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Sarepta Therapeutics Announces Presentation at the 52nd
Sarepta Therapeutics Announces Presentation at the 52nd

... Marburg hemorrhagic fever is a severe and potentially fatal disease in humans first recognized in 1967. It is caused by an RNA virus of the Filoviridae family and is understood to be endemic to Africa. The Marburg virus is classified as a Category A bioterrorism agent by the Centers for Disease Cont ...
Community Crisis Management Lessons from
Community Crisis Management Lessons from

... allowed into port the ships carrying infected refugees from the West Indies' rebellion with France. From this oversight it is apparent that yellow fever suspicion was not a concern. Philadelphia had not experienced an outbreak in thirty years, leaving yellow fever forgotten by most. Lack of exposure ...
Overview of Category A Bioterrorism Agents
Overview of Category A Bioterrorism Agents

... administer antibiotics if needed • Vaccination – not recommended as PEP – Short incubation period – Incomplete protection for inhalational tularemia ...
VIRAL DISEASES
VIRAL DISEASES

... East, Africa, Asia, and Central and South America where the serologic prevalence of exposure to HAV has been reported to be as high as 96 percent (Oldfield et al., 1991; Heintges and Wand, 1997; el-Hazmi, 1989a). Hepatitis B virus transmission occurs via parenteral routes with transmission through c ...
Urbanization and the Epidemiology of Infectious Diseases
Urbanization and the Epidemiology of Infectious Diseases

... A = sylvatic yellow fever ever reported in last 20 years; B = sylvatic transmission deemed possible because of entomological and ecological characteristics; C = sylvatic transmission deemed impossible; *First (possibly atypical) symptoms: fever, malaise, headache, nausea, myalgia; †During 10 days be ...
Jan Dulay - web.biosci.utexas.edu
Jan Dulay - web.biosci.utexas.edu

... with a fever of unknown origin, 18 (47.4%) did not know the proper symptoms of murine typhus:  Responded don’t know, fever with rash only, or no fever ...
Appendix A: Calculations of transition rates in the outcome tree
Appendix A: Calculations of transition rates in the outcome tree

... The Q fever acute illness is similar to the acute illness of influenza A(H1N1) pdm09, which is used as a proxy for Q fever acute illness, but is different in two aspects. First, those under 15 years of age are far less frequently symptomatic (12.5%) than cases that are over 15 years of age (40%) [1] ...
"Technical, Economics and Legal Obstacles to the Development of Faccines and other Therapeutics for Potential Bioterrorism Agents" 
"Technical, Economics and Legal Obstacles to the Development of Faccines and other Therapeutics for Potential Bioterrorism Agents" 

... it both promotes and discourages the development of new vaccines. – While states continue to take principal responsibility for immunization infrastructure and delivery, it can no longer be assumed that they will share responsibility for vaccine purchase with the federal government. ...
Infectious Diseases
Infectious Diseases

... Identification: Signs and symptoms of Hepatitis A, B, C virus infection are impossible to tell them apart from each other. Acute disease tends to be mild and the onset is gradual with mild nonspecific symptoms (loss of appetite, nausea, or a general feeling of being ill), and most infections have no ...
scarlet fever - UMF IASI 2015
scarlet fever - UMF IASI 2015

... Infection during early pregnancy may result in serious abnormalities of the fetus, referred to as the congenital rubella syndrome. ...
#1 - School of Public Health
#1 - School of Public Health

... administer antibiotics if needed • Vaccination – not recommended as PEP – Short incubation period – Incomplete protection for inhalational tularemia ...
P. malariae
P. malariae

... A vector-borne infectious disease caused by protozoan parasites. It is widespread in tropical and subtropical regions ...
Zika Virus in the Americas — Yet Another Arbovirus Threat
Zika Virus in the Americas — Yet Another Arbovirus Threat

... have not yet been developed. Moreover, because Zika is closely related to dengue, serologic samples may cross-react in tests for either virus. Gene-detection tests such as the polymerase-chain-reaction assay can reliably distinguish the three viruses, but Zika-specific tests are not yet widely avail ...
imovax polio
imovax polio

... To be injected by subcutaneous or intramuscular route. It is recommended to inject this vaccine as soon as 2 months old. Primary immunization: 2 injections of 0,5 ml should be administered at interval of one month and boosters one year after second injection. Destroy the syringe after use. Side Effe ...
Lassa fever and Marburg virus disease
Lassa fever and Marburg virus disease

... detectable (often at a low titre) in the third week after the onset of the disease. For serological diagnosis 2-5 ml of serum is obtained during the first 2 weeks of illness and again 4-8 weeks after the onset. The sera should be handled with care since they may contain live virus. When sera are sep ...
Is My Child Ill - Prior Lake Savage Area Schools
Is My Child Ill - Prior Lake Savage Area Schools

... Symptoms: Begins with a runny nose, low-grade fever and mild cough. In 7-14 days, a persistent cough develops that can occur in explosive bursts (paroxysmal or whooping cough), sometimes followed by vomiting. Coughing occurs more frequently at night. Symptoms are less severe in older children and ad ...
Immunizations_Communicable Diseae_10
Immunizations_Communicable Diseae_10

