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DNA - The Double Helix
DNA - The Double Helix

... double helix (color the title black), which is like a twisted ladder. The sides of the ladder are made of alternating sugar and phosphate molecules. The sugar is Deoxyribose. Color all the phosphates pink (one is labeled with a "p"). Color all the Deoxyribose a LIGHT blue (one is labeled with a "D") ...
Genetics, DNA and Protein Synthesis Study Guide
Genetics, DNA and Protein Synthesis Study Guide

... double helix DNA replication RNA ribose nucleotide base-pairing rules complementary uracil adenine ...
dna replication activity
dna replication activity

... Once you have been “signed off” to create, you replicate on of the DNA models that your lab group created. 1. Use the diagram at the bottom of the page to record your DNA sequence (both strands), by writing down the first letter of each base, with its complementary base (choose only one of the model ...
1 SUPPLEMENTARY DATA DNAproDB: an interactive
1 SUPPLEMENTARY DATA DNAproDB: an interactive

... Calicheamicin gene Cluster (CalC), which binds with a single helix in the minor groove and few other contacts. The complexes with PDB IDs 1J46 (5) and 3U2B (6) contain proteins that predominantly bind with two helices and several loop contacts in the minor groove. ...
Molecular Bio Questions2
Molecular Bio Questions2

... c) The primase adds a short RNA primer to serve as a starting point for the DNA polymerase to add new bases. d) DNA replication is a semi-conservative process, where one strand serves as a template for the synthesis of a complementary strand. e) The incoming nucleotide triphosphate is covalently att ...
Restriction Enzyme Digestion
Restriction Enzyme Digestion

... companion modification enzyme (DNA methyltransferasemethylase) that protects their own DNA from cleavage. • These enzymes recognize the same DNA sequence as the restriction enzyme they accompany, but instead of cleaving the sequence, they disguise it by methylating one of the bases in each DNA stran ...
DNA and RNA
DNA and RNA

... G=C – Only explanation is that T pairs with A and C pairs with G – If a DNA sample is 20% A, what % will C be? • That’s right . . . 30% (20% A = 20% T, leaves 60% for G and C, 30% each) ...
Some Replication Questions
Some Replication Questions

... 1. Prior to the work of Meselson and Stahl (1958), three models regarding the mode of DNA replication prevailed. Describe conservative, semi-conservative and dispersive replication. 2. Describe and explain the Meselson and Stahl experiment which provided the evidence that DNA replication did proceed ...
Dna - Quia
Dna - Quia

... 2. Phosphate molecules that alternate with sugar ...
Introduction to DNA - Mrs. Rugiel`s Webpage
Introduction to DNA - Mrs. Rugiel`s Webpage

... cell division and transfer their genetic information to new chromosomes. Scientists also understand how chromosomes in the cell nucleus can direct the formation of specific proteins outside the nucleus. In this investigation, you will:  Learn the names of the molecules which make up DNA  Use model ...
DNA Fingerprinting
DNA Fingerprinting

... Add DNA + primers + nucleotides (G,A,T,C) + DNA polymerase. Heat DNA (separate the strands) Cool DNA (primers anneal and DNA polymerase assembles new strand) 1 CYCLE = two complete identical copies of DNA ...
Nucleic acid chemistry 1..Denaturation, renaturation, hybridisation
Nucleic acid chemistry 1..Denaturation, renaturation, hybridisation

... relative contributions : ...
The MOLECULES of LIFE
The MOLECULES of LIFE

... The minor groove of A-form DNA is wide and shallow, whereas the Z-form minor grove is narrow. The major groove of A-form DNA is deep and narrow, whereas the Z-form major groove is relatively shallow. In A-form DNA the base pairs are tilted to the helical axis, whereas the Z-form base pairs are nearl ...
Lecture 6: DNA and molecular genetics
Lecture 6: DNA and molecular genetics

... • information for living organisms is encoded in a four letter code in the sequence of a very long molecule called deoxyribonucleic acid (DNA) • DNA consists of two strands twisted around each other to form a double helix • Most of our DNA is stored in the nucleus of cells although some DNA exists i ...
Laboratory in Fundamentals of Molecular Biology
Laboratory in Fundamentals of Molecular Biology

... The process of extracting DNA from a cell is the first step for many laboratory procedures in molecular biology. The scientist must be able to separate DNA from the unwanted substances of the cell gently enough so that the DNA is not sheared into smaller pieces or degraded. Such shearing – breaking ...
DNA - Faperta UGM
DNA - Faperta UGM

