Name: page1 of 7 pages MOLECULAR BIOLOGY BIO372S January
... 11. Which of the following isotopes would be the most appropriate for the end-labeling of a DNA strand with a radioactive phosphate via polynucleotide kinase? A. α-32P B. 35S C. β -32P D. γ -32P E. 14C ...
... 11. Which of the following isotopes would be the most appropriate for the end-labeling of a DNA strand with a radioactive phosphate via polynucleotide kinase? A. α-32P B. 35S C. β -32P D. γ -32P E. 14C ...
Mutation, Repair, and Recombination
... Answer: a. and b. Mutant 1: most likely a deletion. It could be caused by radiation. Mutant 2: because proflavin causes either additions or deletions of bases and because spontaneous mutation can result in additions or deletions, the most probable cause was a frameshift mutation by an intercalating ...
... Answer: a. and b. Mutant 1: most likely a deletion. It could be caused by radiation. Mutant 2: because proflavin causes either additions or deletions of bases and because spontaneous mutation can result in additions or deletions, the most probable cause was a frameshift mutation by an intercalating ...
genomic diversity and differentiation
... • coalescent theory explains why recently-diverged populations may not yet have synapomorphies despite already being on different evolutionary paths ...
... • coalescent theory explains why recently-diverged populations may not yet have synapomorphies despite already being on different evolutionary paths ...
Finding the Lost Treasure of NGS Data
... Identification using RNAseq Data • Traditionally, somatic mutations are detected using Sanger sequencing or RT-PCR by comparing paired tumor and normal samples. One obvious limitation of such methods is that we have to limit our search to a certain genomic region of interest. • With the maturity of ...
... Identification using RNAseq Data • Traditionally, somatic mutations are detected using Sanger sequencing or RT-PCR by comparing paired tumor and normal samples. One obvious limitation of such methods is that we have to limit our search to a certain genomic region of interest. • With the maturity of ...
No Slide Title
... 2.Cause an excess of high-frequency derived (new) alleles. 3.Create long-range associations with neighboring loci— the “long-range haplotype,” That is, a selective sweep will lead to creation of linkage disequilibrium over large swaths of DNA around the positively selected variant. 4.The positive se ...
... 2.Cause an excess of high-frequency derived (new) alleles. 3.Create long-range associations with neighboring loci— the “long-range haplotype,” That is, a selective sweep will lead to creation of linkage disequilibrium over large swaths of DNA around the positively selected variant. 4.The positive se ...
No Slide Title
... These are 1 to 5 kb in length consisting of repeats 15 to 100 nucleotides in length and are identified by Southern analysis. 2. Microsatellite DNA ...
... These are 1 to 5 kb in length consisting of repeats 15 to 100 nucleotides in length and are identified by Southern analysis. 2. Microsatellite DNA ...
Final Exam Study Guide
... Microarray experiments (how they are done and what they mean) Yeast two hybrid experiments (how they are done and what they mean) The different types of transposable elements (IS, Composite Tn, Simple Tn, Retroposons, DNA TEs such as Ac/Ds and the P element, LINES and SINES) and how they move The tw ...
... Microarray experiments (how they are done and what they mean) Yeast two hybrid experiments (how they are done and what they mean) The different types of transposable elements (IS, Composite Tn, Simple Tn, Retroposons, DNA TEs such as Ac/Ds and the P element, LINES and SINES) and how they move The tw ...
Eukaryotic Genomes
... over different chromosomes • to coordinate their gene expression, each gene is regulated by the same control elements & these control elements are activated by the same ...
... over different chromosomes • to coordinate their gene expression, each gene is regulated by the same control elements & these control elements are activated by the same ...
Genetics Exam 5
... A. exhibit altered mitosis B. are unable to asexually reproduce C. exhibit altered growth D. have low fertility E. are not viable _____ Pollen from one species germinates on the stigma of another related species and sexually fertilizes the ovule. Most of the resulting plants are sterile but some of ...
... A. exhibit altered mitosis B. are unable to asexually reproduce C. exhibit altered growth D. have low fertility E. are not viable _____ Pollen from one species germinates on the stigma of another related species and sexually fertilizes the ovule. Most of the resulting plants are sterile but some of ...
Genetics Pre/Post Test
... 29. An organism's physical appearance is its _____. 30. An organism's genotype is its 31. What does co-dominance mean in genetics? a. Both alleles are dominant. b. Both alleles are recessive. c. The alleles are neither dominant nor recessive. d. Each allele is both dominant and recessive. 32. A muta ...
... 29. An organism's physical appearance is its _____. 30. An organism's genotype is its 31. What does co-dominance mean in genetics? a. Both alleles are dominant. b. Both alleles are recessive. c. The alleles are neither dominant nor recessive. d. Each allele is both dominant and recessive. 32. A muta ...
Gap-junctional channel and hemichannel activity of two recently
... Gap-junction channels (GJCs) are formed by head-to-head association of two hemichannels (HCs, connexin hexamers). HCs and GJCs are permeable to ions and hydrophilic molecules of up to Mr ~1 kDa. Hearing impairment of genetic origin is common, and mutations of connexin 26 (Cx26) are its major cause. ...
... Gap-junction channels (GJCs) are formed by head-to-head association of two hemichannels (HCs, connexin hexamers). HCs and GJCs are permeable to ions and hydrophilic molecules of up to Mr ~1 kDa. Hearing impairment of genetic origin is common, and mutations of connexin 26 (Cx26) are its major cause. ...
