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Novel approaches to explore mechanisms of
Novel approaches to explore mechanisms of

... Epilepsy comprises a family of neurological disorders characterized by recurrent seizures, which can be highly debilitating. Up to 30% of patients with temporal lobe epilepsy, the most common form of the disorder in adults, arising in the hippocampus, cannot be effectively treated by current pharmac ...
Memory consolidation, retrograde amnesia, and the temporal lobe
Memory consolidation, retrograde amnesia, and the temporal lobe

... case HM, whose resected areas were recently confirmed by MRI (Corkin et al., 1997). Conventionally, memory contents have been fractionated into subtypes, such as episodic, semantic, and non-declarative memory, and more recently, finer distinctions, such as autobiographical episodes, and autobiograph ...
Differential functional connectivity of rostral
Differential functional connectivity of rostral

Long-term consolidation of declarative memory
Long-term consolidation of declarative memory

Laboratory Guide - Sites@Duke
Laboratory Guide - Sites@Duke

... and the diencephalon, which becomes the thalamus and hypothalamus (see Figure 1B). These structures together make up the adult forebrain (= derivatives of the prosencephalon). The spaces inside the hemispheres are known as the lateral ventricles, and the space inside the diencephalon is the third ve ...
Frankland lecture FINAL
Frankland lecture FINAL

... neurons (‘neurons that fire together, wire together’) -- synaptic strengthening provides basis for formation of cell assemblies (i.e., collections of neurons that fire together at time of learning and during retrieval) ...
Short-Term and Long-Term Memory in Early
Short-Term and Long-Term Memory in Early

... shown a list of spatial locations and then given two-choice recognition trials 3-72 s later. Patients with amygdalahippocampal excisions performed significantly worse than controls on this task. However, the data were not analyzed ...
Aberrant changes of somatostatin and neuropeptide Y in brain of a
Aberrant changes of somatostatin and neuropeptide Y in brain of a

... hippocampal CA1, CA3 and hilus, the entorhinal cortex of temporal lobe cortex and cerebellum. The fields to be counted were located by the characteristic landmarks in the histological map, such as the folding of the pyramidal cell layer in areas of CA1 and CA3. The immuno-positive cells within 100 c ...
FREE Sample Here - Find the cheapest test bank for your
FREE Sample Here - Find the cheapest test bank for your

... The hippocampus is involved in the formation and storage of memories. People who have hippocampus damage cannot retain new memories after the damage. Thalamus An important function of the thalamus is to sort through information and send it to the appropriate place in the forebrain for further integr ...
Dopamine: a potential substrate for synaptic plasticity and memory
Dopamine: a potential substrate for synaptic plasticity and memory

... of the lacunosum moleculare of CA1 and stratum moleculare of the subiculum whereas no binding to D2 receptors exists in the temporal hippocampus (Goldsmith and Joyce, 1994). D3 receptor has also been detected at a low level in the hippocampus, while a high level of D4 receptor was later shown to ref ...
Telencephalon
Telencephalon

... Some basal ganglia neurons mainly receive input from cortex; others – mainly output to thalamus ...
A Biologically Plausible Spiking Neuron Model of Fear Conditioning
A Biologically Plausible Spiking Neuron Model of Fear Conditioning

... to perform computations on the vectors being represented. The synaptic connection weights between populations can be solved for analytically in order to efficiently compute an aproximation to any function. In addition, these synaptic connection weights can be learned during a simulation to approxim ...
A Neuropsychological Model of Memory and Consciousness
A Neuropsychological Model of Memory and Consciousness

... Umilta, 1990,1991, for a discussion of working memory and consciousness), it is picked up automatically by the hippocampal component, which is a functional unit that comprises the hippocampus and related limbic structures in the medial temporal lobe and diencephalon.' Thus, only consciously experien ...
Prefrontal Cortex, Emotion, and Approach/Withdrawal Motivation
Prefrontal Cortex, Emotion, and Approach/Withdrawal Motivation

