ANTI-INFLAMMATORY EFFECT OF THE SERRATIOPEPTIDASE
... There are many doubts raised about the efficacy of serratiopeptidases (11). It is marketed as orally effective antiinflammatory drug despite of its protein nature. There are many enteric coated formulations available which claim that they are not destroyed by gastric acid and get absorbed by intesti ...
... There are many doubts raised about the efficacy of serratiopeptidases (11). It is marketed as orally effective antiinflammatory drug despite of its protein nature. There are many enteric coated formulations available which claim that they are not destroyed by gastric acid and get absorbed by intesti ...
DrugLecture2001
... • Some highly addicting drugs (e.g., cocaine) have minimal withdrawal symptoms ...
... • Some highly addicting drugs (e.g., cocaine) have minimal withdrawal symptoms ...
WHAT`S THE NEXT STEP?
... Cushing's Syndrome results from chronic exposure to elevated levels of circulating free glucocorticoids. Cushing's Syndrome may be endogenous; however, the most common cause of Cushing's Syndrome is use of supraphysiological amounts of exogenous glucocorticoids (Newell-Price et al., 2006). This is t ...
... Cushing's Syndrome results from chronic exposure to elevated levels of circulating free glucocorticoids. Cushing's Syndrome may be endogenous; however, the most common cause of Cushing's Syndrome is use of supraphysiological amounts of exogenous glucocorticoids (Newell-Price et al., 2006). This is t ...
Doctoral theses MÁRIA TÓTH MD. Semmelweis University
... drugs are added to the others. The exact identifications of mechanism of interactions need to clarify the pharmacokinetic and clinical pharmacology properties of the drugs are involved into the interaction. The knowing of the potential interaction of tacrolimus as narrow therapic range immunosuppres ...
... drugs are added to the others. The exact identifications of mechanism of interactions need to clarify the pharmacokinetic and clinical pharmacology properties of the drugs are involved into the interaction. The knowing of the potential interaction of tacrolimus as narrow therapic range immunosuppres ...
抗 癫 痫 药
... degradation of cAMP→cAMP↑…… →physiological effect Central neuromodulator antagonist → effect of adenosine →block the inhibiting effect of adenosine on central nervous system→stimulate the central nervous system. Increasing intracellular free calcium Competitive antagonists of Benzodiazepine receptor ...
... degradation of cAMP→cAMP↑…… →physiological effect Central neuromodulator antagonist → effect of adenosine →block the inhibiting effect of adenosine on central nervous system→stimulate the central nervous system. Increasing intracellular free calcium Competitive antagonists of Benzodiazepine receptor ...
Enhancement of Dissolution rate of Rifabutin by preparation of
... solubility problems associated with poorly soluble drugs.2,3 Poor water solubility of the new chemical entity is caused by hydrophobicity, i.e., inability to form hydrogen bonds with water and/ or by high lattice energy. One market analysis report estimated that worldwide sales of about $37 billion ...
... solubility problems associated with poorly soluble drugs.2,3 Poor water solubility of the new chemical entity is caused by hydrophobicity, i.e., inability to form hydrogen bonds with water and/ or by high lattice energy. One market analysis report estimated that worldwide sales of about $37 billion ...
NSAID
... special smells, tastes, or sounds. Most migraines are accompanied by nausea and vomiting. Triggers for migraines include nitrates, monosodium glutamate (MSG)—found in many Asian foods, red wine, perfumes, food additives, caffeine, chocolate, and aspartame. By avoiding foods containing these substanc ...
... special smells, tastes, or sounds. Most migraines are accompanied by nausea and vomiting. Triggers for migraines include nitrates, monosodium glutamate (MSG)—found in many Asian foods, red wine, perfumes, food additives, caffeine, chocolate, and aspartame. By avoiding foods containing these substanc ...
drl_DAIDS_NVP_final_ risk_list_7_2010
... general feeling of discomfort, and/or liver damage described above, kidney problems, and/or changes in white blood cell levels. Muscle break down causing muscle aches or pain has been observed in some people experiencing skin and/or liver reactions associated with nevirapine. Rash is the most common ...
... general feeling of discomfort, and/or liver damage described above, kidney problems, and/or changes in white blood cell levels. Muscle break down causing muscle aches or pain has been observed in some people experiencing skin and/or liver reactions associated with nevirapine. Rash is the most common ...
Antiarrhythmic Drugs
... • Ventricular arrhythmias are common in most people and are usually not a problem but… • VA’s are most common cause of sudden death • Majority of sudden death occurs in people with neither a previously known heart disease nor history of VA’s • Medications which decrease incidence of VA’s do not decr ...
