Sympathomimetics
... Neurotransmitters are chemicals used to carry impulses from neurons to neurons or from neurons to tissue receptors. A. Catecholamines: SNS neurotransmitters 1. Norepinephrine 2. Epinephrine 3. Dopamine B. Norepinephrine is the primary neurotransmitter for SNS. C. Catecholamines are metabolized by tw ...
... Neurotransmitters are chemicals used to carry impulses from neurons to neurons or from neurons to tissue receptors. A. Catecholamines: SNS neurotransmitters 1. Norepinephrine 2. Epinephrine 3. Dopamine B. Norepinephrine is the primary neurotransmitter for SNS. C. Catecholamines are metabolized by tw ...
Sample of questions and their answers
... -Gemfebrozil:a-function as a ligand for peroxisome proliferator-activated receptor-alpha T b- inhibits lipoprotein lipaseF T c-lowers plasma triglycerides d-causes myopathyT Angina pectoris MCQ -The therapeutic action of propranolol in angina pectoris is believed to be primarily the result of:a-red ...
... -Gemfebrozil:a-function as a ligand for peroxisome proliferator-activated receptor-alpha T b- inhibits lipoprotein lipaseF T c-lowers plasma triglycerides d-causes myopathyT Angina pectoris MCQ -The therapeutic action of propranolol in angina pectoris is believed to be primarily the result of:a-red ...
6-作用于神经系统的药物
... tension and delusion. But Chlorpromazine is ineffective for depression (抑郁). The condition of some patients with depression will exacerbate after taking chlorpromazine. ...
... tension and delusion. But Chlorpromazine is ineffective for depression (抑郁). The condition of some patients with depression will exacerbate after taking chlorpromazine. ...
Hallucinogens - WordPress.com
... • Aldous Huxley publishes The Doors of Perception (1954) • Therapeutic research (1960s - 1970s) ...
... • Aldous Huxley publishes The Doors of Perception (1954) • Therapeutic research (1960s - 1970s) ...
Neurotransmitters
... • Aldous Huxley publishes The Doors of Perception (1954) • Therapeutic research (1960s - 1970s) ...
... • Aldous Huxley publishes The Doors of Perception (1954) • Therapeutic research (1960s - 1970s) ...
Pharmacology (translated questions from the Dutch master) 2012 1
... c. proton pomp inhibitors have an half-value life of 1.5h and are taken only once every 24h d. IMAO is chosen over SSRIs in a patient with depression (and who is treated with indirectly working sympathomimetic). e. An Addison crisis can only occur in patients that were treated with glucocorticoids d ...
... c. proton pomp inhibitors have an half-value life of 1.5h and are taken only once every 24h d. IMAO is chosen over SSRIs in a patient with depression (and who is treated with indirectly working sympathomimetic). e. An Addison crisis can only occur in patients that were treated with glucocorticoids d ...
Lecture 12, computers CORRECTED
... Modifications of known ligands that will enhance binding Prediction of activities of unknown compounds - virtual screening of libraries of compounds. Challenge: comparison of binding energies of structurally different ligands (called “scoring”). ...
... Modifications of known ligands that will enhance binding Prediction of activities of unknown compounds - virtual screening of libraries of compounds. Challenge: comparison of binding energies of structurally different ligands (called “scoring”). ...
L11- ANTIPLATELET DRUGS
... have slow onset of action (3 - 5 days). Pro-drugs, they have to be activated in the liver. bound to plasma proteins ...
... have slow onset of action (3 - 5 days). Pro-drugs, they have to be activated in the liver. bound to plasma proteins ...
Drugs Affecting the Gastrointestinal System and Nutrition
... through the GI tract and increases motility. Uses in delayed gastric emptying time and gastroesophageal reflux. ...
... through the GI tract and increases motility. Uses in delayed gastric emptying time and gastroesophageal reflux. ...
Pharmacodynamics
... receptor subtype in tissues with different proportions of spare receptors (A, B, C, and D) muscle contraction in vitro. Note all tissues show same max response to drug (intrinsic activity). The agonist shows highest potency (lowest EC50) at tissue with greatest proportion of spare receptors (A), a ...
