INVESTIGATION OF ANALGESIC AND ANTI-INFLAMMATORY POTENTIAL OF ETHANOLIC WIGHTIANA Research Article
... antibody interactions and thermal or other physical injury. Each type of stimulus provokes a characteristic pattern of response that represents a relatively minor variation. The response usually is accompanied by some familiar clinical signs such as erythema, edema, hyperalgesia and pain. A large nu ...
... antibody interactions and thermal or other physical injury. Each type of stimulus provokes a characteristic pattern of response that represents a relatively minor variation. The response usually is accompanied by some familiar clinical signs such as erythema, edema, hyperalgesia and pain. A large nu ...
EFFECT OF NICORANDIL ON BASAL GLUCOSE LEVELS AND AFTER GLUCOSE... NORMAL EUGLYCEMIC ALBINO WISTAR RATS
... Nicorandil treated group, i.e. 126.65mg%. Basal levels of CBG were almost double than that of control readings i.e. around 65.5mg%. This can be explained on the basis that Nicorandil being an ATP sensitive potassium channel opener inhibited the basal secretion of insulin in absence of glucose challe ...
... Nicorandil treated group, i.e. 126.65mg%. Basal levels of CBG were almost double than that of control readings i.e. around 65.5mg%. This can be explained on the basis that Nicorandil being an ATP sensitive potassium channel opener inhibited the basal secretion of insulin in absence of glucose challe ...
Monoamine Oxidase Inhibitors (MAOIs)
... The monoamine oxidase inhibitors (MAOIs) represent a group of older antidepressants that have limited, but selective, use for treatment of depression. These agents have been replaced by newer and safer agents such as selective serotonin reuptake inhibitors (SSRIs) as well as other non-SSRIs such as ...
... The monoamine oxidase inhibitors (MAOIs) represent a group of older antidepressants that have limited, but selective, use for treatment of depression. These agents have been replaced by newer and safer agents such as selective serotonin reuptake inhibitors (SSRIs) as well as other non-SSRIs such as ...
Unit- 2 - Shree Medical and Technical College
... effect of temperature in non-aqueous titration; indicators in non-aqueous titration; end point detection by potentiometry, titration of alkali metal salts of organic acid, amines and amine salts of organic acid, halogen acid salts of bases and acidic substances, preparation & standardization of stan ...
... effect of temperature in non-aqueous titration; indicators in non-aqueous titration; end point detection by potentiometry, titration of alkali metal salts of organic acid, amines and amine salts of organic acid, halogen acid salts of bases and acidic substances, preparation & standardization of stan ...
The heart of Daphnia magna: effects of four
... that crustaceans are insensitive to organic Ca2q channel blockers, but sensitive to inorganic Ca2q channel blocker, such as Sr2q (Jeziorski et al., 1998), suggesting the presence of Ca2q channels in D. magna heart. These data support the suggestion that D. magna heart might have verapamil receptors ...
... that crustaceans are insensitive to organic Ca2q channel blockers, but sensitive to inorganic Ca2q channel blocker, such as Sr2q (Jeziorski et al., 1998), suggesting the presence of Ca2q channels in D. magna heart. These data support the suggestion that D. magna heart might have verapamil receptors ...
What is the prognosis for new centrally-acting anti
... In this review, we discuss the challenges for the development of centrally-acting anti-obesity drugs arising from a conservative regulatory environment, difficult marketing conditions and unrealistic patient expectations. We also critically assess the three drug candidates that are currently at the p ...
... In this review, we discuss the challenges for the development of centrally-acting anti-obesity drugs arising from a conservative regulatory environment, difficult marketing conditions and unrealistic patient expectations. We also critically assess the three drug candidates that are currently at the p ...
Factors that affect mass transport from drug eluting stents into the
... transport from a DES is a powerful means of evaluating the effectiveness of stent design before a stent is taken to clinical trial. This provides the manufacturer with a level of controllability, enabling the production of a DES that will offer sufficient dosage of therapeutic agents to the injured ...
... transport from a DES is a powerful means of evaluating the effectiveness of stent design before a stent is taken to clinical trial. This provides the manufacturer with a level of controllability, enabling the production of a DES that will offer sufficient dosage of therapeutic agents to the injured ...
Morphine Facts and Tips
... How is it used? Oral (PO): route of choice; 30mg=10mg IM in repeated doses because first pass effect of hepatic metabolism (portal circulation from the gut goes to liver where part of the dose is metabolized); immediate release preparations are effective for breakthrough pain to titrate doses and fo ...
... How is it used? Oral (PO): route of choice; 30mg=10mg IM in repeated doses because first pass effect of hepatic metabolism (portal circulation from the gut goes to liver where part of the dose is metabolized); immediate release preparations are effective for breakthrough pain to titrate doses and fo ...
Urine Drug Testing Clinical Practice in The Art
... immunoassay testing in favor of panels utilizing more definitive GC/MS or LC/MS testing. The UDT method chosen should be a function of the question that needs to be answered. It is important that clinicians understand the methods for UDT in order to correctly interpret results.8 ...
