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Chapter 1 Outline • • • • • Section 1.1 Outline • 1.1 How Do Scientists Study Life? – Life Can Be Studied at ______________ ________________ – Scientific ________ Underlie All Scientific Inquiry – The Scientific _______is the Basis for Scientific Inquiry – Communication Is Crucial to Science – Science is a Human Endeavor – Scientific Theories Have Been Thoroughly Tested 1.1 1.2 1.3 1.4 1.5 Biologists and Life Evolution “Living Things” Life Diversity and Classification Knowledge of Biology and Everyday Life Levels of Organization • The living and nonliving world is organized at many levels Levels of Organization • All matter is formed of elements • An atom is the smallest particle of an element retaining the properties of an element • Atoms combine to form molecules • Molecules provide the building blocks for cells, the smallest unit of life 1 Levels of Organization • Some forms of life consist of single cells • In multicellular forms cells combine to form tissues • Tissues combine to form organs, which can be united as organ systems • Multicellular organisms are composed of multiple organ systems Levels of Organization • Organisms of the same type that are capable of interbreeding are called a species • A group of organisms of the same species living in a given area is a population • Interacting populations make up a community • A community and its nonliving environment is an ecosystem • The entire surface of the Earth, including living and nonliving components is the biosphere Scientific Principles • Biology is a scientific discipline • All scientific inquiry is based on a small set of assumptions or principles – Natural causality – Uniformity in space and time – Similar perception Natural Causality • Historical approaches to studying life 1. Belief that some events happen through supernatural forces (e.g. the actions of Greek gods) 2. Belief that all events can be traced to natural causes that we can comprehend (natural causality) • Natural Laws Apply Everywhere • Natural laws are uniform in space and time • This principle is key understanding biological events (e.g. evolution) that occurred before humans recorded them • Creationism is contrary to the principle of uniformity-in-time and natural causality – Creationists hold that different species were created one at a time by the direct intervention of a supernatural being, contrary to events we see happening today Corollary: Evidence gathered from nature has not been deliberately distorted to fool us Similar Perceptions • Assumption that all human beings perceive natural events in fundamentally the same way • Common perception allows us to accept observations of other humans as reliable • Common perception is usually not found in appreciation of art, poetry, and music, nor between cultures or religious beliefs – Value systems are subjective – Science requires objectively gathered data 2 The Scientific Method • Scientific inquiry is a rigorous method for making observations • The Scientific Method for inquiry follows 4 steps… 1. Observation of a phenomenon – Subsequent development of questions 2. Formulation of a hypothesis – A supposition that explains an observed phenomenon, leading to testable predictions The Scientific Method 3. Testing through experimentation – Additional controlled observations 4. Development of a conclusion – Evaluation of hypothesis in light of experimental data The Scientific Method The Scientific Method • Scientific experimentation tests the assertion that a single variable causes a particular observation • The experiment must rule out the influence of other possible variables on the recorded observations • Controls are incorporated into experiments • Controls keep untested variables constant • Scientific method is illustrated by Francesco Redi’s experiment 3 Limitations of the Scientific Method • Can never be sure all untested variables are controlled • Conclusions based on the experimental data must remain tentative • Results of experimentation must be communicated thoroughly and accurately to other scientists for repetition • Repetition by other scientists add verification that findings can be used as the basis for further studies Science Is a Human Endeavor • Human personality traits are part of “real science” • Scientists, like other people may be driven by _____, _______, __________ • Scientists __________ make mistakes • Accidents, lucky guesses, intellectual powers, and controversies with others ________ strongly to scientific advances Science Is a Human Endeavor Science is a Human Endeavor 1. In the 1920s, bacteriologist ________ _________ grew bacteria in cultures 2. One of the bacterial cultures became contaminated with a _____ 3. Fleming nearly destroyed the culture when he noticed the ______________ inhibited bacterial growth in the culture 4. Fleming hypothesized that the mold produced an _________ substance 5. Further tests using broth from pure Penicillium cultures