged, is shown in Figure 1A. Note that no meiotic program has been observed in C. albicans, despite the presence of many genes in the genome whose homologues function specifically in meiosis in other fungi [18]. However, C. albicans strains have ...
The shikimate pathway in apicomplexan parasites: Implications for
... gondii DAHPS is significantly larger than the previously reported type II enzymes. This is caused by numerous insertions into the protein sequence (21). To the best of our knowledge no biochemical information of an apicomplexan DAHPS is presently available except that DAHPS activity was observed in ...
... gondii DAHPS is significantly larger than the previously reported type II enzymes. This is caused by numerous insertions into the protein sequence (21). To the best of our knowledge no biochemical information of an apicomplexan DAHPS is presently available except that DAHPS activity was observed in ...
New variants of the tet(M) gene in Clostridium
... that tet(M)1, tet(M)3, tet(M)5 and tet(M)6 were preceded by a complete leader peptide sequence, whereas this region was partially deleted in the region upstream of tet(M)2 and tet(M)4 for the loss of 124 bp (data not shown). The residual transcriptional attenuation activity could be maintained in th ...
... that tet(M)1, tet(M)3, tet(M)5 and tet(M)6 were preceded by a complete leader peptide sequence, whereas this region was partially deleted in the region upstream of tet(M)2 and tet(M)4 for the loss of 124 bp (data not shown). The residual transcriptional attenuation activity could be maintained in th ...
The Role of N- and C-terminal Amino Acids to
... This thesis is an investigation of the role of the prosegment (PS) of pepsinogen in the binding, refolding and inhibition of pepsin. Native pepsin (Np) is irreversibly denatured, and folds to a stable, non-native state under refolding conditions, termed refolded pepsin (Rp) (Dee and Yada 2010). When ...
... This thesis is an investigation of the role of the prosegment (PS) of pepsinogen in the binding, refolding and inhibition of pepsin. Native pepsin (Np) is irreversibly denatured, and folds to a stable, non-native state under refolding conditions, termed refolded pepsin (Rp) (Dee and Yada 2010). When ...
Single-Amino Acid Substitutions Alter the Specificity and Affinity of
... A ConserVed Lys or Arg Residue in PDZ Domains of PSD95 Is a Key Determinant for Interaction with nNOS. PSD95 contains three tandem PDZ domains that have distinct binding specificities. The second PDZ domain, which has been shown to interact with the PDZ domain of nNOS (11, 12), has a Lys residue in ...
... A ConserVed Lys or Arg Residue in PDZ Domains of PSD95 Is a Key Determinant for Interaction with nNOS. PSD95 contains three tandem PDZ domains that have distinct binding specificities. The second PDZ domain, which has been shown to interact with the PDZ domain of nNOS (11, 12), has a Lys residue in ...
Searching for Compact Hierarchical Structures in DNA by means of
... The exponential growth of available DNA sequences in recent years is having a fruitful clash with the deep questions underlying information science. Brooks identified in 2003 recent development in biology as the necessary pressure to finally develop a long-time needed quantification of structural infor ...
... The exponential growth of available DNA sequences in recent years is having a fruitful clash with the deep questions underlying information science. Brooks identified in 2003 recent development in biology as the necessary pressure to finally develop a long-time needed quantification of structural infor ...
MyGene.info Documentation
... • “ensembl”, “refseq” and “accession” contains associations between RNA and protein • Better mapping between Ensembl and Entrez gene IDs • JSON structure slightly changed • and more bugfixes You can read more details about this version on our ‘blog http://mygene.info/mygene-info-v3-is-out‘_ Migratio ...
... • “ensembl”, “refseq” and “accession” contains associations between RNA and protein • Better mapping between Ensembl and Entrez gene IDs • JSON structure slightly changed • and more bugfixes You can read more details about this version on our ‘blog http://mygene.info/mygene-info-v3-is-out‘_ Migratio ...
Designing synthetic MLPA probes - MRC
... corresponding NG_sequence here: http://www.ncbi.nlm.nih.gov/refseq/rsg/browse/. N.b. NG_sequences also include intronic sequences. Nucleotide. The combination of LPO and RPO. DNA oligonucleotide which, when annealed to a complementary DNA sequence, can be used as starting point for extension by a po ...
