Expression and transcriptional activity of progesterone receptor A
... differentiation in the breast by modulation of milk protein synthesis [1]. In the human endometrium, progesterone directs glandular differentiation and glycogenesis, as well as stromal proliferation and development of predecidual cells [1]. These effects are mediated through the nuclear progesterone ...
... differentiation in the breast by modulation of milk protein synthesis [1]. In the human endometrium, progesterone directs glandular differentiation and glycogenesis, as well as stromal proliferation and development of predecidual cells [1]. These effects are mediated through the nuclear progesterone ...
7. Skeletal Muscle Physiology
... H-band = myosin only I-band = actin only A-band = all of the myosin ...
... H-band = myosin only I-band = actin only A-band = all of the myosin ...
Analysis of the Juxtamembrane Dileucine Motif in the Insulin Receptor
... of the b-subunit of the insulin receptor and kinase activation (1, 2). The second step in endocytosis, interaction of the ligand-receptor complexes with clathrin-coated pits, involves other structures in the intracellular domain (3, 4). Subsequently, insulin-receptor complexes are internalized into ...
... of the b-subunit of the insulin receptor and kinase activation (1, 2). The second step in endocytosis, interaction of the ligand-receptor complexes with clathrin-coated pits, involves other structures in the intracellular domain (3, 4). Subsequently, insulin-receptor complexes are internalized into ...
Vesicle formation and targeting is a multi
... • Fibroblasts of patients contain large inclusions (I-cells)… • Lysosomes lack normal complement of acid hydrolases… • All lysosomal enzymes secreted (secretion is the “default” fate for proteins in the ER-Golgi pathway)… • Lysosomal enzymes of “wild-type” (normal) cells are modified by phosphorylat ...
... • Fibroblasts of patients contain large inclusions (I-cells)… • Lysosomes lack normal complement of acid hydrolases… • All lysosomal enzymes secreted (secretion is the “default” fate for proteins in the ER-Golgi pathway)… • Lysosomal enzymes of “wild-type” (normal) cells are modified by phosphorylat ...
Ferrara et al, Nat Med 2003 - Kashyap Memorial Eye Hospital
... angiogenic factors bind to endothelial cells of nearby capillaries and ...
... angiogenic factors bind to endothelial cells of nearby capillaries and ...
Identification of Amino Acid Residues within GABAA Receptor
... b2 pGW1 X hoI /SacII vector, and a X hoI /PstI fragment encoding residues 153–224 of the b3 subunit was ligated into the (FL AG)b2 pGW1 X hoI /PstI vector to produce more refined chimeras. Further mutants were generated by site-directed mutagenesis using the oligonucleotides GGAGC TCGATC TTTGTCACGCC ...
... b2 pGW1 X hoI /SacII vector, and a X hoI /PstI fragment encoding residues 153–224 of the b3 subunit was ligated into the (FL AG)b2 pGW1 X hoI /PstI vector to produce more refined chimeras. Further mutants were generated by site-directed mutagenesis using the oligonucleotides GGAGC TCGATC TTTGTCACGCC ...
Protective effects of sphingosine-1
... after 90 min of reperfusion was 50.7 + 4.3 mmHg in untreated control hearts, but significantly lower in 500 nM FTY720-treated hearts (35.3 + 3.6 mmHg, P , 0.05 vs. control) (Figure 3B). Fifty nanomolar FTY720 did not attenuate the rise in LVEDP. Neither 50 nor 500 nM FTY720 showed a significant effe ...
... after 90 min of reperfusion was 50.7 + 4.3 mmHg in untreated control hearts, but significantly lower in 500 nM FTY720-treated hearts (35.3 + 3.6 mmHg, P , 0.05 vs. control) (Figure 3B). Fifty nanomolar FTY720 did not attenuate the rise in LVEDP. Neither 50 nor 500 nM FTY720 showed a significant effe ...
Plant hormone receptors: perception is everything
... organ level by using extracellular signaling molecules to communicate between cells. In animals, these extracellular signals usually take the form of small proteins or peptides, like insulin, or small organic-based hormone molecules, such as steroids or retinoids. In the case of plants, the organic ...
... organ level by using extracellular signaling molecules to communicate between cells. In animals, these extracellular signals usually take the form of small proteins or peptides, like insulin, or small organic-based hormone molecules, such as steroids or retinoids. In the case of plants, the organic ...
bio chapter 9
... monophosphate (AMP). • When a second phosphate group is added, more energy is required to force the two groups together. This molecule is called adenosine diphosphate, or ADP. ...
... monophosphate (AMP). • When a second phosphate group is added, more energy is required to force the two groups together. This molecule is called adenosine diphosphate, or ADP. ...
Selective Binding of the Scavenger Receptor C
... From the Glycobiology Institute, Department of Biochemistry, University of Oxford, Oxford OX1 3QU, United Kingdom ...
... From the Glycobiology Institute, Department of Biochemistry, University of Oxford, Oxford OX1 3QU, United Kingdom ...