... regarding the role of prefrontal cortex, along with some other critical brain regions, in emotion and motivation. Seemingly contradictory findings have often appeared in this literature. Research attempting to resolve these contradictions has been the basis of new areas of growth and has led to more ...
LINKS BETWEEN LTP AND LEARNING AND MEMORY
LINKS BETWEEN LTP AND LEARNING AND MEMORY

... Water maze task is complex and requires animals to learn the general task requirement as well as the specific location of the hidden platform Non-spatial pretraining can separate the two kinds of learning Rats first made familiar with the general task requirements and subsequently trained after rece ...
Human Neural Systems for Face Recognition and Social
Human Neural Systems for Face Recognition and Social

... Warrington 1993), a selective impairment of the ability to recognize familiar faces with relatively intact ability to recognize other objects, suggested a dissociation between neural systems that mediate face and object recognition. The lesions that cause prosopagnosia are found in ventral occipitot ...
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The Interacting Neuroendocrine Network in Stress
The Interacting Neuroendocrine Network in Stress

... nervous system (ANS) functional hyperactivities [11]. For instance, it has been observed that neonatal handling of rats induces a lower HPA reactivity and a slower rate of aging of cognitive functions associated with a reduced loss of hippocampal function [12,13]. In addition, different studies have ...
2. Organization of the Exam and Assessment Criteria
2. Organization of the Exam and Assessment Criteria

... The problem of correlation between psychical and physiological, the mind and brain problem: history and approaches. Systemic and integrative psychophysiology. Fields of research in systemic psychophysiology. Sustaining organism homeostasis. Correlation between behavioral activity and reactivity, res ...
2. Organization of the Exam and Assessment Criteria
2. Organization of the Exam and Assessment Criteria

... The problem of correlation between psychical and physiological, the mind and brain problem: history and approaches. Systemic and integrative psychophysiology. Fields of research in systemic psychophysiology. Sustaining organism homeostasis. Correlation between behavioral activity and reactivity, res ...
The Biological Perspective
The Biological Perspective

... A neuron that’s at rest—not currently firing a neural impulse or message—is actually electrically charged. The inside of the cell is really a semi-liquid solution in which there are charged particles, or ions. There is a semi-liquid solution surrounding the outside of the cell as well, which also co ...
Effects of lithium and valproate on amphetamine
Effects of lithium and valproate on amphetamine

A Neural Circuit Basis for Spatial Working Memory
A Neural Circuit Basis for Spatial Working Memory

... scale of seconds is a critical component of cognitive functions such as language, abstract thought, planning and most of the mental processes we associate with human intelligence. Working memory, as this critical function is known, can be thought of as a blackboard of the mind (Baddeley 1992). Becau ...
Document
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... REM sleep may be a reverse learning process where superfluous information is purged from the brain ...
What is a Brain State
What is a Brain State

... intuitive account of what we expect brain states to be as well as a convincing argument against a common candidate for knowledge about brain states which is currently ‘on the scene.’ I then introduce a distinction between brain states and states of the brain (cf. Chalmers’ specific and background NC ...
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Limbic system



The limbic system (or paleomammalian brain) is a complex set of brain structures located on both sides of the thalamus, right under the cerebrum. It is not a separate system but a collection of structures from the telencephalon, diencephalon, and mesencephalon. It includes the olfactory bulbs, hippocampus, amygdala, anterior thalamic nuclei, fornix, columns of fornix, mammillary body, septum pellucidum, habenular commissure, cingulate gyrus, parahippocampal gyrus, limbic cortex, and limbic midbrain areas.The limbic system supports a variety of functions including epinephrine flow, emotion, behavior, motivation, long-term memory, and olfaction. Emotional life is largely housed in the limbic system, and it has a great deal to do with the formation of memories.Although the term only originated in the 1940s, some neuroscientists, including Joseph LeDoux, have suggested that the concept of a functionally unified limbic system should be abandoned as obsolete because it is grounded mainly in historical concepts of brain anatomy that are no longer accepted as accurate.
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