sodium valproate in childhood epilepsy
... The annual incidence of epilepsy is relatively small and few studies have reported incidence cases by the type of seizure of epilepsy syndrome(4). It has been suggested that 1/5th of recently diagnosed children and nearly ¾ of prevalent cases are reported to have experienced more than one type of se ...
... The annual incidence of epilepsy is relatively small and few studies have reported incidence cases by the type of seizure of epilepsy syndrome(4). It has been suggested that 1/5th of recently diagnosed children and nearly ¾ of prevalent cases are reported to have experienced more than one type of se ...
NEW ZEALAND DATA SHEET SERETIDE® Inhaler (with
... their asthma occurs, if they find that short-acting relief bronchodilator treatment becomes less effective or if they need more inhalations than usual. Paradoxical Bronchospasm As with other inhalation therapy paradoxical bronchospasm may occur with an immediate increase in wheezing after dosing. Th ...
... their asthma occurs, if they find that short-acting relief bronchodilator treatment becomes less effective or if they need more inhalations than usual. Paradoxical Bronchospasm As with other inhalation therapy paradoxical bronchospasm may occur with an immediate increase in wheezing after dosing. Th ...
The influence of causal information on judgments of treatment efficacy J e. Y
... only the terminal effect). As such, the generative power of the root cause is greater than that of the intermediate cause, and a treatment acting upon the root cause should be deemed more effective than one acting upon the intermediate cause. Note that category membership removal as we have describe ...
... only the terminal effect). As such, the generative power of the root cause is greater than that of the intermediate cause, and a treatment acting upon the root cause should be deemed more effective than one acting upon the intermediate cause. Note that category membership removal as we have describe ...
... for this kind of organophosphate intoxication. That cholinergic crisis may occur is indisputable, and it can be demonstrated experimentally,9 but it is not clear whether or how often it occurs in patients treated with the standard drugs now in use. Indeed, as crisis itself has become less frequent, ...
DOBUTamine
... in the Physicians’ Desk Reference (PDR). In managing overdosage, consider the possibility of multiple drug overdoses, interaction among drugs, and unusual drug kinetics in your patient. The initial actions to be taken in a dobutamine hydrochloride overdose are discontinuing administration, establish ...
... in the Physicians’ Desk Reference (PDR). In managing overdosage, consider the possibility of multiple drug overdoses, interaction among drugs, and unusual drug kinetics in your patient. The initial actions to be taken in a dobutamine hydrochloride overdose are discontinuing administration, establish ...
Antiplatelet Drugs - OSU Center for Continuing Medical Education
... drugs such as dipyridamole and cilostazol have not been as extensively investigated. There are several newer investigational drugs such as cangrelor and ticagrelor, but whether they confer significant additional benefits remains to be established. Management of patients who are receiving antiplatele ...
... drugs such as dipyridamole and cilostazol have not been as extensively investigated. There are several newer investigational drugs such as cangrelor and ticagrelor, but whether they confer significant additional benefits remains to be established. Management of patients who are receiving antiplatele ...
Identification and control of HIV drug therapy using fuzzy systems
... Because of the unavailability of real data, the input-output data or the couples (X @ , Y@ ) needed to determine the fuzzy system parameters are generated using a semi-implicit finite difference method introduced in [14]. The constructed fuzzy system can be used as an inverse fuzzy controller (figur ...
... Because of the unavailability of real data, the input-output data or the couples (X @ , Y@ ) needed to determine the fuzzy system parameters are generated using a semi-implicit finite difference method introduced in [14]. The constructed fuzzy system can be used as an inverse fuzzy controller (figur ...
Adult Mental Health
... Jumping to conclusions or over-conservatism? Reasoning bias and belief conviction in OCD. ................................................................................................... 24 "Stopping" criteria in compulsive checking: An investigation into the factors that mediate the termination ...
... Jumping to conclusions or over-conservatism? Reasoning bias and belief conviction in OCD. ................................................................................................... 24 "Stopping" criteria in compulsive checking: An investigation into the factors that mediate the termination ...
Including information on the therapeutic window in bioequivalence
... is 80–125%. At the end of the twentieth century, average bioequivalence as proposed by Schuirmann was questioned because it only focusses on whether the average exposure of the study population is equivalent (Anderson and Hauck, 1990, Scheiner 1992). In the typical situation where drugs are on the m ...
... is 80–125%. At the end of the twentieth century, average bioequivalence as proposed by Schuirmann was questioned because it only focusses on whether the average exposure of the study population is equivalent (Anderson and Hauck, 1990, Scheiner 1992). In the typical situation where drugs are on the m ...
