Bulletin #88
... Effective October 1, 2001, the EDS criteria for the following products will be as indicated. dihydroergotamine mesylate, nasal spray, 4mg/mL (Migranal-NVR) For treatment of migraines where standard therapy such as an analgesic has failed or cannot be tolerated. naratriptan HCl, tablet, 1mg, 2.5mg (A ...
... Effective October 1, 2001, the EDS criteria for the following products will be as indicated. dihydroergotamine mesylate, nasal spray, 4mg/mL (Migranal-NVR) For treatment of migraines where standard therapy such as an analgesic has failed or cannot be tolerated. naratriptan HCl, tablet, 1mg, 2.5mg (A ...
Treatment of Lipid Disorders
... • Max dose 2.0 gm/day SR niacin (and give folate) • Titrate dose up slowly • Benefit on HDL seen at < 1.5 gms/day; TG effect dose dependent. • Take with meals; pretreat_~1 hour earlier with NSAID • Avoid alcohol (flushing, hepatitis) ...
... • Max dose 2.0 gm/day SR niacin (and give folate) • Titrate dose up slowly • Benefit on HDL seen at < 1.5 gms/day; TG effect dose dependent. • Take with meals; pretreat_~1 hour earlier with NSAID • Avoid alcohol (flushing, hepatitis) ...
Lorcaserin : The Serotonergic Weight Loss Medication
... activating specific nerve cell receptors for serotonin in the appetite centers of the brain. In the case of Belviq, the increased serotonin sends messages of increased feelings of fullness and satisfaction. Researchers at Arena Pharmaceuticals who discovered and developed Belviq say the drug selecti ...
... activating specific nerve cell receptors for serotonin in the appetite centers of the brain. In the case of Belviq, the increased serotonin sends messages of increased feelings of fullness and satisfaction. Researchers at Arena Pharmaceuticals who discovered and developed Belviq say the drug selecti ...
minims amethocaine eye drops
... accompanying reduction of visual acuity or visual loss. To avoid corneal damage, do not exceed the recommended dosage, especially in patients with compromised corneas. Patients should be warned not to rub or touch the eye while anaesthesia persists. The anaesthetised eye should be protected from dus ...
... accompanying reduction of visual acuity or visual loss. To avoid corneal damage, do not exceed the recommended dosage, especially in patients with compromised corneas. Patients should be warned not to rub or touch the eye while anaesthesia persists. The anaesthetised eye should be protected from dus ...
Antimicrobial Potential of Ficus Bengalensis Aerial Roots
... Organization , medicinal plants would be the best source to obtain a variety of drugs. About 80% of individuals from developed countries use medicines, which have compounds derived from medicinal plants. Thus, plants could be investigated to identify their antimicrobial profile, safety and efficacy. ...
... Organization , medicinal plants would be the best source to obtain a variety of drugs. About 80% of individuals from developed countries use medicines, which have compounds derived from medicinal plants. Thus, plants could be investigated to identify their antimicrobial profile, safety and efficacy. ...
presentation
... Analysis of variance was used to compare the positive control vs. placebo at each data point and calculate point estimates of the respective two-sided 95% CI for the difference in effects between use of placebo and moxifloxacin. ...
... Analysis of variance was used to compare the positive control vs. placebo at each data point and calculate point estimates of the respective two-sided 95% CI for the difference in effects between use of placebo and moxifloxacin. ...
Methamphetamine: A Cinical Primer
... • Intensive therapy is the best hope, but the relapse rate is very high ...
... • Intensive therapy is the best hope, but the relapse rate is very high ...
PEDS Medications
... Inform parents that medicine should not be referred to as candy because when they taste they will know it is not candy. ...
... Inform parents that medicine should not be referred to as candy because when they taste they will know it is not candy. ...
