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... narrow over time. This process is called atherosclerosis. Plaque buildup can cause angina, a condition that causes chest pain or discomfort because the heart doesn’t get enough blood. This pain may also occur in the shoulders, arms, neck, jaw, or back. There are two forms of angina; stable or unstab ...
Immunology Lecture 1
Immunology Lecture 1

... However, there can be some bad effects as well, Example: During inflammation, there may be local discomfort and some damage to healthy tissues. ...
Julie Hutsick, 2011. Heart Failure.
Julie Hutsick, 2011. Heart Failure.

... Stages and Classes of Heart Failure Guidelines for diagnosing and treating Heart Failure have been developed by the American College of Cardiology and The American Heart Association There are four stages, A-D. Stages A and B are patients are risk for Heart Failure and stages C and D are patients wh ...
3-Autoimmune disorders - Light at the End of the
3-Autoimmune disorders - Light at the End of the

... The prevalence values depend on the genetic background of the studied populations, on the geographical area, sizes of the populations, and definitions of the parameters that are being considered as positive signs of a disease. Autoimmune diseases involve a multigenic predisposition. For example, an ...
Coronary Artery Disease
Coronary Artery Disease

... energy. As a result, CAD is often a silent disease which progresses undetected until the first effects of ischaemia appear. Symptoms of angina are the most common presentation of CAD. However, the underlying coronary atherosclerosis may also manifest suddenly as an acute heart attack or sudden cardi ...
Module 5a: Documenting Heart Failure
Module 5a: Documenting Heart Failure

... clinically significant, apart from the heart failure, or is not due to the heart failure (look for evidence of different etiology for the pleural effusion) ◦ If treatment of pleural effusion is not the same as that for heart failure (e.g., performing a thoracentesis—not routine tx for HF!), then the ...
Cardioanatomy - Sinoe Medical Association
Cardioanatomy - Sinoe Medical Association

... The walls of the four chambers of the heart are made of cardiac muscle called the myocardium. The chambers are lined with endocardium, simple squamous epithelium that also covers the valves of the heart and continues into the vessels as their lining (endothelium). The important physical characterist ...
Antibiotic Update for INPs
Antibiotic Update for INPs

... • Do not start antibiotics in the absence of clinical evidence of bacterial infection. • If there is evidence of a bacterial infection, use local guidelines to initiate prompt effective antibiotic treatment. • Document on the drug chart AND in the medical notes: ...
Immunopathology Type III: Immune Complex Disease
Immunopathology Type III: Immune Complex Disease

... mechanism for IgG-mediated immune complex disease to penicillin (almost always seen after a large depot injection) as well as true IgE-mediated penicillin allergy, which is a Type I immunopathology. Among other types of exogenous antigens, ►serum sickness-like symptoms can be seen in patients with v ...
Cardiology cases or, Murmurs for Dummies - OSCE-Aid
Cardiology cases or, Murmurs for Dummies - OSCE-Aid

... and there is no peripheral oedema nor stigmata of endocarditis. This is Aortic Stenosis, my differentials… • This patient has a diagnosis of Aortic Stenosis as evidenced by a slow rising pulse, an ejection systolic murmur heard loudest in the aortic area which radiates to the carotids. He/she has a ...
The Year in Cardiology 2013: heart failure
The Year in Cardiology 2013: heart failure

... unique factor in a multifactorial condition. Circulation 2012;126:2175 – 2176. ...
Is atherosclerosis an autoimmune disease? Open Access
Is atherosclerosis an autoimmune disease? Open Access

... plaques suggests that locally synthesized IL-1 protein may activate the synthesis of growth factors and other cytokines, leading to local inflammatory cascades [12]. Various studies have shown that Toll-like receptor (TLR) signaling is operative in the intima of atherosclerotic arteries, with a numb ...
hypersensitivity - immunology.unideb.hu
hypersensitivity - immunology.unideb.hu

... This is the so-called "speckled" pattern of staining which is more characteristic of the presence of autoantibodies to extractable nuclear antigens, particularly ribonucleoprotein. This pattern is not very specific, but may be seen with an entity called "mixed connective tissue disease" which is a m ...
heart pp - WTPS.org
heart pp - WTPS.org

... • Certain dental or medical procedures. • An infection or other medical condition.. • Catheters or needles.. ...
Factors affecting the Cardiac Cycle
Factors affecting the Cardiac Cycle

... a. Remove as much as possible of the Ringer’s solution from around the heart, using a medicine dropper. b. Flood the heart with fresh Ringer’s solution that has been cooled in an ice water bath to about 10°C (50°F). c. Record the heart movements, and determine the heart rate as before. d. Remove the ...
Antibiotics are powerful medications that should only be used for the
Antibiotics are powerful medications that should only be used for the