... corresponding NG_sequence here: http://www.ncbi.nlm.nih.gov/refseq/rsg/browse/. N.b. NG_sequences also include intronic sequences. Nucleotide. The combination of LPO and RPO. DNA oligonucleotide which, when annealed to a complementary DNA sequence, can be used as starting point for extension by a po ...
CHRYSAORA QUINQUECIRRHA) Research Article
... collagens properly according to their characteristics, the industrial use of jellyfish collagen could be extended in various fields. Collagen-based biomaterials are of the utmost importance for biomedical aspects and regenerative medicine. Because of its superior biocompatibility and low immunogenic ...
... collagens properly according to their characteristics, the industrial use of jellyfish collagen could be extended in various fields. Collagen-based biomaterials are of the utmost importance for biomedical aspects and regenerative medicine. Because of its superior biocompatibility and low immunogenic ...
Nutrient transport into germinating Trichoderma
... growth of yeasts. Thus, H+-ATPase activity may be developmentally regulated. In this work we studied the development of nutrient transport during T. atroviride conidia germination. Precursors of macromolecules and phospholipids were chosen as nutrients. The results confirm that H+-ATPase activity is ...
... growth of yeasts. Thus, H+-ATPase activity may be developmentally regulated. In this work we studied the development of nutrient transport during T. atroviride conidia germination. Precursors of macromolecules and phospholipids were chosen as nutrients. The results confirm that H+-ATPase activity is ...
Fulltext PDF - Indian Academy of Sciences
... We report novel findings on the cytogenetic location, functional complexity and maternal and germline roles of the stambh A locus of Drosophila melanogaster. stmA is localized to polytene bands 44D1.2 on 2R. stmA mutations are of two types: temperature-sensitive (ts) adult and larval paralytic or un ...
... We report novel findings on the cytogenetic location, functional complexity and maternal and germline roles of the stambh A locus of Drosophila melanogaster. stmA is localized to polytene bands 44D1.2 on 2R. stmA mutations are of two types: temperature-sensitive (ts) adult and larval paralytic or un ...
Malic acid production by Aspergillus oryzae
... Among those are manganese [64], zinc and iron [138]. Besides those external factors, it was reported that the cell morphology has an influence as well. Concerning the question whether pellet or filamentous growth promotes citric acid production the results are contradictory and probably strain speci ...
... Among those are manganese [64], zinc and iron [138]. Besides those external factors, it was reported that the cell morphology has an influence as well. Concerning the question whether pellet or filamentous growth promotes citric acid production the results are contradictory and probably strain speci ...
Organization and Integration of Large
... basis for in silico growth simulations of wall-less bacteria. Unraveling the principles governing energy metabolism and adaptive capabilities upon gene deletion facilitates the development of engineering tools and dynamic models for metabolic sub-systems. Our results highlight the impact of the redu ...
... basis for in silico growth simulations of wall-less bacteria. Unraveling the principles governing energy metabolism and adaptive capabilities upon gene deletion facilitates the development of engineering tools and dynamic models for metabolic sub-systems. Our results highlight the impact of the redu ...
Bartonella chomelii sp. nov., isolated from French domestic cattle
... bacteria, often piliated or flagellated. They are intracellular parasites of red blood cells and endothelial cells. In reservoir hosts, Bartonella infections usually result in asymptomatic bacteraemia. This bacteraemic phase is required for the long-term perpetuation of the bacterium, allowing its t ...
... bacteria, often piliated or flagellated. They are intracellular parasites of red blood cells and endothelial cells. In reservoir hosts, Bartonella infections usually result in asymptomatic bacteraemia. This bacteraemic phase is required for the long-term perpetuation of the bacterium, allowing its t ...
Organization and Integration of Large-scale Datasets for
... basis for in silico growth simulations of wall-less bacteria. Unraveling the principles governing energy metabolism and adaptive capabilities upon gene deletion facilitates the development of engineering tools and dynamic models for metabolic sub-systems. Our results highlight the impact of the redu ...
... basis for in silico growth simulations of wall-less bacteria. Unraveling the principles governing energy metabolism and adaptive capabilities upon gene deletion facilitates the development of engineering tools and dynamic models for metabolic sub-systems. Our results highlight the impact of the redu ...
