Download CASE 2 - Zoomify (LUMC)

Liver Pathology, CASE 2
• 53 year-old with chronic alcohol and drug abuse
who has been in numerous rehabilitation facilities in
the past now presents with abdominal pain after a
3-week alcoholic “binge.”
Identify the organ
Describe the gross findings.
Diagnosis?
The autopsy specimen of the liver reveals
cirrhosis. The liver is discolored yellow-brown and has a nodular surface.
Identify the organ
Describe the gross findings.
Diagnosis?
Cirrhosis (alcoholic)
The liver reveals fatty changes and nodularity.
Cirrhosis The surface of the liver is nodular.
Identify the organ
Describe the gross findings.
Diagnosis?
Cirrhosis (alcoholic)
A cut section of the liver reveals micronodules and fatty change.
Bands of fibrosis
Producing pseudolobules
Describe the lower power histologic findings
A - Pseudolobule
B - Fibrosis
Describe the findings in this trichrome stain (stains collagen
blue)
Few neutrophils
with hepatocyte
necrosis
Steatosis
Mallory bodies
Diagnosis?
•
Acute alcoholic hepatitis
superimposed on alcoholic cirrhosis.