... • Ventricular arrhythmias are common in most people and are usually not a problem but… • VA’s are most common cause of sudden death • Majority of sudden death occurs in people with neither a previously known heart disease nor history of VA’s • Medications which decrease incidence of VA’s do not decr ...
PDF - ClaimSecure
... the airways which leads to symptoms such as wheezing, coughing, shortness of breath and chest tightness. The Asthma Society of Canada reports that asthma is the leading cause of absenteeism from school and the third leading cause of work loss. In Ontario alone, more than one million people are affec ...
... the airways which leads to symptoms such as wheezing, coughing, shortness of breath and chest tightness. The Asthma Society of Canada reports that asthma is the leading cause of absenteeism from school and the third leading cause of work loss. In Ontario alone, more than one million people are affec ...
Drugs of Abuse
... Antidote or specific therapy Admission for agents that cause delayed deterioration H Heat Rhabdomyolyis Psychosis Is it something else? ...
... Antidote or specific therapy Admission for agents that cause delayed deterioration H Heat Rhabdomyolyis Psychosis Is it something else? ...
ISMP Medication Safety Alert - Institute For Safe Medication Practices
... Oneof themost important ways toprevent medication errors is tolearn about problems that haveoccurred in other organizations and tousethat information toprevent similar problems at your practicesite. To promotesuch aprocess, thefollowing selected items fromtheOctober-December 2011 issues of theISMPMe ...
... Oneof themost important ways toprevent medication errors is tolearn about problems that haveoccurred in other organizations and tousethat information toprevent similar problems at your practicesite. To promotesuch aprocess, thefollowing selected items fromtheOctober-December 2011 issues of theISMPMe ...
Chapter 17 Antipsychotic Agents
... • Chlorpromazine can block apomorphine-induced vomiting. This action is due to dopamine receptor blockade, both centrally(in the chemoreceptor trigger zone of the medulla) and peripherally(on receptors in the stomach). However, large doses of chlorpromazine may depress the vomiting center directly. ...
... • Chlorpromazine can block apomorphine-induced vomiting. This action is due to dopamine receptor blockade, both centrally(in the chemoreceptor trigger zone of the medulla) and peripherally(on receptors in the stomach). However, large doses of chlorpromazine may depress the vomiting center directly. ...
Presentation - Direct Relief
... • Azoles prone to drug interactions through the cytochrome P450 (CYP450) pathway • The CYP450 enzymes are involved in the metabolism of most commonly prescribed drugs • Check package insert for drug interactions when prescribing azoles ...
... • Azoles prone to drug interactions through the cytochrome P450 (CYP450) pathway • The CYP450 enzymes are involved in the metabolism of most commonly prescribed drugs • Check package insert for drug interactions when prescribing azoles ...
DISSOLUTION ENHANCEMENT OF TELMISARTAN BY LIQUISOLID COMPACTS , Research Article
... disintegration time and dissolution test. Fourier transform infrared (FTIR) analysis, differential scanning calorimetry (DSC), X-ray powder diffraction (XRPD) and scanning electron microscopy (SEM) were performed. Results: The results showed that liquisolid formulas exhibited acceptable flowability ...
... disintegration time and dissolution test. Fourier transform infrared (FTIR) analysis, differential scanning calorimetry (DSC), X-ray powder diffraction (XRPD) and scanning electron microscopy (SEM) were performed. Results: The results showed that liquisolid formulas exhibited acceptable flowability ...
Herb-drug interactions
... pressure, thus contraindicated with antihypertensives and stimulants (e.g. caffeine). Black Cohosh (menopausal symptoms but UIC trial negative) – some hepatotoxicity due to adulteration recently; use cautiously. Ginkgo – 2 case reports of interaction with phenelzine; insomnia, headache, irritability ...
... pressure, thus contraindicated with antihypertensives and stimulants (e.g. caffeine). Black Cohosh (menopausal symptoms but UIC trial negative) – some hepatotoxicity due to adulteration recently; use cautiously. Ginkgo – 2 case reports of interaction with phenelzine; insomnia, headache, irritability ...
Pharmacology MCQs: 07/05/02
... b. At normal tissue pH the larger fraction of local anaesthetic in the body fluids will be the uncharged form c. Bupivacaine may cause an apparent cyanosis in some patients d. The duration of action of procaine will be increased in the presence of liver disease e. Local anaesthetic agents block cond ...