... immunoassay testing in favor of panels utilizing more definitive GC/MS or LC/MS testing. The UDT method chosen should be a function of the question that needs to be answered. It is important that clinicians understand the methods for UDT in order to correctly interpret results.8 ...
Drugs for constipation and Diarrhoea
... stool, accumulates fluids and fatty substance thus softening the stool. • Administered orally or as retention enema. • Should not be given with liquid paraffin, because increase absorption of it. ...
... stool, accumulates fluids and fatty substance thus softening the stool. • Administered orally or as retention enema. • Should not be given with liquid paraffin, because increase absorption of it. ...
Epinephrine Injection, USP
... Epinephrine contains sodium bisulfite, a sulfite that may cause allergic-type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people. The overall prevalence of sulfite sensitivity in the general population is unknown and probabl ...
... Epinephrine contains sodium bisulfite, a sulfite that may cause allergic-type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people. The overall prevalence of sulfite sensitivity in the general population is unknown and probabl ...
Dementia
... Non-ionized and protein-bound Small changes in pH greatly alter the availability of the drug ...
... Non-ionized and protein-bound Small changes in pH greatly alter the availability of the drug ...
Pharmaceutical excipients and pediatric formulations
... Similarly, distribution of drugs can be severely impacted in pediatric reactions. The interactions thus produced due to drug-excipient, sub-population as the amount of body water is significantly higher excipient-excipient, or excipient-intracellular chemicals can be in neonates (85 percent) as comp ...
... Similarly, distribution of drugs can be severely impacted in pediatric reactions. The interactions thus produced due to drug-excipient, sub-population as the amount of body water is significantly higher excipient-excipient, or excipient-intracellular chemicals can be in neonates (85 percent) as comp ...
HERBAL TREATMENT FOR URINARY STONES
... The problem of urinary stones or calculi is a very ancient one and many remedies have been employed during the ages these stones are found in all parts of the urinary tract, the kidney, the ureters and the urinary bladder and may vary considerably in size, Linacre, who had founded the college of phy ...
... The problem of urinary stones or calculi is a very ancient one and many remedies have been employed during the ages these stones are found in all parts of the urinary tract, the kidney, the ureters and the urinary bladder and may vary considerably in size, Linacre, who had founded the college of phy ...
Drugs that may exacerbate psoriasis
... about the factors which will precipitate a recurrence of psoriasis. These include infection, HIV, trauma, pregnancy and drugs.1,2 This review concentrates on those drugs which have been clearly shown, or are widely reputed, to make psoriasis worse. There is insufficient clinical evidence to justify t ...
... about the factors which will precipitate a recurrence of psoriasis. These include infection, HIV, trauma, pregnancy and drugs.1,2 This review concentrates on those drugs which have been clearly shown, or are widely reputed, to make psoriasis worse. There is insufficient clinical evidence to justify t ...
Toxicologic Pathology - Ocular Therapeutix, Inc.
... area least likely to damage those structures. Anatomical differences within this region make implantation much more difficult in rabbits compared to larger species, discussed below. The structures of polymeric devices for controlled, sustained release are classified as nonbiodegradable and biodegrad ...
... area least likely to damage those structures. Anatomical differences within this region make implantation much more difficult in rabbits compared to larger species, discussed below. The structures of polymeric devices for controlled, sustained release are classified as nonbiodegradable and biodegrad ...
RUBUS ELLIPTICUS SMITH. LEAF METHANOL EXTRACT Research Article
... Use of medicinal plants as a source of relief and cure from various illness is as old as humankind. Even today, medicinal plants provide a cheap source of drugs for majority of world’s population. Plants have provided and will continue to provide not only directly usable drugs, but also a great vari ...
... Use of medicinal plants as a source of relief and cure from various illness is as old as humankind. Even today, medicinal plants provide a cheap source of drugs for majority of world’s population. Plants have provided and will continue to provide not only directly usable drugs, but also a great vari ...
FORMULATION AND EVALUATION OF MELT-IN-MOUTH TABLETS OF CONTAINING MULTICOMPONENT INCLUSION COMPLEX
... anytime. They are suitable for geriatric and pediatric patients who find it difficult to swallow solid oral dosage forms. They are also most suitable for drugs that undergo extensive first pass metabolism. The benefits, in terms of patient compliance, rapid onset of action as the drug goes directly ...
... anytime. They are suitable for geriatric and pediatric patients who find it difficult to swallow solid oral dosage forms. They are also most suitable for drugs that undergo extensive first pass metabolism. The benefits, in terms of patient compliance, rapid onset of action as the drug goes directly ...
Inhibition and induction of human cytochrome P450 (CYP) enzymes
... A phenom enon that cannot be overemphasized in the ® eld of xenobiotic metabolism is interindividual variability, which results in very individualized patterns of enzyme composition and hence metabolic activities. Permanent determinants causing variability are genetic factors, which result in pharma ...