PHYSICOCHEMICAL CHARACTERIZATION OF SPRAY DRIED FORMULATION CONTAINING AMORPHOUS DRUG Research Article
... dried technology at optimum processing parameters. These data indicated that using different excipient such as mannitol which is hygroscopic, microcrystalline cellulose, and dibasic calcium phosphate which are water insoluble diluents may cause phase transformation of the drug and consequently affec ...
... dried technology at optimum processing parameters. These data indicated that using different excipient such as mannitol which is hygroscopic, microcrystalline cellulose, and dibasic calcium phosphate which are water insoluble diluents may cause phase transformation of the drug and consequently affec ...
Table 1 - HAL
... Glucuronidation is a major drug metabolic pathway, catalyzed by uridine diphosphate (UDP)-glucuronosyltranferases (UGT). Two main families of UGTs have been identified in humans, namely UGT1A and UGT2 (subdivided in UGT2A and UGT2B) [1, 2]. The UGT 1A family consists of 9 functionally active protein ...
... Glucuronidation is a major drug metabolic pathway, catalyzed by uridine diphosphate (UDP)-glucuronosyltranferases (UGT). Two main families of UGTs have been identified in humans, namely UGT1A and UGT2 (subdivided in UGT2A and UGT2B) [1, 2]. The UGT 1A family consists of 9 functionally active protein ...
Hypersensitivity reactions to anticancer agents: Data mining of the
... Although HSRs are considered uncommon during treatment with anticancer agents, platinum agents, taxanes, procarbazine, asparaginase, and epipodophyllotoxins are thought to increase the susceptibility to such reactions [1-5]. Previously [7], and in this study, pharmacoepidemiological analyses were pe ...
... Although HSRs are considered uncommon during treatment with anticancer agents, platinum agents, taxanes, procarbazine, asparaginase, and epipodophyllotoxins are thought to increase the susceptibility to such reactions [1-5]. Previously [7], and in this study, pharmacoepidemiological analyses were pe ...
03/11/11 - Magellan Rx Management
... A diagnosis of Attention Deficit Hyperactivity Disorder (ADHD; DSM-IV®) for an adult implies the presence of hyperactiveimpulsive or inattentive symptoms that caused impairment and were present before age 7 years. As an adult, the symptoms must cause clinically significant impairment, e.g., in socia ...
... A diagnosis of Attention Deficit Hyperactivity Disorder (ADHD; DSM-IV®) for an adult implies the presence of hyperactiveimpulsive or inattentive symptoms that caused impairment and were present before age 7 years. As an adult, the symptoms must cause clinically significant impairment, e.g., in socia ...
a novel approach using hydrotropic solubalization technique
... Objective: Analysis of drug utilized the organic solvent which are costlier, toxic, and causing environment pollution. Hydrotropic solution may be a proper choice to preclude the use of organic solvents so that an attempt has been made to develop simple, accurate, novel, safe and precise spectrophot ...
... Objective: Analysis of drug utilized the organic solvent which are costlier, toxic, and causing environment pollution. Hydrotropic solution may be a proper choice to preclude the use of organic solvents so that an attempt has been made to develop simple, accurate, novel, safe and precise spectrophot ...
Introduction - African Journals Online
... 2003). However, health care programmes are being strengthened, the availability of drugs is being regulated more extensively, and policy makers are increasingly aware of the need of improved drug prescription behaviour (WHO, 2001). Adopting a surveillance system for antibacterial use has therefore b ...
... 2003). However, health care programmes are being strengthened, the availability of drugs is being regulated more extensively, and policy makers are increasingly aware of the need of improved drug prescription behaviour (WHO, 2001). Adopting a surveillance system for antibacterial use has therefore b ...
DEPRESSION: MASTER
... paroxetine 20 mg a day for depression and panic disorder reports that he missed several doses and feels extremely anxious, with nausea, and tingling sensations in arms and legs. ...
... paroxetine 20 mg a day for depression and panic disorder reports that he missed several doses and feels extremely anxious, with nausea, and tingling sensations in arms and legs. ...