... Gadjah Mada University ...
8.4 Transcription
8.4 Transcription

... • Still made of sugar (ribose), phosphate group and nitrogenous base ...
DNA Barcoding
DNA Barcoding

... Adding to the complexity: immature, damaged or incomplete specimen may make identification impossible. ...
AP Biology Unit 1 History of DNA WebQuest 1. Friedrich (Fritz
AP Biology Unit 1 History of DNA WebQuest 1. Friedrich (Fritz

... http://www.dnai.org/timeline/index.html Watch “Chargaff’s Ratios.” Chargaff used relative proportions of bases in DNA to come up with his rules for base pairing. What are four sources of DNA that he used? http://fig.cox.miami.edu/~cmallery/150/gene/chargaff.htm Adenine (A) pairs with _____________ G ...
Document
Document

... Cells Divide by the Process of Mitosis Cell with a single copy of DNA DNA replicates to form chromosomes (two copies of DNA) Chromosomes line up in the middle of the cell Chromosomes are split. Half of each chromosome travels to either end of the cell. The cell divides to form two new cells with th ...
2017 Wisconsin Livestock Identification Consortium Wisconsin State
2017 Wisconsin Livestock Identification Consortium Wisconsin State

... Upon receipt of this form and full payment WLIC will ship items selected below with all forms/instruction sheets to use for DNA samples. Please specify the type of livestock tag you are ordering, be specific on species. Livestock must be identified in the exhibitor’s name or in the immediate family ...
Chapter 12 DNA & RNA
Chapter 12 DNA & RNA

... • X-shaped pattern shows that the strands in DNA are twisted around each other like the coils of a spring – a shape known as a helix – the X suggests that there are two strands in the structure – Other clues suggest that the nitrogenous bases are near the center of the molecule ...
Ch. 10: Nucleic Acids and Protein Synthesis
Ch. 10: Nucleic Acids and Protein Synthesis

... 2) In the nucleus of the cell, free-floating nucleotides bond to the “unzipped” portion of the DNA molecule. 3) The replication is complete after an enzyme called DNA polymerase bonds all nucleotides together forming 2 DNA molecules, both with one “old strand” and one “new strand.” ...
Ch. 10: Nucleic Acids and Protein Synthesis
Ch. 10: Nucleic Acids and Protein Synthesis

... 2) In the nucleus of the cell, free-floating nucleotides bond to the “unzipped” portion of the DNA molecule. 3) The replication is complete after an enzyme called DNA polymerase bonds all nucleotides together forming 2 DNA molecules, both with one “old strand” and one “new strand.” ...
Cell Controls
Cell Controls

... from each other? 2. Are the phosphates molecules directly across from each other? 3. What makes up the backbone? 4. How many adenine – thymine rungs did you make? 5. How many cytosine – guanine rungs did you make? 6. Is the arrangement of the bases of your ladder the same as others in the class? Why ...
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DNA nanotechnology



DNA nanotechnology is the design and manufacture of artificial nucleic acid structures for technological uses. In this field, nucleic acids are used as non-biological engineering materials for nanotechnology rather than as the carriers of genetic information in living cells. Researchers in the field have created static structures such as two- and three-dimensional crystal lattices, nanotubes, polyhedra, and arbitrary shapes, as well as functional devices such as molecular machines and DNA computers. The field is beginning to be used as a tool to solve basic science problems in structural biology and biophysics, including applications in crystallography and spectroscopy for protein structure determination. Potential applications in molecular scale electronics and nanomedicine are also being investigated.The conceptual foundation for DNA nanotechnology was first laid out by Nadrian Seeman in the early 1980s, and the field began to attract widespread interest in the mid-2000s. This use of nucleic acids is enabled by their strict base pairing rules, which cause only portions of strands with complementary base sequences to bind together to form strong, rigid double helix structures. This allows for the rational design of base sequences that will selectively assemble to form complex target structures with precisely controlled nanoscale features. A number of assembly methods are used to make these structures, including tile-based structures that assemble from smaller structures, folding structures using the DNA origami method, and dynamically reconfigurable structures using strand displacement techniques. While the field's name specifically references DNA, the same principles have been used with other types of nucleic acids as well, leading to the occasional use of the alternative name nucleic acid nanotechnology.
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