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Autoimmune Disorders: an Overview of Molecular and Cellular
Autoimmune Disorders: an Overview of Molecular and Cellular

... an increase in autoreactive antibodies or conventional T cells that leads to a flare-up of quiescent AD or an exacerbation of existing symptoms [14,15]. With respect to viruses, the onset of various AD has been variably associated with infection by HSV-1, Coxsackie virus, EpsteinBarr virus (EBV), hu ...
Document
Document

... T-cells, sensitised by prior infection with tubercle bacilli, NTM or by BCG vaccination are recruited to the skin site and release inflammatory cytokines. ...
Dendritic cells in autoimmune diseases Burkhard
Dendritic cells in autoimmune diseases Burkhard

... inflammation is provoked either by direct cytopathic effects or by immunopathological reactions against a persisting microbial agent. Infection-associated inflammation, for example, involves the release of cytokines and chemokines, which attract antiviral effector cells and lymphocytes of other spec ...
Heart Rate Variability Training - Biofeedback Federation of Europe
Heart Rate Variability Training - Biofeedback Federation of Europe

... rate predicts a greater risk for death after a heart attack and death from all causes in adults, especially sudden death. Studies have also shown that clinical depression lowers heart rate variability. What is the relationship between Heart Rate Variability and Biofeedback? Heart Rate Variability Bi ...
Heart sounds and heart murmurs sepataion
Heart sounds and heart murmurs sepataion

... length of each heart sound, the systolic and diastolic phases and the cardiac cycle. Time-frequency analysis and classification of the PCG signals have been studied by several authors.[7] Before any analysis, the PCG signal needs to be segmented into components (sounds or murmurs), and then the comp ...
Neurogenic atrial fibrillation
Neurogenic atrial fibrillation

... exertion nor emotional stress triggers the arrhythmia but a period of relaxation that follows may trigger it. Cough, nausea, rest, post-prandial states and alcohol are also precipitating factors.8 Vagally mediated AF rarely, if ever, progresses to permanent AF. A 24-hour ECG can confirm the role of ...
Ch26_Disorders of Cardiac Fxn - University of Perpetual Help
Ch26_Disorders of Cardiac Fxn - University of Perpetual Help

... Treatment depends on the cause. When infection is present, antibiotics specific for the causative agent usually are prescribed. Antiinflammatory drugs such as aspirin and nonsteroidal antiinflammatory agents (NSAIDs) may be given to minimize the inflammatory response and the accompanying undesirable eff ...
B-type natriuretic peptide in the management of heart failure
B-type natriuretic peptide in the management of heart failure

... as a quantitative marker of heart failure; its levels have good diagnostic accuracy and can be measured with a rapid and simple bed-side assay and are useful in the assessment of patients with acute dyspnoea. Factors, such as obesity and renal impairment, alter B-type natriuretic peptide levels. Mea ...
Ch08 - ISpatula
Ch08 - ISpatula

... When the electrical system malfunctions, the heart will beat too fast, too slow, at an irregular pace, or not at all, depending on the nature of the malfunction. Arrhythmia is most often defined as an irregular heartbeat at any speed. When the heart pumps too fast, defined as any rate greater than 1 ...
Caring for the Heart Failure Patient: Contemporary Nursing
Caring for the Heart Failure Patient: Contemporary Nursing

... A common problem in the management of people with heart failure is that most of them are uninformed of a condition that will remain with them for life31,32. ‘Heart failure’ is an unfortunate title that is not immediately understood and requires detailed explanation and reassurance. The term is often ...
Congestive Heart Failure Complicated with Chylothorax as the
Congestive Heart Failure Complicated with Chylothorax as the

... Although thyrotoxicosis is not rare, congestive heart failure as the manifestation of thyrotoxicosis is relatively uncommon. Coexistence of congestive heart failure and chylothorax is even rarer in hyperthyroid patients. A 37-year-old male patient had been well until 3 years ago when tachycardia and ...
Congestive heart failure: the case for decreased variability as a
Congestive heart failure: the case for decreased variability as a

... heart failure syndrome. With so much information about the various yet interrelated aspects of this complex syndrome, it would be useful to our conceptualization of this entity if much Decreased haemodynamic variability of this knowledge could be tied together under one unifying concept. This paper ...
review of the diagnosis and treatment of diastolic heart failure
review of the diagnosis and treatment of diastolic heart failure

... aortic stenosis, obesity and aging are also common causes (Satpathy, C, y Cols., ...
Using this template
Using this template

... quality standard • Covers assessment, diagnosis and management of chronic heart failure in adults • Describes markers of high-quality, cost-effective care that, when delivered collectively, should contribute to improving the effectiveness, safety and experience of care for people with chronic heart ...
VI. Case
VI. Case

... Essex RW, Yi Q, Charles PG, Allen PJ. Post-traumatic endophthalmitis. Ophthalmology. 2004 Nov;111(11):2015-22.Meredith TA. Posttraumatic endophthalmitis. Archives of ...
Valvular Stenosis - Grand Valley State University
Valvular Stenosis - Grand Valley State University