Antiparkinsonian drugs_E
... DA-ergic activity with levodopa and DA agonists have been successful in alleviating many of the clinical features of the disorder. An alternative but complementary approach has been to restore the normal balance of cholinergic and dopaminergic influences on the basal ganglia with antimuscarinic drug ...
... DA-ergic activity with levodopa and DA agonists have been successful in alleviating many of the clinical features of the disorder. An alternative but complementary approach has been to restore the normal balance of cholinergic and dopaminergic influences on the basal ganglia with antimuscarinic drug ...
Evaluating Drugs Used To Treat: Constipation
... Age – Constipation is more common in older people. This is in part because slowing of the bowel functions is a natural part of the aging process and because the elderly are often on medications that slow the gastrointestinal tract. Changes in routine – Many people become constipated while traveling, ...
... Age – Constipation is more common in older people. This is in part because slowing of the bowel functions is a natural part of the aging process and because the elderly are often on medications that slow the gastrointestinal tract. Changes in routine – Many people become constipated while traveling, ...
effects of dust formulations of three entomophatogenic fungal
... Methanol extract of O. stamineus was shown to be more effective in affecting phase II hepatic drug metabolizing enzymes, UGT and GST activities as compared to phase I hepatic drug metabolizing enzyme, aminopyrine Ndemethylase activity in SD rats. At the higher concentration of O. stamineus such as 0 ...
... Methanol extract of O. stamineus was shown to be more effective in affecting phase II hepatic drug metabolizing enzymes, UGT and GST activities as compared to phase I hepatic drug metabolizing enzyme, aminopyrine Ndemethylase activity in SD rats. At the higher concentration of O. stamineus such as 0 ...
Bulletin #94
... valganciclovir HCl, tablet, 450mg (Valcyte-HLR) For treatment of retinitis arising from CMV infection in patients with HIV infection. Effective April 1, 2003 the following product will be covered under the same Exception Drug Status criteria as the currently listed forms/strengths. efavirenz, tablet ...
... valganciclovir HCl, tablet, 450mg (Valcyte-HLR) For treatment of retinitis arising from CMV infection in patients with HIV infection. Effective April 1, 2003 the following product will be covered under the same Exception Drug Status criteria as the currently listed forms/strengths. efavirenz, tablet ...
The role of metabolic inhibition
... pollutants (Nebert & Russell, 2002). CYP’s are mostly involved in metabolism of chemicals and but could also activate the pre-carcinogens metabolically (Bozina et al. 2009). As food having different xenobiotics is digested in gastrointestinal tract, the intestinal micro-flora are also involved in xe ...
... pollutants (Nebert & Russell, 2002). CYP’s are mostly involved in metabolism of chemicals and but could also activate the pre-carcinogens metabolically (Bozina et al. 2009). As food having different xenobiotics is digested in gastrointestinal tract, the intestinal micro-flora are also involved in xe ...
PREPARATION AND COMPARATIVE EVALUATIONOF LIQUISOLID COMPACT AND SOLID
... Candesartan cilexetil (CC) is a newer class of angiotensin II receptor antagonist used for the treatment of hypertension, heart failure, myocardial infarction and diabetic nephropathy.The solubility of the CC is very poor and its oral bioavailability is only 15%. Objective: The aim of the present st ...
... Candesartan cilexetil (CC) is a newer class of angiotensin II receptor antagonist used for the treatment of hypertension, heart failure, myocardial infarction and diabetic nephropathy.The solubility of the CC is very poor and its oral bioavailability is only 15%. Objective: The aim of the present st ...
Amphetamine-Type Stimulants in Latin America
... In Latin America, cannabis, cocaine and their derivatives continue to be the most significant drug problems both in terms of use and in terms of trafficking. However, although still low, especially when compared to other regions of the world like Asia, use of amphetamine-type stimulants seems to be ...
... In Latin America, cannabis, cocaine and their derivatives continue to be the most significant drug problems both in terms of use and in terms of trafficking. However, although still low, especially when compared to other regions of the world like Asia, use of amphetamine-type stimulants seems to be ...
