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Bacterial Genomics
Bacterial Genomics

... display a mutational bias towards deletions among small indels ...
Molecular parasitology in the 21st Century
Molecular parasitology in the 21st Century

... elements (sequences of DNA that can move around to different positions within the genome) such as mariner have been successful. The transpos‑ able element mariner has also been successfully used in T. brucei. Chemical mutagenesis in Leishmania has led to the identification of important genes involve ...
Section 13-1 Ghanging the Living World
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... To maintain the desired characteristics of a Iine ...
mutation - Carol Eunmi LEE - University of Wisconsin–Madison
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... • Metabolic-rate hypothesis. Mutation rate that is due to endogenous or exogenous mutagens, such as oxygen radicals. This hypothesis argues that groups with higher metabolic rates produce more free radicals, which leads to greater DNA damage and faster mutation and evolutionary rates. • DNA repai ...
Lecture PPT - Carol Eunmi LEE - University of Wisconsin–Madison
Lecture PPT - Carol Eunmi LEE - University of Wisconsin–Madison

... • Metabolic-rate hypothesis. Mutation rate that is due to endogenous or exogenous mutagens, such as oxygen radicals. This hypothesis argues that groups with higher metabolic rates produce more free radicals, which leads to greater DNA damage and faster mutation and evolutionary rates. • DNA repair h ...
4.04 Workfile
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... Is DNA forensic analysis reliable? Guilty as charged. Kathryn Holmes, Department of Justice What if you came home one day and discovered your iPod was not in its usual place? Instead of resting on your nightstand, you found it tossed on the floor with a big scratch on the screen. First, you would ex ...
Lecture PPT - Carol Lee Lab - University of Wisconsin
Lecture PPT - Carol Lee Lab - University of Wisconsin

... • Metabolic-rate hypothesis. Mutation rate that is due to endogenous or exogenous mutagens, such as oxygen radicals. This hypothesis argues that groups with higher metabolic rates produce more free radicals, which leads to greater DNA damage and faster mutation and evolutionary rates. • DNA repair h ...
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... •The language of RNA is in the form of codons – which are groups of three nucleotides, such as AUG, GCC or AAA. •This is called the triplet code. •The sequence of codons on the mRNA determines the sequence of amino acids. •Each codon codes for a specific amino acid. •There are only 20 amino acids th ...
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Structure of Nucleic Acids
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... DNA consists of two long polymers of simple units called nucleotides, with backbones made of sugarsand phosphate groups joined by ester bonds. These two strands run in opposite directions to each other and are therefore anti-parallel. Attached to each sugar is one of four types of molecules called b ...
Product Datasheets
Product Datasheets

... This System eliminates restriction enzyme digestion, dephosphorylation, blunting sticky ends, nick ligation, terminal adenylation and intermediate vectors from PCR product cloning. This System takes only 20-30 minutes to fuse DNA fragments to one DNA molecule. This System is recommended for the foll ...
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... Benefits of genetically modified plants – Transgenic crops decrease applications of pesticides, saving fuel, labor, and money – GM plants can be sold at a lower price due to ...
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DNA: The Molecule of Heredity
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... What is the function of DNA polymerase III? • It adds nucleotide pairs to the growing DNA strand • It adds single nucleotides to the growing DNA strand • It unwinds the DNA • It attaches the RNA primers to the DNA strand ...
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Foundations of Biology - Geoscience Research Institute
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... Generally mtDNA and ctDNA is circular and contains genes for multimeric proteins, some portion of which are also coded for in the nucleus Extranuclear DNA has a rate of mutation that is independent of nuclear DNA Generally, but not always, all the RNAs needed for transcription and translation are fo ...
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...  In population genetics, Sewall Wright's coefficient of relationship or coefficient of relatedness or relatedness or r is a measure for the level of consanguinity between two given individuals.  The coefficient of inbreeding is calculated for a single individual, and is a measure for the amount of ...
DNA_Replication 2015
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... • Genetic information flow can be divided into three stages – Replication: DNA is duplicated (Figure 4.3) – Transcription: information from DNA is transferred to RNA ...
Ovulation through implantation
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... • The male sperm is the smallest cell in the human body and the female ovum is the largest cell; 90,000 times heavier that the male sperm. • Everyday a healthy young male produces 100 million sperm (1000 sperms a second). Each sperm contains a unique selection of the father’s genetic material. • The ...
Class 34 Genes and Behavior, continued Obesity Comparative
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... •  Measure which neurons in the brain are active during or just after food intake; use this information to develop drug targets ...
RNA 8.1 Identifying DNA as the Genetic Material
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... 8.1 Identifying DNA as the Genetic Material The transcription process is similar to replication. • Transcription and replication both involve complementary (matching up) base pairing. • The two processes have different end results. – Replication copies all the DNA; transcription copies one gene gro ...
recombinant dna technology and genetic engineering
recombinant dna technology and genetic engineering

... The host plasmid pK19 only has a single EcoR1 site. Inserting the R. sphaeroides DNA disrupts the base pair sequence in the region of the plasmid chromosome that codes for the alpha peptide5, 6. Cloning a Gene (Polymerase Chain Reaction): Clone: Making exact genetic copies of whole organisms, cells ...
Pierce5e_ch19_lecturePPT
Pierce5e_ch19_lecturePPT

... • Knock-in mice: a mouse carries an inserted DNA sequence at specific locations ...
The Human Genome.
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... of the human genome  If we include introns and regulatory sequences associated with genes, the total amount of DNA that is gene-related - coding and non-coding - constitutes about 25 % of ...
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Mitochondrial DNA



Mitochondrial DNA (mtDNA or mDNA) is the DNA located in mitochondria, cellular organelles within eukaryotic cells that convert chemical energy from food into a form that cells can use, adenosine triphosphate (ATP). Mitochondrial DNA is only a small portion of the DNA in a eukaryotic cell; most of the DNA can be found in the cell nucleus and, in plants, in the chloroplast.In humans, mitochondrial DNA can be assessed as the smallest chromosome coding for 37 genes and containing approximately 16,600 base pairs. Human mitochondrial DNA was the first significant part of the human genome to be sequenced. In most species, including humans, mtDNA is inherited solely from the mother.The DNA sequence of mtDNA has been determined from a large number of organisms and individuals (including some organisms that are extinct), and the comparison of those DNA sequences represents a mainstay of phylogenetics, in that it allows biologists to elucidate the evolutionary relationships among species. It also permits an examination of the relatedness of populations, and so has become important in anthropology and field biology.
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