DNA & RNA
... Process in which the genetic code of DNA is copied into a strand of RNA transcription Three sequential nucleotides in an mRNA molecule that code for a specific amino acid codon ...
... Process in which the genetic code of DNA is copied into a strand of RNA transcription Three sequential nucleotides in an mRNA molecule that code for a specific amino acid codon ...
1. DNA (genetic info is passed down through DNA and RNA) A
... If in ER then: polypeptide is released into ER, then to Golgi complex, vesicle to cell membrane, then exocytosis (may be given signals for exit/destination) Free ribosomes typically make products for the cell and are not exported ...
... If in ER then: polypeptide is released into ER, then to Golgi complex, vesicle to cell membrane, then exocytosis (may be given signals for exit/destination) Free ribosomes typically make products for the cell and are not exported ...
Biology~Chapter 12
... Genes found on the X chromosome are Xlinked genes Since the X chromosome is larger- there are more X-linked than Y- linked traits. NOTE: Since males have only 1 X- a male who carries the recessive allele will show the Xlinked trait. ...
... Genes found on the X chromosome are Xlinked genes Since the X chromosome is larger- there are more X-linked than Y- linked traits. NOTE: Since males have only 1 X- a male who carries the recessive allele will show the Xlinked trait. ...
Document
... • Mutagens increase the mutation rate by 10 to 1000 times • Ames test for chemical carcinogens ─ Tests for the ability of a chemical to increase the rate of mutation (i.e. Is X a mutagen?) ─ Selects for mutated bacteria ◦ Revertant: a cell that contains a mutation that corrects its original mutation ...
... • Mutagens increase the mutation rate by 10 to 1000 times • Ames test for chemical carcinogens ─ Tests for the ability of a chemical to increase the rate of mutation (i.e. Is X a mutagen?) ─ Selects for mutated bacteria ◦ Revertant: a cell that contains a mutation that corrects its original mutation ...
DNA Technology ppt 2014
... Treatment of a genetic disorder (like cystic fibrous) by correcting a defective gene that causes a deficiency of an enzyme. Nasal spray that carries normal enzyme gene. Body makes enzyme and patient breathes normally. ...
... Treatment of a genetic disorder (like cystic fibrous) by correcting a defective gene that causes a deficiency of an enzyme. Nasal spray that carries normal enzyme gene. Body makes enzyme and patient breathes normally. ...
3rd of 7 Review Packets
... If in ER then: polypeptide is released into ER, then to Golgi complex, vesicle to cell membrane, then exocytosis (may be given signals for exit/destination) Free ribosomes typically make products for the cell and are not exported ...
... If in ER then: polypeptide is released into ER, then to Golgi complex, vesicle to cell membrane, then exocytosis (may be given signals for exit/destination) Free ribosomes typically make products for the cell and are not exported ...
DNA - PBworks
... DNA Structure DNA consists of two molecules that are arranged into a ladder-like structure called a Double Helix. A molecule of DNA is made up of millions of ...
... DNA Structure DNA consists of two molecules that are arranged into a ladder-like structure called a Double Helix. A molecule of DNA is made up of millions of ...
Intro to Strawberry DNA Extraction Lab
... Where have you heard of genes before? What do genes have to do with DNA? Gene = Segments of DNA that control the production of protein ...
... Where have you heard of genes before? What do genes have to do with DNA? Gene = Segments of DNA that control the production of protein ...
WhatMakesCell-TipsForTeachers
... *All cells in an organism have the same genetic content, but the genes used (expressed) by the cell may be regulated in different ways. *Not all DNA codes for a protein; some segments of DNA are involved in regulatory or structural functions, and some have no as-yet known function. (HS-LS3-1) LS3.B: ...
... *All cells in an organism have the same genetic content, but the genes used (expressed) by the cell may be regulated in different ways. *Not all DNA codes for a protein; some segments of DNA are involved in regulatory or structural functions, and some have no as-yet known function. (HS-LS3-1) LS3.B: ...
That Come Close to the Bone - Max-Planck
... soon become the standard method used in routine human genetic diagnostics. The quality, speed and now lower costs of these new technologies have long since revolutionized research into biological issues. Equipped in this way, from the thousands of rare diseases, the Max Planck Researchers selected d ...
... soon become the standard method used in routine human genetic diagnostics. The quality, speed and now lower costs of these new technologies have long since revolutionized research into biological issues. Equipped in this way, from the thousands of rare diseases, the Max Planck Researchers selected d ...
Mutation
In biology, a mutation is a permanent change of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements. Mutations result from damage to DNA which is not repaired or to RNA genomes (typically caused by radiation or chemical mutagens), errors in the process of replication, or from the insertion or deletion of segments of DNA by mobile genetic elements. Mutations may or may not produce discernible changes in the observable characteristics (phenotype) of an organism. Mutations play a part in both normal and abnormal biological processes including: evolution, cancer, and the development of the immune system, including junctional diversity.Mutation can result in several different types of change in sequences. Mutations in genes can either have no effect, alter the product of a gene, or prevent the gene from functioning properly or completely. Mutations can also occur in nongenic regions. One study on genetic variations between different species of Drosophila suggests that, if a mutation changes a protein produced by a gene, the result is likely to be harmful, with an estimated 70 percent of amino acid polymorphisms that have damaging effects, and the remainder being either neutral or weakly beneficial. Due to the damaging effects that mutations can have on genes, organisms have mechanisms such as DNA repair to prevent or correct mutations by reverting the mutated sequence back to its original state.