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HOW TO CONTROL CANCER Putting Science into Practice Dr. L. Martin Jerry MD PhD Director W.H.O. Collaborating Centre for Cancer Control Tom Baker Cancer Centre Calgary, Canada THE AIM OF CANCER CONTROL Reduction of Cancer Incidence, Morbidity & Mortality by: • • • • Prevention Early Diagnosis Treatment Palliative Care REV THE W.H.O. PUBLIC HEALTH MODEL FOR CANCER CONTROL • Assess the magnitude of the cancer problem • Evaluate possible strategies for cancer control • Choose priorities for initial cancer control activities of prevention, screening, therapy and palliative care • Set measurable cancer control objectives REV PRIMARY PREVENTION OF CANCER • • • • • • • Tobacco Control Diet Control of Alcohol Consumption Occupation and Environment Infections (viruses and parasites) Reducing Sunlight Exposure Sexual and Reproductive Factors REV PRIMARY PREVENTION Tobacco Control • Education • Legislation • National Leadership REV PRIMARY PREVENTION DIET • Education • Legislation • National Leadership REV PRIMARY PREVENTION Alcohol • Education • Legislation • National Leadership REV PRIMARY PREVENTION Occupational Hazards • Education • Legislation • National Leadership REV PRIMARY PREVENTION Viral Hepatitis B • Education • Legislation • National Leadership REV PRIMARY PREVENTION Overexposure to Sunlight • Education • Legislation • National Leadership REV Primary Prevention Sexual and Reproductive Factors • Hormonal influences • Sexually transmitted diseases REV EARLY DETECTION Education REV EARLY DETECTION Downstaging REV EARLY DETECTION Downstaging for Cervical Cancer REV EARLY DETECTION Downstaging for Oral Cancer REV EARLY DETECTION Screening REV EARLY DETECTION Screening for Cervical Cancer REV EARLY DETECTION Screening for Breast Cancer REV EARLY DETECTION • • • • • • • • Esophagus Stomach Colon and rectum Liver Lung Ovary Bladder Prostate TREATMENT • Surgery • Radiotherapy • Chemotherapy General principles REV TREATMENT The Role of Surgery REV TREATMENT The Role of Radiation Therapy REV TREATMENT The Role of Chemotherapy REV TREATMENT The Role of Hormonal Therapy REV TREATMENT The Role of Biological Therapy REV TREATMENT How Effective is Cancer Treatment ? REV TREATMENT • Policies –Treatment Policies –Referral Policies REV PALLIATIVE CARE • Palliative Medicine is the study and management of patients with active, progressive, far-advanced disease for whom the prognosis is limited and the focus of care is the quality of life.” Doyle et al (Eds). Oxford Textbook of Palliative Medicine. P3. Oxford University Press, Oxford, 1996. REV SUMMARY • Cancer is a Disease of Lifestyle With Both Host Resistance and Genetic Components • 60-80% of the Risk factors for Cancer are Avoidable • Putting Science Into Practice Leads to a Public Health Approach for Cancer Control Which Integrates Prevention, Screening, Treatment and Palliation at the National Level CANCER LECTURE 2 • REFERENCES • INTERNET RESOURCES FOR CANCER • REVIEW QUESTIONS • LAST SLIDE