Two enhancer regions in the mouse En-2 locus
... CNS, En-2 is expressed in cells surrounding the developing pituitary (Davis et al., 1988, 1991). In addition, immunohistochemical analysis using a polyclonal antiserum (aEnhb-1) that detects both En-1 and En-2 protein has shown that one or both genes are expressed in presumptive myoblasts within the ...
... CNS, En-2 is expressed in cells surrounding the developing pituitary (Davis et al., 1988, 1991). In addition, immunohistochemical analysis using a polyclonal antiserum (aEnhb-1) that detects both En-1 and En-2 protein has shown that one or both genes are expressed in presumptive myoblasts within the ...
from Scolopendra subspinipes mutilans
... was determined by using snake venom such as that of Bothrops neuwiedii, which has a known molecular weight of 13,364 Da [7]. In this study, pharmacopuncture extracted from the body part of centipedes was studied to determine how effective it was. We separated the head from the body of the centipede, ...
... was determined by using snake venom such as that of Bothrops neuwiedii, which has a known molecular weight of 13,364 Da [7]. In this study, pharmacopuncture extracted from the body part of centipedes was studied to determine how effective it was. We separated the head from the body of the centipede, ...
Exome sequencing as a tool for Mendelian disease gene discovery
... nonsense single-base substitutions or small insertion– deletions (that is, indels), are predicted to have functional consequences and/or to be deleterious14. As such, the exome represents a highly enriched subset of the genome in which to search for variants with large effect sizes. Defining the exo ...
... nonsense single-base substitutions or small insertion– deletions (that is, indels), are predicted to have functional consequences and/or to be deleterious14. As such, the exome represents a highly enriched subset of the genome in which to search for variants with large effect sizes. Defining the exo ...
Genetic Analysis of HNF4A Polymorphisms in Caucasian
... alternative splicing of these exons results in at least nine isoforms of the gene. The transcription of three of these isoforms is driven by an alternate promoter known as P2, which is located ⬃45.5 kb upstream of the P1 promoter (11,12). Recent studies suggest that although both promoters function ...
... alternative splicing of these exons results in at least nine isoforms of the gene. The transcription of three of these isoforms is driven by an alternate promoter known as P2, which is located ⬃45.5 kb upstream of the P1 promoter (11,12). Recent studies suggest that although both promoters function ...
Biopathways Representation and Simulation on Hybrid Functional
... twice as large as that of dimers). But it is neither intuitive nor natural at all. It may be obvious that this feature of HPN/HDN is a severe drawback in modeling biopathways. On the other hand, some favorable features have been also introduced in Petri net theory. In addition to normal arc explaine ...
... twice as large as that of dimers). But it is neither intuitive nor natural at all. It may be obvious that this feature of HPN/HDN is a severe drawback in modeling biopathways. On the other hand, some favorable features have been also introduced in Petri net theory. In addition to normal arc explaine ...
Chapter 13 Meiosis
... sexual life cycles contributes to evolution • Mutations (changes in an organism’s DNA) are the original source of genetic diversity • Mutations create different versions of genes called alleles • Reshuffling of alleles during sexual reproduction produces genetic variation ...
... sexual life cycles contributes to evolution • Mutations (changes in an organism’s DNA) are the original source of genetic diversity • Mutations create different versions of genes called alleles • Reshuffling of alleles during sexual reproduction produces genetic variation ...
—1— User Guide © Copyright 2009 Robert C. Edgar, all rights
... (inter) once for the entire genome, then the intra-chromosome simulator (intra) once for each chromosome. This process is called a cycle. The output from one cycle can be used as input to another cycle. It is generally better to run many short cycles rather than one or a few long cycles as longer cy ...
... (inter) once for the entire genome, then the intra-chromosome simulator (intra) once for each chromosome. This process is called a cycle. The output from one cycle can be used as input to another cycle. It is generally better to run many short cycles rather than one or a few long cycles as longer cy ...
Enzymes–II
... If, however, the effect of increasing temperature (in terms of three ill-demarcated categories of low, medium and high) on enzyme activity is studied (Fig. 17−6), it may be observed that the initial velocity of the reaction (given by the shape of the curves at t = 0) steadily increases with temperau ...
... If, however, the effect of increasing temperature (in terms of three ill-demarcated categories of low, medium and high) on enzyme activity is studied (Fig. 17−6), it may be observed that the initial velocity of the reaction (given by the shape of the curves at t = 0) steadily increases with temperau ...
Galactose Metabolism in Saccharomyces cerevisiae
... resulting in an overall free energy change (G) close to zero and, therefore, an equilibrium constant close to one. Thus the presence of an unstructured region in the binding site between two proteins can result in a highly specific, but readily reversible interaction (Dyson and Wright 2002). This r ...
