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Understanding By Design Unit Template Title of Unit Curriculum Area Developed By Mendelian Genetics and the study of Inheritance Biology Christy Atkinson Grade Level Time Frame 9th -10th 4 weeks Identify Desired Results (Stage 1) Big Idea: Content Standards 1. S:LS1:11:3.2 Recognize that new heritable characteristics can only result from new combinations of existing genes or from mutations of genes in organisms sex cells; and explain why other changes in an organism cannot be passed on. 2. S:LS3:11:3.5 Identify and describe ways genes may be changed and combined to create genetic variation within a species. 3. S:LS3:11:3.7 Explain the concepts of Mendelian Genetics. 4. S:LS3:11:3.8 Use pedigree charts and Punnett Squares to determine patterns of inheritance. 5. S:LS3:11:3.6 Explain that gene mutations and new combinations may have a variety of effects on the organism, including positive and negative ones, or none at all. 6. Other content standards appear on individual lessons as well; these are the unit standards overall. Enduring Understandings Essential Questions Overarching 1. All Life on Earth is connected through a shared genetic history. 2. Speciation of all organisms relies on the idea of variation. 3. The study of genetic history and diversity can be applied to all types of science, history, and cultural development. 1. 2. 3. 4. Topical Gregor Mendel made connections through his work with heredity that led to two fundamental laws in Biology and introduced a new study in science called genetics. The changes that occur during meiosis lead to the genetic variation among species. The study of genetics allows scientists’ to piece together and understand how life arose on earth. The study of DNA can lead into many new medical insights that can benefit mankind. Overarching 1. Without variation, what would the earth be like? 2. How does the study of inheritance effect human thought? 3. What ethic responsibilities do scientists have during their research of life? 4. What can the study of patterns of inheritance in all species tell us about the earth and the development of life? Knowledge Skills Students will know… Students will be able to… Topical 1. Why is meiosis an essential aspect of speciation? 2. How did Gregor Mendel’s work change modern science and thought on heredity? 3. What advantages does sexual reproduction give to a species? 4. How does the study of genes and variation provide evidence for evolution? 5. What insights can the study of human inheritance give to medicine? The vocabulary of Genetics: gene, allele, chromosome, meiosis, trait, dominant and recessive alleles, the law of segregation, the law of independent assortment, molecular genetics, punnett square, dihybrid and monohybrid crosses , genotype and phenotype, heterozygous, and homozygous, complete dominance, incomplete dominance, codominance, heredity, probability, Parental, filial (F1 F2) generations, true-breeding and pollination. Genetics is the study of how characteristics are transmitted from parents to offspring. Pedigree charts are used to track inheritance of traits among humans and other organisms. Punnet squares can be used to predict the outcome of genetic crosses of species. The fundamentals of modern genetics are based on Gregor Mendel’s work and conclusions into the two laws of segregation and independent assortment. All organisms are derived or formed from the same DNA or genetic material but are unique. An organism’s phenotype is the sum of all the genetic material from both parents and the interaction of that material as the zygote grows to an adult. Use a punnett (dihybrid and monohybrid) square to determine the probability of the distribution of a heritable trait of an organism among a population. Use meiosis to explain variation among species. Use the probability equation to determine generation numbers in plants based on Mendel’s experiments. Apply understanding of the relationship between a genotype and a phenotype using examples clearly stated with the vocabulary terms. Apply the process of scientific observation and method by providing examples in current day life to show that variation is based on the same genetic material that all life shares. Support Gregor Mendel’s contributions to the study of heredity using modern evidence of the current findings in molecular genetics sing such terms as homozygous and heterozygous etc. Apply understanding of dominant and recessive alleles as applied to inheritance using data collected from punnet squares and pedigree charts for traits in humans and other organisms. Analyze, interpret, create, and apply the scientific tools and process for public understanding to enhance and support their community and provide information and learning to others. Assessment Evidence (Stage 2) Performance Task Description: To create a brochure on about human blood types describing how they are used for blood donations in the medical or health field, and promote awareness in high school students and their families about the need for blood in their community. Students will also plan and carry out a blood drive for their high school. The tasks together will allow