BayeraspirinHCP.com
... The Clinical Trials Continue Aspirin has been studied alone and in combination with a wide range of drugs and for numerous conditions.5 There are many clinical trials currently underway, including, but not limited to 1-3: A Study of Cardiovascular Events in Diabetes (ASCEND) n Aspirin in Reducing Ev ...
... The Clinical Trials Continue Aspirin has been studied alone and in combination with a wide range of drugs and for numerous conditions.5 There are many clinical trials currently underway, including, but not limited to 1-3: A Study of Cardiovascular Events in Diabetes (ASCEND) n Aspirin in Reducing Ev ...
Psychotropic Medication and Interaction with Alcohol
... Sussex Partnership NHS Trust clinical policy Alcohol, Harmful Substance and Illegal Drug Use by Service Users and Visitors in Inpatient Services and Trust Premises states that ‘any situation where a service user is found to be misusing substances (includes alcohol in excess), whilst in hospital must ...
... Sussex Partnership NHS Trust clinical policy Alcohol, Harmful Substance and Illegal Drug Use by Service Users and Visitors in Inpatient Services and Trust Premises states that ‘any situation where a service user is found to be misusing substances (includes alcohol in excess), whilst in hospital must ...
Efficacy of atypical v. typical antipsychotics in the treatment of early
... independently reviewed all the identified abstracts from the electronic search, selected the studies included and extracted the data. Any conflicts were discussed with a third reviewer (P.P.). References of the identified studies and published reviews on pharmacological management of first-episode p ...
... independently reviewed all the identified abstracts from the electronic search, selected the studies included and extracted the data. Any conflicts were discussed with a third reviewer (P.P.). References of the identified studies and published reviews on pharmacological management of first-episode p ...
Preventing Occupational Exposure to Antineoplastic and Other
... evaluation of every marketed drug. Instead, compliance requires practice-specific assessments for drugs used at any one time by a facility. However, hazardous drug evaluation is a continual process. Local hazard communication programs should provide for assessment of new drugs as they enter the mark ...
... evaluation of every marketed drug. Instead, compliance requires practice-specific assessments for drugs used at any one time by a facility. However, hazardous drug evaluation is a continual process. Local hazard communication programs should provide for assessment of new drugs as they enter the mark ...
Average, population and individual bioequivalence
... drug, they are assumed to be therapeutic equivalents and therefore to have the same efficacy and safety profile.2 It is also assumed that original efficacy and safety have been evaluated and established during the approval process for the reference drug. In such a situation, the average of bioavaila ...
... drug, they are assumed to be therapeutic equivalents and therefore to have the same efficacy and safety profile.2 It is also assumed that original efficacy and safety have been evaluated and established during the approval process for the reference drug. In such a situation, the average of bioavaila ...
Implications of Recent Clinical Trials for the National Cholesterol
... option, ie, a reasonable clinical strategy, on the basis of available clinical trial evidence. This therapeutic option extends also to patients at very high risk who have a baseline LDL-C ⬍100 mg/dL. Moreover, when a high-risk patient has high triglycerides or low high-density lipoprotein cholestero ...
... option, ie, a reasonable clinical strategy, on the basis of available clinical trial evidence. This therapeutic option extends also to patients at very high risk who have a baseline LDL-C ⬍100 mg/dL. Moreover, when a high-risk patient has high triglycerides or low high-density lipoprotein cholestero ...
Update on Azole Antifungals
... voriconazole can cause hepatotoxicity, mainly manifested by elevation of AST/ALT, which, on rare occasion, can be serious or lethal.[91] Both visual changes and hepatotoxicity have been associated with high voriconazole blood levels.[9] Visual and, rarely, auditory hallucinations can occur in less t ...
... voriconazole can cause hepatotoxicity, mainly manifested by elevation of AST/ALT, which, on rare occasion, can be serious or lethal.[91] Both visual changes and hepatotoxicity have been associated with high voriconazole blood levels.[9] Visual and, rarely, auditory hallucinations can occur in less t ...
PRODUCT MONOGRAPH CLARUS Isotretinoin 10 mg and 40 mg
... Clinical studies of isotretinoin did not include sufficient numbers of subjects aged 65 years and over to determine whether they respond differently from younger subjects. Although reported clinical experience has not identified differences in responses between elderly and younger patients, effects ...