lead to the discovery of the first antibiotic, _________ 6. Fleming continued beyond a lucky “accident” with further scientific investigation to a great discovery 7. “Chance favors the prepared mind” _________________ Scientific Theory Scientific Theory • A scientific theory ______ in definition from that of everyday usage – Many people use the word theory to mean hypothesis, and “educated guess” • A scientific theory is a general explanation for important natural phenomena – It is extensively and reproducibly ________ – It is more like a __________________ (e.g. the atomic, gravitational, and cell theories) – If compelling evidence arises, a theory may be ________ • New scientific evidence may prompt radical revision of existing theory • Example: the discovery of prions… • Before 1980, all known infectious diseases contained DNA or RNA • In 1982, Stanley Prusiner showed that the infectious sheep disease scrapie is caused by a ____________________________ ____________________________ 4 Scientific Theory • Prions have since been shown to cause “mad cow disease” and diseases in humans • The willingness of scientists to revise accepted belief in light of new data was critical to understanding and expanding the study of prions Science Is Based on Reasoning • Inductive Reasoning – Used in the development of scientific theories – A _______________ is created from many observations – e.g., the cell theory (all living things are made of one or more cells) arises from many observations that all indicate a cellular basis for life Unifying Theory of Biology Science Is Based on Reasoning • Deductive Reasoning – Generating hypotheses based on a wellsupported generalization (such as a theory) – e.g., based on the cell theory, any newly discovered organism would be expected to be composed of cells • Abundant evidence has been found to support evolutionary theory since Darwin and Wallace proposed it in the mid-1800s • Those who see evolution as “just a theory” don’t understand the scientific definition of a theory Unifying Theory of Biology • Evolution explains how diverse forms of life originated through changes in their genetic makeup – Modern organisms descended with __________ from pre-existing life forms – “Nothing in biology makes sense, except in the light of evolution” ______________________ Three Natural Processes Underlie Evolution • _____________ and _________________ formulated the basis of our modern understanding of evolution • Evolution arises as a consequence of three natural processes… 1. _________________ among members of a population 2. _____________ of those variations by offspring of parents carrying the variation 3. _________________ of individuals whose survival and enhanced reproduction are due to the favorable variations they carry 5 Genetic Variability • Genetic variation arises from segments of DNA (_______) • Changes in genes (_________) alter the informational content • Mutations arise from a number of sources – Mutations can occur from irradiation – Mutations occasionally arise from copying mistakes in ____ during cellular reproduction Natural Selection • Organisms that best meet environmental challenges leave the ______ offspring • Natural selection _________ genes that help organisms flourish Genetic Variability • Effects of mutation – No effect (harmless) – A decrease in organism’s ability to function – Death of the organism – An increase in an organism’s ability to survive and reproduce (rare) • Mutations occurring over millions of years and passed through many generations cause members of a species to be slightly different Natural Selection • _____________ are structures, physiological process, or behaviors that aid in survival and reproduction • ______________ that are good for one environment may be poor in another Natural Selection Natural Selection • Species that cannot adapt to environmental change go ________ (e.g. the dinosaurs, illustrated by the Triceratops • The many different habitats (environments) in an area coupled with evolutionary adaptive processes produce species variety or ______________ • Humans are responsible for ___________ the rate of environmental change (and therefore the rate of extinction of species) 6 Defining Life • Dictionary definition of life is: Living Things Are Composed of Cells • Living things are ______ and _________ – “___________________________________ _________________________________” • Living things are more than the sum of their parts; life is difficult to define • The complexity and ordered interactions of parts in living things gives rise to certain ___________ properties Living Things Are Composed of Cells • The cell theory states that the cell is the ____________________ • A single cell has an elaborate internal structure Homeostasis Living Things Are Composed of Cells • All cells contain: – ________ that provide information to direct the cell – __________, small specialized structures that perform specific functions – A ________________ that encloses