Increased Functional Half-life of Fibroblast Growth Factor
... formation) while simultaneously increasing the thermodynamic stability of the protein. This is especially true considering that protein unfolding, which is dependent on protein stability, is often a necessary first step for the irreversible denaturation pathway resulting from exposure of the reactiv ...
... formation) while simultaneously increasing the thermodynamic stability of the protein. This is especially true considering that protein unfolding, which is dependent on protein stability, is often a necessary first step for the irreversible denaturation pathway resulting from exposure of the reactiv ...
Dehydrogenase in Saccharomyces cerevisiae
... -571), which would be read in the opposite sense, is capable of encoding a polypeptide of 77 residues; the other (sequence not complete, terminating at - 858) could encode a polypeptide of at least 76 amino acids. A search of the NBRF protein data base showed no strong homology between the two predi ...
... -571), which would be read in the opposite sense, is capable of encoding a polypeptide of 77 residues; the other (sequence not complete, terminating at - 858) could encode a polypeptide of at least 76 amino acids. A search of the NBRF protein data base showed no strong homology between the two predi ...
UDP-GLYCOSYLTRANSFERASES OF PLANT HORMONES
... cosylation or O-phosphorylation, since the first order structure of ZmIAGLU was found to contain three sites for a potential N-glycosylation (N-X(S,T); N-S, N-T) and the S/T-XR/K motif specific for substrates of protein kinase C [21]. The suggestion of control over activity of IAGlc synthase by phos ...
... cosylation or O-phosphorylation, since the first order structure of ZmIAGLU was found to contain three sites for a potential N-glycosylation (N-X(S,T); N-S, N-T) and the S/T-XR/K motif specific for substrates of protein kinase C [21]. The suggestion of control over activity of IAGlc synthase by phos ...
Jane M. Carlton, , 207 (2007); DOI: 10.1126/science.1132894
... 29 core meiotic genes found, several are general repair proteins required for meiotic progression in other organisms (21), and eight are meiosisspecific proteins. Thus, T. vaginalis contains either recent evolutionary relics of meiotic machinery or genes functional in meiotic recombination in an as- ...
... 29 core meiotic genes found, several are general repair proteins required for meiotic progression in other organisms (21), and eight are meiosisspecific proteins. Thus, T. vaginalis contains either recent evolutionary relics of meiotic machinery or genes functional in meiotic recombination in an as- ...
Proteomic Analysis of Neisseria gonorrhoeae Biofilms
... sodium azide. After 48 h, the biofilm cells were harvested from the chambers grown in L-Arg supplemented MDM. Based upon the relative yields of planktonic and biofilm cells from the biofilm growth apparatus, it was most economical to prepare unlabeled (L) biofilm cells and 13C6-Arg-labeled (H) plank ...
... sodium azide. After 48 h, the biofilm cells were harvested from the chambers grown in L-Arg supplemented MDM. Based upon the relative yields of planktonic and biofilm cells from the biofilm growth apparatus, it was most economical to prepare unlabeled (L) biofilm cells and 13C6-Arg-labeled (H) plank ...
Biochemical and Molecular Characterization of the Chicken
... (McGuire et al., 1992) that is postulated to function in nervous system development (Greenberg et al., 1990). Thus, although a number of LIM domain proteins lack any wellcharacterized DNA-binding domain, many of these proteins have also been implicated in processes such as cell differentiation and e ...
... (McGuire et al., 1992) that is postulated to function in nervous system development (Greenberg et al., 1990). Thus, although a number of LIM domain proteins lack any wellcharacterized DNA-binding domain, many of these proteins have also been implicated in processes such as cell differentiation and e ...
Codrea_Biochem_07 - The University of Texas at Austin
... changed to signify the type of bonding of the atom. This bonding is typically designated as the number 3 for sp3, 2 for sp2, or 0 for hydrogens. A binary representation of the ligand is created and the atoms in the ligand that act as hydrogen bond acceptors or donors must be listed. A hydrogen bond ...
... changed to signify the type of bonding of the atom. This bonding is typically designated as the number 3 for sp3, 2 for sp2, or 0 for hydrogens. A binary representation of the ligand is created and the atoms in the ligand that act as hydrogen bond acceptors or donors must be listed. A hydrogen bond ...
Towards a molecular understanding of adaptive thermogenesis
... control adaptive thermogenesis. The presence of the adipocytederived hormone leptin and neuropeptides, both of which regulate energy balance in the hypothalamus, is further evidence for regulation of thermogenesis by the brain and is discussed in detail in the review by Schwartz et al., pp. 661–671. ...
