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METHOTREXAT “EBEWE” 10 mg/ml and 100 mg/ml
METHOTREXAT “EBEWE” 10 mg/ml and 100 mg/ml

... In severe, generalized, therapy-resistant psoriasis vulgaris including psoriatic arthritis and other autoimmunopathies: It is recommended that a test dose of 5-10 mg may be parenterally administered one week prior to initiation of therapy, in order to detect idiosyncratic adverse effects. The recomm ...
CLINICAL TRIAL FACT SHEET - International Myeloma Foundation
CLINICAL TRIAL FACT SHEET - International Myeloma Foundation

... Cycles 1 through 4: Placebo capsule matching the 3 mg ixazomib capsule orally, once daily, on days 1, 8, and 15 of a 28-day cycle. Cycles 5–26: Placebo capsule matching the 3 mg or 4 mg ixazomib capsule orally, once daily, on days 1, 8, and 15 of a 28-day cycle. Patients experiencing AEs attributed ...
Understanding MDMA - Ohio Northern University
Understanding MDMA - Ohio Northern University

... and other related compounds to be used for psychological warfare.3 These experiments carried out by the United States government were the first studies of the toxicology of MDMA.2 MK Ultra was the study of psychoactive agents and their use in military situations. MK Ultra has since been declassified ...
Limitations of Trauma-Focused Therapies for Treating
Limitations of Trauma-Focused Therapies for Treating

... responses. These therapies provoke very high anxiety in participants, if not panic, expecting  that a desensitization process will take place on its own like in prolonged exposure, PE (Foa &  Meadows, 1997). Traditionally, immersion (newly renamed prolonged exposure) requires that  the therapist per ...
Master-Thesis
Master-Thesis

... From bench to bedside – drug development seems to be a simple process. Closer inspections show, however, that drug development is an exceedingly complex exercise in which many issues have to be taken into account. From the idea to develop a new drug through to the receipt of a marketing authorisatio ...
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... (not available in the United States).24 In open-label, uncontrolled studies, agents shown to suppress ACE inhibitor-induced cough include the ␥-aminobutyric acid agonist baclofen,25 the thromboxane synthetase inhibitor ozagrel,26 and aspirin, 500 mg/d (low-dose therapy with aspirin was found to be i ...
Depakote Tablets (divalproex sodium) Tablet [Abbott Laboratories] BOX WARNING HEPATOTOXICITY
Depakote Tablets (divalproex sodium) Tablet [Abbott Laboratories] BOX WARNING HEPATOTOXICITY

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... disorder. Most CAs have at least three rings in their chemical structure. They include the traditional tricyclic antidepressants (TCAs) imipramine, desipramine, amitriptyline, nortriptyline, doxepin, trimipramine, protriptyline, and clomipramine, as well as other cyclic compounds such as maprotiline ...
Intuitive Eating in theTreatment of Eating Disorders
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... • An appropriate diagnosis/indication for the requested medication, • An appropriate dose of medication based on age and indication, • Documented trial of 2 formulary agents for an adequate duration have not been effective or tolerated OR • All other formulary medications are contraindicated based o ...
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SUMMARY OF PRODUCT CHARACTERISTICS 1 NAME OF THE

... Posology and method of administration Methylthioninium Chloride EmBlue may be administered orally or by intravenous (IV) injection. In the treatment of acute methaemoglobinaemia, the IV route of administration is usually preferred because it provides a more rapid onset of effect. However, in large d ...
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... Soluble penicillin G is excreted in breast milk. Caution should be exercised when penicillin G benzathine is administered to a nursing woman. Carcinogenesis, Mutagenesis, Impairment of Fertility No long-term animal studies have been conducted with this drug. Pediatric Use (See INDICATIONS AND USAGE ...
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... variety of symptoms and associated diagnoses. According to Bessel van der Kolk, some form of this condition has been recognized in medical research since 1889 (van der Kolk, n.d., p. 7). When thinking about PTSD, it is often the symptoms of intrusive memories and hyper-arousal that come to mind. How ...
Acute Nonvariceal Upper Gastrointestinal Bleeding: Endoscopic
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... recently decreasing in America because of increasing administration of antibiotics in general or as specific therapy for chronic H pylori infection [38]. About 15% of patients who have H pylori infection develop duodenal ulcers. The virulent bacterial strain that contains the cagA gene is strongly as ...
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... events, a narrow therapeutic index makes it a less than optimal antithrombin for this class of patients. Like their parent anticoagulant, i.e. standard heparin, LMW heparins are indirect antithrombins and utilize antithrombin III to mediate inhibition of thrombin and FXa. As LMW heparins have more p ...
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... American College of Rheumatology Subcommittee on Rheumatoid Arthritis Guidelines hospitalizations per year (3,4). Disability from RA causes major economic loss and can have a profound impact on families. RA affects 1% of the adult population (2). This low prevalence means that the average physician ...
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... must guard against prescribing too many drugs, or preparations of little value. Drugs of unproven clinical value should be avoided, as well as potentially toxic agents if drugs equally effective but less dangerous are available. Risk-benefit and cost-benefit should be considered. Drugs may be prescr ...
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Acceptance and commitment therapy for depression following

... Depression following psychosis is common and can impact negatively on individuals’ quality of life. This study conducted post-hoc analyses on 14 participants with psychosis from a larger randomised controlled trial who presented with clinically important levels of depression at baseline. Eight of th ...
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... Background: The increasing incidence of cancer and the search for more effective therapies with minimal collateral effects have prompted studies to find alternative new treatments. Among these, photodynamic therapy (PDT) has been proposed as a very promising new modality in cancer treatment with the ...
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... natural distribution shunts because of numerous sebaceous follicles, which allow more of the drug to penetrate to subepidermal structures.8 There is a defective epidermal barrier in atopic dermatitis, and the penetration of topical corticosteroids is 2 to 10 times greater than that through healthy ...
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Antithrombotic Therapy in Children

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Reviewing the reality: why we need to change * Peter J. Lin Introduction
Reviewing the reality: why we need to change * Peter J. Lin Introduction

... half-life (4–6 h), and hence it will be depleted first, but others have longer half-lives (up to 72 h). Therefore, the full effect is not achieved for several days. Another complicating factor is that proteins C and S, which are also inhibited by warfarin, are endogenous anticoagulants that reduce th ...
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Psychedelic therapy

Psychedelic therapy refers to therapeutic practices involving the use of psychedelic drugs, particularly serotonergic psychedelics such as LSD, psilocybin, DMT, mescaline, and 2C-B, primarily to assist psychotherapy. As an alternative to synonyms such as ""hallucinogen"", ""entheogen"", ""psychotomimetic"" and other functionally constructed names, the use of the term psychedelic (""mind-manifesting"") emphasizes that those who use these drugs as part of a therapeutic practice believe these drugs can facilitate beneficial exploration of the psyche. In contrast to conventional psychiatric medication which is taken by the patient regularly or as-needed, in psychedelic therapy, patients remain in an extended psychotherapy session during the acute activity of the drug and spend the night at the facility. In the sessions with the drug, therapists are nondirective and support the patient in exploring their inner experience. Patients participate in psychotherapy before the drug psychotherapy sessions to prepare them and after the drug psychotherapy to help them integrate their experiences with the drug.According to one Canadian study conducted in the early years of the 1960s, the greatest interest to the psychiatrist was the fact that LSD allowed for the ""illusional perception ('reperception') of the patient's original family figures (e.g. father, mother, parent surrogates and helpers, older siblings, grandparents and the like)"", typically experienced as distortions of the psychiatrist's face, body or activity. In technical terms, this was called ""perceptualizing the transference"".
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