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EK: A variety of intercellular and intracellular signal transmissions mediate gene expression Signal Transmission within and between cells mediates gene expression  Cytokines and the immune system  Helper T cells release cytokines that stimulate the B and T cells to undergo proliferation to increase numbers during an immune response.  Growth factors released by cells stimulate cell division.  cAMP levels and bacteria metabolism  cAMP activates and increases the response in the lac operon in response to large quantities of lactose.  Ethylene production in fruit  Activates enzymes that cause enzymes to be produced that cause fruit to ripen. Signal transmission within and between cells mediates cell function.  Morphogens- Devlopment  Bicoid  Caudal  P53 genes  Change in tumor suppressor gene can lead to cancer.  HOX genes  Hox Genes and Body Plans