the fluid cytoplasm and organelles from the outside world Living Things Respond to Stimuli • Organisms must maintain relatively constant internal conditions (_______________) • Organisms sense and respond to internal and external environmental stimuli – e.g. many organisms regulate body temperature – Sensory organs in animals can detect and respond to external stimuli like _____, ________, ______________ – Internal stimuli in animals are perceived by ________, _____________, ____________ – Plants and bacteria respond to stimuli as well (e.g. plants to ______, bacteria to available ____________ in the medium) • Homeostatic mechanisms include – ___________ in hot weather or dousing oneself with cool water – Metabolizing more food, basking in the sun, or turning up the thermostat in cold weather • Organisms still grow and change while maintaining homeostasis 7 Living Things Acquire Materials Living Things Acquire Materials • Materials and energy required to maintain organization, to grow, and to reproduce • Important materials (nutrients) acquired from air, water, soil, or other living things • Nutrients are continuously recycled among living and nonliving things Living Things Acquire Materials Living Things Acquire Materials • Nutrients are incorporated into the bodies of organisms • _____________ is the sum total of all the chemical reactions needed to sustain an organism’s life Living Things Grow • Every organism becomes larger over time – Plants, bird, and mammals grow by producing more cells to increase their mass – Bacteria grow by enlarging their cells; they also divide to make more individuals • Growth involves the conversion of acquired materials to molecules of the organism’s body • Organisms obtain energy in two ways – Plants and some single-celled organisms capture sunlight in ________________. – Other organisms consume energy-rich molecules in the bodies of other organisms • All energy that sustains life comes directly or indirectly from the _______ Living Things Reproduce Themselves • Organisms give rise to offspring of the same type (_________________) • The parent’s genetic material (DNA) is passed on to the offspring, creating __________ of life • ___________ of life occurs because offspring may be genetically different from their parents 8 Capacity to Evolve • The genetic composition of a whole species changes over many generations • _________ and __________ offspring allow a species to evolve • Evolutionary theory states that modern organisms descended with ___________ from pre-existing life-forms • _________________ is a process where organisms with certain adaptations survive and reproduce more successfully than others Categorizing Life • Domain Eukarya contains four subdivisions or kingdoms – Fungi – Plantae – Animalia – The “Protists” Prokaryotic and Eukaryotic Cells • Cell types named after presence or absence of a nucleus – The nucleus is a membrane-enclosed sac containing the ______________________ • Two cell types seen among all living things Categorizing Life • Organisms can be grouped into three domains – Bacteria (single, simple cells) – Archaea (single, simple cells) – Eukarya (one or more highly complex cells) Categorizing Life • There are exceptions to any simple set of rules used to distinguish the domains and kingdoms, but three characteristics are particularly useful – Cell type – The number of cells in each organism – Energy acquisition Prokaryotic and Eukaryotic Cells – _______________ (“true nucleus” in Greek) • Larger than prokaryotic cells • Contain a variety of organelles, including a nucleus • Cell type found only among members of Domain Eukarya – _______________ (“before nucleus” in Greek) • Only 1-2 micrometers in diameter • Lacking organelles or a nucleus • Cell type found in Domains________ and _________ 9 Unicellularity vs. Multicellularity • _____________ (single-celled) organisms found in: Unicellularity vs. Multicellularity • _____________ (many-celled) organisms found in Eukarya – Bacteria – Archaea – The protists in Eukarya – Kingdom Fungi – Kingdom Plantae – Kingdom Animalia Ways Organisms Acquire Energy Ways Organisms Acquire Energy • • ____________ (“self-feeders”) – Photosynthetic organisms that capture sunlight and store it in sugar and fats – Includes plants, some bacteria, and some protists Science Is Part of Everyday Human Existence • We can use the scientific method as we _________ things in nature • Applying scientific thought to natural observations does not decrease one’s sense of wonder and appreciation _______________ (“other-feeders”) – Organisms that acquire energy through ingesting molecules in the bodies of other organisms – Includes many ___________________ ___________________________________ _______________ – Size of food eaten varies from individual food molecules to ingestion and digestion of whole chunks Science Is Part of Everyday Human Existence • Scientific understanding and a sense of wonder about nature are not mutually exclusive 10 11