... Very short jet across a deformed, irregular calcified aortic valve Longer jet along smoother tapering symmetric rheumatic mitral valve ...
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Question 1

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MS Word - CL Davis Foundation
MS Word - CL Davis Foundation

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pdf 1.64 MB - Sarver Heart Center
pdf 1.64 MB - Sarver Heart Center

... Heart failure is present in more than 5 million people in the United States and increases by 550,000 each year. Fortunately, the vast majority of these individuals can be treated with medical therapy. Unfortunately, according to a study by the National Institute of Medicine, about 65,000 people per ...
Severe right heart failure in two patients with thyrotoxicosis
Severe right heart failure in two patients with thyrotoxicosis

... shows that Graves’ disease was documented in nine of the 16 cases and none had a toxic nodular goitre. This suggests an autoimmune mechanism for the association between thyrotoxicosis and PH or RHF. However, there is no firm evidence clarifying whether an autoimmune process and thyroid hormone exces ...
myocarditis - WordPress.com
myocarditis - WordPress.com

... Diagnosis: The diagnosis of myocarditis is usually presumptive. Because many cases are not clinically obvious, a high degree of suspicion is required. • Acute rheumatic fever: Myocarditis usually present Usually associated signs, with acute heart failure such as chorea, erythema and, in those with ...
Effect of the angiotensin-receptor
Effect of the angiotensin-receptor

... sub-classified according to whether patients had been last seen alive within 1 h or between 1 and 24 h. Apparent sudden deaths in patients who were last seen .24 h prior to death were separately categorized as presumed sudden death. Death due to MI was assigned for patients dying within 14 days of a ...
Aortic Root Abscess - Journal of Clinical and Preventive Cardiology
Aortic Root Abscess - Journal of Clinical and Preventive Cardiology

... provides useful anatomical definitions like the extent of annular involvement, extension of abscess to involve the sub-aortic curtain or upper inter-ventricular septum. All these are very important considerations for planning surgery in these patients (3). Once an aortic root abscess is detected, ur ...
PPT - American Academy of Pediatrics
PPT - American Academy of Pediatrics

... Initial Management of ABS Guidance for clinician regarding management of children with persistent symptoms: ̶ Antibiotic therapy – starting as soon as possible after the encounter ̶ Additional outpatient observation – for 3 days with plan to begin antibiotics if child does not improve or worsens at ...
1Basic Word Roots and Common Suffixes
1Basic Word Roots and Common Suffixes

... The Digestive Tract begins with the oral cavity. The teeth pulverize ingested food and soften it. The action of the tongue moves the partly digested food into the esophagus by swallowing. Then strong muscular contractions move the food to the stomach. In the stomach the food is further processed mec ...
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Rheumatic fever



Rheumatic fever, also known as acute rheumatic fever (ARF), is an inflammatory disease that can involve the heart, joints, skin, and brain. The disease typically develops two to four weeks after a throat infection. Signs and symptoms include fever, multiple painful joints, involuntary muscle movements, and a characteristic but uncommon non itchy rash known as erythema marginatum. The heart is involved in about half of cases. Permanent damage to the heart valves, known as rheumatic heart disease (RHD), usually only occurs after multiple attacks but may occasionally occur after a single case of ARF. The damaged valves may result in heart failure. The abnormal valves also increase the risk of the person developing atrial fibrillation and infection of the valves.Acute rheumatic fever may occur following an infection of the throat by the bacteria Streptococcus pyogenes. If it is untreated ARF occurs in up to three percent of people. The underlying mechanism is believed to involve the production of antibodies against a person's own tissues. Some people due to their genetics are more likely to get the disease when exposed to the bacteria than others. Other risk factors include malnutrition and poverty. Diagnosis of ARF is often based on the presence of signs and symptoms in combination with evidence of a recent streptococcal infection.Treating people who have strep throat with antibiotics, such as penicillin, decreases their risk of getting ARF. This often involves testing people with sore throats for the infection, which may not be available in the developing world. Other preventative measures include improved sanitation. In those with ARF and RHD prolonged periods of antibiotics are sometimes recommended. Gradual return to normal activities may occur following an attack. Once RHD develops, treatment is more difficult. Occasionally valve replacement surgery or repair is required. Otherwise complications are treated as per normal.Acute rheumatic fever occurs in about 325,000 children each year and about 18 million people currently have rheumatic heart disease. Those who get ARF are most often between the ages of 5 and 14, with 20% of first-time attacks occurring in adults. The disease is most common in the developing world and among indigenous peoples in the developed world. In 2013 it resulted in 275,000 deaths down from 374,000 deaths in 1990. Most deaths occur in the developing world where as many as 12.5% of people affected may die each year. Descriptions of the condition are believed to date back to at least the 5th century BCE in the writings of Hippocrates. The disease is so named because its symptoms are similar to those of some rheumatic disorders.
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