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Weatherall Institute of Molecular Medicine (WIMM) University of
Weatherall Institute of Molecular Medicine (WIMM) University of

...  Initiated investigation of the superagonist antibody’s role in activating T-cells through Fcγ receptors  Made ample amounts of Fcγ receptor-His (constructs IIV) to be stored for use by the lab in the future  Produced ELISA, calcium assay, and TIRF data to be analyzed and used for informing futur ...
Read More - Division of Rheumatology
Read More - Division of Rheumatology

... This work on fluorescent microscopy also led to his independent identification of MHC class II molecules, with the recognition of what is now termed HLA-DR. He was the first to show HLA-DR is expressed on B cells and monocytes and early myeloid forms, but not resting T cells. His studies on the expr ...
PRINCIPLES OF PHARMACOLOGY FINAL EXAM
PRINCIPLES OF PHARMACOLOGY FINAL EXAM

... asthma. His pulse is rapid (100/min) and irregular, but his blood pressure is within normal limits (130/88 mm Hg). An electrocardiogram shows atrial flutter with a ventricular rate of 100 beats per minute. You prescribe warfarin for anticoagulation. After waiting a sufficient period of time for full ...
Common drugs Eruption
Common drugs Eruption

... production, which triggers the release of histamine and other mast-cell mediators 4-Idiosyncrasy: a response, not predictable from animal experiments, and its cause is often unknown, but genetic variation in metabolic pathways may be involved e.g. dapsone induced hemolysis due to glucose-6-phosphate ...
the neuromuscular junction disorders
the neuromuscular junction disorders

... according to response to 60–90 mg four times daily. Gastrointestinal side effects are common and can be extremely debilitating, although antimuscarinics such propantheline (15–30 mg three times daily) may provide some relief. Cholinergic crises caused by excessive doses of pyridostigmine are less co ...
STI Surveillance for Public Health
STI Surveillance for Public Health

Crimean-Congo hemorrhagic fever and pregnancy: Two
Crimean-Congo hemorrhagic fever and pregnancy: Two

... was not given to the two pregnant patients, but the patients recovered by only using the symptomatic treatment. Horizontal transmission of the disease from mother to the fetus was shown.7 In the study conducted on pregnant CCHF patients by Ergonul et al.8, three pregnant women were followed up, and ...
Production
Production

... • Infertility is “inability to conceive after one year of conjugal life without use of contraceptive methods.” • The term "primary infertility" is applied to “the couple who has never achieved a pregnancy.” • "secondary infertility" implies that “at least one previous conception has taken place.” ...
Document
Document

... •Treatment of acute gout is with anti-inflammatory drugs; prevention of more attacks is with colchicine and/or decreasing production of uric acid (allopurinol) or increasing uric acid excretion (probenecid) ...
Principles of Disease
Principles of Disease

PDF - the University Health Network
PDF - the University Health Network

... mitigate cardiotoxicity,” says Ms. Belford. “These cancer patients are dehydrated and experiencing fatigue. Beta blockers or other preventive drugs might make them feel worse with an unclear benefit,” she says. “We’re trying to get closer to get risk prediction models to treat those who will benefit ...
Oncology KOLS: AN IMPORTANT PIECE OF THE PUZZLE
Oncology KOLS: AN IMPORTANT PIECE OF THE PUZZLE

... “It’s important to establish a scientific collaboration,” he says. “We have to get the interest of the investigator before the process begins, even before Phase I or Phase II.” He says the company has three investigator-initiated clinical studies for Annexin and is discussing others. Annexin is a di ...
Overview Of Autoimmune Disease - American Proficiency Institute
Overview Of Autoimmune Disease - American Proficiency Institute

... response is a powerful system consisting of many components that work together to protect us from infectious diseases. A primary component of the immune system is WBCs (leukocytes), which attack the invading organism and destroy its ability to cause disease. Early in life, the body’s immune system m ...
IgG4-RD
IgG4-RD

