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IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... over 50 years during 2011 To 2014. The following variables were considered: Sex, Age, Medical History, Autopsy findings to macroscopic and histological evaluation of the Heart. The autopsies were performed according to standard techniques. In all subjects, the heart was dissected following standard ...
Reprint - Immune Tolerance Network
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... The breakdown of self-tolerance is probably influenced by the milieu in which a peptide is presented. For example, inflammation induced by activation of the innate immune system (e.g., after infections) can favor loss of tolerance.10 Such loss of tolerance is a likely explanation for the occasional ...
Classic Pediatric Rashes
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... ¾ Prodrome: malaise, coryza, low grade fever occur in some cases. ¾ Rapidly changing painful lesions. ¾ ThinThin-walled vesicles to ulcers to crusts. ¾ Rash in crops (usually 3). ...
Pharmacologic and Non-Pharmacologic Treatment of Chronic Atrial
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... The potential benefits of strict (resting heart rate <80 bpm, heart rate <110 bpm during moderate exercise) versus lenient (resting heart rate 110 bpm) rate control were addressed in the RACE II trial of patients with permanent AF29. The RACE II study shows that lenientrate control <110 bpm is not in ...
Autoimmune Disease is Causing Your Hashimoto Thyroiditis And How to Stop It!
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... and you do have a real problem, and yes, there is hope to feel better. My wish is that this book changes your life. Autoimmune is a process where your body is destroying its own tissue. There tends to be an unnecessary mystery around autoimmune disorders and like many named diagnoses, we are sometim ...
the role of open mitral valve repair or replacement for severe mitral
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... PATHOLOGY OF MITRAL VALVE STENOSIS The most common cause of mitral stenosis is rheumatic fever. Following the initial episode of rheumatic carditis, the inflamed leaflets adhere to each other on their atrial surfaces at the commissures, leaving a central orifice and causing mitral stenosis. In some ...
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- Wiley Online Library
- Wiley Online Library

... Effective management of HF depends on an accurate and rapid diagnosis. Currently, this requires assessment of symptoms and physical signs in combination with advanced and expensive imaging of cardiac structure and function. Symptom-based diagnostic challenges occur as co-morbidities of HF have simil ...
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DISORDER OF CARDIAC RHYTHM
DISORDER OF CARDIAC RHYTHM

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Persistent Atrial Fibrillation And Atrial Flutter Complicated By
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34066-Review - F6 Publishing Home
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... Received for publication 11 April 2005, revised 13 August 2005, accepted 29 August 2005 Available online 26 September 2005 ...
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... are a leading cause of death and disability. Yet some autoimmune diseases are rare, while others, such as Hashimoto’s disease, affect many people. ...
J Soler-Soler, J Sagristá-Sauleda, A Cabrera, J Sauleda-Parés, J Iglesias-Berengué,... Permanyer-Miralda and J Roca-Llop
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... We observed transient depression of sinus automaticity (fig. 1) requiring no treatment in the only infant who had received procainamide 1 hour before. When present, heart failure disappeared a few hours after termination of tachycardia. The only complication (severe hypotension with shock) was seen ...
Antibiotic Ointment
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... Smack DP, Harrington AC, Dunn C, et al. Infection and allergy incidence in ambulatory surgery patients using white petrolatum vs bacitracin ointment. A randomized controlled trial. JAMA 1996;276:972-7. The authors’ conclusion: “White petrolatum is a safe, effective wound care ointment for ambulatory ...
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... in their chest, or their heart pounding. Others describe it as feeling like a thud or movement in their chest. Some say they feel their palpitations in their neck or through their ear when they are lying down. Most people who get palpitations don’t have a serious heart condition, but palpitations ca ...
Renal Pathology- Transplantation
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... • C4d has been the cornerstone in the diagnosis of AMR for one decade, it has become more and more clear that some cases of AMR with DSAs which are otherwise similar, do not have detectable C4d in biopsy sample. These C4d negative cases showed peritubular capillaritis and/or increased endothelial ac ...
Prakash P Punjabi - EuroValve congress 2017
Prakash P Punjabi - EuroValve congress 2017

... (P = 0.02) after exclusion of patients with associated diseases contributing to symptoms (right panel). b Event rate in asymptomatic patients caused by flail leaflets. The Kaplan–Meier curve depicts the incidence of the combined end point of symptoms of heart failure, new atrial fibrillation, cardia ...
Mitral Valve Repair
Mitral Valve Repair

... effective antibiotic treatment of streptococcal (ie, strep) infections.4 Untreated strep infections lead to rheumatic fever in which antibodies produced by the body to fight the infection also attack heart valve leaflet tissue, most commonly the mitral valve. In developing countries, children often ...
Morphology of autoimmune hepatitis - pathologie
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... Classification of autoimmune hepatitis Autoimmune hepatitis is a chronic progressive inflammation of the liver, which if left untreated will ultimately result in progressive destruction of the organ. The exact aetiology has not been sufficiently clarified. There are two different types of autoimmune ...
Agglutination Reactions
Agglutination Reactions

... 1. Serial dilutions of serum from a patient suspected to be infected with a given bacterium in tubes. 2. Addition of bacteria to these tubes with constant concentration (same amount and concentration for all tubes). 3. If the person was infected with these bacteria, a visible agglutination will form ...
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Rheumatic fever



Rheumatic fever, also known as acute rheumatic fever (ARF), is an inflammatory disease that can involve the heart, joints, skin, and brain. The disease typically develops two to four weeks after a throat infection. Signs and symptoms include fever, multiple painful joints, involuntary muscle movements, and a characteristic but uncommon non itchy rash known as erythema marginatum. The heart is involved in about half of cases. Permanent damage to the heart valves, known as rheumatic heart disease (RHD), usually only occurs after multiple attacks but may occasionally occur after a single case of ARF. The damaged valves may result in heart failure. The abnormal valves also increase the risk of the person developing atrial fibrillation and infection of the valves.Acute rheumatic fever may occur following an infection of the throat by the bacteria Streptococcus pyogenes. If it is untreated ARF occurs in up to three percent of people. The underlying mechanism is believed to involve the production of antibodies against a person's own tissues. Some people due to their genetics are more likely to get the disease when exposed to the bacteria than others. Other risk factors include malnutrition and poverty. Diagnosis of ARF is often based on the presence of signs and symptoms in combination with evidence of a recent streptococcal infection.Treating people who have strep throat with antibiotics, such as penicillin, decreases their risk of getting ARF. This often involves testing people with sore throats for the infection, which may not be available in the developing world. Other preventative measures include improved sanitation. In those with ARF and RHD prolonged periods of antibiotics are sometimes recommended. Gradual return to normal activities may occur following an attack. Once RHD develops, treatment is more difficult. Occasionally valve replacement surgery or repair is required. Otherwise complications are treated as per normal.Acute rheumatic fever occurs in about 325,000 children each year and about 18 million people currently have rheumatic heart disease. Those who get ARF are most often between the ages of 5 and 14, with 20% of first-time attacks occurring in adults. The disease is most common in the developing world and among indigenous peoples in the developed world. In 2013 it resulted in 275,000 deaths down from 374,000 deaths in 1990. Most deaths occur in the developing world where as many as 12.5% of people affected may die each year. Descriptions of the condition are believed to date back to at least the 5th century BCE in the writings of Hippocrates. The disease is so named because its symptoms are similar to those of some rheumatic disorders.
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