... receptor subtype in tissues with different proportions of spare receptors (A, B, C, and D) muscle contraction in vitro. Note all tissues show same max response to drug (intrinsic activity). The agonist shows highest potency (lowest EC50) at tissue with greatest proportion of spare receptors (A), a ...
Naloxone as a Mu-Receptor Antagonist
... hydromorphone given to RC after surgery, are not selective for one type of MOR so both effects are seen with their use (2). As more drug binds the MOR, the analgesic and respiratory depressive effects become enhanced. In an overdose, respiratory depression overpowers the analgesia, causing a lifethr ...
... hydromorphone given to RC after surgery, are not selective for one type of MOR so both effects are seen with their use (2). As more drug binds the MOR, the analgesic and respiratory depressive effects become enhanced. In an overdose, respiratory depression overpowers the analgesia, causing a lifethr ...
Opioid Pharmacology
... Binding Affinity is measured by the equilibrium inhibition constant (Ki) for [H*] sufentanil (nM). The lower the value of (Ki), the Higher the binding affinity for the µ-receptor. ...
... Binding Affinity is measured by the equilibrium inhibition constant (Ki) for [H*] sufentanil (nM). The lower the value of (Ki), the Higher the binding affinity for the µ-receptor. ...
Year 2 Drug Table – ST
... hypertension to prevent K+ loss with diuretics. Motion sickness, normally prophylactically. Disorders of labyrinth, morning sickness, pre/post-operatively. ...
... hypertension to prevent K+ loss with diuretics. Motion sickness, normally prophylactically. Disorders of labyrinth, morning sickness, pre/post-operatively. ...
Psy 5260 – Summer I 2009 Week Seven Lecture Notes
... GABA analogue, increases GABA levels in brain Excellent pharmacokinetic profile: no binding to plasma proteins, not metabolized, excreted unchanged by kidneys, few pk drug interactions, half-life 5-7 hours Results of clinical studies suggest this agent is most effective as adjunctive med. In pts. re ...
... GABA analogue, increases GABA levels in brain Excellent pharmacokinetic profile: no binding to plasma proteins, not metabolized, excreted unchanged by kidneys, few pk drug interactions, half-life 5-7 hours Results of clinical studies suggest this agent is most effective as adjunctive med. In pts. re ...
Newer Antihypertensive Drugs
... Azilsartan Medoxomil at its maximal dose has superior efficacy to both Olmesartan and Valsartan at their maximal, approved doses without increasing adverse events. Azilsartan Medoxomil could provide higher rates of hypertension control within the ARB class. Hypertension 2011; 57: 413-4205 ...
... Azilsartan Medoxomil at its maximal dose has superior efficacy to both Olmesartan and Valsartan at their maximal, approved doses without increasing adverse events. Azilsartan Medoxomil could provide higher rates of hypertension control within the ARB class. Hypertension 2011; 57: 413-4205 ...
Therapy of Bipolar Disorder
... • Increased CNS monoamine neurotransmitter activity (particularly serotonin and dopamine) and reduced acetylcholine and GABA neurotransmission • Changes in neuronal function within the prefrontal cortex, visual association cortex and limbic circuitry ...
... • Increased CNS monoamine neurotransmitter activity (particularly serotonin and dopamine) and reduced acetylcholine and GABA neurotransmission • Changes in neuronal function within the prefrontal cortex, visual association cortex and limbic circuitry ...
Lester-BMB170C
... But Ca phosphate is insoluble near neutral pH. Therefore cells cannot have appreciable concentration of Ca2+; they typically maintain Ca2+ at < 10 –8 M. ...
... But Ca phosphate is insoluble near neutral pH. Therefore cells cannot have appreciable concentration of Ca2+; they typically maintain Ca2+ at < 10 –8 M. ...
6-rhinitis and cough2015-02-09 20:541.0 MB
... 5. Anti-arrhythmic actions !!! Promethazine, Antazoline by Na channel blocking action & local anesthetic effects ...