... • In patients who are resistant to glucocorticoids or who are unable to have their dose reduced sufficiently, we use azathioprine (2 mg/kg/day) or mycophenolate mofetil (up to 2.5 g/day as tolerated) • B cell depletion therapy with rituximab is an effective treatment in many of the patients with dis ...
A case of Hashimoto`s encephalopathy presenting with seizures and
A case of Hashimoto`s encephalopathy presenting with seizures and

... With the aid of a detailed medical history and related auxiliary examination (such as CSF and MRI), it is easy to rule out these diseases. Regarding treatment for HE, the patient’s symptom improved significantly and rapidly after initiation of corticosteroid treatment, and eventually achieved a long ...
Treatment Of Rosacea With Intense Pulsed Light Photorejuvenation
Treatment Of Rosacea With Intense Pulsed Light Photorejuvenation

... around the nose, for more rapid resolution. Conclusions Intense Pulsed Light therapy is a safe and effective treatment for the signs and symptoms of rosacea. Longer-term follow-up and further studies will be ne cessary to elucidate the exact role of lasers in the treatment of rosacea, which is a chr ...
2009 ANZSNP program and abstracts
2009 ANZSNP program and abstracts

... least invasive and least costly manner. Direct analysis for mitochondrial DNA (mtDNA) rearrangements or "common" point mutations is worth attempting in patients suspected of classic conditions such as LHON, MELAS, MERRF, CPEO, Kearns-Sayre, Pearson and Leigh syndromes. However, in other patients, th ...
myasthenia-gravis(mg)
myasthenia-gravis(mg)

... (A) Administrative) (B) Progressive (C) Programmed ...
New Patient
New Patient

... not occur unless done in context of formal research ...
AIDS Update - Turner White
AIDS Update - Turner White

... analyzed. All six patients had low CD4 cell counts and various opportunistic infections; patients were all p24-antigen positive and had plasma virus loads ranging from 17,000 to more than 4 million copies/mL. Western blot analysis revealed that three HIPS patients had weak p24 antibody reactivity be ...
Determinant-specific Amino Acid Copolymers Induce Innate
Determinant-specific Amino Acid Copolymers Induce Innate

... [Compound] (M) PEPTIMMUNE CONFIDENTIAL ...
Clinical Slide Set. Multiple Sclerosis
Clinical Slide Set. Multiple Sclerosis

...  1st-dose bradycardia often occurs; don’t use with β-blockers or if patient has known heart block  Risk of retinal macular edema; eye exam required  Varicella vaccination needed before treatment, if not immune ...
Adverse Drug Reactions
Adverse Drug Reactions

... Can explain by known pharmacology or fit the allergy pattern of one of the suspected medicines ...
Genetic - Inserm
Genetic - Inserm

... diagnosed by means of a test is hemochromatosis. Although it is little known, this is the most common hereditary disease in France, affecting one in 300 people. It causes tiredness, joint pain and a gray complexion. It is due to excess iron in the body and leads to complications like cirrhosis, diab ...
Optimal Interventions in Animal Systems
Optimal Interventions in Animal Systems

... Optimizing replacement of dairy cows: modeling the effects of diseases. Prev Vet Med 61: 27-43. 4. Kristensen AR and Jorgensen E. 2000. Multi-level hierarchic Markov processes as a framework for herd management support. Ann Operations Res 94: 69-89. 5. Kristensen AR. 2003. A general software system ...
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Multiple sclerosis research

Treatments under investigation for multiple sclerosis may improve function, curtail attacks, or limit the progression of the underlying disease. Many treatments already in clinical trials involve drugs that are used in other diseases or medications that have not been designed specifically for multiple sclerosis. There are also trials involving the combination of drugs that are already in use for multiple sclerosis. Finally, there are also many basic investigations that try to understand better the disease and in the future may help to find new treatments.
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