... 1st 12 months or older 2nd dose kindergarten visit If no record of second dose it should be given at 11 to 12 ...
Page - Legionnaires` disease outbreak investigation
Page - Legionnaires` disease outbreak investigation

... occur throughout the year, with most cases occuring in late summer early and autumn [3; 4; 5]. Clusters (cases associated in space and time) and outbreaks (cases associated in space and time with a common source) can also occur [6; 7; 8; 9]. A large proportion of cases are travel-associated, acquire ...
Urinary Tract Infection
Urinary Tract Infection

... symptoms. If your child is sick and has a fever, the best method is to treat with intra-venous (IV) antibiotics. Occasionally, when children are so ill that they cannot keep food down, they may require admission to the hospital for IV fluids and antibiotics. In other cases, treatment is usually as a ...
DROUGHT-ASSOCIATED CHIKUNGUNYA EMERGENCE ALONG
DROUGHT-ASSOCIATED CHIKUNGUNYA EMERGENCE ALONG

... (expected because of drought) has been shown to increase domestic Aedes aegypti populations in coastal Kenya.16 Climatic effects, particularly elevated temperature, on virus development in vector mosquitoes also could have enhanced transmission efficiency.17 Interestingly, epidemic dengue-3 emergenc ...
Crimean-Congo hemorrhagic fever: a
Crimean-Congo hemorrhagic fever: a

... through the later mode [4, 24, 29]. Pre-hemorrhagic symptoms are non specific and include fever, chills, severe headache, dizziness, photophobia, myalgia and arthralagia. This phase may last for 1-7 days [44]. The hemorrhagic phase develops suddenly lasting for 2-3 days [44]. A petechial rash may be ...
MUMPS
MUMPS

... size over next 2 to 3 days accompanied severe pain and normal or high temperature. One parotid enlarges after the other. The orifice of Stensen’s duct is edematous and erythematous. Parotid returns to normal size within a week. Patients with parotitis have difficulty with pronunciation and masticat ...
Viral haemorrhagic fevers in South Africa
Viral haemorrhagic fevers in South Africa

... spread. There have been a total of 466 laboratory-confirmed cases with 373 deaths (an average fatality rate of 80%, range 23 - 100%). [45] The largest outbreak centered in Uige Province in Angola, with 252 laboratory-confirmed cases from 2004 to 2005 with a 90% case fatality rate.[46] In six of the ...
Detection of yellow fever virus: a comparison of
Detection of yellow fever virus: a comparison of

... Yellow fever virus quantitation is performed routinely by cultivation of virus containing samples using susceptible cells. Counting of the resulting plaques provides a marker for the number of infectious particles present in the sample. This assay usually takes up to 5 days before results are obtain ...
NEW JERSEY DEPARTMENT OF HEALTH COMMUNICABLE
NEW JERSEY DEPARTMENT OF HEALTH COMMUNICABLE

...  There are a variety of ways to determine what is causing an outbreak. Occasionally, when  an outbreak is reported, laboratory testing has already been conducted and a diagnosis  has been made. For most outbreaks, however, this is not the case. Also, some diseases  must be diagnosed clinically – th ...
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Yellow fever



Yellow fever, known historically as yellow jack, yellow plague, or bronze john, is an acute viral disease. In most cases, symptoms include fever, chills, loss of appetite, nausea, muscle pains particularly in the back, and headaches. Symptoms typically improve within five days. In some people within a day of improving, the fever comes back, abdominal pain occurs, and liver damage begins causing yellow skin. If this occurs, the risk of bleeding and kidney problems is also increased.The disease is caused by the yellow fever virus and is spread by the bite of the female mosquito. It infects only humans, other primates, and several species of mosquitoes. In cities, it is spread primarily by mosquitoes of the Aedes aegypti species. The virus is an RNA virus of the genus Flavivirus. The disease may be difficult to tell apart from other illnesses, especially in the early stages. To confirm a suspected case, blood sample testing with polymerase chain reaction is required.A safe and effective vaccine against yellow fever exists and some countries require vaccinations for travelers. Other efforts to prevent infection include reducing the population of the transmitting mosquito. In areas where yellow fever is common and vaccination is uncommon, early diagnosis of cases and immunization of large parts of the population is important to prevent outbreaks. Once infected, management is symptomatic with no specific measures effective against the virus. In those with severe disease, death occurs in about half of people without treatment.Yellow fever causes 200,000 infections and 30,000 deaths every year, with nearly 90% of these occurring in Africa. Nearly a billion people live in an area of the world where the disease is common. It is common in tropical areas of South America and Africa, but not in Asia. Since the 1980s, the number of cases of yellow fever has been increasing. This is believed to be due to fewer people being immune, more people living in cities, people moving frequently, and changing climate. The disease originated in Africa, where it spread to South America through the slave trade in the 17th century. Since the 17th century, several major outbreaks of the disease have occurred in the Americas, Africa, and Europe. In the 18th and 19th centuries, yellow fever was seen as one of the most dangerous infectious diseases. In 1927 yellow fever virus became the first human virus to be isolated.
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