... resulting in an overall free energy change (G) close to zero and, therefore, an equilibrium constant close to one. Thus the presence of an unstructured region in the binding site between two proteins can result in a highly specific, but readily reversible interaction (Dyson and Wright 2002). This r ...
Nucleus-Encoded Genes for Plastid
... Plastids are the organelles of plants and algae that house photosynthesis and many other biochemical pathways. Plastids contain a small genome, but most of their proteins are encoded in the nucleus and posttranslationally targeted to the organelle. When plants and algae lose photosynthesis, they vir ...
... Plastids are the organelles of plants and algae that house photosynthesis and many other biochemical pathways. Plastids contain a small genome, but most of their proteins are encoded in the nucleus and posttranslationally targeted to the organelle. When plants and algae lose photosynthesis, they vir ...
- Philsci-Archive
... on finding criteria that distinguish causal from non-causal relationships. There is, however, another important project, also belonging to the philosophy of causation that has received less attention, at least among philosophers. This is the project of elucidating and understanding the basis for var ...
... on finding criteria that distinguish causal from non-causal relationships. There is, however, another important project, also belonging to the philosophy of causation that has received less attention, at least among philosophers. This is the project of elucidating and understanding the basis for var ...
PDF
... in such a strikingly Drosophila-like pattern during a process that is strongly reminiscent of gastrulation contradicts expectations based upon the classical distinction between diploblastic and triploblastic animals and indicates that snail expression was already associated with creation of a new in ...
... in such a strikingly Drosophila-like pattern during a process that is strongly reminiscent of gastrulation contradicts expectations based upon the classical distinction between diploblastic and triploblastic animals and indicates that snail expression was already associated with creation of a new in ...
Molybdenum Complexes with Amino Acids as
... A sharp band at 1643.35cm-1 in the ligand due to C=O vibration was also shifted to lower frequency (1620.21-1604.77) in the complexes. Moreover, the appearance of additional weak bands in the region 462-493 and 732.95-740.67 cm-1 which were attributed to ν(M-O) and ν(M-N), respectively, confirmed th ...
... A sharp band at 1643.35cm-1 in the ligand due to C=O vibration was also shifted to lower frequency (1620.21-1604.77) in the complexes. Moreover, the appearance of additional weak bands in the region 462-493 and 732.95-740.67 cm-1 which were attributed to ν(M-O) and ν(M-N), respectively, confirmed th ...
On the Uniqueness of the Standard Genetic Code
... genetic codes. This staggering number is beyond any imaginable astronomical number, the total count of electrons in the universe being well below this number. Note, however, that this calculation tacitly ignores the evolution of the SGC. If we assume two sets of 32 complementary triplets where each ...
... genetic codes. This staggering number is beyond any imaginable astronomical number, the total count of electrons in the universe being well below this number. Note, however, that this calculation tacitly ignores the evolution of the SGC. If we assume two sets of 32 complementary triplets where each ...
Scientist finds the gene that determines major sensitivity to bitter taste
... taste sensitivity. Variation in the ability to taste PTC was discovered by Fox (1931). Supplementation of the standard test using quinine in the intermediate cases was suggested by Kalmus (1958). Ability to taste has been thought to be dominant. Reddy and Rao (1989) reexamined the genetics of PTC ta ...
... taste sensitivity. Variation in the ability to taste PTC was discovered by Fox (1931). Supplementation of the standard test using quinine in the intermediate cases was suggested by Kalmus (1958). Ability to taste has been thought to be dominant. Reddy and Rao (1989) reexamined the genetics of PTC ta ...
Engineering of steroid biotransformation in rhodococcus van
... KSTD2. The kstD gene, encoding the KSTD1 isoenzyme, was cloned on a 6 kb BglII genomic fragment isolated from a partial (BglII) genomic library of R. erythropolis strain SQ1 using a degenerate kstD oligonucleotide as a probe in Southern analysis. The nucleotide sequence of the kstD oligonucleotide w ...
... KSTD2. The kstD gene, encoding the KSTD1 isoenzyme, was cloned on a 6 kb BglII genomic fragment isolated from a partial (BglII) genomic library of R. erythropolis strain SQ1 using a degenerate kstD oligonucleotide as a probe in Southern analysis. The nucleotide sequence of the kstD oligonucleotide w ...
Towards the development of standardized methods for comparison
... Motivation: Pairwise alignment of protein structures is a fundamental task in structural bioinformatics. There are numerous computer programs in the public domain that produce alignments for a given pair of protein structures, but the results obtained by the various programs generally differ substan ...