... control adaptive thermogenesis. The presence of the adipocytederived hormone leptin and neuropeptides, both of which regulate energy balance in the hypothalamus, is further evidence for regulation of thermogenesis by the brain and is discussed in detail in the review by Schwartz et al., pp. 661–671. ...
BIOINFORMATICS ORIGINAL PAPER Going from where to why—interpretable prediction of protein subcellular localization
... localization. However, in many cases only one or two of feature types were included in one predictor. In our study, we included numerous types of features and properties. First, we make use of sequence-derived features. These include amino acid composition, normalized amino acid composition and pseu ...
... localization. However, in many cases only one or two of feature types were included in one predictor. In our study, we included numerous types of features and properties. First, we make use of sequence-derived features. These include amino acid composition, normalized amino acid composition and pseu ...
determination of molecular weight
... Analysis as a single ideal species of the sedimentation equilibrium concentration gradient in the cell yields buoyant molecular weights. In order to convert these values to absolute molecular weights, it is necessary to determine the partial specific volume for the glycoprotein. Experimentally this ...
... Analysis as a single ideal species of the sedimentation equilibrium concentration gradient in the cell yields buoyant molecular weights. In order to convert these values to absolute molecular weights, it is necessary to determine the partial specific volume for the glycoprotein. Experimentally this ...
Regulation of pyruvate, orthophosphate dikinase by ADP
... component in addition to an electrostatic one since substitution of Thr by Tyr or Phe (but not Val), two neutral amino acids with bulky side chains, also dramatically inhibits dikinase activity (Table 2). However, high-resolution crystal structures of these wild-type and mutant C4 enzymes are needed ...
... component in addition to an electrostatic one since substitution of Thr by Tyr or Phe (but not Val), two neutral amino acids with bulky side chains, also dramatically inhibits dikinase activity (Table 2). However, high-resolution crystal structures of these wild-type and mutant C4 enzymes are needed ...
Bioinformatic approach to identify penultimate amino acids efficient
... NME is carried out by methionine aminopeptidase (MAP). Eubacteria contain only one type of MAP whereas eukaryotes contain two (MAP1 and MAP2). The efficiency of NME depends heavily on the penultimate (the second) amino acid. In the yeast, Saccharomyces cerevisiae, NME occurs most efficiently when th ...
... NME is carried out by methionine aminopeptidase (MAP). Eubacteria contain only one type of MAP whereas eukaryotes contain two (MAP1 and MAP2). The efficiency of NME depends heavily on the penultimate (the second) amino acid. In the yeast, Saccharomyces cerevisiae, NME occurs most efficiently when th ...
Supplemental Material
... pSwtRlacZwhiteRz. The choice of these five amino acid residues is based on the published structure of E. coli -gal (JUERS et al. 2001), in which these five amino acid residues seem to contribute to the formation of dimer and tetramer of -gal, which is essential for its activity. We predicted tha ...
... pSwtRlacZwhiteRz. The choice of these five amino acid residues is based on the published structure of E. coli -gal (JUERS et al. 2001), in which these five amino acid residues seem to contribute to the formation of dimer and tetramer of -gal, which is essential for its activity. We predicted tha ...
Chapter 9 Proteins - Angelo State University
... • Vasopressin and oxytocin are nonapeptide hormones secreted by the pituitary gland. Six of the amino acid residues are held in a loop by disulfide bridges formed by the oxidation of two cysteine residues. Even though the molecules are very similar, their biological functions are quite different: – ...
... • Vasopressin and oxytocin are nonapeptide hormones secreted by the pituitary gland. Six of the amino acid residues are held in a loop by disulfide bridges formed by the oxidation of two cysteine residues. Even though the molecules are very similar, their biological functions are quite different: – ...
Similarities between putative transport proteins of plant viruses
... with those of two peptides encoded by mitochondrial introns of Saccharomyces cerevisiae. Possibly significant similarities were found between the CaMV protein and several cellular proteins (Hull et al., 1986; MartinezIzquierdo et al., 1987). Amino acid sequences derived from nucleotide sequences are ...
... with those of two peptides encoded by mitochondrial introns of Saccharomyces cerevisiae. Possibly significant similarities were found between the CaMV protein and several cellular proteins (Hull et al., 1986; MartinezIzquierdo et al., 1987). Amino acid sequences derived from nucleotide sequences are ...