Date Rape Drugs - Rape and Abuse Crisis Service
... GHB (Gamma Hydroxy Butyrate) • GHB is being widely used as a date rape drug. In the past, Rohypnol was the most frequently used in this way, but we are now seeing more instances of date rapes committed with the assistance of GHB. It is easily slipped into a drink, and can take effect within 3-7 minu ...
... GHB (Gamma Hydroxy Butyrate) • GHB is being widely used as a date rape drug. In the past, Rohypnol was the most frequently used in this way, but we are now seeing more instances of date rapes committed with the assistance of GHB. It is easily slipped into a drink, and can take effect within 3-7 minu ...
BHIVA and HIVPA response to proposal to reclassify Pirinase 250213
... people with HIV infection (many of whom also suffer from allergic rhinitis) and cobicistat (another potent CYP 3A4 inhibitor which has the same potentiating effect on fluticasone) is due to be launched in the UK early in 2013. There is recent evidence to demonstrate that the ritonavir/fluticasone in ...
... people with HIV infection (many of whom also suffer from allergic rhinitis) and cobicistat (another potent CYP 3A4 inhibitor which has the same potentiating effect on fluticasone) is due to be launched in the UK early in 2013. There is recent evidence to demonstrate that the ritonavir/fluticasone in ...
Drug interaction
A drug interaction is a situation in which a substance (usually another drug) affects the activity of a drug when both are administered together. This action can be synergistic (when the drug's effect is increased) or antagonistic (when the drug's effect is decreased) or a new effect can be produced that neither produces on its own. Typically, interactions between drugs come to mind (drug-drug interaction). However, interactions may also exist between drugs and foods (drug-food interactions), as well as drugs and medicinal plants or herbs (drug-plant interactions). People taking antidepressant drugs such as monoamine oxidase inhibitors should not take food containing tyramine as hypertensive crisis may occur (an example of a drug-food interaction). These interactions may occur out of accidental misuse or due to lack of knowledge about the active ingredients involved in the relevant substances.It is therefore easy to see the importance of these pharmacological interactions in the practice of medicine. If a patient is taking two drugs and one of them increases the effect of the other it is possible that an overdose may occur. The interaction of the two drugs may also increase the risk that side effects will occur. On the other hand, if the action of a drug is reduced it may cease to have any therapeutic use because of under dosage. Notwithstanding the above, on occasion these interactions may be sought in order to obtain an improved therapeutic effect. Examples of this include the use of codeine with paracetamol to increase its analgesic effect. Or the combination of clavulanic acid with amoxicillin in order to overcome bacterial resistance to the antibiotic. It should also be remembered that there are interactions that, from a theoretical standpoint, may occur but in clinical practice have no important repercussions.The pharmaceutical interactions that are of special interest to the practice of medicine are primarily those that have negative effects for an organism. The risk that a pharmacological interaction will appear increases as a function of the number of drugs administered to a patient at the same time.It is possible that an interaction will occur between a drug and another substance present in the organism (i.e. foods or alcohol). Or in certain specific situations a drug may even react with itself, such as occurs with dehydration. In other situations, the interaction does not involve any effect on the drug. In certain cases, the presence of a drug in an individual's blood may affect certain types of laboratory analysis (analytical interference).It is also possible for interactions to occur outside an organism before administration of the drugs has taken place. This can occur when two drugs are mixed, for example, in a saline solution prior to intravenous injection. Some classic examples of this type of interaction include that Thiopentone and Suxamethonium should not be placed in the same syringe and same is true for Benzylpenicillin and Heparin. These situations will all be discussed under the same heading due to their conceptual similarity.Drug interactions may be the result of various processes. These processes may include alterations in the pharmacokinetics of the drug, such as alterations in the absorption, distribution, metabolism, and excretion (ADME) of a drug. Alternatively, drug interactions may be the result of the pharmacodynamic properties of the drug, e.g. the co-administration of a receptor antagonist and an agonist for the same receptor.