5 The structure and function of membrane proteins
... powerful, desktop computers with performance equivalent to the previous generation of supercomputers. Many experimental techniques relied on the codevelopment of computer hardware but software has also played a vital role in protein biochemistry. We can now search databases comparing proteins at the ...
... powerful, desktop computers with performance equivalent to the previous generation of supercomputers. Many experimental techniques relied on the codevelopment of computer hardware but software has also played a vital role in protein biochemistry. We can now search databases comparing proteins at the ...
Hydrolyzed Source Proteins as Used in Cosmetics
... Most of the hydrolyzed proteins in this assessment are found in the foods we consume daily, and the daily exposure from food use would result in a much larger systemic dose than that resulting from use in cosmetic products. These ingredients would be safe if absorbed into the body. Consequently, sin ...
... Most of the hydrolyzed proteins in this assessment are found in the foods we consume daily, and the daily exposure from food use would result in a much larger systemic dose than that resulting from use in cosmetic products. These ingredients would be safe if absorbed into the body. Consequently, sin ...
Gene Section GAST (gastrin) Atlas of Genetics and Cytogenetics
... GACAGA site via the activating signal cointegrator 1 (ASC-1) complex, whereas prostaglandins, resulting from the activation of COX2, target the Myc-associated zinc finger protein (MAZ site via the small GTPase RhoA to stimulate PAI-2 expression in adjacent CCK2 receptor-negative cells. ...
... GACAGA site via the activating signal cointegrator 1 (ASC-1) complex, whereas prostaglandins, resulting from the activation of COX2, target the Myc-associated zinc finger protein (MAZ site via the small GTPase RhoA to stimulate PAI-2 expression in adjacent CCK2 receptor-negative cells. ...
Ret/PTC3 is the most frequent form of gene rearrangement
... papillary thyroid carcinomas only for ret/PTC1 rearrangements and found no rearrangement; Ishizaka et al. (1991) found one ret/PTC1 rearrangement among 11 carcinomas, and Wajjwalku et al. (1992) found only one such alteration among 38 carcinomas. On the basis of those observations, RET gene rearrang ...
... papillary thyroid carcinomas only for ret/PTC1 rearrangements and found no rearrangement; Ishizaka et al. (1991) found one ret/PTC1 rearrangement among 11 carcinomas, and Wajjwalku et al. (1992) found only one such alteration among 38 carcinomas. On the basis of those observations, RET gene rearrang ...
Case Study: BPTI
... now take a closer look at the three BPTI-like proteins and then compare their 3D structures and amino acid sequences with that of BPTI. First, load the coordinates of the three BPTI-like proteins by opening the following PDB files: human-APPI-1AAP.pdb, snake-venom-CI-1JC6.pdb and sea-anemone-1SHP.pd ...
... now take a closer look at the three BPTI-like proteins and then compare their 3D structures and amino acid sequences with that of BPTI. First, load the coordinates of the three BPTI-like proteins by opening the following PDB files: human-APPI-1AAP.pdb, snake-venom-CI-1JC6.pdb and sea-anemone-1SHP.pd ...
Horizontal gene transfer from flowering plants to Gnetum
... nosperm-type and angiosperm-type nad1 intron 2 sequences was possible because they possess unique characteristics. The gymnosperm-type nad1 intron 2 in Gnetum is characterized by 37–80 base pairs inserted before the GTGCG motif that is typical of the start of group II introns (Tables 3 and 4 and Fig ...
... nosperm-type and angiosperm-type nad1 intron 2 sequences was possible because they possess unique characteristics. The gymnosperm-type nad1 intron 2 in Gnetum is characterized by 37–80 base pairs inserted before the GTGCG motif that is typical of the start of group II introns (Tables 3 and 4 and Fig ...
A Comparative Study on the Recovery of EcoRI Endonuclease from
... (pSCC2) overproducing strains using similar protocols, and the enzyme yields were compared. In plasmid pPG430, genes encoding EcoRI endonuclease and methylase are oriented under the control of the lac promoter13 , whereas in plasmid pSCC2, they are placed under the control of PL3 . a) Enzyme Purific ...
... (pSCC2) overproducing strains using similar protocols, and the enzyme yields were compared. In plasmid pPG430, genes encoding EcoRI endonuclease and methylase are oriented under the control of the lac promoter13 , whereas in plasmid pSCC2, they are placed under the control of PL3 . a) Enzyme Purific ...
Point mutation
A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.