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Muscle System The word muscle means little mouse in Latin from the fancied resemblance of the muscle body contracting beneath the skin. Three Types of Tissues Skeletal: striated, voluntary, multinucleated Three Types of Tissues Cardiac: striated, involuntary, single nucleus per cell, and intercalated disks. Three Types of Tissues Smooth: nonstriated, involuntary, single nucleus, found in organ walls and blood vessel walls Functions of the Muscle System Produces body movements Stabilizes body positions Regulates organ volume Moves substances through the body Produces Heat 75% of the energy of muscles becomes heat 25% of the energy of muscles produces movement Muscles have a large blood supply At rest: 15-20% of the blood in the body goes to the muscles Maximum exertion: 80-85% of the blood in the body goes to the muscles Muscles have their own nerve supply Every muscle cell gets its own motor nerve ending Sensory neurons goes from the muscle to the spinal cord to the brain Properties of Muscle Tissues Electrical Excitability Ability to respond to certain stimuli by producing electrical signals Contractility Ability to shorten Extensibility Ability to stretch Elasticity Ability to rebound after stretching Shapes/Arrangements of Muscle Fiber Parallel Fascicles run side by side and they end in flat tendons Ex: sartorius Fusiform Ex. Biceps brachii Another type of fascicle arrangement, but the ends of the muscle taper toward the tendons. The belly of the muscle (the fleshy part in the middle) is more expanded than the ends Pennate the muscle fibers are short and the fascicles are directed obliquely (diagonally) toward a central tendon that runs the length of the muscle. fascicles insert into only one side of the tendon, the muscle is UNIPENNATE Ex:Extensor digitorum longus fascicles insert into the tendon from both sides, so that the muscle resembles a feather, the arrangement is BIPENNATE Ex: Rectus femoris Fascicles that attach obliquely (at a diagonal) from many directions to several tendons are called MULTIPENNATE Ex. deltoid CONVERGENT (triangular) pattern, the muscle has a broad origin and its fascicles converge toward a single tendon Ex. Pectoralis major Ex. Obicularis oculi Circular Fascicles are arranged to form a circle of muscle fibers. This arrangement is always found surrounding an external body opening. Gross Anatomy Each skeletal muscle is a separate organ composed of fibers. Connective tissues surround the muscle fibers and the whole muscle. Fascia: sheet/broad band of fibrous connective tissue Perimysium: surrounds groups of muscle fibers called fascicles Endomysium: separates individual muscle fibers Nerve and Blood Supply Generally, an artery and 1 or 2 veins accompany each nerve that penetrates a skeletal muscle. Neurons that stimulate muscular contractions are called somatic motor neuron Microscopic Anatomy Sarcolemma: plasma membrane that surrounds each muscle fiber Sarcoplasma: cytoplasm of the fiber and located within it Myofibrils: threadlike structures that run the length of the muscle fibers contractile elements of the skeletal muscle composed of myofilaments Two Types of Myofilaments 1. Myosin filament: thick and consist of a protein called myosin 2. Actin filament: thin, consist of a protein called actin Myosin and actin filaments form repeating units called sarcomeres. Basic unit of muscle contraction Hundreds of sarcomeres join end to end to form a myofibril Joined at the ends by interweaving filaments called Z line Filaments overlap producing striation A Band: darker middle portion of the sarcomere and extends the entire length of the myosin I Band: lighter area of the sarcomere, contains only actin H Zone: located in the center of of each A band and contains only myosin M Line: supporting proteins holding the myosin at the center of the H zone Zebras In A Hot Motel Z line, I band, A band, H Zone, M line Zebras In A Hot Motel Z line, I band, A band, H zone, M line Sarcoplasmic reticulum: fluid-filled system of membranous sacs that encircle each myofibril. Stores calcium (Ca 2+ ) during muscle relaxation Releases calcium to trigger muscle contraction Terminal cisterns : dilated end sacs of the sarcoplasmic reticulum T tubules and terminal cisterns form a triad of the sacroplasmic reticulum Troponin tropomyosin Muscle Metabolism Muscle fibers have 3 sources for ATP production: Creatine phosphate Anaerobic cellular respiration Aerobic cellular respiration Creatine Phosphate Energy rich molecule unique to muscle fibers Provides enough energy for muscles to contract maximally for about 15 minutes. Ex: 100 meter dash. Anaerobic Cellular Respiration ATP producing reactions that do not require oxygen Produces energy for about 30-40 seconds of maximal muscle activity. Ex: 200 meter race Aerobic Cellular Respiration Oxygen-requiring reactions that produces ATP Used when muscle activity lasts longer than half a minute.