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Chapter 9 the need for energy
Chapter 9 the need for energy

Anti-5HT1D Receptor antibody
Anti-5HT1D Receptor antibody

... WB: 1/1000. Detects a band of approximately 42kDa kDa (predicted molecular weight: 45.2 kDa). ELISA: positive result against immunising peptide. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. ...
AP Biology
AP Biology

Chapter 5 Chemical Messengers
Chapter 5 Chemical Messengers

... o Neurohormone is a special class of hormone that is produced by neurons and secreted into the blood. Examples: Antidiuretic hormone (ADH), oxytocin • Chemical Classification of Messengers by Chemical Properties (Table 5.2) o Solubility properties o Chemical class o A lipophobic ligand is water solu ...
Effector mechanisms of immunity
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... with distinct Fc regions, ready to perform various effector functions, • Affinity maturation – prolonged antigen stimulation leads the production of antibodies with higher and higher affinities for the antigen. This results in increased ability of antibodies to neutralize or eliminate microbes, • Av ...
DOC - ADAM Interactive Anatomy
DOC - ADAM Interactive Anatomy

... The presence of what ion inside the cell causes the synaptic vesicles to fuse with the membrane? ________ ...
The Nervous System II: Synaptic Transmission
The Nervous System II: Synaptic Transmission

... The presence of what ion inside the cell causes the synaptic vesicles to fuse with the membrane? ________ ...
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... Alpha1A – contraction of smooth muscle – high density in prostate gland; also found on arteries and veins Alpha1B – most abundant type in heart (function??), may be involved with alpha 1A in cardiac growth and structure, may be more abundant on blood vessels as we get older; Alpha1C was discovered a ...
Document
Document

Cell Communication
Cell Communication

- TCYonline.com
- TCYonline.com

... enzyme limits the rate of all the other Binds to a site different from the substrate binding enzymes in the reaction cascade. site. Isoforms Substrates and false substrates Most enzymes have more than one isoform. Drugs can act as substrates, substituting for The development of drugs whi ...
FEATURES PN 1 Nucleotide release and airway epithelial physiology
FEATURES PN 1 Nucleotide release and airway epithelial physiology

... extracellular ATP has been detected in the majority of non-excitatory tissues, including most epithelia, endothelia, smooth muscle, fibroblasts, astrocytes, and blood cells. The significance of nucleotides as extracellular signalling molecules is emphasised by the ubiquitous distribution of several ...
03 Endocrine and Cell Communication Hormonal Communication PPT
03 Endocrine and Cell Communication Hormonal Communication PPT

... Pathway for Lipid-Soluble Hormones • The response to a lipid-soluble hormone is usually a change in gene expression • Steroids, thyroid hormones, and the hormonal form of vitamin D enter target cells and bind to protein receptors in the cytoplasm or nucleus • Protein-receptor complexes then act as ...
slides#10 - DENTISTRY 2012
slides#10 - DENTISTRY 2012

... Ag-Ab → mast cell degranulation - Non-specific (non-antigen-mediated) Drugs (antibiotics, anticancerous agents, compound 48/80…etc), dyes, venoms, mechanical or thermal stress ...
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... i. Gap junctions – cells are connected by tunnels formed by connexons 1. Allows ions and small water soluble chemicals to pass between cells 2. Examples: cardiac and smooth muscle ii. Cell to cell recognition – interaction of cell-surface molecules 1. Example: immune cells – recognize self vs. non-s ...
Cell Communication
Cell Communication

... i. Gap junctions – cells are connected by tunnels formed by connexons 1. Allows ions and small water soluble chemicals to pass between cells 2. Examples: cardiac and smooth muscle ii. Cell to cell recognition – interaction of cell-surface molecules 1. Example: immune cells – recognize self vs. non-s ...
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Concept 11.2 Reception: A signaling molecule binds to a receptor

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UNIVERSITY OF MALTA

... differences, inducibility and regulation. It is now routine at an early stage in drug discovery to determine the human CYP isoform(s) responsible for the major oxidative pathways in the metabolism of a new chemical entity (NCE). The pregnane X receptor (PXR) and the constitutive androstane receptor ...
lecture-2-hhd - WordPress.com
lecture-2-hhd - WordPress.com

... response in some cells (glucagon/epinephrine) In most receptor-ligand system, the ligand do not have any function except to bind to receptor Upon binding it changes the properties of receptor which then produce signals to the cell that a specific product is present Target cells often degrade or modi ...
TYPES OF RECEPTORS
TYPES OF RECEPTORS

3-Mrp-Phe-Cha-Cha-Arg-Lys-Pro-Asn-Asp-Lys - Sigma
3-Mrp-Phe-Cha-Cha-Arg-Lys-Pro-Asn-Asp-Lys - Sigma

... The PAR-2 receptor is expressed at high levels in colon, pancreas, small intestine, and kidney as well as endothelial, epithelial, and smooth muscle cells. It is involved in digestive exocrine functions, triggering amylase secretion and pancreatic duct epithelial cell ion channel activation. The PAR ...
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ATP Adenosine Triphosphate

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邵吉民_Signaling_and_diseases
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... To regulate the level and modifications of modification enzymes, messengers, signal transducers, transcription factors, effectors, etc ...
powerpoint
powerpoint

... – regulate many processes in all tissues - including release of other hormones – All secreted polypeptide hormones are synthesized with a signal sequence (which directs them to secretory granules) – Usually synthesized as inactive preprohormones ("pre-pro" ...
G protein-coupled receptor
G protein-coupled receptor

... Once activated, the effector protein produces a second messenger. -second messenger generates the cellular response to the original signal For example – one common effector protein is adenylyl cyclase which produces cAMP as a second messenger. ...
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Purinergic signalling



Purinergic signalling (or signaling: see American and British English differences) is a form of extracellular signalling mediated by purine nucleotides and nucleosides such as adenosine and ATP. It involves the activation of purinergic receptors in the cell and/or in nearby cells, thereby regulating cellular functions.The purinergic signalling complex of a cell is sometimes referred to as the “purinome”.
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