... A phenom enon that cannot be overemphasized in the ® eld of xenobiotic metabolism is interindividual variability, which results in very individualized patterns of enzyme composition and hence metabolic activities. Permanent determinants causing variability are genetic factors, which result in pharma ...
EPILEPSY
... The two main categories of seizures include Partial seizures – no loss of consciousness and Generalized seizures – loss of consciousness ...
... The two main categories of seizures include Partial seizures – no loss of consciousness and Generalized seizures – loss of consciousness ...
Delirium - Canadian Society of Hospital Pharmacists
... Well absorbed, t1/2 =60-80 hours (+/- food) Mostly cleared via tubular secretion with slight metabolism by CYP450 (no significant effect) ...
... Well absorbed, t1/2 =60-80 hours (+/- food) Mostly cleared via tubular secretion with slight metabolism by CYP450 (no significant effect) ...
diuretics
... gradient across the apical membrane and other compensatory mechanisms lead to some increase in the urine concentration of all the inorganic ions. The increased renal interstitial blood flow removes solutes from the normally hypertonic interstitial fluid, thus partially counteracting the countercurre ...
... gradient across the apical membrane and other compensatory mechanisms lead to some increase in the urine concentration of all the inorganic ions. The increased renal interstitial blood flow removes solutes from the normally hypertonic interstitial fluid, thus partially counteracting the countercurre ...
RELEVANT ACUTE TRUST LOGO
... Severe digitalis toxicity has been seen within days of starting ciclosporin in several patients taking digoxin. When statins are concurrently administered with ciclosporin, their dosage should be reduced according to their SPC. Statin therapy needs to be temporarily withheld or discontinued in p ...
... Severe digitalis toxicity has been seen within days of starting ciclosporin in several patients taking digoxin. When statins are concurrently administered with ciclosporin, their dosage should be reduced according to their SPC. Statin therapy needs to be temporarily withheld or discontinued in p ...
Glossary - CHRISTUS Health
... Drug or Device Accountability Records (DAR) - Required documentation for material accountability, quantity used and left over, and date of disposal. Drug Product - A finished dosage form (e.g. table, capsule, or solution) that contains active drug ingredient usually combined with inactive ingredient ...
... Drug or Device Accountability Records (DAR) - Required documentation for material accountability, quantity used and left over, and date of disposal. Drug Product - A finished dosage form (e.g. table, capsule, or solution) that contains active drug ingredient usually combined with inactive ingredient ...
Drug interaction
A drug interaction is a situation in which a substance (usually another drug) affects the activity of a drug when both are administered together. This action can be synergistic (when the drug's effect is increased) or antagonistic (when the drug's effect is decreased) or a new effect can be produced that neither produces on its own. Typically, interactions between drugs come to mind (drug-drug interaction). However, interactions may also exist between drugs and foods (drug-food interactions), as well as drugs and medicinal plants or herbs (drug-plant interactions). People taking antidepressant drugs such as monoamine oxidase inhibitors should not take food containing tyramine as hypertensive crisis may occur (an example of a drug-food interaction). These interactions may occur out of accidental misuse or due to lack of knowledge about the active ingredients involved in the relevant substances.It is therefore easy to see the importance of these pharmacological interactions in the practice of medicine. If a patient is taking two drugs and one of them increases the effect of the other it is possible that an overdose may occur. The interaction of the two drugs may also increase the risk that side effects will occur. On the other hand, if the action of a drug is reduced it may cease to have any therapeutic use because of under dosage. Notwithstanding the above, on occasion these interactions may be sought in order to obtain an improved therapeutic effect. Examples of this include the use of codeine with paracetamol to increase its analgesic effect. Or the combination of clavulanic acid with amoxicillin in order to overcome bacterial resistance to the antibiotic. It should also be remembered that there are interactions that, from a theoretical standpoint, may occur but in clinical practice have no important repercussions.The pharmaceutical interactions that are of special interest to the practice of medicine are primarily those that have negative effects for an organism. The risk that a pharmacological interaction will appear increases as a function of the number of drugs administered to a patient at the same time.It is possible that an interaction will occur between a drug and another substance present in the organism (i.e. foods or alcohol). Or in certain specific situations a drug may even react with itself, such as occurs with dehydration. In other situations, the interaction does not involve any effect on the drug. In certain cases, the presence of a drug in an individual's blood may affect certain types of laboratory analysis (analytical interference).It is also possible for interactions to occur outside an organism before administration of the drugs has taken place. This can occur when two drugs are mixed, for example, in a saline solution prior to intravenous injection. Some classic examples of this type of interaction include that Thiopentone and Suxamethonium should not be placed in the same syringe and same is true for Benzylpenicillin and Heparin. These situations will all be discussed under the same heading due to their conceptual similarity.Drug interactions may be the result of various processes. These processes may include alterations in the pharmacokinetics of the drug, such as alterations in the absorption, distribution, metabolism, and excretion (ADME) of a drug. Alternatively, drug interactions may be the result of the pharmacodynamic properties of the drug, e.g. the co-administration of a receptor antagonist and an agonist for the same receptor.