... b. At normal tissue pH the larger fraction of local anaesthetic in the body fluids will be the uncharged form c. Bupivacaine may cause an apparent cyanosis in some patients d. The duration of action of procaine will be increased in the presence of liver disease e. Local anaesthetic agents block cond ...
Drug policy provisions from the international drug control Conventions
... burdensome were commonly perceived as a significant limitation on availability10. Some of the substances in Schedule I of the 1961 Convention can be described as difficult to handle because of their pharmacological profile. After being tentatively used for therapeutic purposes, and in some cases com ...
... burdensome were commonly perceived as a significant limitation on availability10. Some of the substances in Schedule I of the 1961 Convention can be described as difficult to handle because of their pharmacological profile. After being tentatively used for therapeutic purposes, and in some cases com ...
Medical treatment for vertigo - ORL
... for vertigo in Belgium is given. The pharmacological properties, contra-indications, side-effects and dosage are discussed for each drug. For more detailed information we refer to textbooks on pharmacology.1-3 1. Acute unilateral vestibular loss For acute unilateral vestibular loss, medical treatmen ...
... for vertigo in Belgium is given. The pharmacological properties, contra-indications, side-effects and dosage are discussed for each drug. For more detailed information we refer to textbooks on pharmacology.1-3 1. Acute unilateral vestibular loss For acute unilateral vestibular loss, medical treatmen ...
here - The Therapeutics Initiative
... study results, and no consistent advantage or disadvantage was observed for mirtazapine. Doses of mirtazapine and comparators varied considerably between trials. Adverse effects: The common and serious adverse effects (from the product monograph) expressed as absolute risk increase over placebo are ...
... study results, and no consistent advantage or disadvantage was observed for mirtazapine. Doses of mirtazapine and comparators varied considerably between trials. Adverse effects: The common and serious adverse effects (from the product monograph) expressed as absolute risk increase over placebo are ...
Drug interaction
A drug interaction is a situation in which a substance (usually another drug) affects the activity of a drug when both are administered together. This action can be synergistic (when the drug's effect is increased) or antagonistic (when the drug's effect is decreased) or a new effect can be produced that neither produces on its own. Typically, interactions between drugs come to mind (drug-drug interaction). However, interactions may also exist between drugs and foods (drug-food interactions), as well as drugs and medicinal plants or herbs (drug-plant interactions). People taking antidepressant drugs such as monoamine oxidase inhibitors should not take food containing tyramine as hypertensive crisis may occur (an example of a drug-food interaction). These interactions may occur out of accidental misuse or due to lack of knowledge about the active ingredients involved in the relevant substances.It is therefore easy to see the importance of these pharmacological interactions in the practice of medicine. If a patient is taking two drugs and one of them increases the effect of the other it is possible that an overdose may occur. The interaction of the two drugs may also increase the risk that side effects will occur. On the other hand, if the action of a drug is reduced it may cease to have any therapeutic use because of under dosage. Notwithstanding the above, on occasion these interactions may be sought in order to obtain an improved therapeutic effect. Examples of this include the use of codeine with paracetamol to increase its analgesic effect. Or the combination of clavulanic acid with amoxicillin in order to overcome bacterial resistance to the antibiotic. It should also be remembered that there are interactions that, from a theoretical standpoint, may occur but in clinical practice have no important repercussions.The pharmaceutical interactions that are of special interest to the practice of medicine are primarily those that have negative effects for an organism. The risk that a pharmacological interaction will appear increases as a function of the number of drugs administered to a patient at the same time.It is possible that an interaction will occur between a drug and another substance present in the organism (i.e. foods or alcohol). Or in certain specific situations a drug may even react with itself, such as occurs with dehydration. In other situations, the interaction does not involve any effect on the drug. In certain cases, the presence of a drug in an individual's blood may affect certain types of laboratory analysis (analytical interference).It is also possible for interactions to occur outside an organism before administration of the drugs has taken place. This can occur when two drugs are mixed, for example, in a saline solution prior to intravenous injection. Some classic examples of this type of interaction include that Thiopentone and Suxamethonium should not be placed in the same syringe and same is true for Benzylpenicillin and Heparin. These situations will all be discussed under the same heading due to their conceptual similarity.Drug interactions may be the result of various processes. These processes may include alterations in the pharmacokinetics of the drug, such as alterations in the absorption, distribution, metabolism, and excretion (ADME) of a drug. Alternatively, drug interactions may be the result of the pharmacodynamic properties of the drug, e.g. the co-administration of a receptor antagonist and an agonist for the same receptor.