Quantitative iTRAQ Proteomics Revealed Possible Roles for
... whole system approach, this proteomics technique provides a complementary strategy to unravel the mechanisms underlying plant Al tolerance (Jedmowski et al., 2014; Zheng et al., 2014). Several proteomics studies on Al stressed roots have been conducted in different plant species such as rice (Yang e ...
... whole system approach, this proteomics technique provides a complementary strategy to unravel the mechanisms underlying plant Al tolerance (Jedmowski et al., 2014; Zheng et al., 2014). Several proteomics studies on Al stressed roots have been conducted in different plant species such as rice (Yang e ...
Abundant Expression of ras Proteins in Aplysia Neurons
... three known mammalian ras proto-oncogenes as well as with the products of ras genes in S. cerevisiae, Dictyostelium, and Drosophila (36, 37, 38). The most abundant fluorescence was observed in neurons; little or no fluorescence was detected in the connective tissue sheath that surrounds the neuronal ...
... three known mammalian ras proto-oncogenes as well as with the products of ras genes in S. cerevisiae, Dictyostelium, and Drosophila (36, 37, 38). The most abundant fluorescence was observed in neurons; little or no fluorescence was detected in the connective tissue sheath that surrounds the neuronal ...
Bioinformatics Tools Review ()
... The goals of this exercise are to introduce sequence analysis tools for predicting where a protein is likely to reside in the cell predicting protein domains that likely span a cellular membrane predicting amino acid sequences likely to be highly antigenic In addition, the exercise will allow studen ...
... The goals of this exercise are to introduce sequence analysis tools for predicting where a protein is likely to reside in the cell predicting protein domains that likely span a cellular membrane predicting amino acid sequences likely to be highly antigenic In addition, the exercise will allow studen ...
SCit: web tools for protein side chain
... conformation corresponding to the most probable conformation of the side chain in a backbone-independent rotamer library. (iv) It performs a series of preliminary calculations, such as the compilation of the rotamer library compatible with the structure, the positioning of hydrogens and the calculat ...
... conformation corresponding to the most probable conformation of the side chain in a backbone-independent rotamer library. (iv) It performs a series of preliminary calculations, such as the compilation of the rotamer library compatible with the structure, the positioning of hydrogens and the calculat ...
Poster
... Bacteria are the cause of many diseases. Normally our bodies fight these infections, but sometimes assistance is necessary through prescription antibiotics. Antibiotics kill or inhibit the growth of bacteria by interfering with enzymes or processes specific to bacterial function. For instance, many ...
... Bacteria are the cause of many diseases. Normally our bodies fight these infections, but sometimes assistance is necessary through prescription antibiotics. Antibiotics kill or inhibit the growth of bacteria by interfering with enzymes or processes specific to bacterial function. For instance, many ...
Structure of the Coat Protein-binding Domain of
... structures are often thought to simply bind to one another spontaneously (by ``self assembly'') once they are properly folded, but in some cases still other proteins are required to catalyze such assembly reactions. The viral scaffolding proteins are the best understood catalysts of protein polymeri ...
... structures are often thought to simply bind to one another spontaneously (by ``self assembly'') once they are properly folded, but in some cases still other proteins are required to catalyze such assembly reactions. The viral scaffolding proteins are the best understood catalysts of protein polymeri ...
A novel sensitive method for the detection of user
... it has been shown for a number of proteins that biased segments that contain amino acids with similar chemical properties are involved in a variety of molecular functions and human diseases. A detailed large-scale analysis of the functional implications and evolutionary conservation of different com ...
... it has been shown for a number of proteins that biased segments that contain amino acids with similar chemical properties are involved in a variety of molecular functions and human diseases. A detailed large-scale analysis of the functional implications and evolutionary conservation of different com ...
Metabolic and physiological interdependencies in the
... Figure 2 Density gradient enrichment of symbiont cells and host components followed by CARD-FISH. (a) Step-wise workflow of the density gradient enrichment method for physical separation of B. azoricus host and symbiont cells. Sampling for tissue-based metaproteomic analysis of whole gill and foot t ...
... Figure 2 Density gradient enrichment of symbiont cells and host components followed by CARD-FISH. (a) Step-wise workflow of the density gradient enrichment method for physical separation of B. azoricus host and symbiont cells. Sampling for tissue-based metaproteomic analysis of whole gill and foot t ...