... 5. Anti-arrhythmic actions !!! Promethazine, Antazoline by Na channel blocking action & local anesthetic effects ...
L9-rhinitis and coug..
... 5. Anti-arrhythmic actions !!! Promethazine, Antazoline by Na channel blocking action & local anesthetic effects ...
... 5. Anti-arrhythmic actions !!! Promethazine, Antazoline by Na channel blocking action & local anesthetic effects ...
Simon Chiu and others(1981)11dec7
... Table I. Blockade of haloperidol (IIAL)-induced increase inspector I'Illspiropcridol binding by I -prolyl-l -lcucyl-glycinamide (I'I,(;). Male Sprague-I)awtey rats weighing 2(1(1 it) '50 g were randomly assigned to six groups and received various drug dosages or 21 days according to the living proto ...
... Table I. Blockade of haloperidol (IIAL)-induced increase inspector I'Illspiropcridol binding by I -prolyl-l -lcucyl-glycinamide (I'I,(;). Male Sprague-I)awtey rats weighing 2(1(1 it) '50 g were randomly assigned to six groups and received various drug dosages or 21 days according to the living proto ...
Hypoglossal Nerve Response to 5-HT3 Drugs Injected into the XII
... Adult male Sprague-Dawley rats (Charles River) weighing 320-390g were used. All procedures were approved by the Institutional Animal Care and Use Committee of the University of Pennsylvania. ...
... Adult male Sprague-Dawley rats (Charles River) weighing 320-390g were used. All procedures were approved by the Institutional Animal Care and Use Committee of the University of Pennsylvania. ...
CNS Drugs - Centegra Health System
... –– Loss Loss of of contact contact with with reality reality & & disorganized disorganized thoughts thoughts –– Probable Probable cause: cause: increased increased dopamine dopamine release release –– Tx. Tx. Aimed Aimed at at decreasing decreasing dopamine dopamine activity activity Two Two Chemica ...
... –– Loss Loss of of contact contact with with reality reality & & disorganized disorganized thoughts thoughts –– Probable Probable cause: cause: increased increased dopamine dopamine release release –– Tx. Tx. Aimed Aimed at at decreasing decreasing dopamine dopamine activity activity Two Two Chemica ...
MOTM SALVINORIN A MAGIC MINT
... It is the first compound discovered to act upon this receptor that isn’t an alkaloid; hallucinogens like this usually act on a serotonin receptor. It is also reportedly about the most potent natural psychoactive drug known. It seems to have similar potency to LSD, but acts in a different way, and If ...
... It is the first compound discovered to act upon this receptor that isn’t an alkaloid; hallucinogens like this usually act on a serotonin receptor. It is also reportedly about the most potent natural psychoactive drug known. It seems to have similar potency to LSD, but acts in a different way, and If ...
Baclofen: Interaction with GABA Receptor Leading to CNS Depression
... receptor agonists, such as baclofen, are a common treatment for spasticity because they are effective in reducing muscle tone and, thus, muscle spasticity. The treatment for long term pain management following such traumas often includes opioid analgesic medications as well. Providers prescribing bo ...
... receptor agonists, such as baclofen, are a common treatment for spasticity because they are effective in reducing muscle tone and, thus, muscle spasticity. The treatment for long term pain management following such traumas often includes opioid analgesic medications as well. Providers prescribing bo ...
5-HT3 antagonist
The 5-HT3 antagonists, informally known as ""setrons"", are a class of drugs that act as receptor antagonists at the 5-HT3 receptor, a subtype of serotonin receptor found in terminals of the vagus nerve and in certain areas of the brain.With the notable exception of alosetron and cilansetron, which are used in the treatment of irritable bowel syndrome, all 5-HT3 antagonists are antiemetics, used in the prevention and treatment of nausea and vomiting. They are particularly effective in controlling the nausea and vomiting produced by cancer chemotherapy and are considered the gold standard for this purpose.The 5-HT3 antagonists may be identified by the suffix –setron, and are classified under code A04AA of the WHO's Anatomical Therapeutic Chemical Classification System.