students to apply their understanding of genetics from the unit, including the tools and skills they have learned in a meaningful way that can also contribute to their community. Other Evidence (quizzes, test, prompts, observations, dialogues, student self-assessment, work samples.) A vocabulary quiz of the key terms of the unit. A punnet square activity used to assess understanding of the tool. Pedigree charts for participations grades will be given as well. A quiz with several punnet squares, and a scenario involving two parental types requiring a detailed explanation using the correct scientific terminology and understanding o the terminology describing how you would predict and explain the phenotypic traits of the offspring. An actual blood scenario for a specific blood disorder will be given for students to use the different tools they have learned in the unit to analyze, describe, and show understanding of the outcome and offspring, by predicating the outcome and comparing the “actual answer or phenotype of the offspring” to their results using the genetic tools learned in the unit. Reflections on the activities in several lessons are planned and several case studies for students to apply their understanding will be assigned as well. A unit exam will be given at the end of the unit. Performance task will be assigned and due within a week of the end of the unit and a blood drive as part of the performance task will be planned close to the unit though may not be contained within the same time frame. Karyotypes of specific genetic disorders will be given and students will put the Karyotypes together and explain the disease they have revealed using genetic terms, of medical analysis data, and research about chromosomal disease types. Students will present their Karyotypes in class and explain how they researched and discovered the disorder using the skills and tools they have learned. Learning Plan (Stage 3) Where are your students headed? Where have they been? How will you make sure the students know where they are going? How will you hook students at the beginning of the unit? What events will help students experience and explore the big idea and questions in the unit? How will you equip them with needed skills and knowledge? How will you cause students to reflect and rethink? How will you guide them in rehearsing, revising, and refining their work? How will you help students to exhibit and selfevaluate their growing skills, knowledge, and understanding throughout the unit? How will you tailor and otherwise personalize the learning plan to optimize the engagement and effectiveness of ALL students, without compromising the goals of the unit? How will you organize and sequence the learning activities to optimize the engagement and achievement of ALL students? Students will begin with an introduction to Gregor Mendel, the father of genetics, and follow this with specific tools to study inheritance, apply previous learned information about DNA structure and use of meiosis to describe variation and inheritance patterns of organisms. Lessons are numbered in order and will culminate with a performance task to complete the unit and combine understanding of the essential questions and understandings into one project. Students will watch a YouTube video that begins the discussion on genetic inheritance and variation and opens a lot of questions, possibilities, and information about genetics and its uses in the world. Students will gain learning through working with scientific tools to understand inheritance such as punnett squares, pedigree charts, Karyotypes, and case studies for genetic disease and use models such as fruit flies and dog pedigree analysis to apply these skills and understand their use. Students will be asked to reflect on the ethics of some information in certain lessons, document their learning as they do their performance task on human blood types, and us case studies to explain how genetics is used both ethically and advantageously in the medical world. Reflections and discussions on their work for many of the lessons. Students will have oral discussions to explain to their peers information in the form of jigsaw style learning and group learning, and will be given a rubric or asked to explain their contribution orally or in writing to the teacher as self evaluation. The performance task will have different roles for each student that will be chosen both on the basis on volunteer for the role and using the information through interactions with students to assign the roles best suited for each student. The lessons are organized and numbered to show how they would be taught in the unit, in some cases, it is possible a lesson would be added between these numbered lessons if the information is not successful in teaching understanding of the concepts to the students. Many of the lesson offer several learning styles and modifications are possible in many forms as well that would still be effective in achieving understanding of the overall goal and understandings of the unit. From: Wiggins, Grant and J. Mc Tighe. (1998). Understanding by Design, Association for Supervision and Curriculum Development ISBN # 0-87120-313-8 (ppk)