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An introduction to Metabolism (The Encylpedia of Earth, 2006) ATP Adenosine Triphosphate • The primary source of free energy in living cells • Structure: nitrogenous base adenine attached to the 5-carbon sugar Ribose which is attached (bound) to a chain of 3 phosphate groups. (see p65) Image taken from: http://chemistry.about.com/od/factsstructures/ig/Chemical-Structures---A/AdenosineTriphosphate--ATP-.htm How is energy obtained from ATP? • Enzyme ATPase catalyzes the hydrolysis of the phosphate on the terminal end of the molecule making ADP • One Pi (inorganic phosphate) molecule is released with a ton of energy! (p65) • But the energy isn’t always freely released: the Pi can go on to PHOSPHORYLATE (add a phosphate to) other molecules changing their shape and making them more active (like in active transport) ATP cycle video The Big Picture of Cellular respiration: • Photoautotrophs, like green plants, transform light energy into chemical potential energy (glucose and other carbohydrates) • Heterotrophs (animals, fungi, bacteria…) rely on autotrophs for energy. • Glucose is the primary energy source for (almost) all organisms. The energy is extracted by enzymes doing redox reactions • When the bonds are broken, more stable compounds are formed and so energy is released • Released energy is “trapped” and stored as ATP (34% of it anyways) Aerobic cellular respiration: C6H12O6 + 6O2 6CO2 + 6H2O • Aerobic means oxygen is used • Accomplished by 20 chemical reactions (not by breathing)… the equation above is a summary! (initial reactants and final products only) • Glucose and oxygen don’t just react together spontaneously… the activation energy barrier must be overcome! • This is done by enzymes….lots of enzymes Glucose video