... Clinical studies of isotretinoin did not include sufficient numbers of subjects aged 65 years and over to determine whether they respond differently from younger subjects. Although reported clinical experience has not identified differences in responses between elderly and younger patients, effects ...
(Avinza): prescribing information
... Morphine concentrations are not predictive of analgesic response, especially in patients previously treated with opioids. The minimum effective concentration varies widely and is influenced by a variety of factors, including the extent of previous opioid use, age, and general medical condition. Effe ...
... Morphine concentrations are not predictive of analgesic response, especially in patients previously treated with opioids. The minimum effective concentration varies widely and is influenced by a variety of factors, including the extent of previous opioid use, age, and general medical condition. Effe ...
Barriers to Antiretroviral Therapy Adherence
... issues, stigma, adverse side effects and cost were the most commonly found adherence barriers. Scheduling issues and the adverse side effects seem to be universal barriers for patients all over the world. Stigma was more prominent barrier in articles conducted in African countries and cost was found ...
... issues, stigma, adverse side effects and cost were the most commonly found adherence barriers. Scheduling issues and the adverse side effects seem to be universal barriers for patients all over the world. Stigma was more prominent barrier in articles conducted in African countries and cost was found ...
Management of Opioid Therapy for Chronic pain BD)
... paucity of data regarding long-term opioid efficacy. In the absence of these data, providers must rely on whatever information is available to inform their clinical judgment, balancing the benefit and harm, in order to make decisions regarding their individual patient. Clinicians need to recognize t ...
... paucity of data regarding long-term opioid efficacy. In the absence of these data, providers must rely on whatever information is available to inform their clinical judgment, balancing the benefit and harm, in order to make decisions regarding their individual patient. Clinicians need to recognize t ...
BACTERIOPHAGE THERAPY William C. Summers
... natural conditions. Phage treatment was by the oral route, which minimized the possibility that other material in the phage lysate, e.g., bacterial debris, acted as an active immunogen (as it might, had it been injected parenterally). In these experiments, phage offered a high degree of protection. ...
... natural conditions. Phage treatment was by the oral route, which minimized the possibility that other material in the phage lysate, e.g., bacterial debris, acted as an active immunogen (as it might, had it been injected parenterally). In these experiments, phage offered a high degree of protection. ...
Ribavirin (Rebetol, Copegus)
... consideration as the anemia could trigger a lack an insufficient oxygen in a portion of the heart muscle (ischemia). Strokes also have been reported during combination therapy with alpha interferon and ribavirin. In addition, ribavirin is eliminated (excreted) in the urine. The drug should not be us ...
... consideration as the anemia could trigger a lack an insufficient oxygen in a portion of the heart muscle (ischemia). Strokes also have been reported during combination therapy with alpha interferon and ribavirin. In addition, ribavirin is eliminated (excreted) in the urine. The drug should not be us ...
A review of the use of combination therapies for the treatment of
... acne is most likely due to their effect on the microcomedo, the precursor stage of both inflammatory and noninflammatory lesions. The recently described effect in down-regulation of Toll-like receptor expression is a new finding that supports the potential for benefit in inflammatory acne.10 Benzoyl ...
... acne is most likely due to their effect on the microcomedo, the precursor stage of both inflammatory and noninflammatory lesions. The recently described effect in down-regulation of Toll-like receptor expression is a new finding that supports the potential for benefit in inflammatory acne.10 Benzoyl ...
Enhancing adherence in clinical research
... health matters, as presented in Table 2. Phase I studies, the first research on human beings, are concerned with establishing whether agents are safe for use with humans. For approximately 70% of investigational agents that reach this phase of testing, basic safety usually is demonstrated. Phase II ...
... health matters, as presented in Table 2. Phase I studies, the first research on human beings, are concerned with establishing whether agents are safe for use with humans. For approximately 70% of investigational agents that reach this phase of testing, basic safety usually is demonstrated. Phase II ...
Online Supplement Management of Atrial Fibrillation: Complete
... Recommendation 4 – ASA for patients with no risks besides CAD/arterial vascular disease (2016) . 34 Recommendation 5 – OAC therapy for patients ≥ 65 years or CHADS2 ≥ 1 (2016) ............................ 34 For patients with AF and recent elective PCI, the selection of antithrombotic therapy should ...
... Recommendation 4 – ASA for patients with no risks besides CAD/arterial vascular disease (2016) . 34 Recommendation 5 – OAC therapy for patients ≥ 65 years or CHADS2 ≥ 1 (2016) ............................ 34 For patients with AF and recent elective PCI, the selection of antithrombotic therapy should ...