BME 502: Handout on Synaptic Transmission #2
... concentration of neurotransmitter, T, in the synaptic cleft that is available to bind to the postsynaptic receptor, R, is dependent on the concentration of transmitter in the vesicles, the number of vesicles released, and the cleft geometry decline of neurotransmitter in the synaptic cleft is depend ...
... concentration of neurotransmitter, T, in the synaptic cleft that is available to bind to the postsynaptic receptor, R, is dependent on the concentration of transmitter in the vesicles, the number of vesicles released, and the cleft geometry decline of neurotransmitter in the synaptic cleft is depend ...
Making inroads into plant receptor kinase signalling pathways
... involved in physiological processes as diverse as selfpollen rejection, stem-cell maintenance and differentiation at the shoot meristem, the response to the brassinosteroid hormones and the innate response to bacterial pathogens. These new findings emphasize the remarkably high diversity of these si ...
... involved in physiological processes as diverse as selfpollen rejection, stem-cell maintenance and differentiation at the shoot meristem, the response to the brassinosteroid hormones and the innate response to bacterial pathogens. These new findings emphasize the remarkably high diversity of these si ...
Chemosensory organs as models of neuronal synapses
... sad‑1 mutants inappropriately accrete presynaptic components in the dendrites of both sensory neurons and motor neurons. These results suggest that the formation of polarized structures that promote receptiveending formation may also be under common control in these two cell types. Trafficking of re ...
... sad‑1 mutants inappropriately accrete presynaptic components in the dendrites of both sensory neurons and motor neurons. These results suggest that the formation of polarized structures that promote receptiveending formation may also be under common control in these two cell types. Trafficking of re ...
Consortium for Educational Communication
... Uncouplers Uncouplers are the compounds that increase the permeability of the inner mitochondrial membrane to protons. Protons enter the matrix at sites other than ATP synthase through holes made by these compounds. These compounds have no effect on electron transport chain, but they uncouple oxidat ...
... Uncouplers Uncouplers are the compounds that increase the permeability of the inner mitochondrial membrane to protons. Protons enter the matrix at sites other than ATP synthase through holes made by these compounds. These compounds have no effect on electron transport chain, but they uncouple oxidat ...
Oxidative Phosphorylation
... their reduction potentials. Recall from freshman chemistry that the reduction potential of redoxactive substances is easily measured with a volt meter and two separate chambers. Published reduction potentials for NADH and O2 show that electrons flow spontaneously from NADH to O2, with a combined red ...
... their reduction potentials. Recall from freshman chemistry that the reduction potential of redoxactive substances is easily measured with a volt meter and two separate chambers. Published reduction potentials for NADH and O2 show that electrons flow spontaneously from NADH to O2, with a combined red ...
Regulation of Lung Fibrosis: the impact of Smad3 post
... some patients fibrotic scar tissues persist several weeks to several months. While most patients recover without significant complications, some develop permanent nonfunctional scar tissues (fibrosis). The molecular mechanism underlying this discrepancy remains to be elucidated. Transforming growth ...
... some patients fibrotic scar tissues persist several weeks to several months. While most patients recover without significant complications, some develop permanent nonfunctional scar tissues (fibrosis). The molecular mechanism underlying this discrepancy remains to be elucidated. Transforming growth ...
G-protein-coupled receptor kinases
... GRKs are capable of phosphorylating certain receptors, they do not address the question of which endogenously expressed kinases actually mediate receptor phosphorylation and desensitization in a given cell. In earlier studies, heparin was used to inhibit GRK-mediated receptor phosphorylation and des ...
... GRKs are capable of phosphorylating certain receptors, they do not address the question of which endogenously expressed kinases actually mediate receptor phosphorylation and desensitization in a given cell. In earlier studies, heparin was used to inhibit GRK-mediated receptor phosphorylation and des ...
Angiotensin AT1-Receptors Depolarize Neonatal Spinal
... neurons perfused with N-ethylmaleimide. Of 29 interneurons sensitive to pertussis toxin or N-ethylmaleimide treatment, 9 cells displayed a decrease in membrane conductance that reversed at ⫺101.3 ⫾ 3.8 mV. In eight cells, membrane conductance increased and reversed at ⫺38.7 ⫾ 3.4 mV. In 12 cells, th ...
... neurons perfused with N-ethylmaleimide. Of 29 interneurons sensitive to pertussis toxin or N-ethylmaleimide treatment, 9 cells displayed a decrease in membrane conductance that reversed at ⫺101.3 ⫾ 3.8 mV. In eight cells, membrane conductance increased and reversed at ⫺38.7 ⫾ 3.4 mV. In 12 cells, th ...
Purinergic signalling
Purinergic signalling (or signaling: see American and British English differences) is a form of extracellular signalling mediated by purine nucleotides and nucleosides such as adenosine and ATP. It involves the activation of purinergic receptors in the cell and/or in nearby cells, thereby regulating cellular functions.The purinergic signalling complex of a cell is sometimes referred to as the “purinome”.