... Motivation: Pairwise alignment of protein structures is a fundamental task in structural bioinformatics. There are numerous computer programs in the public domain that produce alignments for a given pair of protein structures, but the results obtained by the various programs generally differ substan ...
Meiosis
... gametes contained two sets of chromosomes, the zygote resulting from their union would have four sets of chromosomes. The number of chromosomes would continue to double with each new generation, which could result in the extinction of the species. However, this does not usually happen; the number of ...
... gametes contained two sets of chromosomes, the zygote resulting from their union would have four sets of chromosomes. The number of chromosomes would continue to double with each new generation, which could result in the extinction of the species. However, this does not usually happen; the number of ...
TITLE : BLAST
... The graphical overview show the distribution of blast hits on query sequence. The numbered red bar at the top of the figure 5.1 is represent the query sequence while the number attached to the red bar is query coordinates. The alignment scores are defined by using color key. As can be seen from figu ...
... The graphical overview show the distribution of blast hits on query sequence. The numbered red bar at the top of the figure 5.1 is represent the query sequence while the number attached to the red bar is query coordinates. The alignment scores are defined by using color key. As can be seen from figu ...
PowerPoint 프레젠테이션
... RNAi (RNA interference) is a phenomenon that small double-stranded RNA (Referred as small interference RNA or siRNA) can knock down the expression of its corresponding gene. RNAi has been observed in plant, C.elegans and Drosophila long time ago. It was until recently that RNAi was discovered to wor ...
... RNAi (RNA interference) is a phenomenon that small double-stranded RNA (Referred as small interference RNA or siRNA) can knock down the expression of its corresponding gene. RNAi has been observed in plant, C.elegans and Drosophila long time ago. It was until recently that RNAi was discovered to wor ...
Analysis of TALE superclass homeobox genes
... in the DNA-binding helix 3 of the TALE homeodomains is in many cases a small, non-polar residue. In the IRO class it is an alanine, in the PBC class it is a glycine, in most of the other genes it is an isoleucine. Position 50 is very critical for the DNA binding specificity of the homeodomain (for e ...
... in the DNA-binding helix 3 of the TALE homeodomains is in many cases a small, non-polar residue. In the IRO class it is an alanine, in the PBC class it is a glycine, in most of the other genes it is an isoleucine. Position 50 is very critical for the DNA binding specificity of the homeodomain (for e ...
- Wiley Online Library
... We assess the use to which bioinformatics in the form of bacterial genome sequences, functional gene probes and the protein sequence databases can be applied to hypotheses about obligate autotrophy in eubacteria. Obligate methanotrophy and obligate autotrophy among the chemo- and photo-lithotrophic ...
... We assess the use to which bioinformatics in the form of bacterial genome sequences, functional gene probes and the protein sequence databases can be applied to hypotheses about obligate autotrophy in eubacteria. Obligate methanotrophy and obligate autotrophy among the chemo- and photo-lithotrophic ...
02 Cholesterol Metabolism2012-03-18 01:50617 KB
... Most important animal steroid Maintains membrane fluidity Insulating effect on nerve fibres Cholesterol is the parent molecule for – Bile acids and bile salts – Steroid hormones – Vitamin D3 ...
... Most important animal steroid Maintains membrane fluidity Insulating effect on nerve fibres Cholesterol is the parent molecule for – Bile acids and bile salts – Steroid hormones – Vitamin D3 ...
Using Transcriptional Control To Increase Titers of Secreted
... The type III secretion system (T3SS) encoded at the Salmonella pathogenicity island 1 (SPI-1) locus secretes protein directly from the cytosol to the culture media in a concerted, one-step process, bypassing the periplasm. While this approach is attractive for heterologous protein production, produc ...
... The type III secretion system (T3SS) encoded at the Salmonella pathogenicity island 1 (SPI-1) locus secretes protein directly from the cytosol to the culture media in a concerted, one-step process, bypassing the periplasm. While this approach is attractive for heterologous protein production, produc ...
Agarose Gel Electrophoresis
... gradually removed, causing a concomitant decrease in the mobility of the DNA molecule. This occurs until a critical free-dye concentration is reached where no more superhelical turns remain (usually between 0.1 to 0.5 µg/ml). As still more ethidium bromide is bound, positive superhelical turns are g ...
... gradually removed, causing a concomitant decrease in the mobility of the DNA molecule. This occurs until a critical free-dye concentration is reached where no more superhelical turns remain (usually between 0.1 to 0.5 µg/ml). As still more ethidium bromide is bound, positive superhelical turns are g ...
Point mutation
A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.