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Unit 4 Study Guide DNA Processes ENDURING UNDERSTANDINGS: Cellular processes maintain homeostasis. Proteins determine the structure and function of living things. Nucleic acids transfer genetic information from generation to generation. Objective 5: DNA PROCESSES Identify the structure & function of nucleic acids including their role in biodiversity. Essential Questions: 3) If there are only 4 nucleotide types in DNA, why are all living things so different? (DNA) SELF-ASSESSMENT CHART U = Unfamiliar (I can apply this target to a new situation.) F = Familiar (I can apply this target to a present or prior situation.) O = Objective Target (I can identify the target in a situation.) TARGET 1) 2) 3) 4) 5) 6) 7) Relate (Apply) the work of scientists to the discovery of DNA’s structure and function including Frederick Griffith Erwin Chargaff Rosalind Franklin James Watson & Francis Crick Show (Illustrate) how information for detailing (specifying) the characteristics (traits) of an organism is carried in DNA. Construct a model of a DNA molecule and analyze its structure in terms of its function including what makes up a nucleotide nitrogen base and matching (complementary) base pairing rule double helix shape (with two complementary strands) Using descriptions or diagrams of protein synthesis determine how the procedure (process) of transcription takes place, including the role of mRNA, and what is produced. determine how the process of translation takes place, including the role of tRNA, and what is produced. be able to use the Codon Chart to determine the matching (corresponding) amino acid Recognize the biomolecules nucleic acid as made of nucleotides proteins as structural molecules made up of amino acids enzymes as controllers (regulators) of activities. Investigate the significance of the nucleus to protein synthesis. ribosomes to protein synthesis. Identify and evaluate the significance of changes in DNA caused by frame-shift mutations. DNA Processes Study Guide – Student- (Revised June 25, 2008) U F O LESSONS DNA Structure PPT Notes DNA Structure PPT Notes The DNA Molecule ws The DNA Molecule ws DNA Model Lab DNA & Protein Synthesis PPT Notes Protein Synthesis Practice 1 &2 Protein Synthesis Person Lab Computer Simulated Protein Synthesis Practice The DNA Game DNA & Protein Synthesis PPT Notes DNA & Protein Synthesis PPT Notes Gene Mutation PPT Notes (printed 6/24/2017) p. 1 TARGET U F O LESSONS point mutations. 8) Recognize and apply biotechnology to the study of DNA Fingerprinting genetic variation in organisms including Paper Gene Splicing Cloning Discussion careers genetic engineering, including cloning electrophoresis (genetic fingerprinting) human genome project Underlined words in parentheses are terms normally used for the word or phrase before it. These are common formal language words you will see on activities and tests. Bolded words are vocabulary words found in the targets. Other important vocabulary will be studied in the unit lessons. SAMPLE QUESTIONS (These are samples of the type of questions which might be on the test. Questions may require students to use the basic content to make applications, analyze, synthesize and evaluate information. Tests contain unit content questions as well as general scientific processing questions.) DNA MUTATION REPAIR Figure 3 5' G T A _ _ _ A A 3' 3' C A T G C A T T 5' 1. This segment of DNA has undergone a mutation in which three nucleotides have been deleted. A repair enzyme would replace them with A. CGT. B. GCA. C. CTG. D. GTA. 2. A. B. C. D. Mutations within a DNA sequence are natural processes that produce genetic diversity. natural processes that always affect the phenotype. unnatural processes that always affect the phenotype. unnatural processes that are harmful to genetic diversity. 3. A. B. C. D. An inheritable mutation may occur if an organism has a change in its appendages. internal organs. DNA structure. ATP production rates. 4. A. B. C. D. Chromosomal mutations occurring in gametes of humans can affect the appearance of offspring because many traits are usually affected. only one trait is usually affected. these mutations usually speed up embryonic development. these mutations usually result in sex-linked traits. 5. A. B. C. D. The weakest bonds in a double-stranded molecule of deoxyribonucleic acid exist between the deoxyribose sugars. phosphate groups. nitrogenous bases. 5-carbon sugars. DNA Processes Study Guide – Student- (Revised June 25, 2008) (printed 6/24/2017) p. 2 GENETIC CODE CHART Figure 2 6. Look at figure 2. A strand of mRNA containing the repeating sequence AAGAAGAAGAAG could code for which of the following amino acid sequences? A. lys–arg–glu–lys B. ser–ser–glu–glu C. lys–arg–lys–arg D. lys–lys–lys–lys 7. A. B. C. D. Which of the following codons would signal a stop for the assembly of a protein? CUA ACG GAC UAG 8. A. B. C. D. One similarity between DNA and messenger RNA molecules is that they both contain the same sugar. genetic codes based on sequences of bases. a nitrogenous base known as uracil. double-stranded polymers. 9. A. B. C. D. The process of cloning involves making an identical copy of a cell’s cytoplasm. DNA. ribosomes. ATP. DNA Processes Study Guide – Student- (Revised June 25, 2008) (printed 6/24/2017) p. 3 DNA and RNA Figure 10 10. A. B. C. D. Look at Figure 10. Which mRNA sequence complements the above section of DNA? CUAGGA TCGAAG CTAGGC AGCUUC 11. A. B. C. D. Which of the following shows the three parts of an RNA nucleotide? ribose, phosphate group, thymine ribose, phosphate group, uracil deoxyribose, phosphate group, uracil deoxyribose, phosphate group, cytosine Comparing Fragments of DNA Table B 12. The shaded areas of Table B show the nucleotides that four fragments of DNA have in common. Which fragment is most different from the other three? A. Q B. R C. S D. T DNA Processes Study Guide – Student- (Revised June 25, 2008) (printed 6/24/2017) p. 4 NUCLEIC ACID MOLECULE 13. A. B. C. D. The boxed structure is a/an: DNA nucleotide RNA monomer amino acid codon 14. A. B. C. D. Which of these nucleic acids functions as a blueprint of the genetic code? tRNA mRNA rRNA DNA 15. A. B. C. D. Which molecule carries attached amino acids? tRNA mRNA rRNA DNA 16. A. B. C. D. Which of the statements best describes what happens during translation? mRNA is made by copying the DNA code. Proteins are produced at the ribosome. tRNA is made from mRNA’s code. DNA copies are produced. DNA Processes Study Guide – Student- (Revised June 25, 2008) (printed 6/24/2017) p. 5 Nucleotide Numbers in Plant Groups Figure 3 17. The chart in Figure 3 shows the range of numbers of nucleotides among species of different groups of plants. Which of these groups has the largest range of nucleotide numbers among its species? A. Bryophyta (mosses and liverworts) B. Lycopsida (club mosses) C. Gymnosperms (cedars and pines) D. Pteropsida (ferns) 18. A. B. C. D. Which of the following RNA types is/are involved in transcription? transfer RNA only messenger RNA only ribosomal RNA and transfer RNA only messenger RNA, ribosomal RNA, and transfer RNA 19. A. B. C. D. How many nucleotides would it take to carry the code for a protein with 4 amino acids? 4 8 12 16 20. A. B. C. D. Genes contain instructions for assembling DNA nucleotides. carbohydrates. nitrogen bases. proteins. DNA Processes Study Guide – Student- (Revised June 25, 2008) (printed 6/24/2017) p. 6