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DNA Chapter 4 Section 1 Notes The Pieces of the Puzzle _______- deoxyribonucleic acid - found in all _______ cells - contains information for ________ passed on from parents to offspring *Must be able to give ___________ * Must be able to be __________ The Pieces of the Puzzle Nucleotides: The Subunits of DNA ____________- part of DNA - made of: -________ -phosphate -nitrogenous base -4 bases ______ (A) thymine (T) ______ (G) cytosine (C) The Pieces of the Puzzle Chargaff’s Rules Erwin Chargraff 1950’s Biochemist Adenine = _______ Guanine = _______ The Pieces of the Puzzle Franklin’s Dicscovery Rosalind Franklin Made images of DNA X-Ray _____________ Suggested DNA had ______ shape The Pieces of the Puzzle Watson and Crick’s Model James Watson and Francis Crick DNA must be long twisted ___________ Built first model Fit Chargraff’s and Franklin’s findings Helped explain how DNA is ___________ A Place in History Imagine you have just discovered the structure of DNA. Wow!! What do you do know??? You are going to make a poster to present your findings to fellow scientists. You will be working with your lab islands on this activity. Must have: Model of DNA Description (be detailed) Tell how you discovered it Your names DNA’s Double Structure Double _________ Twisted ladder Two sides Alternating _____ & phosphate Rungs Pair of ________ Adenine with thymine Cytosine with guanine Matching bases always present in _____ amounts Making Copies of DNA DNA __________ (copies) Base pairs are complementary CGAC bonds with __________ Making Copies of DNA How Copies Are Made DNA “_______” down middle of ________ pairs Single bases have new _______________ bases paired with them On new strands of DNA half is “new” and half is “old” http://www.zerobio.com/drag_gr9/DNA/dn a.htm Making Copies of DNA When Copies Are Made Copied every time a cell _________ Each cell gets a copy Job is done by ___________