... that are recommended to prevent infections. We are also starting to promote appropriate antibiotic use with the support of national and international groups and resources. This brochure is part of an effort to help doctors, nursing staff, residents and families know when and how to use antibiotics. ...
Chapter 63 Lab Exercises
Chapter 63 Lab Exercises

... flood it with Ringer’s solution that has been heated on a hot plate to about 35°C (95°F). f. Record the heart movements, and determine the heart rate as before. g. Enter the results in Part B of the laboratory report. 7. Complete Part B of the laboratory report. 8. Test the effect of an ...
Heart Failure - North Alabama Animal Hospital
Heart Failure - North Alabama Animal Hospital

... CAUSE:  In healthy animals, as in healthy people, a normally functioning heart distributes blood continuously and evenly throughout the circulation to supply all the organs and tissues. However, some animals may develop heart disease, which compromises the circulation. The body has ways of reducing ...
Factors Affecting the Cardiac Cycle
Factors Affecting the Cardiac Cycle

... heart movements. The thread should be adjusted so that there is no slack in it, but at the same time, it should not be so taut that it pulls the heart out of its normal position (fig. 63.3). ...
Icd 10 preserved ejection fraction
Icd 10 preserved ejection fraction

... and in diagnosing and tracking heart failure. I50.9 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. This is the American ICD-10-CM version of I50.9. Heart Failure with Preserved Ejection Fraction and Heart Failure with Reduced Ejection Fract ...
Heart Failure - Royal Berkshire Hospital
Heart Failure - Royal Berkshire Hospital

... their body sends them. If breathlessness is only present on significant exertion, then the patient should be encouraged to take exercise regularly up to a point at which symptoms commence and then back off and exercise to a lower level. We now know that regular exercise improves the performance of t ...
diseases of the cardiovascular system
diseases of the cardiovascular system

...  Animals with small defects may have minimal or no signs  Larger defects may result in acute left-sided heart failure, usually by 8 weeks of age  A harsh holosystolic murmur ...
Heart Dysrhythmias Cheat Sheet Arrhythmias Description Causes
Heart Dysrhythmias Cheat Sheet Arrhythmias Description Causes

... missing complex. Normal P wave preceding each QRS complex. Pause not equal to multiple of the previous rhythm. Atrial and ventricular rhythms vary slightly. Irregular PR interval. ...
Thymus gland Bone marrow Secondary organs of immune system
Thymus gland Bone marrow Secondary organs of immune system

... of antibiotics for an infection… •as well as killing off the harmful bacteria causing the infection, •some of the good resident microbes will die, leaving an opportunity for others to grow. ...
Myocardial diseases
Myocardial diseases

... • Progressive cardiac dilatation and systolic (contractile) dysfunction, usually with concomitant hypertrophy • Also called Congestive cardiomyopathy • 25-35% familal/ genetic form • Acquired causes ...
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Rheumatic fever



Rheumatic fever, also known as acute rheumatic fever (ARF), is an inflammatory disease that can involve the heart, joints, skin, and brain. The disease typically develops two to four weeks after a throat infection. Signs and symptoms include fever, multiple painful joints, involuntary muscle movements, and a characteristic but uncommon non itchy rash known as erythema marginatum. The heart is involved in about half of cases. Permanent damage to the heart valves, known as rheumatic heart disease (RHD), usually only occurs after multiple attacks but may occasionally occur after a single case of ARF. The damaged valves may result in heart failure. The abnormal valves also increase the risk of the person developing atrial fibrillation and infection of the valves.Acute rheumatic fever may occur following an infection of the throat by the bacteria Streptococcus pyogenes. If it is untreated ARF occurs in up to three percent of people. The underlying mechanism is believed to involve the production of antibodies against a person's own tissues. Some people due to their genetics are more likely to get the disease when exposed to the bacteria than others. Other risk factors include malnutrition and poverty. Diagnosis of ARF is often based on the presence of signs and symptoms in combination with evidence of a recent streptococcal infection.Treating people who have strep throat with antibiotics, such as penicillin, decreases their risk of getting ARF. This often involves testing people with sore throats for the infection, which may not be available in the developing world. Other preventative measures include improved sanitation. In those with ARF and RHD prolonged periods of antibiotics are sometimes recommended. Gradual return to normal activities may occur following an attack. Once RHD develops, treatment is more difficult. Occasionally valve replacement surgery or repair is required. Otherwise complications are treated as per normal.Acute rheumatic fever occurs in about 325,000 children each year and about 18 million people currently have rheumatic heart disease. Those who get ARF are most often between the ages of 5 and 14, with 20% of first-time attacks occurring in adults. The disease is most common in the developing world and among indigenous peoples in the developed world. In 2013 it resulted in 275,000 deaths down from 374,000 deaths in 1990. Most deaths occur in the developing world where as many as 12.5% of people affected may die each year. Descriptions of the condition are believed to date back to at least the 5th century BCE in the writings of Hippocrates. The disease is so named because its symptoms are similar to those of some rheumatic disorders.
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